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23841Quantitative Sequencing Analysis of the Striatal Transcriptome in a Mouse Model of Alzheimer Disease“…To compare the changes in biological pathways and networks, we analyzed gene lists from each comparison term via bioinformatics tools including DAVID (Database for Annotation, Visualization, and Integrated Discovery), STRING (Search Tool for the Retrieval of Interacting Genes/Proteins), and SynGO (Synaptic Gene Ontologies). Furthermore, to assume the effect MeCP2 in AD pathological conditions may have on the transcriptome regulation, analysis of the common genes from Quant-Seq and MeCP2-ChIP-Seq was performed. …”
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23842por De Rosario, Helios, Pitarch-Corresa, Salvador, Pedrosa, Ignacio, Vidal-Pedrós, Marina, de Otto-López, Beatriz, García-Mieres, Helena, Álvarez-Rodríguez, Lydia“…The most frequent approach was based on general machine learning techniques applied to the results of relatively simple NLP methods with the support of ontologies and standard vocabularies. Although smaller in number, there has been an increasing body of studies using deep learning techniques on numerical and vectorized representations of the texts obtained with more sophisticated NLP tools. …”
Publicado 2023
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23843por Vandervalk, Ben, McCarthy, E Luke, Cruz-Toledo, José, Klein, Artjom, Baker, Christopher J O, Dumontier, Michel, Wilkinson, Mark D“…While this prototype was limited to a single knowledge domain (drug/drug interactions), the proposed architecture is generalizable, and could act as the foundation for much richer personalized-health-Web clients, while importantly providing a novel and personalizable mechanism for clinical experts to inject their expertise into the browsing experience of their patients in the form of customized semantic queries and ontologies.…”
Publicado 2013
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23844por Bujold, Mathieu, Pluye, Pierre, Légaré, France, Haggerty, Jeannie, Gore, Genevieve C, Sherif, Reem El, Poitras, Marie-Ève, Beaulieu, Marie-Claude, Beaulieu, Marie-Dominique, Bush, Paula L, Couturier, Yves, Débarges, Béatrice, Gagnon, Justin, Giguère, Anik, Grad, Roland, Granikov, Vera, Goulet, Serge, Hudon, Catherine, Kremer, Bernardo, Kröger, Edeltraut, Kudrina, Irina, Lebouché, Bertrand, Loignon, Christine, Lussier, Marie-Thérèse, Martello, Cristiano, Nguyen, Quynh, Pratt, Rebekah, Rihoux, Benoit, Rosenberg, Ellen, Samson, Isabelle, Senn, Nicolas, Li Tang, David, Tsujimoto, Masashi, Vedel, Isabelle, Ventelou, Bruno, Wensing, Michel“…ETHICS AND DISSEMINATION: This systematic review, together with the qualitative study (approved by the Centre Intégré Universitaire de Santé et Service Sociaux du Saguenay-Lac-Saint-Jean ethical committee), will produce a working taxonomy of key decisional needs (ontological contribution), to inform the subsequent user-centred design of a support tool for addressing PCCNs’ decisional needs (practical contribution). …”
Publicado 2017
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23845“…To address this, we trained organism-specific models to infer sample sex from gene expression data, and used entity normalization to map metadata cell line and drug mentions to existing ontologies. Using this method, we inferred sex labels for 450,371 human and 245,107 mouse microarray and RNA-seq samples from refine.bio. …”
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23846por McLoon, Anna L., Boeck, Max E., Bruckskotten, Marc, Keyel, Alexander C., Søgaard-Andersen, Lotte“…We then identified Interpro gene ontologies and COG annotations that are significantly up- or down-regulated during development in each species. …”
Publicado 2021
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23847“…RESULTS: Analysis of gonad methylomes revealed a total of 1284 differentially methylated loci (DML) found primarily in genes, with several genes containing multiple DML. Gene ontologies for genes containing DML were involved in development and stress response, suggesting methylation may promote gonad growth homeostasis in low pH conditions. …”
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23848por Oporia, Frederick, Nuwaha, Fred, Kibira, Simon P S, Kobusingye, Olive, Makumbi, Fredrick Edward, Nakafeero, Mary, Ssenyonga, Ronald, Isunju, John Bosco, Jagnoor, Jagnoor“…METHODS: We conducted a cross-sectional survey, grounded on etic epistemology and a positivist ontological paradigm. We interviewed 1343 boaters across 18 landing sites on Lake Albert, Uganda. …”
Publicado 2022
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23849por Campillos-Llanos, Leonardo“…Lexicons gather terms and concepts from thesauri and ontologies, and linguistic data for part-of-speech (PoS) tagging, lemmatization or natural language generation. …”
Publicado 2023
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23850por Vos, Rutger Aldo, Biserkov, Jordan Valkov, Balech, Bachir, Beard, Niall, Blissett, Matthew, Brenninkmeijer, Christian, van Dooren, Tom, Eades, David, Gosline, George, Groom, Quentin John, Hamann, Thomas D., Hettling, Hannes, Hoehndorf, Robert, Holleman, Ayco, Hovenkamp, Peter, Kelbert, Patricia, King, David, Kirkup, Don, Lammers, Youri, DeMeulemeester, Thibaut, Mietchen, Daniel, Miller, Jeremy A., Mounce, Ross, Nicolson, Nicola, Page, Rod, Pawlik, Aleksandra, Pereira, Serrano, Penev, Lyubomir, Richards, Kevin, Sautter, Guido, Shorthouse, David Peter, Tähtinen, Marko, Weiland, Claus, Williams, Alan R., Sierra, Soraya“…The participants brought expertise in processing structured data, text mining, development of ontologies, digital identification keys, geographic information systems, niche modeling, natural language processing, provenance annotation, semantic integration, taxonomic name resolution, web service interfaces, workflow tools and visualisation. …”
