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  1. 23461
    “…Equally, between SAT-O and SAT-N, the expression of 20 miRNAs differed significantly, between SAT-PO and SAT-N the expression of 79 miRNAs differed significantly, and between SAT-PO and SAT-O, the expression of 61 miRNAs differed significantly. Ontological analyses disclosed several molecular pathways regulated by these miRNAs in adipose tissue. …”
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    NGS Reveals Molecular Pathways Affected by Obesity and Weight Loss-Related Changes in miRNA Levels in Adipose Tissue
  2. 23462
    “…While authors are in the best position to curate their own data, they face a steep learning curve to ensure that appropriate referential tags, metadata, and ontologies are applied correctly to their observations, a task sometimes considered beyond the scope of their research and other numerous responsibilities. …”
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    Micropublication: incentivizing community curation and placing unpublished data into the public domain
  3. 23463
    “…Outlier analyses indicated 1,184 loci putatively under selection (ca. 15% of the total) related to 194 different Gene Ontologies (GOs); the most numerous GOs were nucleotide binding, ATP binding, metal-ion binding and nucleic-acid binding. …”
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    Loci under selection and markers associated with host plant and host-related strains shape the genetic structure of Brazilian populations of Spodoptera frugiperda (Lepidoptera, Noctuidae)
  4. 23464
    “…People with T2DM will be identified from the dataset using a well-established ontological process. Read and other clinical codes will be used to identify people prescribed liraglutide and those at high cardiovascular risk. …”
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    Does Real World Use of Liraglutide Match its Use in the LEADER Cardiovascular Outcome Trial? Study Protocol
  5. 23465
    “…EV fractions obtained with either method contained established EV markers and proteins linked to vesicle-related gene ontologies. Thus, Vn96 peptide-mediated aggregation is an advantageous, simple and rapid approach for EV isolation from small biological samples, enabling high-throughput analysis in a biomarker discovery setting.…”
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    Peptide-mediated ‘miniprep’ isolation of extracellular vesicles is suitable for high-throughput proteomics
  6. 23466
    “…CONCLUSION: Our methodology can be applied to the entirety of medical 3D printing literature to obtain a complete, validated, and objective set of recommended and synonymous definitions to aid expert bodies in building ontological consensus. ELECTRONIC SUPPLEMENTARY MATERIAL: The online version of this article (doi:10.1186/s41205-017-0012-5) contains supplementary material, which is available to authorized users.…”
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    Medical 3D printing: methods to standardize terminology and report trends
  7. 23467
    por Wamsler, Christine
    Publicado 2018
    “…The paper concludes that mindfulness has the potential to facilitate adaptation at all scales (through cognitive, managerial, structural, ontological, and epistemological change processes) and should, therefore, become a core element in climate and associated sustainability research. …”
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    Mind the gap: The role of mindfulness in adapting to increasing risk and climate change
  8. 23468
    “…To solve this problem, we created Spfy, a platform that rapidly performs the common reference laboratory tests, uses a graph database to store and retrieve the results from the computational workflows and links data to individual genomes using standardized ontologies. The Spfy platform facilitates rapid phenotype identification, as well as the efficient storage and downstream comparative analysis of tens of thousands of genome sequences. …”
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    Spfy: an integrated graph database for real-time prediction of bacterial phenotypes and downstream comparative analyses
  9. 23469
    “…With RNA-seq, we found that cells of the PBG group were differentiated toward retinal lineage and may be related to the glutamate signaling pathway. Further ontological analysis and the gene network analysis showed that the differentially expressed genes between cells of the PBG group and the control group were mainly associated with neuronal differentiation, neuronal maturation, and more specifically, retinal differentiation and maturation. …”
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    Polybenzyl Glutamate Biocompatible Scaffold Promotes the Efficiency of Retinal Differentiation toward Retinal Ganglion Cell Lineage from Human-Induced Pluripotent Stem Cells
  10. 23470
