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18921“…Further evaluation was performed on the basis of the following analyses: clinicopathology and survival analysis, gene ontology (GO) terms, and Kyoto Encyclopedia of Genes and Genomes (KEGG) pathway analysis, as well as multi-omics immunotherapy-related analysis and co-expression analysis. …”
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18922“…A functional enrichment analysis of genes potentially targeted by downregulation of certain miRNAs at the initiation of symbiosis revealed two major gene ontology (GO) term categories, neurodevelopment and tissue remodeling. …”
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18923“…Finally, we conducted gene ontology (GO) enrichment analysis and gene set enrichment analysis (GSEA) to explore possible mechanisms and gene co-expression analysis was also be performed. …”
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18924por Sun, Jin-Yu, Hua, Yang, Shen, Hui, Qu, Qiang, Kan, Jun-Yan, Kong, Xiang-Qing, Sun, Wei, Shen, Yue-Yun“…Then, enrichment analysis was performed based on Gene ontology (GO) and Kyoto Encyclopedia of Genes and Genomes (KEGG) pathway, DisGeNET, and TRRUST database. …”
Publicado 2021
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18925“…Through differential gene expression analysis, gene ontology analysis, Kyoto Encyclopedia of Genes and Genomes analysis, gene set enrichment analysis, and correlation analysis, we further explored the relationship between glycolytic activity and immune function. …”
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18926“…Pearson correlation analysis was performed to measure the correlation between the expression of splicing factors (SFs) and the percent spliced in (PSI) values of AS events. Gene ontology (GO) and Kyoto Encyclopedia of Genes and Genomes (KEGG) were conducted to demonstrate pathways in which survival-associated AS event is enriched. …”
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18927por Yuan, Xin, Hu, Shenqiang, Li, Liang, Han, Chunchun, Liu, Hehe, He, Hua, Xia, Lu, Hu, Jiwei, Hu, Bo, Ran, Mingxia, Liu, Yali, Wang, Jiwen“…Furthermore, transcriptomics identified differentially expressed genes (DEGs), some of which were assigned to lipid-related Gene Ontology slim terms. More DEGs were assigned in the SCD-knockdown group than in the SCD-overexpression group. …”
Publicado 2021
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18928“…Differentially expressed genes (DEGs) were significantly enriched in various Gene Ontology (GO) terms, including cellular process, binding, and cell part. …”
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18929por Romera-Giner, Sergio, Andreu Martínez, Zoraida, García-García, Francisco, Hidalgo, Marta R.“…RESULTS: After a tumor versus normal tissue comparison of the signaling pathways and cell functions, we found 828 subpathways, 912 Gene Ontology terms and 91 Uniprot keywords commonly significant to the three studied tumors. …”
Publicado 2021
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18930por Zhang, Juanli, Zhao, Jiaxin, Ma, Yang, Wang, Wenjun, Huang, Shaojie, Guo, Chao, Wang, Kai, Zhang, Xiaomei, Zhang, Wei, Wen, Aidong, Shi, Ming, Ding, Yi“…Seven core components in GXSTC and 12 core genes of GXSTC on CBVDs were further determined using the protein-protein interaction (PPI) and component-target-pathway (C-T-P) network analysis. Gene Ontology (GO) and Kyoto Encyclopedia of Genes and Genomes (KEGG) pathway enrichment analysis results predicted that the molecular mechanisms of GXSTC on CBVDs were mainly associated with the regulation of the vascular endothelial function, inflammatory response, and neuronal apoptosis. …”
Publicado 2021
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18931“…In addition, many DEGs related to cell death, lipid metabolism, major sperm proteins, proteinases/peptidases, phosphatases, kinases, virulence factors, and transthyretin-like proteins were downregulated. Gene Ontology enrichment analysis showed that the CytCo treatment substantially affected DEGs involved in muscle contraction, lipid localization, and the mitogen-activated protein kinase cascade. …”
