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19101“…Common differentially expressed genes (DEGs) were identified through differential expression analysis. Gene Ontology (GO) and Kyoto Encyclopedia of Genes and Genomes (KEGG) enrichment analyses were performed. …”
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19102por Chen, Jia, Chen, Yuhan, Du, Xue, Liu, Guojun, Fei, Xiaowei, Peng, Jian Ru, Zhang, Xing, Xiao, Fengjun, Wang, Xue, Yang, Xiao, Feng, Zhichun“…Importantly, pathway analysis integrating Gene Ontology (GO)/Kyoto Encyclopedia of Genes and Genomes (KEGG)/gene set enrichment analysis (GSEA) method indicates that the competing endogenous RNA (ceRNA) network is mainly related to the regulation of GTPase activity (GO: 0043087), extracellular signal-regulated kinase 1 (ERK1) and ERK2 signal cascade (GO: 0070371), chromosome regulation (GO: 0007059), and cell cycle control (GO: 0044770). …”
Publicado 2021
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19103por Yang, Shuheng, Zheng, Wei, Yang, Chen, Zu, Ruowen, Ran, Shiyu, Wu, Huan, Mu, Mingkun, Sun, Simin, Zhang, Nana, Thorne, Rick F., Guan, Yichun“…METHODS: Full-term human placental tissues were subjected to next-generation sequencing to determine differentially expressed miRNAs (DEmiRs) and genes (DEGs) between uncomplicated IVF-ET assisted and naturally conceived pregnancies. Gene ontology (GO) enrichment analysis and transcription factor enrichment analysis were used for DEmiRs. …”
Publicado 2021
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19104“…Nine candidate genes (ACACA, SCAF4, SLC2A5, TNMD, PCDH1, FOXO, AGO1, FFAR3, and ARID1A) underlying the feed efficiency trait were also identified, the biological functions of which may be involved in lipid metabolism, carbohydrate metabolism, energy deposition, fat accumulation, digestion, growth regulation, and cell proliferation and differentiation according to GO (Gene Ontology). As an important tool, high-density and high-resolution genetic linkage maps play a crucial role in the QTL fine mapping of economically important traits. …”
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19105por Wen, Yunfei, Raza, Ali, Chu, Wen, Zou, Xiling, Cheng, Hongtao, Hu, Qiong, Liu, Jia, Wei, Wenliang“…Moreover, 32 bna-miRNAs from 14 families were found to be targeting 21 BnTCPs genes. Gene ontology enrichment analysis presented that the BnTCP genes were primarily related to RNA/DNA binding, metabolic processes, transcriptional regulatory activities, etc. …”
Publicado 2021
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19106“…Differences in immune functions and expression of immune checkpoint inhibitors and m6A regulators between high-risk and low-risk groups were further explored. Finally, Gene Ontology (GO) and Kyoto Encyclopedia of Genes and Genomes (KEGG) analyses were utilized to explore the biological functions of AL122125.1. …”
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19107“…We also investigated the potential molecular mechanisms of IRGs through a bioinformatics approach using Protein-Protein Interaction (PPI) network, Kyoto Encyclopedia of Genes and Genomes (KEGG) database analysis and Gene Ontology (GO) database analysis. Differentially expressed IRGs associated with significant clinical outcomes (SIRGs) were identified by univariate Cox regression analysis. …”
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19108“…Furthermore, LinkedOmics was used to identify the genes coexpressed with SMOC1 and to perform Kyoto Encyclopedia of Genes and Genomes pathways and Gene Ontology analysis in low-grade glioma (LGG). Also, the Cancer Single-Cell State Atlas database was used to evaluate the correlation between SMOC1 expression and functional state activities in glioma cells. …”
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19109por Fan, Guoju, Jin, Zhihai, Wang, Kaiqiang, Yang, Huitang, Wang, Jun, Li, Yankui, Chen, Bo, Zhang, Hongwei“…METHODS: Two human datasets (GSE19151 and GSE48000) were analyzed by the robust rank aggregation method. Gene ontology and Kyoto encyclopedia of genes and genomes pathway enrichment analyses were conducted for the DEGs. …”
Publicado 2021