    “…RESULTS: Testosterone significantly influenced the expression of numerous immune-related genes, ontologies, and Kyoto Encyclopedia of Genes and Genomes (KEGG) pathways in lacrimal glands of MRL/lpr and NOD mice. …”
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    Testosterone Influence on Gene Expression in Lacrimal Glands of Mouse Models of Sjögren Syndrome
  11. 23471
    “…Transcriptomic changes in response to glucocorticoid exposure were similar in ASM derived from donors with fatal asthma and donors without asthma, with enriched ontological pathways that included cytokine- and chemokine-related categories. …”
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    Airway Smooth Muscle–Specific Transcriptomic Signatures of Glucocorticoid Exposure
  12. 23472
    “…Aptamer-based proteomic profiling revealed alterations in post-TAVR serum composition, and ontological analysis identified inflammatory macrophage factors implicated in myofibroblast activation and deactivation. …”
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    Transcatheter aortic valve replacements alter circulating serum factors to mediate myofibroblast deactivation
  13. 23473
    “…These results show some similarities with a previous proteomics study of the maternal medial prefrontal cortex and genomics approaches applied to the preoptic area. Gene ontological analysis suggested that most altered proteins are involved in glucose metabolism and neuroplasticity. …”
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    Proteomic Analysis of the Maternal Preoptic Area in Rats
  14. 23474
    “…After reads preprocessing, mapping, variant calling, and annotation, a filtering strategy based on allelic frequency, recessive inheritance, and phenotypic ontologies has been applied. A fetal magnetic resonance imaging (MRI) at 18 weeks of gestation has been performed. …”
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    Prenatal whole exome sequencing detects a new homozygous fukutin (FKTN) mutation in a fetus with an ultrasound suspicion of familial Dandy–Walker malformation
  15. 23475
    “…The paper's discussion contributes to ongoing research across the social sciences on the ontological politics of (good) food, and the key role of narratives in constructing and contesting visions of ‘better’ food futures.…”
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    Framing the future of food: The contested promises of alternative proteins
  16. 23476
    “…These features consisted of the following: common data elements, data visualization and analysis tools, and biomedical ontologies for data integration. Stem cell bioinformatics is a quickly evolving field that generates a growing number of heterogeneous data sets. …”
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    Informatics Approaches for Harmonized Intelligent Integration of Stem Cell Research
  17. 23477
    “…Here, we propose a novel method of prioritization of a GWAS by exploiting gene‐level knowledge (e.g., annotations to pathways and ontologies) and show that it further improves power. …”
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    A framework for pathway knowledge driven prioritization in genome‐wide association studies
  18. 23478
    “…The biological pathways can be identified performing posterior analysis of these signatures established via cross-validation holdouts and plugging the set of most frequently sampled genes into different ontological platforms. That way, the effect of helper genes, whose presence might be due to the high degree of under determinacy of these experiments and data noise, is reduced. …”
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    Robust Sampling of Defective Pathways in Alzheimer’s Disease. Implications in Drug Repositioning
  19. 23479
    “…We characterised several common SVs in haematological cancers (AML and MDS) that were linked to the same mtDNA region, MT-ND5, using only 10 cells, indicating the power of MitoSV-seq in determining single-cancer-cell ontologies. Notably, the MT-ND5 hotspot, shared between all examined cancers and Ifnar1(−/−) dopaminergic neurons, suggests that its mutations have clinical value as disease biomarkers. …”
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    Identification of unique and shared mitochondrial DNA mutations in neurodegeneration and cancer by single-cell mitochondrial DNA structural variation sequencing (MitoSV-seq)
  20. 23480
    “…Comparing transcriptomic responses of maize (determined in an adjacent study) and teosinte lines indicated three common gene ontologies up-regulated when weed-stressed: jasmonic acid response/signaling, UDP-glucosyl and glucuronyltransferases, and quercetin glucosyltransferase (3-O and 7-O). …”
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    Teosinte (Zea mays ssp parviglumis) growth and transcriptomic response to weed stress identifies similarities and differences between varieties and with modern maize varieties
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