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22101por Huang, Xiaoping, Zhang, Hongyu, Wang, Qiang, Guo, Rong, Wei, Lingxia, Song, Haiyan, Kuang, Weigang, Liao, Jianglin, Huang, Yingjin, Wang, Zhaohai“…Through weighted gene co-expression network analysis (WGCNA), 22 continuously down-expressed lncRNAs targeting 812 co-expressed mRNAs and 48 continuously up-expressed lncRNAs targeting 1209 co-expressed mRNAs were considered to be significantly associated with flag leaf senescence. Gene Ontology results suggested that the senescence-associated lncRNAs targeted mRNAs involving in many biological processes, including transcription, hormone response, oxidation–reduction process and substance metabolism. …”
Publicado 2021
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22102por Chen, Zhengjie, Tang, Dengguo, Ni, Jixing, Li, Peng, Wang, Le, Zhou, Jinhong, Li, Chenyang, Lan, Hai, Li, Lujiang, Liu, Jian“…These 16,161 genes were annotated to 52 gene ontology (GO) terms, including most of primary and secondary metabolic pathways. …”
Publicado 2021
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22103por Wu, Huaying, Gong, Ke, Qin, You, Yuan, Zhiying, Xia, Shuaishuai, Zhang, Shiying, Yang, Jingjing, Yang, Ping, Li, Liang, Xie, Mengzhou“…MATERIALS AND METHODS: Encyclopedia of Traditional Chinese Medicine (ETCM) database was used to determine the meridian tropism, active components and target genes of XG-1. Gene ontology (GO) analysis and Kyoto Encyclopedia of Genes and Genomes (KEGG) functional enrichment analysis were conducted by R Cluster Profiler package (3.14.3). …”
Publicado 2021
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22104por Tang, Yun, Yang, Xiaobo, Shu, Huaqing, Yu, Yuan, Pan, Shangwen, Xu, Jiqian, Shang, You“…AKI-DEGs and septic-shock-DEGs were identified using the two datasets. Subsequently, Gene Ontology (GO) functional analysis, Kyoto Encyclopedia of Genes and Genomes (KEGG) pathway enrichment analysis, and protein-protein interaction (PPI) network analysis were performed to elucidate molecular mechanisms of DEGs. …”
Publicado 2021
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22105“…By investigating the clinical values of GMFG using The Cancer Genome Atlas (TCGA) data and the functional mechanisms of GMFG through analyses of Gene Ontology (GO) and Kyoto Encyclopedia of Genes and Genomes (KEGG) pathway enrichments, this study was aimed to better understand the impact of GMFG in pan-cancers and to draw more attentions for the future research of GMFG. …”
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22106por Hong, Namki, Lee, Seunghyun, Kim, Kyoungjin, Jeong, Jong Joo, Kim, Sang Kyum, Jo, Se-Young, Kim, Sangwoo, Rhee, Yumie“…Carcinoma-specific DEGs include upregulation of GRIN2A, LYPD1, and SOX2 and downregulation of ENTPPL, MYO3B, and PIK3C2G. Gene ontology enrichment revealed that these DEGs were mainly involved in the binding of cell adhesion molecule, actin, and Rho GTPase, and extracellular matrix structural constituent. …”
Publicado 2021
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22107por Meijer, Bartolomeus J., Smit, Wouter L., Koelink, Pim J., Westendorp, Barbara F., de Boer, Ruben J., van der Meer, Jonathan H. M., Vermeulen, Jacqueline L. M., Paton, James C., Paton, Adrienne W., Qin, Jun, Dekker, Evelien, Muncan, Vanesa, van den Brink, Gijs R., Heijmans, Jarom“…We identified a unique set of transcription factors with altered activation upon ER stress. Gene ontology analysis showed that transcription factors with diminished binding were involved in cellular differentiation processes. …”
Publicado 2021
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22108“…Enrichment analysis, based on Gene Ontology (GO) and Kyoto Encyclopedia of Genes and Genomes (KEGG) database, was performed to determine major biological functions and pathways involved. …”
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22109por Dai, Jin, Nishi, Akihiro, Li, Zhe-Xuan, Zhang, Yang, Zhou, Tong, You, Wei-Cheng, Li, Wen-Qing, Pan, Kai-Feng“…Gene set enrichment analyses were conducted to explore the Gene Ontology and Kyoto Encyclopedia of Genes and Genomes pathways simultaneously enriched for multiple GC prognostic outcomes. …”
Publicado 2021
