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23141por Negro, Alessandro, Montagna, Fabio, Teng, Michael N., Neal, Tempestt, Thomas, Sylvia, King, Sayde, Khan, Ridita“…Specifically, we demonstrate how to extract time-bounded key concepts, also leveraging existing ontologies, from evolving scholarly articles to create a single temporal connected source of truth specifically related to COVID-19. …”
Publicado 2023
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23142por de Kanter, Anne-Floor J., Jongsma, Karin R., Bouten, Carlijn V. C., Bredenoord, Annelien L.“…As such, they manifest the ontological entanglement of body and technology. In our ethical analysis, we argue this is ethically significant in at least two ways: It exacerbates the irreversibility of the implantation procedure, and it might affect the embodied experience of the implant recipient. …”
Publicado 2023
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23143“…It combines gene expression information with a network structure derived from gene annotations (gene ontologies) or expression profile correlations. Using both simulated and real data we find that the algorithm offers an improved ranking of genes compared to pure expression change rankings. …”
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23144por Rebholz-Schuhman, Dietrich, Cameron, Graham, Clark, Dominic, van Mulligen, Erik, Coatrieux, Jean-Louis, Del Hoyo Barbolla, Eva, Martin-Sanchez, Fernando, Milanesi, Luciano, Porro, Ivan, Beltrame, Francesco, Tollis, Ioannis, Van der Lei, Johan“…We identified emerging topics that were equally important to bioinformatics and medical informatics in recent years such as microarray experiments, ontologies, open source, text mining and support vector machines. …”
Publicado 2007
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23145por Hellsten, Uffe, Khokha, Mustafa K, Grammer, Timothy C, Harland, Richard M, Richardson, Paul, Rokhsar, Daniel S“…We find no significant difference in gene content in the duplicated set, versus the single-copy set based on molecular and biological function ontologies. CONCLUSION: These results support a scenario in which duplicate genes are retained through a process of subfunctionalization and/or relaxation of constraint on both copies of an ancestral gene.…”
Publicado 2007
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23146“…A comparison with existing tools that use GO terms suggests that mining PubMed abstracts can reveal additional biological insight that may not be possible by mining pre-defined ontologies alone.…”
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23147por Du, Rose, Tantisira, Kelan, Carey, Vincent, Bhattacharya, Soumyaroop, Metje, Stephanie, Kho, Alvin T, Klanderman, Barbara J, Gaedigk, Roger, Lazarus, Ross, Mariani, Thomas J, Leeder, J Steven, Weiss, Scott T“…CONCLUSION: We conclude that while the comparability of the platforms at the single gene level may be increased by increasing sample size, they are highly comparable ontologically even for subtle differences in a relatively small sample size. …”
Publicado 2009
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23148por Hu, Yao Fei, Gourab, Krishnaj, Wells, Clive, Clewes, Oliver, Schmit, Brian D., Sieber-Blum, Maya“…EPI-NCSC are uniquely qualified for cell-based therapy in spinal cord injury, as neural crest cells and neural tube stem cells share a higher order stem cell and are thus ontologically closely related.…”
Publicado 2010
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23149por Maqungo, Monique, Kaur, Mandeep, Kwofie, Samuel K., Radovanovic, Aleksandar, Schaefer, Ulf, Schmeier, Sebastian, Oppon, Ekow, Christoffels, Alan, Bajic, Vladimir B.“…DDPC is distinctive from other databases in that (i) it provides pre-compiled biomedical text-mining information on PC, which otherwise require tedious computational analyses, (ii) it integrates data on molecular interactions, pathways, gene ontologies, gene regulation at molecular level, predicted transcription factor binding sites on promoters of PC implicated genes and transcription factors that correspond to these binding sites and (iii) it contains DrugBank data on drugs associated with PC. …”
Publicado 2011
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23150“…We begin from an existential analysis of depression constituting the human condition and then shift to analysis of biological data confirming, according to our judgment, its original (ontological) structure. In this way philosophy is involved at the anthropological level, in as much as it detects the underlying meanings of depression in the original biological-cultural horizon of human life. …”
