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21421“…In addition, the biological functions of genes in the ceRNA network were also annotated by Gene Ontology and Kyoto Encyclopedia of Genes and Genomes. …”
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21422“…METHODS: The transcriptome data of colon cancer and clinical characteristics were downloaded from The Cancer Genome Atlas (TCGA) database. Gene ontology (GO), Kyoto Encyclopedia of Genes and Genomes (KEGG) analysis, and Gene Set Enrichment Analysis (GSEA) were performed to elucidate the gene functions and relative pathways. …”
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21423por Song, Jun-Wei, Zhu, Jing, Wu, Xing-Xuan, Tu, Ting, Huang, Jing-Qiang, Chen, Guan-Zi, Liang, Li-Yin, Zhou, Chun-Hui, Xu, XingZhi, Gong, Li-Yun“…Immunoprecipitation-mass spectrometry and gene ontology analysis demonstrated that GOLPH3 interacts with cytoskeleton-associated protein 4 (CKAP4) in exosome-mediated distal metastasis. …”
Publicado 2021
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21424por Olech, Monika, Ropka-Molik, Katarzyna, Szmatoła, Tomasz, Piórkowska, Katarzyna, Kuźmak, Jacek“…DEGs detected between the control group and groups with a proviral load were found to be significantly enriched in several gene ontology (GO) terms, including an integral component of membrane, extracellular region, response to growth factor, inflammatory and innate immune response, transmembrane signaling receptor activity, myeloid differentiation primary response gene 88 (MyD88)-dependent toll-like receptor signaling pathway as well as regulation of cytokine secretion. …”
Publicado 2021
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21425por Zhang, Mi, Zhao, Wei, Liu, Shanshan, Liu, Haichuan, Liu, Liang, Peng, Qiling, Du, Chengyou, Jiang, Ning“…Survival analysis, Gene Ontology (GO), and Kyoto Encyclopedia of Genes and Genomes enrichment pathway (KEGG) analyses were performed using R software. …”
Publicado 2021
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21426por Li, Yanxin, Ma, Ke, Xie, Qi, Zhang, Xianwei, Zhang, Xiulei, Chen, Kui, Kong, Lingfei, Qian, Rongjun“…Based on the mRNA expression of HOXD10, GBM patients from TCGA database were divided into low- and high-HOXD10 expression groups to analyze the Gene Ontology (GO) and Kyoto Encyclopedia of Genes and Genomes (KEGG) pathways, and construct a lncRNA-miRNA-mRNA network and a protein–protein interaction (PPI) network. …”
Publicado 2021
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21427por Charras, Amandine, Garau, Jessica, Hofmann, Sigrun R., Carlsson, Emil, Cereda, Cristina, Russ, Susanne, Abraham, Susanne, Hedrich, Christian M.“…Furthermore, patients with skin psoriasis can be discriminated from PsA patients [1,861 DMPs, 20 DMRs (≥5 CpGs per region), 4 DMRs (≥10 CpGs per region)]. Gene ontology (GO) analyses considering genes with ≥1 DMP in their promoter delivered methylation defects in skin psoriasis and PsA primarily affecting the BMP signaling pathway and endopeptidase regulator activity, respectively. …”
Publicado 2021
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21428por Yuan, Zehu, Ge, Ling, Sun, Jingyi, Zhang, Weibo, Wang, Shanhe, Cao, Xiukai, Sun, Wei“…Protein protein interaction (PPI) network, Gene Ontology (GO) and Kyoto Encyclopedia of Genes and Genomes (KEGG) enrichment analyses were implemented to investigate the potential functions of DETs. …”
Publicado 2021
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21429por Tatsumi, Kouko, Kinugawa, Kaoru, Isonishi, Ayami, Kitabatake, Masahiro, Okuda, Hiroaki, Takemura, Shoko, Tanaka, Tatsuhide, Mori, Eiichiro, Wanaka, Akio“…Unbiased classification of gene expression profiles and subsequent gene ontology analyses revealed that the majority of Olig2-astrocytes belonged to an astrocytic cluster that is enriched for transporter-related genes. …”
Publicado 2021