Publicado 2014
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23851por Chan, Lawrence WC, Liu, Ying, Chan, Tao, Law, Helen KW, Wong, SC Cesar, Yeung, Andy PH, Lo, KF, Yeung, SW, Kwok, KY, Chan, William YL, Lau, Thomas YH, Shyu, Chi-Ren“…Each report was characterized by an ontological feature vector and there were totally 6216 vector pairs. …”
Publicado 2015
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23852por Kariithi, Henry M., Boeren, Sjef, Murungi, Edwin K., Vlak, Just M., Abd-Alla, Adly M. M.“…We annotated the identified proteins into gene ontologies and mapped the up- and downregulated proteins within protein-protein interaction (PPI) networks. …”
Publicado 2016
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23853por Wong, Yick Ching, Teh, Huey Fang, Mebus, Katharina, Ooi, Tony Eng Keong, Kwong, Qi Bin, Koo, Ka Loo, Ong, Chuang Kee, Mayes, Sean, Chew, Fook Tim, Appleton, David R., Kulaveerasingam, Harikrishna“…RESULTS: A total of 3412 (2001 annotated) gene candidates were found to be significantly differentially expressed between high- and low-yielding palms at at least one of the different stages of mesocarp development evaluated. Gene Ontologies (GO) enrichment analysis identified 28 significantly enriched GO terms, including regulation of transcription, fatty acid biosynthesis and metabolic processes. …”
Publicado 2017
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23854por Llorens, C., Arcos, S. C., Robertson, L., Ramos, R., Futami, R., Soriano, B., Ciordia, S., Careche, M., González-Muñoz, M., Jiménez-Ruiz, Y., Carballeda-Sangiao, N., Moneo, I., Albar, J. P., Blaxter, M., Navas, A.“…While intermediary metabolism appeared to be typical for nematodes in the 3 evaluated taxa, their transcriptomes present strong levels of differential expression and enrichment, mainly of transcripts related to metabolic pathways and gene ontologies associated to energy metabolism and other pathways, with significant presence of excreted/secreted proteins, most of them allergens. …”
Publicado 2018
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23855por Chen, Longsheng, Xu, Minjie, Gong, Zhunan, Zonyane, Samkele, Xu, Shuwen, Makunga, Nokwanda P.“…A concentration range of 5 μg/ml to 50 μg/ml was then chosen to monitor the ontological development of cultured embryos. A liquid chromatography-mass spectrometry/mass spectrometry (LC-MS/MS) method was used to study the differences of the two experimental extracts. …”
Publicado 2018
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23856por Chouvarda, Ioanna, Maramis, Christos, Livitckaia, Kristina, Trajkovik, Vladimir, Burmaoglu, Serhat, Belani, Hrvoje, Kool, Jan, Lewandowski, Roman“…The framework is visualized as an ontological model. CONCLUSIONS: The CHIF is an initial step toward identifying methodologies to objectively measure CH impact while recognizing its multiple dimensions and scales.…”
Publicado 2019
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23857por Balic, Adam, Chintoan-Uta, Cosmin, Vohra, Prerna, Sutton, Kate M., Cassady-Cain, Robin L., Hu, Tuan, Donaldson, David S., Stevens, Mark P., Mabbott, Neil A., Hume, David A., Sang, Helen M., Vervelde, Lonneke“…The novel expression of CSF1R in birds suggests that these functional equivalents to mammalian M cells may have different ontological origins and their development and function are likely to be regulated by different growth factors.…”
Publicado 2019
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23858por Cheng, Sen, Xie, Weiyan, Miao, Yazhou, Guo, Jing, Wang, Jichao, Li, Chuzhong, Zhang, Yazhuo“…Nineteen genes that exhibited notably negative correlations between DNA methylation and gene expression levels, are involved in various gene ontologies and pathways, or played an important role in different diseases, were regarded as candidate genes. …”
Publicado 2019
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23859por Wu, Sunny Z., Roden, Daniel L., Al-Eryani, Ghamdan, Bartonicek, Nenad, Harvey, Kate, Cazet, Aurélie S., Chan, Chia-Ling, Junankar, Simon, Hui, Mun N., Millar, Ewan A., Beretov, Julia, Horvath, Lisa, Joshua, Anthony M., Stricker, Phillip, Wilmott, James S., Quek, Camelia, Long, Georgina V., Scolyer, Richard A., Yeung, Bertrand Z., Segara, Davendra, Mak, Cindy, Warrier, Sanjay, Powell, Joseph E., O’Toole, Sandra, Lim, Elgene, Swarbrick, Alexander“…We performed detailed analyses between cells from each condition to assess the effects of cryopreservation on cellular heterogeneity, cell quality, clustering and the identification of gene ontologies. In addition, we performed single-cell immunophenotyping using CITE-Seq on a single breast cancer sample cryopreserved as solid tissue fragments. …”
Publicado 2021
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23860por Weaver, Daniel B., Cantarel, Brandi L., Elsik, Christine G., Boncristiani, Dawn L., Evans, Jay D.“…By mapping gene expression results against current ontologies and other studies, we describe the impacts of mite parasitism, as well as viruses on bee health against two genetic backgrounds. …”
Publicado 2021
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