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18932por Nisar, Muhammad Azhar, Zheng, Qin, Saleem, Muhammad Zubair, Ahmmed, Bulbul, Ramzan, Muhammad Noman, Ud Din, Syed Riaz, Tahir, Naeem, Liu, Shuai, Yan, Qiu“…Furthermore, the STRING and Gene Ontology database was also used to analyze the VM-associated interacting molecules stimulated by IL-β. …”
Publicado 2021
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18933por Aihaiti, Yirixiati, Song Cai, Yong, Tuerhong, Xiadiye, Ni Yang, Yan, Ma, Yao, Shi Zheng, Hai, Xu, Ke, Xu, Peng“…The protein–protein interaction (PPI) networks of intersected targets were constructed using the STRING database and visualized using Cytoscape. Gene Ontology (GO) and Kyoto Encyclopedia of Genes and Genomes (KEGG) pathway enrichment analyses were performed, and the pathways directly related to pathogenesis of RA were integrated manually. …”
Publicado 2021
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18934por Yoshikawa, Akane, Kushima, Itaru, Miyashita, Mitsuhiro, Toriumi, Kazuya, Suzuki, Kazuhiro, Horiuchi, Yasue, Kawaji, Hideya, Takizawa, Shunya, Ozaki, Norio, Itokawa, Masanari, Arai, Makoto“…The number of CNV-miRNAs and the gene ontology (GO) in the context of miRNAs within CNVs were compared between PEN-SCZ and non-PEN-SCZ groups. …”
Publicado 2021
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18935por Zhang, Yang“…The target genes of DEMs were predicted via TargetScanHuman7.2 and miRDB, and then intersected with DEGs. Gene Ontology and Kyoto Encyclopedia of Genes and Genomes analyses of overlapping genes were conducted, followed by construction of protein-protein interaction network. …”
Publicado 2021
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18936por He, Yayi, Chen, Linsong, Zhao, Lishu, Dang, Shiying, Liu, Guifeng, Sasada, Shinji, Ma, Patrick C., van Zandwijk, Nico, Rosell, Rafael, Popper, Helmut H., Wang, Hao, Jiang, Minlin, Guo, Haoyue, Liu, Xinyi, Chen, Shifu, Zhang, Xiaoni, Xu, Mingyan, Zhu, Bo, Liu, Ming, Zhou, Caicun“…Characteristic mutational alterations in 1574 genes were investigated based on mutational status, clinicopathological factors, and chemotherapy responses. Gene Ontology (GO) and Kyoto Encyclopedia of Genes and Genomes (KEGG) pathway enrichment analysis, neoantigen prediction and intratumoral heterogeneity evaluation were also performed. …”
Publicado 2021
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18937“…Through correlation analysis, we identified 11 dysregulated circRNAs, 7 dysregulated miRNAs and 8 dysregulated mRNAs forming 16 relationships in the circRNA-miRNA-mRNA regulatory network. Gene ontology (GO) analysis indicated that the dysregulated circRNAs were most enriched in biological metabolic processes. …”
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18938por Zhang, Guang-Zhi, Wu, Zuo-Long, Li, Chun-Ying, Ren, En-Hui, Yuan, Wen-Hua, Deng, Ya-Jun, Xie, Qi-Qi“…We acquired an autophagy gene list from the Human Autophagy Database (HADb) and identified autophagy-related lncRNAs by co-expression analyses. Gene Ontology (GO) and Kyoto Encyclopedia of Genes and Genomes (KEGG) pathway enrichment analyses of the autophagy-related lncRNAs were conducted. …”
Publicado 2021
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18939por Al Madhoun, Ashraf, Haddad, Dania, Al Tarrah, Mustafa, Jacob, Sindhu, Al-Ali, Waleed, Nizam, Rasheeba, Miranda, Lavina, Al-Rashed, Fatema, Sindhu, Sardar, Ahmad, Rasheed, Bitar, Milad S., Al-Mulla, Fahd“…Unlike LS-174T cells, SW480 cells were resistant to ONC201 treatment; Gene Ontology analysis of differentially expressed genes showed that cellular responsiveness to ONC201 treatment also differed substantially. …”
Publicado 2021
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18940“…RESULT: In this study, based on nanoscale liquid chromatography mass spectrometry analysis (LC-MS/MS), the tandem mass tag (TMT) labeling analysis was used to investigate the differentially abundant proteins (DAPs) related with the differentiation process of goat intramuscular adipocytes. Gene Ontology, Kyoto Encyclopedia of Genes and Genomes enrichment and protein-protein interaction network analyses were performed for the characterization of the identified DAPs. …”
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