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23151por Willighagen, Egon L, Alvarsson, Jonathan, Andersson, Annsofie, Eklund, Martin, Lampa, Samuel, Lapins, Maris, Spjuth, Ola, Wikberg, Jarl ES“…BACKGROUND: Semantic web technologies are finding their way into the life sciences. Ontologies and semantic markup have already been used for more than a decade in molecular sciences, but have not found widespread use yet. …”
Publicado 2011
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23152“…This study provides an extensive set of functional transcriptomic annotations that will assist researchers in uncovering the precise mechanisms underlying the developmental ontologies of higher eukaryotes.…”
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23153“…Our RDF model and resulting dataset make extensive use of existing ontologies and semantic enrichment services. We expose our model, services, prototype, and datasets at http://biotea.idiginfo.org/ CONCLUSIONS: The semantic processing of biomedical literature presented in this paper embeds documents within the Web of Data and facilitates the execution of concept-based queries against the entire digital library. …”
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23154“…The system incorporates a broad array of approaches proposed to benefit tagging, including the use of Unified Medical Language System (UMLS)- and Open Biomedical Ontologies (OBO)-based lexical resources, word representations induced from unlabeled text, statistical truecasing and non-local features. …”
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23155por Gour, Pratibha, Garg, Priyanka, Jain, Rashmi, Joseph, Shaji V., Tyagi, Akhilesh K., Raghuvanshi, Saurabh“…Using these models data of individual experiments have been digitized with the help of universal ontologies. Currently, the database has data for over 1800 rice proteins curated from >4000 different experiments of over 400 research articles. …”
Publicado 2014
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23156por Monaco, Marcela K., Stein, Joshua, Naithani, Sushma, Wei, Sharon, Dharmawardhana, Palitha, Kumari, Sunita, Amarasinghe, Vindhya, Youens-Clark, Ken, Thomason, James, Preece, Justin, Pasternak, Shiran, Olson, Andrew, Jiao, Yinping, Lu, Zhenyuan, Bolser, Dan, Kerhornou, Arnaud, Staines, Dan, Walts, Brandon, Wu, Guanming, D’Eustachio, Peter, Haw, Robin, Croft, David, Kersey, Paul J., Stein, Lincoln, Jaiswal, Pankaj, Ware, Doreen“…Its strength derives from the application of a phylogenetic framework for genome comparison and the use of ontologies to integrate structural and functional annotation data. …”
Publicado 2014
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23157por Narytnyk, Alla, Verdon, Bernard, Loughney, Andrew, Sweeney, Michele, Clewes, Oliver, Taggart, Michael J., Sieber-Blum, Maya“…This novel development is an important first step towards the establishment of fully functional dopaminergic neurons from an ontologically relevant stem cell type, hEPI-NCSC. ELECTRONIC SUPPLEMENTARY MATERIAL: The online version of this article (doi:10.1007/s12015-013-9493-9) contains supplementary material, which is available to authorized users.…”
Publicado 2014
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23158“…The assembly formed into 22,652 isotigs, distributed by GO analysis across 55 categories in the three ontologies, ‘molecular function’, ‘cellular component’, and ‘biological processes’. …”
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23159“…Significance analysis of microarrays (SAM) indicated that 808 genes were differentially transcribed between the rearing environments and a total of 184 gene ontological (GO) terms were over- or under-represented in this gene list, several associated with mitosis/cell cycle and muscle and heart development. …”
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23160por Kriventseva, Evgenia V., Tegenfeldt, Fredrik, Petty, Tom J., Waterhouse, Robert M., Simão, Felipe A., Pozdnyakov, Igor A., Ioannidis, Panagiotis, Zdobnov, Evgeny M.“…The text searches allow use of complex logic with various identifiers of genes, proteins, domains, ontologies or annotation keywords and phrases. Gene copy-number profiles can also be queried. …”
Publicado 2014
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