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21401por Li, Jinglei, Tong, Hanxing, Li, Dongping, Jiang, Qiuyu, Zhang, Yong, Tang, Wenqing, Jin, Dayong, Chen, She, Qin, Xinyu, Zhang, Si, Xue, Ruyi“…KEGG pathway analysis and the Gene ontology category indicated that these genes were associated with the regulation of mRNA alternative splicing and metabolic balance. …”
Publicado 2021
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21402“…The R package and other tools such as m6A2Target database, Gene ontology (GO) functional and Kyoto encyclopedia of genes and genomes (KEGG) pathway analyses, gene set variation analysis (GSVA), Search Tool for the Retrieval of Interacting Genes (STRING), starBase, miRDB and Cytoscape software were applied for bioinformatics analysis to investigate the downstream molecular mechanisms and upstream regulatory mechanisms for distinctly expressed regulators. …”
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21403por Barcelona, Veronica, Montalvo-Ortiz, Janitza L., Wright, Michelle L., Nagamatsu, Sheila T., Dreisbach, Caitlin, Crusto, Cindy A., Sun, Yan V., Taylor, Jacquelyn Y.“…Co-methylation analyses showed correlations with preterm birth in gene ontology and KEGG pathways. Functional annotation analysis revealed enrichment for pathways related to central nervous system and sensory perception. …”
Publicado 2021
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21404por Shen, Wen, Wang, Shukun, Wang, Ruili, Zhang, Yang, Tian, Hong, Yang, Xiaolei, Wei, Wei“…The potential target genes of miRNA were identified using miRanda (v3.3a) and TargetScan (v6.0) with default settings. Gene Ontology (GO) and Reactome pathway analyses were performed. …”
Publicado 2021
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21405por Jing, Xia“…After analysis and categorization of the publications, UMLS was found to be used in the following emerging themes or areas (the number of publications and their respective percentages are given in parentheses): natural language processing (230/975, 23.6%), information retrieval (125/975, 12.8%), terminology study (90/975, 9.2%), ontology and modeling (80/975, 8.2%), medical subdomains (76/975, 7.8%), other language studies (53/975, 5.4%), artificial intelligence tools and applications (46/975, 4.7%), patient care (35/975, 3.6%), data mining and knowledge discovery (25/975, 2.6%), medical education (20/975, 2.1%), degree-related theses (13/975, 1.3%), digital library (5/975, 0.5%), and the UMLS itself (150/975, 15.4%), as well as the UMLS for other purposes (27/975, 2.8%). …”
Publicado 2021
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21406“…A total of 14,849 lncRNAs were identified, and 2196 lncRNAs showed significant differences at different time points post A. hydrophila infection. Gene Ontology (GO) annotation and Kyoto Encyclopedia of Genes and Genomes (KEGG) pathway analyses showed that the target genes of the differentially expressed lncRNAs were enriched in several pathways related to immune such as apoptosis, inflammation, and immune response. …”
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21407por Fang, Yuan, Yang, Yang, Zhang, XiaoLi, Li, Na, Yuan, Bo, Jin, Li, Bao, Sheng, Li, MengGe, Zhao, Dan, Li, LingRui, Zeng, Zhong, Huang, HanFei“…Weighted gene co-expression network analysis followed by Gene Ontology (GO) enrichment analyses were conducted on the database. …”
Publicado 2021
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21408por Studer, Jamie M, Kiefer, Zoe E, Goetz, Brady M, Keating, Aileen F, Baumgard, Lance H, Rambo, Zachary J, Schweer, Wesley P, Wilson, Mark E, Rapp, Christof, Ross, Jason W“…Compared with CON, 188, 382, and 401 proteins were differentially abundant (P < 0.10) in TRT1, TRT2, and TRT3, respectively. Gene Ontology enrichment software revealed that proteins involved in P(4) signaling and cholesterol synthesis were downregulated in CL of gilts fed Mn–amino acid complex compared with controls. …”
Publicado 2021
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21409“…METHODS: Data were downloaded from the TCGA database and Univariate Cox regression analysis was performed to determine AS events associated with OC prognosis.Eight prognostic models of OC were constructed in R package, and the accuracy of the models were evaluated by the time-dependent receiver operating characteristic (ROC) curves.Eight types of survival curves were drawn to evaluate the differences between the high and low risk groups.Independent prognostic factors of OC were analyzed by single factor independent analysis and multi-factor independent prognostic analysis.Again, Univariate Cox regression analysis was used to analyze the relationship between splicing factors(SF) and AS events, and Gene Ontology(GO) and Kyoto Encyclopedia of Genes and Genomes(KEGG) enrichment analysis were performed on OS-related SFs to understand the pathways. …”
