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762“…One such reference is the Gene Ontology (GO). A number of groups have suggested that the semantic similarity of the GO annotations of genes can serve as a proxy for functional relatedness. …”
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763“…The display of ontological information has become a crucial factor over the last decade in systems biology. …”
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764Protein secretion systems in bacterial-host associations, and their description in the Gene Ontology“…Here we survey bacterial secretion systems known to modulate interactions with host organisms and describe Gene Ontology terms useful for describing the components and functions of these systems, and for capturing the similarities among the diverse systems.…”
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765“…BACKGROUND: Various measures of semantic similarity of terms in bio-ontologies such as the Gene Ontology (GO) have been used to compare gene products. …”
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766por Feltrin, Erika, Campanaro, Stefano, Diehl, Alexander D, Ehler, Elisabeth, Faulkner, Georgine, Fordham, Jennifer, Gardin, Chiara, Harris, Midori, Hill, David, Knoell, Ralph, Laveder, Paolo, Mittempergher, Lorenza, Nori, Alessandra, Reggiani, Carlo, Sorrentino, Vincenzo, Volpe, Pompeo, Zara, Ivano, Valle, Giorgio, Deegan née Clark, Jennifer“…In a collaboration between the Gene Ontology (GO) Consortium and the muscle biology community, we have made large-scale additions to the GO biological process and cellular component ontologies. …”
Publicado 2009
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767por Alexopoulou, Dimitra, Andreopoulos, Bill, Dietze, Heiko, Doms, Andreas, Gandon, Fabien, Hakenberg, Jörg, Khelif, Khaled, Schroeder, Michael, Wächter, Thomas“…BACKGROUND: Ontology term labels can be ambiguous and have multiple senses. …”
Publicado 2009
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768por Hoehndorf, Robert, Bacher, Joshua, Backhaus, Michael, Gregorio, Sergio E, Loebe, Frank, Prüfer, Kay, Uciteli, Alexandr, Visagie, Johann, Herre, Heinrich, Kelso, Janet“…MOTIVATION: Ontology development and the annotation of biological data using ontologies are time-consuming exercises that currently require input from expert curators. …”
Publicado 2009
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769por Schober, Daniel, Smith, Barry, Lewis, Suzanna E, Kusnierczyk, Waclaw, Lomax, Jane, Mungall, Chris, Taylor, Chris F, Rocca-Serra, Philippe, Sansone, Susanna-Assunta“…Integration of these ontologies, while requiring considerable effort, is extremely desirable. …”
Publicado 2009
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770por Li, Chuan-Yun, Liu, Qing-Rong, Zhang, Ping-Wu, Li, Xiao-Mo, Wei, Liping, Uhl, George R.“…We now report compilation of 496 human CAM genes in six gene families based on manual curation of protein domain structures, Gene Ontology annotations, and 1487 NCBI Entrez annotations. …”
Publicado 2009
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771por Noy, Natalya F., Shah, Nigam H., Whetzel, Patricia L., Dai, Benjamin, Dorf, Michael, Griffith, Nicholas, Jonquet, Clement, Rubin, Daniel L., Storey, Margaret-Anne, Chute, Christopher G., Musen, Mark A.“…BioPortal (http://bioportal.bioontology.org) is an open repository of biomedical ontologies that provides access via Web services and Web browsers to ontologies developed in OWL, RDF, OBO format and Protégé frames. …”
Publicado 2009
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772“…Motivation: There is a growing interest in improving the cluster analysis of expression data by incorporating into it prior knowledge, such as the Gene Ontology (GO) annotations of genes, in order to improve the biological relevance of the clusters that are subjected to subsequent scrutiny. …”
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773“…Typical examples of such lists are the differentially expressed genes from transcriptional analysis which need to be linked to functional information represented in the Gene Ontology (GO). Despite the importance of this procedure, there is a little work on consistent evaluation of various GO analysis methods. …”
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774por Binns, David, Dimmer, Emily, Huntley, Rachael, Barrell, Daniel, O'Donovan, Claire, Apweiler, Rolf“…Summary: QuickGO is a web-based tool that allows easy browsing of the Gene Ontology (GO) and all associated electronic and manual GO annotations provided by the GO Consortium annotation groups QuickGO has been a popular GO browser for many years, but after a recent redevelopment it is now able to offer a greater range of facilities including bulk downloads of GO annotation data which can be extensively filtered by a range of different parameters and GO slim set generation. …”
Publicado 2009
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775“…RESULTS: In order to facilitate the location of the correct term in the correct controlled vocabulary or ontology, the Ontology Lookup Service was created. …”
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776“…In this paper, we explicate that realism, naturalism, reductionism, and essentialism are core ontological assumptions of the medical model of psychiatry. …”
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778por Antezana, Erick, Venkatesan, Aravind, Mungall, Chris, Mironov, Vladimir, Kuiper, Martin“…The resulting ONTO-ToolKit supports the analysis and handling of OBO-formatted ontologies via the Galaxy interface, and we demonstrated its functionality in different use cases that illustrate the flexibility to obtain sets of ontology terms that match specific search criteria. …”
Publicado 2010
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779por Green, Jason M., Harnsomburana, Jaturon, Schaeffer, Mary L., Lawrence, Carolyn J., Shyu, Chi-Ren“…Furthermore, though much time and effort have been afforded to the development of plant-related ontologies, the knowledge embedded in these ontologies remains largely unused in available plant search mechanisms. …”
Publicado 2011
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780“…BACKGROUND: The Gene Ontology project supports categorization of gene products according to their location of action, the molecular functions that they carry out, and the processes that they are involved in. …”
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