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19110por Khan, Ibrar Muhammad, Liu, Hongyu, Zhuang, Jingyi, Khan, Nazir Muhammad, Zhang, Dandan, Chen, Jingmeng, Xu, Tengteng, Avalos, Lourdes Felicidad Córdova, Zhou, Xinqi, Zhang, Yunhai“…Among these DE circRNAs, 579 were upregulated and 103 were downregulated in calf and bull testes. The Gene Ontology (GO) and Kyoto Encyclopedia of Genes and Genomes (KEGG) pathway enrichment analyses revealed that the identified target genes were classified into three broad functional categories, including biological process, cellular component, and molecular function, and were enriched in the lysine degradation, cell cycle, and cell adhesion molecule pathways. …”
Publicado 2021
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19111por Zhang, Huihao, Yao, Sai, Zhang, Zhiguo, Zhou, Chengcong, Fu, Fangda, Bian, Yishan, Luo, Huan, Li, Yan, Yan, Shuxin, Ge, Yuying, Chen, Yuying, Zhan, Kunyu, Ge, Yanzhi, Chen, Zuxiang, Yue, Ming, Li, Xiaofeng, Du, Weibin, Jin, Hongting, Tong, Peijian, Ruan, Hongfeng, Wu, Chengliang“…The protein–protein interaction (PPI) network, Gene Ontology (GO) and Kyoto Encyclopedia of Genes and Genomes (KEGG) functional enrichment analyses were performed to predict the core targets and pathways of LWDHD against IVDD. …”
Publicado 2021
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19112por Gong, Ke, Zhou, Huiling, Liu, Haidan, Xie, Ting, Luo, Yong, Guo, Hui, Chen, Jinlan, Tan, Zhiping, Yang, Yifeng, Xie, Li“…Venn diagram software was applied to screen differentially expressed genes, and gene ontology functional analysis and Kyoto Encyclopedia of Genes and Genomes (KEGG) pathway analysis were performed. …”
Publicado 2021
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19113“…DEGs were analyzed by Gene Ontology function and Kyoto Encyclopedia of Genes and Genomes pathway enrichment analysis. …”
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19114“…RESULTS: First, we used univariate analysis to identify 35 prognostic genes, which were further demonstrated to be associated with starvation metabolism through Kyoto Encyclopedia of Genes and Genomes (KEGG) and Gene Ontology (GO). We then used multivariate analysis to build a model with nine genes. …”
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19115“…Molecular biological processes and signaling pathways were determined via bioinformatic analysis, containing protein-protein interaction (PPI), Gene Ontology (GO), and Kyoto Encyclopedia of Genes and Genomes (KEGG). …”
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19116“…The results of Gene Ontology (GO) and Kyoto Encyclopedia of Genes and Genomes (KEGG) pathway analysis indicated that these target genes of DEmiRNAs were associated with various biological processes (BPs). …”
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19117por Wang, Dan, Liu, Yicheng, Tang, Dandan, Wei, Shujun, Sun, Jiayi, Ruan, Lvqiang, He, Lin, Li, Ruolan, Ren, Qiang, Tian, Xiaoping, Chen, Yunhui“…By bioinformatics annotation on these key genes, a total of 354 gene ontology (GO) functional annotation analyses and 42 Kyoto Encyclopedia of Genes and Genomes (KEGG) pathways were obtained. …”
Publicado 2021
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19118por Zhuang, Jujuan, Ren, Changjing, Ren, Dan, Li, Yu’ang, Liu, Danyang, Cui, Lingyu, Tian, Geng, Yang, Jiasheng, Liu, Jingbo“…Specifically, we first derive the functional gene sets based on Gene Ontology (GO) terms and reduce their redundancy by semantic similarity analysis and gene repetitive rate reduction. …”
Publicado 2021
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19119por Han, Yunhe, Zou, Cunyi, Zhu, Chen, Liu, Tianqi, Shen, Shuai, Cheng, Peng, Cheng, Wen, Wu, Anhua“…Kaplan-Meier curves and time-dependent receiver operating characteristic (ROC) curves and multivariate Cox regression analysis, were utilized to evaluate the prognostic capacity of the four-gene signature. Gene ontology (GO)enrichment analysis and Gene Set Enrichment Analyses (GSEA) were performed to further understand the underlying molecular mechanisms. …”
Publicado 2021
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19120por Ma, Pengtao, Wu, Liru, Xu, Yufei, Xu, Hongxing, Zhang, Xu, Wang, Wenrui, Liu, Cheng, Wang, Bo“…To explore the potential regulatory genes of the R gene, 2,973 differentially expressed genes (DEGs) between the parents and bulks were analyzed using gene ontology (GO), clusters of orthologous group (COG), and Kyoto Encyclopedia of Genes and Genomes (KEGG) pathway enrichment analysis. …”
Publicado 2021
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