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21410“…Pearson correlation analysis was used to select genes with an opposite direction of expression and differences in methylation levels, and then Gene Ontology (GO) function and Kyoto Encyclopedia of Genes and Genomes (KEGG) pathway analysis were performed. …”
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21411“…DEGs were identified using limma package of R software, and co-expressed genes were identified using Venn diagrams. Then, the gene ontology (GO) and Kyoto Encyclopedia of Genes and Genomes (KEGG) pathway enrichment analyses were performed to explore the biological functions and signaling pathways. …”
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21412por Abdelmanova, Alexandra S., Dotsev, Arsen V., Romanov, Michael N., Stanishevskaya, Olga I., Gladyr, Elena A., Rodionov, Andrey N., Vetokh, Anastasia N., Volkova, Natalia A., Fedorova, Elena S., Gusev, Igor V., Griffin, Darren K., Brem, Gottfried, Zinovieva, Natalia A.“…One of the RW-specific sweep regions harbored the known domestication gene, TSHR. Gene ontology and functional annotation analysis provided additional insight into a functional coherence of genes in the sweep regions. …”
Publicado 2021
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21413“…To counter low validity and usefulness, we propose the following for policy makers and administrative management when developing and implementing waiting time monitoring: communicate guidelines with instructions for operationalization, address barriers to implementation, ensure quality through monitoring of implementation and adherence to guidelines, develop IT ontology together with professionals, avoid parallel measurement infrastructures, ensure waiting times are presented to suit management needs, provide timely waiting time data, enable the study of single cases, minimize manual data entry, and perform spot-checks or external validity checks. …”
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21414por Ge, Yanzhi, Chen, Zuxiang, Fu, Yanbin, Xiao, Xiujuan, Xu, Haipeng, Shan, Letian, Tong, Peijian, Zhou, Li“…By integrating multiple gene data sets, specific differentially expressed genes (DEGs) were identified. The Gene Ontology (GO) functional annotation, Kyoto Encyclopedia of Genes and Genomes (KEGG) pathways and protein–protein interaction (PPI) network analysis of DEGs were conducted to determine hub genes and pathways. …”
Publicado 2021
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21415por Bhattarai, Surendra, Fu, Yong-Bi, Coulman, Bruce, Tanino, Karen, Karunakaran, Chithra, Biligetu, Bill“…About 60% of DEGs were assigned to known gene ontology (GO) categories. The genes were involved in transmembrane protein function, photosynthesis, carbohydrate metabolism, defense against oxidative damage, cell wall modification and protection against lipid peroxidation. …”
Publicado 2021
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21416por Xiong, Rui, He, Ting, Wang, Yamei, Liu, Shifan, Gao, Yameng, Yan, Hanwei, Xiang, Yan“…In chromosome mapping and gene replication analysis, 8 tandem duplication and 11 segmental duplication events demonstrated that PnCYP genes were continuously replicating during their evolution. Gene ontology (GO) analysis annotated the functions of 188 PnCYPs into 21 functional subclasses, suggesting the functional diversity of these gene families. …”
Publicado 2021
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21417“…METHODS: To analyze the impact of EZR expression on overall survival and free diseases survival of PC patients, we screened abnormally expressed EZR in PC using the Gene Expression Omnibus database (GEO database) and The Cancer Genome Atlas (TCGA) database. Following, Gene Ontology (GO)-based functional analysis and Gene set enrichment analysis (GSEA) was performed to predicate the possible biological processes in which EZR were involved. …”
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21418por Zhang, Fangyuan, Yu, Shicheng, Wu, Pengjie, Liu, Liansheng, Wei, Dong, Li, Shengwen“…Two subtypes of cancer cells were identified, pseudotime trajectory analysis and gene ontology (GO) analysis were conducted with the monocle and clusterProfiler packages. …”
Publicado 2021
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21419“…METHODS: In this study, whole-transcriptome sequencing analysis was conducted to study the ncRNA and mRNA profiles of parental SiHa cells and DDP resistant SiHa/DDP cells. Gene ontology (GO) and Kyoto Encyclopedia of Genes and Genomes (KEGG) were performed for pathway analysis based on the selected genes with significant differences in expression. …”
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21420por Luo, Jieyan, Hu, Qipeng, Gou, Maling, Liu, Xiaoke, Qin, Yi, Zhu, Jiao, Cai, Chengzhi, Tian, Tian, Tu, Zegui, Du, Yijia, Deng, Hongxin“…Meanwhile, we performed Gene Ontology (GO) and Kyoto Encyclopedia of Genes and Genomes (KEGG) pathway analysis on the expression data of MAPs and their 50 frequently altered neighbor genes in NSCLC tissues. …”
Publicado 2021
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