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22110“…Additionally, cis-acting element prediction shows that all BnaDELLA genes contain light, stress, and hormone-responsive elements on their promoters. The gene ontology (GO) enrichment report indicated that the BnaDELLA gene family might regulate stress responses. …”
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22111por Lu, Jiajie, Peng, Yuecheng, Huang, Rihong, Feng, Zejia, Fan, Yongyang, Wang, Haojian, Zeng, Zhaorong, Ji, Yunxiang, Wang, Yezhong, Wang, Zhaotao“…The DEGs overlapping across both datasets were functionally annotated by Gene Ontology (GO) and Kyoto Encyclopedia of Genes and Genomes (KEGG) analyses. …”
Publicado 2021
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22112por Griffen, Ti’ara L., Dammer, Eric B., Dill, Courtney D., Carey, Kaylin M., Young, Corey D., Nunez, Sha’Kayla K., Ohandjo, Adaugo Q., Kornblau, Steven M., Lillard, James W.“…METHODS: Networks were investigated by using a novel weighted gene network co-expression analysis method and examining overrepresentation of upstream regulators and signaling pathways within co-expressed transcriptome modules across clinically annotated transcriptomes from CLL patients (N = 203). Gene Ontology analysis was used to identify biological functions overrepresented in each module. …”
Publicado 2021
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22113por Zhang, Yu, Huang, Xiaofeng, Liu, Jin, Chen, Guo, Liu, Chengjun, Zhang, Sen, Li, Jiaxin“…The differentially expressed mRNAs (DEmRNAs) and lncRNAs (DElncRNAs) in group of bone metastasis vs lung metastasis and bone metastasis vs liver metastasis, as well as the overlap of the two groups, were identified. Gene ontology (GO) and Kyoto Encyclopedia of Genes and Genomes (KEGG) pathway analysis and protein–protein interaction (PPI) network construction of DEmRNAs were conducted. …”
Publicado 2021
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22114por Dong, Cuicui, Tian, Xin, He, Fucheng, Zhang, Jiayi, Cui, Xiaojian, He, Qin, Si, Ping, Shen, Yongming“…The overlapping genes were used for pathway and Gene Ontology (GO) functional enrichment analysis using the Metascape online tool. …”
Publicado 2021
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22115“…Finally, risk-related DEGs were identified in both cohorts and subjected to enrichment analyses for Gene Ontology (GO), Kyoto Encyclopedia of Genes and Genomes (KEGG) and immune infiltration. …”
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22116“…Subsequently, the gene ontology (GO) and Kyoto Encyclopedia of Genes and Genomes (KEGG) pathway enrichment analysis were performed on the genes in the network to predict the potential underlying mechanisms and functions of circRNAs in LUAD. …”
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22117“…Differential expression analyses for each tissue type, between non-radiated and radiated samples, were performed incorporating RIN score, tissue type, and radiation status into the statistical model. Using the Gene Ontology (GO), an enrichment analysis was performed on the significant genes from the differential expression analyses. …”
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22118por Ranjan, Manish, Lee, Oukseub, Cottone, Gannon, Mirzaei Mehrabad, Elnaz, Spike, Benjamin T., Zeng, Zexian, Yadav, Shivangi, Chatterton, Robert, Kim, J. Julie, Clare, Susan E., Khan, Seema A.“…These hormone-induced effects were reversed upon exposure to TPA and MFP (p < 0.01 for both). Gene Ontology analysis of RNA-sequencing data showed EP-induced enrichment of several pathways, with the largest effect on Wnt signaling in MSC, significantly repressed by PR inhibitors. …”
Publicado 2021
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22119“…Then Protein–protein Interaction (PPI) network analysis, Gene Ontology (GO) functional analysis and Kyoto Encyclopedia of Genes and Genomes (KEGG) analysis were performed to excavate the functional interaction of these two groups of DEGs and the common DEGs. …”
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22120por Sun, Wentian, Song, Yidan, Xia, Kai, Yu, Liyuan, Huang, Xinqi, Zhao, Zhihe, Liu, Jun“…Furthermore, bioinformatic analyses including volcano plots, Venn plots, clustering analysis, Gene Ontology (GO), Kyoto Encyclopedia of Genes and Genomes (KEGG) pathway, gene sets enrichment analysis, and protein-protein interaction analysis were conducted. …”
Publicado 2021
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