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23181por Westbrook, Anthony, Ramsdell, Jordan, Schuelke, Taruna, Normington, Louisa, Bergeron, R Daniel, Thomas, W Kelley, MacManes, Matthew D“…Using simulated reads, PALADIN consistently outperformed the popular DNA read mappers BWA and NovoAlign in detected proteins, percentage of reads mapped and ontological similarity. We also compared PALADIN against four existing protein alignment tools: BLASTX, RAPSearch2, DIAMOND and Lambda, using empirically obtained reads. …”
Publicado 2017
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23182por Racine, Eric“…This paper contextualizes ontological and epistemological debates about free will, describes a scientifically-informed and instrumentalist account of the concept of free will and voluntary action consistent with recent research in cognitive science, and discusses its implications for research (e.g., theoretical assumptions of research paradigms, interdisciplinary research) and practice (e.g., impact on self-image and social behavior).…”
Publicado 2017
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23183“…Nano-lazar provides a flexible and reproducible framework for downloading data and ontologies from the open eNanoMapper infrastructure, developing and validating nanoparticle read across models, open-source code and a free graphical interface for nanoparticle read-across predictions. …”
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23184por Shi, Jinlong, Chen, Xia, Li, Haiying, Wu, Youjia, Wang, Shouyan, Shi, Wei, Chen, Jian, Ni, Yaohui“…We then performed bioinformatics analyses, including gene ontological (GO) and pathway analysis and co-expression network analysis to screen for novel key pathways and genes involved in the pathology of OGD/R. …”
Publicado 2017
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23185“…These datasets include published data from genome-wide RNAi and CRISPR screens, interactome proteomics and phosphoproteomics screens, cancer mutation databases, low-throughput studies of major cell signaling mediators, such as kinases, E3 ubiquitin ligases and phosphatases, and gene ontological information. Moreover, CrossCheck includes a novel database of predicted protein kinase substrates, which was developed using proteome-wide consensus motif searches. …”
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23186por Rossi, Fabrizio, Molnar, Cristina, Hashiyama, Kazuya, Heinen, Jan P., Pampalona, Judit, Llamazares, Salud, Reina, José, Hashiyama, Tomomi, Rai, Madhulika, Pollarolo, Giulia, Fernández-Hernández, Ismael, Gonzalez, Cayetano“…We have identified 131 targets, which belong to a wide range of gene ontologies. Most of these target genes are not significantly overexpressed in mbt tumours hence showing that, rather counterintuitively, tumour-linked overexpression is not a good predictor of functional requirement. …”
Publicado 2017
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23187por Hill, Sophie“…These possible threshold concepts involve changes in both conceptual and ontological knowledge, integrating into the persona of the individual. …”
Publicado 2016
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23188por Bogue, Molly A, Grubb, Stephen C, Walton, David O, Philip, Vivek M, Kolishovski, Georgi, Stearns, Tim, Dunn, Matthew H, Skelly, Daniel A, Kadakkuzha, Beena, TeHennepe, Gregg, Kunde-Ramamoorthy, Govindarajan, Chesler, Elissa J“…MPD provides rigorous curation of experimental data and supporting documentation using relevant ontologies and controlled vocabularies. Most data in MPD are from inbreds and other reproducible strains such that the data are cumulative over time and across laboratories. …”
Publicado 2018
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23189“…This essay describes the procedures used to set up a data infrastructure (e.g., data access and exchange, definition of the minimum common wealth of data required, and the development of the relational logic data model) and, the methods to produce trustworthy healthcare performance measurements (e.g., ontologies standardisation and quality assurance analysis). …”
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23190por Lochmüller, Hanns, Torrent i Farnell, Josep, Le Cam, Yann, Jonker, Anneliene H, Lau, Lilian PL, Baynam, Gareth, Kaufmann, Petra, Dawkins, Hugh JS, Lasko, Paul, Austin, Christopher P, Boycott, Kym M“…The Policies and Guidelines provide guidance on ontologies, diagnostics, biomarkers, patient registries, biobanks, natural history, therapeutics, models, publication, intellectual property, and communication. …”
Publicado 2017
