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  1. 23061
    “…Here we report a proteomics analysis of PDAC tumor and adjacent tissues by shotgun proteomics followed by label-free quantification, and in total, 3031 and 3306 proteins were identified in three pairs of PDAC tumor and adjacent tissues, respectively; 40 of them were differentially expressed for at least three-fold in PDAC tumor tissues. Ontological and interaction network analysis highlighted the dysregulation of a set of four proteins in the carboxypeptidase family: carboxypeptidase A1 (CPA1), A2 (CPA2), B1 (CPB1), and chymotrypsin C (CTRC). …”
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    Label-Free Quantitative Proteomics Unravels Carboxypeptidases as the Novel Biomarker in Pancreatic Ductal Adenocarcinoma
  2. 23062
    “…Despite ASD susceptibility genes belonging to different gene ontologies, isogenic stem cell resources can reveal common functional phenotypes, such as reduced functional connectivity.…”
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    Complete Disruption of Autism-Susceptibility Genes by Gene Editing Predominantly Reduces Functional Connectivity of Isogenic Human Neurons
  3. 23063
    “…Transcriptome microarray data from four GEO datasets (GEO: GSE7670, GSE10072, GSE68465, and GSE43458) were jointly analyzed for differentially expressed genes (DEGs). Ontologic analysis showed that most of the upregulated DEGs enriched in collagen catabolic and fibril organization processes were regulated by matrix metalloproteinases (MMPs). …”
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    Matrix Metalloproteinase 11 Is a Potential Therapeutic Target in Lung Adenocarcinoma
  4. 23064
    por Pickersgill, Martyn
    Publicado 2019
    “…Ultimately, the article aims to add empirical depth to current understandings about the epistemological and ontological politics of contemporary (US) psychiatry and to contribute to science and technology studies (STS) debates about “the new” in technoscience. …”
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    Psychiatry and the Sociology of Novelty: Negotiating the US National Institute of Mental Health “Research Domain Criteria” (RDoC)
  5. 23065
    “…The symbiotic and apo-symbiotic samples were segregated into two separate groups with several different enriched gene ontologies. Our findings suggest that the presence of endosymbionts has a greater negative impact on the host than the environmental temperature conditions experienced by the holobiont. …”
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    The Algal Symbiont Modifies the Transcriptome of the Scleractinian Coral Euphyllia paradivisa during Heat Stress
  6. 23066
    “…Correlation with various histopathological features also identified the association with the distinct gene ontological pathways. Deconvolution analysis of the RNA sequencing data set indicated a significant increase in monocytes, fibroblasts, and myofibroblasts in advanced DN kidneys. …”
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    Comparison of Kidney Transcriptomic Profiles of Early and Advanced Diabetic Nephropathy Reveals Potential New Mechanisms for Disease Progression
  7. 23067
    “…Additionally, we investigated the gene ontologies (GOs) and genetic features. RESULTS: Compared to the Berkshire and Yorkshire pigs, the JNP had lower genetic diversity in terms of linkage disequilibrium decays. …”
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    Genome-wide scans for detecting the selection signature of the Jeju-island native pig in Korea
  8. 23068
    “…MPD houses rigorously curated per-animal data with detailed protocols. Public ontologies and controlled vocabularies are used for annotation. …”
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    Mouse Phenome Database: a data repository and analysis suite for curated primary mouse phenotype data
  9. 23069
    por Gourlay, Lesley
    Publicado 2020
    “…I speculate on how the ontological nature of the university itself has been fundamentally altered by the closure of the campus and lockdown, proposing that the site of the university is now radically dispersed across these sequestered bodies. …”
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    Quarantined, Sequestered, Closed: Theorising Academic Bodies Under Covid-19 Lockdown
  10. 23070
    por Torres, Camilo, Verschoor, Gerard
    Publicado 2020
    “…We conclude by arguing for the need to re-imagine environmental governance in ways that more closely engage with what we call pluriversal governance: a form of (environmental) governance that does ontological justice to those involved in the environmental conflict – including, crucially, Indigenous people.…”
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    Re-imagining environmental governance: Gold dredge mining vs Territorial Health in the Colombian Amazon
  11. 23071
    por Stanley, Phiona
    Publicado 2021
    “…This paper critically examines epistemological, ontological, and axiological tensions of activism in three related contexts. …”
