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22221por Wen, Dong-yue, Lin, Peng, Liang, Hai-wei, Yang, Xia, Li, Hai-yuan, He, Yun, Yang, Hong, Chen, Gang“…In addition, the related genes of CTD-2547G23.4 gathered from The Atlas of Noncoding RNAs in Cancer (TANRIC) database and Multi Experiment Matrix (MEM) were assessed with Gene Ontology (GO), Kyoto Encyclopedia of Genes and Genomes, Protein Analysis Through Evolutionary Relationships and protein–protein interaction (PPI) networks. …”
Publicado 2018
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22222por Ji, Xuemei, Bossé, Yohan, Landi, Maria Teresa, Gui, Jiang, Xiao, Xiangjun, Qian, David, Joubert, Philippe, Lamontagne, Maxime, Li, Yafang, Gorlov, Ivan, de Biasi, Mariella, Han, Younghun, Gorlova, Olga, Hung, Rayjean J., Wu, Xifeng, McKay, James, Zong, Xuchen, Carreras-Torres, Robert, Christiani, David C., Caporaso, Neil, Johansson, Mattias, Liu, Geoffrey, Bojesen, Stig E., Le Marchand, Loic, Albanes, Demetrios, Bickeböller, Heike, Aldrich, Melinda C., Bush, William S., Tardon, Adonina, Rennert, Gad, Chen, Chu, Teare, M. Dawn, Field, John K., Kiemeney, Lambertus A., Lazarus, Philip, Haugen, Aage, Lam, Stephen, Schabath, Matthew B., Andrew, Angeline S., Shen, Hongbing, Hong, Yun-Chul, Yuan, Jian-Min, Bertazzi, Pier A., Pesatori, Angela C., Ye, Yuanqing, Diao, Nancy, Su, Li, Zhang, Ruyang, Brhane, Yonathan, Leighl, Natasha, Johansen, Jakob S., Mellemgaard, Anders, Saliba, Walid, Haiman, Christopher, Wilkens, Lynne, Fernandez-Somoano, Ana, Fernandez-Tardon, Guillermo, van der Heijden, Erik H. F. M., Kim, Jin Hee, Dai, Juncheng, Hu, Zhibin, Davies, Michael P. A., Marcus, Michael W., Brunnström, Hans, Manjer, Jonas, Melander, Olle, Muller, David C., Overvad, Kim, Trichopoulou, Antonia, Tumino, Rosario, Doherty, Jennifer, Goodman, Gary E., Cox, Angela, Taylor, Fiona, Woll, Penella, Brüske, Irene, Manz, Judith, Muley, Thomas, Risch, Angela, Rosenberger, Albert, Grankvist, Kjell, Johansson, Mikael, Shepherd, Frances, Tsao, Ming-Sound, Arnold, Susanne M., Haura, Eric B., Bolca, Ciprian, Holcatova, Ivana, Janout, Vladimir, Kontic, Milica, Lissowska, Jolanta, Mukeria, Anush, Ognjanovic, Simona, Orlowski, Tadeusz M., Scelo, Ghislaine, Swiatkowska, Beata, Zaridze, David, Bakke, Per, Skaug, Vidar, Zienolddiny, Shanbeh, Duell, Eric J., Butler, Lesley M., Koh, Woon-Puay, Gao, Yu-Tang, Houlston, Richard, McLaughlin, John, Stevens, Victoria, Nickle, David C., Obeidat, Ma’en, Timens, Wim, Zhu, Bin, Song, Lei, Artigas, María Soler, Tobin, Martin D., Wain, Louise V., Gu, Fangyi, Byun, Jinyoung, Kamal, Ahsan, Zhu, Dakai, Tyndale, Rachel F., Wei, Wei-Qi, Chanock, Stephen, Brennan, Paul, Amos, Christopher I.“…The KEGG neuroactive ligand receptor interaction pathway, two Reactome pathways, and 22 Gene Ontology terms were identified and replicated to be significantly associated with lung cancer risk, with P values less than 0.05 and FDR less than 0.1. …”
Publicado 2018
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22223por Bogie, Kath M, Zhang, Guo-Qiang, Roggenkamp, Steven K, Zeng, Ningzhou, Seton, Jacinta, Tao, Shiqiang, Bloostein, Arielle L, Sun, Jiayang“…A Spinal Cord Injury Pressure Ulcer and Deep Tissue Injury Ontology (SCIPUDO) is being developed to enable robust text-mining for data extraction from free-form notes. …”
Publicado 2018
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22224por Neubert, Patrick, Weichselbaum, Andrea, Reitinger, Carmen, Schatz, Valentin, Schröder, Agnes, Ferdinand, John R., Simon, Michaela, Bär, Anna-Lorena, Brochhausen, Christoph, Gerlach, Roman G., Tomiuk, Stefan, Hammer, Karin, Wagner, Stefan, van Zandbergen, Ger, Binger, Katrina J., Müller, Dominik N., Kitada, Kento, Clatworthy, Menna R., Kurts, Christian, Titze, Jens, Abdullah, Zeinab, Jantsch, Jonathan“…Abbreviations: ACT: actins; AKT: AKT serine/threonine kinase 1; ATG2A: autophagy related 2A; ATG4C: autophagy related 4C, cysteine peptidase; ATG7: autophagy related 7; ATG12: autophagy related 12; BECN1: beclin 1; BMDM: bone marrow-derived macrophages; BNIP3: BCL2/adenovirus E1B interacting protein 3; CFU: colony forming units; CM-H(2)DCFDA: 5-(and-6)-chloromethyl-2′,7′-dichlorodihydrofluorescein diacetate, acetyl ester; CTSB: cathepsin B; CYBB: cytochrome b-245 beta chain; DAPI: 4,6-diamidino-2-phenylindole; DMOG: dimethyloxallyl glycine; DPI: