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  1. 23761
    “…The functional annotations and metabolic pathway enrichment analysis showed cellular localization and transmembrane transport as the top gene ontological terms. The in silico and in vitro expression analyses were conducted to validate the three candidate genes in a pleiotropic QTL on chromosome 7. …”
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    Unveiling the genetic architecture for lodging resistance in rice (Oryza sativa. L) by genome-wide association analyses
  2. 23762
    “…Furthermore, several KEGG pathways and enriched gene ontologies associated with immune system activation and the metabolic process were demonstrated by analyzing the functional enrichment of the genes that were affected. …”
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    Intra- and Interspecies RNA-Seq Based Variants in the Lactation Process of Ruminants
  3. 23763
    “…Chronic audiogenic stressors, including aging accompanying ontological diseases, cumulative noise exposure, and ototoxic drugs as well as tinnitus, activate the HPA axis and SAM directly and indirectly by the amygdala, promoting allostatic load and maladaptive neuroplasticity in the auditory system and other vulnerable brain regions, such as the hippocampus, amygdala, and medial prefrontal cortex (mPFC). …”
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    Vulnerability to chronic stress and the phenotypic heterogeneity of presbycusis with subjective tinnitus
  4. 23764
    “…Knowledge formalization through ontologies has become commonplace, triggering the subsequent development of knowledge graphs and cognitive software agents. …”
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    Knowledge Engineering in Chemistry: From Expert Systems to Agents of Creation
  5. 23765
    “…Both TEMPROT and TEMPROT+ achieved competitive results on [Formula: see text] , [Formula: see text] , AuPRC and IAuPRC metrics on Biological Process (BP), Cellular Component (CC) and Molecular Function (MF) ontologies compared to state-of-the-art models, with the main results equal to 0.581, 0.692 and 0.662 of [Formula: see text] on BP, CC and MF, respectively. …”
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    TEMPROT: protein function annotation using transformers embeddings and homology search
  6. 23766
    “…Our data show hypermethylation of CpGs within genes that cluster in gene ontologies related to myelination and axon ensheathment. …”
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    From methylation to myelination: epigenomic and transcriptomic profiling of chronic inactive demyelinated multiple sclerosis lesions
  7. 23767
    “…Understanding the relationship between withdrawal and risk-involved behavior may also have important implications for the ways that problematic drug use is conceptualized, particularly in disease models of addiction, which position risk behavior as evidence of pathology that helps to justify ontological distinctions between addicts and non-addicts. …”
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    “As safe as possible”: a qualitative study of opioid withdrawal and risk behavior among people who use illegal opioids
  8. 23768
    “…The DEG list contained 3 major ontologies: infection-related, inflammation-related, and ribosomal processing. …”
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    Acute appendicitis: transcript profiling of blood identifies promising biomarkers and potential underlying processes
  9. 23769
    “…In addition, MVLD includes recommendations for controlled semantics and ontologies. The Somatic WG is collaborating with ClinVar to evaluate MVLD use for somatic variant submissions. …”
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    Somatic cancer variant curation and harmonization through consensus minimum variant level data
  10. 23770
    “…However, further development, including incorporation of ontologies, will be necessary to improve the performance of the extraction for some character types.…”
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    Microbial phenomics information extractor (MicroPIE): a natural language processing tool for the automated acquisition of prokaryotic phenotypic characters from text sources
  11. 23771
    “…High data quality within the practice network and an ontological approach to classification resulted in a high level of data completeness in the T2DM cohort; ethnicity identification (82.1%), smoking status (99.3%), alcohol use (93.3%), glycated haemoglobin (HbA1c; 97.9%), body mass index (98.0%), blood pressure (99.4%), cholesterol (87.4%) and renal function (97.8%). …”
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    Real-world evidence studies into treatment adherence, thresholds for intervention and disparities in treatment in people with type 2 diabetes in the UK
  12. 23772
    “…Safety events were self-reported by patients and mapped to medical ontologies, resolving synonyms. Disease and symptom-related treatment indications were manually redacted. …”
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    Social media for arthritis-related comparative effectiveness and safety research and the impact of direct-to-consumer advertising
  13. 23773
    “…METHODS: We utilized a computational approach based upon emerging biomedical and biological ontologies and semantic technologies to investigate the important roles of microRNA: mRNA regulation on glucocorticoid resistance in pediatric acute lymphoblastic leukemia. …”
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    A semantics-oriented computational approach to investigate microRNA regulation on glucocorticoid resistance in pediatric acute lymphoblastic leukemia
  14. 23774
    “…Nfr2 was detected as one of the most relevant proteins in the network, participating in several multifunctional protein complexes in clusters 1, 2, 3 and 5. Ontological analysis of cluster 3 revealed several processes related to unfolded protein response (UPR) and response to endoplasmic reticulum (ER) stress. …”
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    Nuclear factor erythroid 2 – related factor 2 and its relationship with cellular response in nickel exposure: a systems biology analysis
  15. 23775
    “…The detailed transcriptome analysis revealed regulation of several cancer- and metabolism-related pathways and gene ontologies. The down-regulated pathways included, cell cycle, p53 signaling, DNA replication, sphingolipid metabolism and drug metabolism by cytochrome P450. …”
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    Transcriptomic analysis of marine endophytic fungi extract identifies highly enriched anti-fungal fractions targeting cancer pathways in HepG2 cell lines
  16. 23776
    “…Further, several GWAS candidates were regulatory genes that may participate in the regulation of stress responses, and gene ontologies related to development and morphogenesis were enriched, suggesting many of these genes influence thermal tolerance through effects on development and physiological status. …”
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    Integrating GWAS and Transcriptomics to Identify the Molecular Underpinnings of Thermal Stress Responses in Drosophila melanogaster
  17. 23777
    “…In this article, we report on an extension of holistic problem framing techniques called comprehensive success factor analysis (CSFA) that makes-sense of web-mined information reflective of both expert and general population perspectives as well as pattern-informed ontological knowledge organization structure, to yield ‘richer pictures’ of grand challenges. …”
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    Framing the Intractable: Comprehensive Success Factor Analysis for Grand Challenges
  18. 23778
    “…Metascape software was used to construct gene ontologies, metabolic pathways and protein-protein interaction networks. …”
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    Bioinformatics Analysis of the SIRT Family Members and Assessment of Their Potential Clinical Value
  19. 23779
    “…We evaluated three medical ontologies (SNOMED CT, HPO and LOINC) for their usefulness. …”
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    How to design a registry for undiagnosed patients in the framework of rare disease diagnosis: suggestions on software, data set and coding system
  20. 23780
    por Galgonek, Jakub, Vondrášek, Jiří
    Publicado 2021
    “…The Resource Description Framework (RDF), together with well-defined ontologies, significantly increases data interoperability and usability. …”
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    IDSM ChemWebRDF: SPARQLing small-molecule datasets
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