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    Problematizing “Activism”: Medical Volunteer Tourism in Central America, Local Resistance, and Academic Activism
  12. 23072
    “…Biofilms containing Streptococcus gordonii, Fusobacterium nucleatum, Porphyromonas gingivalis, and Candida albicans were established from ontological analysis. Biofilms were optimized in different media and atmospheric conditions, prior to quantification and imaging, and subsequently treated with chlorhexidine, EDTA, and chitosan. …”
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    Filling the Void: An Optimized Polymicrobial Interkingdom Biofilm Model for Assessing Novel Antimicrobial Agents in Endodontic Infection
  13. 23073
    “…Instead, posthumanism is but one form of biodigitalism that mediates the biohumanities and the digital humanities, no longer preoccupied with the tradition of the subject, but with the constellation of forces shaping the future of human ontologies. This heralds a new biopolitics which brings the philosophy of race, class, gender, and intelligence, into a compelling dialog with genomics and information.…”
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    Biodigital Philosophy, Technological Convergence, and Postdigital Knowledge Ecologies
  14. 23074
    “…We review and discuss emerging applications of statistical and machine learning techniques in human microbiome studies and introduce the COST Action CA18131 “ML4Microbiome” that brings together microbiome researchers and machine learning experts to address current challenges such as standardization of analysis pipelines for reproducibility of data analysis results, benchmarking, improvement, or development of existing and new tools and ontologies.…”
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    Statistical and Machine Learning Techniques in Human Microbiome Studies: Contemporary Challenges and Solutions
  15. 23075
    “…[Image: see text] In this paper, we develop a knowledge graph-based framework for the automated calibration of combustion reaction mechanisms and demonstrate its effectiveness on a case study of poly(oxymethylene)dimethyl ether (PODE(n), where n = 3) oxidation. We develop an ontological representation for combustion experiments, OntoChemExp, that allows for the semantic enrichment of experiments within the J-Park simulator (JPS, theworldavatar.com), an existing cross-domain knowledge graph. …”
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    Automated Calibration of a Poly(oxymethylene) Dimethyl Ether Oxidation Mechanism Using the Knowledge Graph Technology
  16. 23076
    “…We observed multiple transcriptome changes and discuss pathways and ontologies particularly relevant to Alzheimer disease and Down syndrome. …”
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    Transcriptome and metabolome analysis of crGART, a novel cell model of de novo purine synthesis deficiency: Alterations in CD36 expression and activity
  17. 23077
    “…In both cases, HN serves as a myth to justify the ontological premise of participants that the world is fair and to counteract the cognitive dissonance generated by the perception of a gender-unequal system (in the case of a woman) or by the perception of a gender-equal system that can threaten gender privileges (in the case of a man).…”
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    Heteronormativity and the Justification of Gender Hierarchy: Investigating the Archival Data From 16 European Countries
  18. 23078
    “…A biomimetic, flexible, multimodal sole sensor (FMSS) designed for legged robots to identify the ontological status and ground information, such as reaction force mapping, contact situation, terrain, and texture information, to achieve agile maneuvers was innovatively presented in this paper. …”
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    A Flexible Multimodal Sole Sensor for Legged Robot Sensing Complex Ground Information during Locomotion
  19. 23079
    por Pischetola, Magda
    Publicado 2021
    “…It aims at generating imaginative pedagogies through the use of technology while also nurturing ontological aspects of the teaching profession. The paper presents and discusses data from the first iteration, which included co-designed processes of prototype content development and a mini-trial with seven course participants. …”
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    Teaching Novice Teachers to Enhance Learning in the Hybrid University
  20. 23080
    por Sætra, Henrik Skaug
    Publicado 2021
    “…However, I argue that relationalism is, quite to the contrary, a form of neo-anthropocentrism that recenters human beings and their unique ontological properties, perceptions, and values. I do so by raising three objections: 1) relationalism centers human values and perspectives, 2) it is indirectly a type of properties-based approach, and 3) edge cases reveal potentially absurd implications in practice.…”
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    Challenging the Neo-Anthropocentric Relational Approach to Robot Rights
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