diphenyleneiodonium chloride; E. coli: Escherichia coli; FDR: false discovery rate; GFP: green fluorescent protein; GSEA: gene set enrichment analysis; GO: gene ontology; HIF1A: hypoxia inducible factor 1, alpha subunit; HUGO: human genome organization; HS: high salt (+ 40 mM of NaCl to standard cell culture conditions); HSP90: heat shock 90 kDa proteins; LDH: lactate dehydrogenase; LPS: lipopolysaccharide; Lyz2/LysM: lysozyme 2; NFAT5/TonEBP: nuclear factor of activated T cells 5; MΦ: macrophages; MAP1LC3/LC3: microtubule associated protein 1 light chain 3; MFI: mean fluorescence intensity; MIC: minimum inhibitory concentration; MOI: multiplicity of infection; MTOR: mechanistic target of rapamycin kinase; NaCl: sodium chloride; NES: normalized enrichment score; n.s.: not significant; NO: nitric oxide; NOS2/iNOS: nitric oxide synthase 2, inducible; NS: normal salt; PCR: polymerase chain reaction; PGK1: phosphoglycerate kinase 1; PHOX: phagocyte oxidase; RFP: red fluorescent protein; RNA: ribonucleic acid; ROS: reactive oxygen species; sCFP3A: super cyan fluorescent protein 3A; SBFI: sodium-binding benzofuran isophthalate; SLC2A1/GLUT1: solute carrier family 2 (facilitated glucose transporter), member 1; SQSTM1/p62: sequestosome 1; ULK1: unc-51 like kinase 1; v-ATPase: vacuolar-type H(+)-ATPase; WT: wild type…”
Publicado 2019
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22225por Wang, Ya, Cheng, Tingting, Lu, Miaolong, Mu, Yun, Li, Biao, Li, Xuejun, Zhan, Xianquan“…METHODS: Tandem mass tag (TMT)-based quantitative proteomics was used to investigate differentially expressed proteins (DEPs) between FSH-positive and negative NFPAs. Gene ontology and KEGG pathway enrichment analyses were used to analyze the DEPs. …”
Publicado 2019
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22226por Paguem, Archile, Abanda, Babette, Achukwi, Mbunkah Daniel, Baskaran, Praveen, Czemmel, Stefan, Renz, Alfons, Eisenbarth, Albert“…By using only breed-specific non-synonymous variants we identified genes as genetic signatures and associated Gene Ontology (GO) terms that could explain certain cattle-breed specific phenotypes such as increased tolerance against trypanosome parasites in the Namchi breed and heat tolerance in the Kapsiki breed. …”
Publicado 2020
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22227por Sanchez, Bethany, Zhou, Xixi, Gardiner, Amy S., Herbert, Guy, Lucas, Selita, Morishita, Masako, Wagner, James G., Lewandowski, Ryan, Harkema, Jack R., Shuey, Chris, Campen, Matthew J., Zychowski, Katherine E.“…Results indicated 27 highly differentially expressed (p < 0.01) murine miRNAs, as measured in the SCIP assay. Gene ontology (GO) pathway analysis revealed notable alterations in GO enrichment related to the cytoplasm, protein binding and the cytosol, while significant KEGG pathways involved pathways in cancer, axon guidance and Wnt signaling. …”
Publicado 2020
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22228por Wang, Liqiang, Xu, Fei, Song, Zhenfeng, Han, Dan, Zhang, Jingyi, Chen, Linjun, Na, Lixin“…Pathway analysis and gene ontology analysis were applied to describe the roles of differentially expressed mRNAs. …”
Publicado 2020
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22229“…The GSEA analysis identified that kinetochore and spindle microtubules are the two main cellular components of APEX2 in GO Ontology. APEX2 was also positively associated with molecular function regulation of chromosome segregation and DNA replication. …”
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22230por Wu, Xuejiao, Huang, Jia, Yang, Zilin, Zhu, Ying, Zhang, Yongping, Wang, Jiancheng, Yao, Weiyan“…In addition, several miR-221-3p functional analyses were conducted, including Gene Ontology (GO), Kyoto Encyclopedia of Genes and Genomes (KEGG) and Protein–protein interaction (PPI) network analyses, to examine gene interactions with miR-221-3p. …”
Publicado 2020
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22231por Yi, Hong, Zhang, Wei, Cui, Zhi-Ming, Cui, Sheng-Yu, Fan, Jian-Bo, Zhu, Xin-Hui, Liu, Wei“…Kyoto encyclopedia of genes and genomes (KEGG) pathway as well as gene ontology (GO) were further conducted through Metascape online tool. …”
Publicado 2020