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21430por Arora, Devender, Park, Jong-Eun, Lim, Dajeong, Choi, Bong-Hwan, Cho, In-Cheol, Srikanth, Krishnamoorthy, Kim, Jaebum, Park, Woncheoul“…Subsequently, Motif analysis for DMRs was performed to understand the role of the methylated motif for tissue-specific differentiation. Gene ontology studies revealed association with collagen fibril organization, the Bone Morphogenetic Proteins (BMP) signaling pathway in backfat and cholesterol biosynthesis, bile acid and bile salt transport, and immunity-related pathways in methylated genes expressed in the liver. …”
Publicado 2021
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21431“…In early response to CGMMV infection, 422 differentially methylated genes (DMGs) were identified, most of which were hypomethylated, and probably associated with the increased expression of watermelon m(6)A demethylase gene ClALKBH4B. Gene Ontology (GO) analysis indicated quite a few DMGs were involved in RNA biology and stress responsive pathways. …”
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21432“…In addition, SRMS expression was correlated with infiltrating levels of CD4+ T cells, CD56dim, MEM B, Neutrophils, Th2, Th17, and Act DC. The gene ontology (GO) analysis of SRMS-associated immunomodulators and immune cell marker genes showed that they were mainly enriched in the immune microenvironment molecule-related signals. …”
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21433por Vogt, Lars“…This can be achieved by using ontologies and through representing them as semantic graphs. …”
Publicado 2021
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21434por Dai, Lijun, Zhang, Quanwei, Shi, Jun, Bai, Xu, An, Xiaoxiao, Zhang, Bohao, Zhang, Yong, Zhao, Xingxu“…Expression levels were significantly higher at 6 years of age. Gene ontology (GO) and pathway analysis enrichment revealed that NR1D1 may directly regulate the synthesis and metabolism of steroid hormones via interaction with different targets, while NR4A2 may indirectly regulate the synthesis and metabolism of steroid hormones. …”
Publicado 2021
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21435“…The StarBase and TransmiR databases were employed to predict target genes and transcription factors of the differentially expressed miRNAs (DE-miRNAs). Gene Ontology (GO) and Kyoto Encyclopedia of Genes and Genomes (KEGG) pathway analyses were conducted to predict biological functions. …”
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21436por Lin, Jing, Zeng, Jing, Liu, Sha, Shen, Xin, Jiang, Nan, Wu, Yue-Song, Li, Hong, Wang, Long, Wu, Jian-Ming“…Next, network pharmacology approaches were carried out to identify the targets of DMAG. Gene Ontology (GO) and Kyoto Encyclopedia of Genes and Genomes (KEGG) pathway enrichment analyses were performed to elucidate the underling mechanism of DMAG against thrombocytopenia. …”
Publicado 2021
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21437“…These genes were further analyzed using Lasso to establish a model. Gene Ontology (GO) and Kyoto Encyclopedia of Genes and Genomes (KEGG) were used for the functional analysis. …”
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21438por Li, Jia-xin, Cao, Xun-jie, Huang, Yuan-yi, Li, Ya-ping, Yu, Zi-yuan, Lin, Min, Li, Qiu-ying, Chen, Ji-chun, Guo, Xu-guang“…Kyoto Encyclopedia of Genes and Genomes (KEGG) and Gene Ontology (GO) were applied to illustrate the biological functions of genes in these modules. …”
Publicado 2021
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21439“…DEGs were assessed by Gene Ontology biological process (GO-BP) and Kyoto Encyclopedia of Genes and Genomes (KEGG) analyses. …”
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21440por Herold, Rosanna, Scholtysik, René, Moroniak, Selina, Weiss, Christel, Ishikawa, Hiroshi, Schroten, Horst, Schwerk, Christian“…The transcriptome analysis of HIBCPP cells following infection with Nm demonstrated specific regulation of genes involved in the immune response dependent on Erk1/2 signalling. Gene ontology (GO) analysis confirmed loss of MAPK signalling after Erk1/2 inhibition and revealed an additional reduction of cellular responses including NFκB and JAK-STAT signalling. …”
Publicado 2021
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