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23191por Mitchell, Audra“…This is a profound category mistake: extinction needs to be understood not in the ontic terms of life and death, but rather in the ontological context of be(com)ing and negation. Drawing on the work of theorists of the ‘inhuman’ such as Quentin Meillassoux, Claire Colebrook, Ray Brassier, Jean-Francois Lyotard and Nigel Clark, this article provides a pathway for thinking beyond existing horizons of survival and imagines a profound transformation of International Relations. …”
Publicado 2016
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23192por Cui, Licong, Zhu, Wei, Tao, Shiqiang, Case, James T, Bodenreider, Olivier, Zhang, Guo-Qiang“…Objective: Quality assurance of large ontological systems such as SNOMED CT is an indispensable part of the terminology management lifecycle. …”
Publicado 2017
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23193por Falk, Taylor, Herndon, Nic, Grau, Emily, Buehler, Sean, Richter, Peter, Zaman, Sumaira, Baker, Eliza M, Ramnath, Risharde, Ficklin, Stephen, Staton, Margaret, Feltus, Frank A, Jung, Sook, Main, Doreen, Wegrzyn, Jill L“…Recent development in TreeGenes has focused on coordinating information for georeferenced accessions, including metadata acquisition and ontological frameworks, to improve integration across studies combining genetic, phenotypic and environmental data. …”
Publicado 2018
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23194“…Legal arguments vary a lot around the world, and seeking ontological arguments for privacy does not necessarily lead to a universal acclaim of safeguarding the learner meeting the new data-driven practices in education. …”
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23195por Katayama, Toshiaki, Kawashima, Shuichi, Okamoto, Shinobu, Moriya, Yuki, Chiba, Hirokazu, Naito, Yuki, Fujisawa, Takatomo, Mori, Hiroshi, Takagi, Toshihisa“…TogoGenome provides a semantic-faceted search system by gene functional annotation, taxonomy, phenotypes and environment based on the relevant ontologies. TogoGenome also serves as an interface to conduct semantic comparative genomics by which a user can observe pan-organism or organism-specific genes based on the functional aspect of gene annotations and the combinations of organisms from different taxa. …”
Publicado 2019
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23196por Ma, Jie, Chen, Tao, Wu, Songfeng, Yang, Chunyuan, Bai, Mingze, Shu, Kunxian, Li, Kenli, Zhang, Guoqing, Jin, Zhong, He, Fuchu, Hermjakob, Henning, Zhu, Yunping“…Also, it deploys extensive controlled vocabularies and ontologies to annotate proteomics datasets. Users can use a GUI to provide and access data through a fast Aspera-based transfer tool. iProX is a full member of the PX consortium; all released datasets are freely accessible to the public. iProX is based on a high availability architecture and has been deployed as part of the proteomics infrastructure of China, ensuring long-term and stable resource support. iProX will facilitate worldwide data analysis and sharing of proteomics experiments.…”
Publicado 2019
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23197“…Developing an Internet of Food, as a precompetitive platform on which business models can be built, much like the internet as we currently know it, will require agreed vocabularies and ontologies to be able to reason and compute across the vast amounts of data that are becoming available. …”
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23198por Kamdar, Maulik R., Fernández, Javier D., Polleres, Axel, Tudorache, Tania, Musen, Mark A.“…The biomedical research community has been one of the earliest adopters of these technologies and principles to publish data and knowledge on the Web as linked graphs and ontologies, hence creating the Life Sciences Linked Open Data (LSLOD) cloud. …”
Publicado 2019
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23199por Singer, Wolf“…A natural consequence of these extended perceptions is a dualist classification of observables into material and immaterial phenomena nurturing the concept of ontological substance dualism. It is argued that perceptions shaped by socio-cultural priors lead to the construction of a self-model that has both a material and an immaterial dimension. …”
Publicado 2019
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23200por Arabfard, Masoud, Ohadi, Mina, Rezaei Tabar, Vahid, Delbari, Ahmad, Kavousi, Kaveh“…The identified candidate genes are associated with pathways, ontologies, and diseases that are linked to aging, such as cancer and diabetes. …”
Publicado 2019
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