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22232por Koh, Kyungmin, Park, Mira, Bae, Eun Soo, Duong, Van-An, Park, Jong-Moon, Lee, Hookeun, Lew, Helen“…Differentially expressed proteins (DEPs) were detected by label-free quantification, and the interactions of the proteins were examined through signal transduction pathway and gene ontology analysis. RESULT: We observed that exosome could significantly recover proliferation damaged by CoCl(2) treatment. …”
Publicado 2020
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22233por Zheng, Wen-jiang, Yan, Qian, Ni, Yong-shi, Zhan, Shao-feng, Yang, Liu-liu, Zhuang, Hong-fa, Liu, Xiao-hong, Jiang, Yong“…We used the ClueGO and CluePedia plugins in Cytoscape to conduct gene ontology (GO) biological process (BP) analysis and Kyoto Encyclopedia of Genes and Genomes (KEGG) signaling pathway enrichment analysis of XBJ’s effector targets. …”
Publicado 2020
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22234por Valle, Alejandra, Leiro, José Manuel, Pereiro, Patricia, Figueras, Antonio, Novoa, Beatriz, Dirks, Ron P. H., Lamas, Jesús“…Numerous genes were differentially expressed (DE) in P. dicentrarchi, relative to their expression in control ciliates (0 hpi): 407 (369 were up-regulated) at 1 hpi, 769 (415 were up-regulated) at 2 hpi and 507 (119 were up-regulated) at 4 hpi. Gene ontology (GO) analysis of the DE genes showed that the most representative categories of biological processes affected at 1, 2 and 4 hpi were biosynthetic processes, catabolic processes, biogenesis, proteolysis and transmembrane transport. …”
Publicado 2020
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22235por Alisoltani, Arghavan, Manhanzva, Monalisa T., Potgieter, Matthys, Balle, Christina, Bell, Liam, Ross, Elizabeth, Iranzadeh, Arash, du Plessis, Michelle, Radzey, Nina, McDonald, Zac, Calder, Bridget, Allali, Imane, Mulder, Nicola, Dabee, Smritee, Barnabas, Shaun, Gamieldien, Hoyam, Godzik, Adam, Blackburn, Jonathan M., Tabb, David L., Bekker, Linda-Gail, Jaspan, Heather B., Passmore, Jo-Ann S., Masson, Lindi“…Bacterial protein functional annotations (gene ontology) predicted inflammatory cytokine profiles more accurately than bacterial relative abundance determined by 16S rRNA gene sequence analysis, as well as functional predictions based on 16S rRNA gene sequence data (p < 0.0001). …”
Publicado 2020
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22236“…The top 20 down-regulated DE-exo-miRs were let-7 family, miR-221/222 family, miR-619-5p, miR-6780a-5p, miR-641, miR-200a-5p, miR-581, miR-605-3p, miR-548ar-3p, miR-135a-3p, miR-451b, miR-509-3-5p, miR-4664-3p and miR-224-5p. Gene Ontology (GO) and Kyoto Encyclopedia of Genes and Genomes (KEGG) analyses were subsequently implemented to identify the top 10 DE-exo-miRs related specific target genes and signaling pathways. …”
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22237por Kumar, Namit, Golhar, Ryan, Sharma, Kriti Sen, Holloway, James L., Sarangi, Srikant, Neuhaus, Isaac, Walsh, Alice M., Pitluk, Zachary W.“…Cells can be selected using individual metadata tags, more complex hierarchical ontology filtering, and gene expression threshold ranges, including co-expression of multiple genes. …”
Publicado 2021
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22238“…Among these DEGs, 71 tissue/organ-specific expressed genes were recognized. Gene Ontology (GO) and Kyoto Encyclopedia of Genes and Genomes (KEGG) enrichment analysis indicated that DEGs are mostly enriched in immune response, immune-related biological process, immune system, and cytokine signal pathways. …”
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22239por Anand, Deepti, Al Saai, Salma, Shrestha, Sanjaya K., Barnum, Carrie E., Chuma, Shinichiro, Lachke, Salil A.“…Majority of these targets were also altered in other gene-specific perturbation mouse models (e.g., Brg1, E2f1/E2f2/E2f3, Foxe3, Hsf4, Klf4, Mafg/Mafk, Notch) of lens defects/cataract, suggesting their importance to lens biology. Gene ontology (GO) provided further insight into their relevance to lens pathology. …”
Publicado 2021
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22240por Xu, Jiawen, Zeng, Yi, Si, Haibo, Liu, Yuan, Li, Mingyang, Zeng, Junfeng, Shen, Bin“…GSEA of TWAS identified 51 gene ontology (GO) terms for hand OA, for example, protein binding (P = 0.0003) and cytosol (P = 0.0020). …”
Publicado 2021
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