Mostrando 961 - 980 Resultados de 23,929 Para Buscar '"Ontology"', tiempo de consulta: 0.22s Limitar resultados
  1. 961
    “…BACKGROUND: Recent increases in the volume and diversity of life science data and information and an increasing emphasis on data sharing and interoperability have resulted in the creation of a large number of biological ontologies, including the Cell Ontology (CL), designed to provide a standardized representation of cell types for data annotation. …”
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  2. 962
    “…To describe phenotypes using ontologies, we used an Entity-Quality (EQ) methodology, wherein the affected entity (E) and how it is affected (Q) are recorded using terms from a variety of ontologies. …”
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  3. 963
  4. 964
    “…A total of 4,617 phenotypic characters (10,512 states) for 3,449 taxa, primarily species, were curated into EQ formalism (for a total of 12,861 EQ statements) using anatomical and taxonomic terms from teleost-specific ontologies (Teleost Anatomy Ontology and Teleost Taxonomy Ontology) in combination with terms from a quality ontology (Phenotype and Trait Ontology). …”
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  5. 965
    “…The study of gene set function most commonly makes use of controlled vocabulary in the form of ontology annotations. For a given gene set, the statistical significance of observing these annotations or ‘enrichment’ may be tested using a number of methods. …”
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  6. 966
    “…Motivation: The anatomy of model species is described in ontologies, which are used to standardize the annotations of experimental data, such as gene expression patterns. …”
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  7. 967
    “…Results: Here, we introduce MedSim, a novel approach for ranking candidate genes for a particular disease based on functional comparisons involving the Gene Ontology. MedSim uses functional annotations of known disease genes for assessing the similarity of diseases as well as the disease relevance of candidate genes. …”
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  8. 968
    “…The connectivity between molecular states across thousands of heterogeneous datasets from microarrays and other genomic platforms is determined through a combination of rank-based enrichment statistics, meta-analyses, and biomedical ontologies. We address data quality concerns through dataset replication and meta-analysis and ensure that the majority of the findings are derived using multiple lines of evidence. …”
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  9. 969
  10. 970
    “…The new methodology is general purpose and has been used to produce domain-based phenotypic ontologies in addition to GO.…”
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  11. 971
    “…In addition to gene expression values, the proposed method uses Gene Ontology which is a reliable source of information on genes. …”
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  12. 972
    “…This approach is applied to data in Cell System Ontology which is a comprehensive ontology that represents complex biological pathways with dynamics and visualization. …”
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  13. 973
  14. 974
    “…RESULTS: In this work we show that using PPAN data combined with other approximations, such as functional module detection, orthology exploitation methods and Gene Ontology (GO)-based information measures helps to predict protein function in Mycoplasma genitalium. …”
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  15. 975
    “…Structured information provided by manual annotation of proteins with Gene Ontology concepts represents a high-quality reliable data source for the research community. …”
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  16. 976
    “…One critical aspect in the application of cheminformatics in these fields is the accurate exchange of data, which is increasingly accomplished through the use of ontologies. Ontologies are formal representations of objects and their properties using a logic-based ontology language. …”
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  17. 977
    “…In this study, we conducted a population genetic study using the HapMap genotype data to identify certain special Gene Ontology (GO) categories associated with high/low genetic difference among 11 Hapmap populations. …”
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  18. 978
    “…In addition, we provide a software application to convert annotated GENIA abstracts into OWL ontologies by combining both the ontology of relations and the design patterns. …”
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  19. 979
    por Prodanov, Dimiter
    Publicado 2011
    “…Instrumental for the latter feat was the construction of a data ontology representing the common measurement data model. …”
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  20. 980
    “…We then briefly describe SKELETOME, a community-driven knowledge curation platform that is underpinned by the Bone Dysplasia Ontology. SKELETOME enables domain experts to use, refine and extend and apply the ontology without any prior ontology engineering experience--to advance the body of knowledge in the skeletal dysplasia field. …”
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