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19441por Zhang, Xiyan, Zhang, Xude, Feng, Shaojie, Wang, Xijuan, Guo, Beibei, Liu, Jingjing, Xu, Donghua, Liu, Fengxia“…Bioinformatics approaches, including miRanda, Gene Ontology (GO) and the Kyoto Encyclopedia of Genes and Genomes (KEGG) databases, were employed to predict novel therapeutic and diagnostic targets for allergic asthma. …”
Publicado 2022
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19442por Alhajhoj, Mohammed Refdan, Munir, Muhammad, Sudhakar, Balakrishnan, Ali-Dinar, Hassan Muzzamil, Iqbal, Zafar“…A total of 1118 drought-responsive expressed sequence tags (ESTs) were sequenced, 345 from Khalas, 391 from Reziz, and 382 from Sheshi and subjected to functional characterization, gene ontology classification, KEGG pathways elucidation, and enzyme codes dissemination. …”
Publicado 2022
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19443por Zhang, Fengjun, Xia, Mingyue, Jiang, Jiarong, Wang, Shuai, Zhao, Qiong, Yu, Cheng, Yu, Jinzhen, Xian, Dexian, Li, Xiao, Zhang, Lin, Liu, Yuan, Peng, Min“…The correlation analysis of AR-DEGs and their visualization were performed using R language. Gene Ontology (GO) enrichment analysis and combined multi-database pathway analysis were served by the Enrichr online enrichment analysis platform. …”
Publicado 2022
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19444“…A protein–protein interaction network was constructed when the genes in the modules were enriched and examined by Gene Ontology (GO)/Kyoto Encyclopedia of Genes and Genomes (KEGG) analysis. …”
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19445“…Key targets and enrichment pathways were identified using Gene Ontology (GO) term enrichment and Kyoto Encyclopedia of Genes and Genomes (KEGG) pathway analysis. …”
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19446por Zhang, Weiguang, Zhang, Peipei, Jiang, Junfei, Peng, Kaiming, Shen, Zhimin, Kang, Mingqiang“…METHODS: RNA-seq data of ESCC were download from the NCBI Gene Expression Omnibus (GEO) database. Gene Ontology (GO) analysis and Kyoto Encyclopedia of Genes and Genomes (KEGG) analysis were used to explore the potential biological functions or pathways. …”
Publicado 2022
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19447por Liao, Mingjuan, Zhang, Rong, Wang, Yongling, Mao, Ziming, Wu, Jing, Guo, Huaqi, Zhang, Kaiwen, Jing, Yu, Zhang, Caoxu, Song, Huaidong, Chen, Xia, Wei, Gang“…With these DEGs, we observed a marked enrichment of Gene Ontology (GO) terms and Kyoto Encyclopedia of Genes and Genomes (KEGG) pathways, which were closely associated with the metabolic balance in liver. …”
Publicado 2022
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19448por Li, Tian-Hao, Wang, Yuan-Yang, Zhao, Bang-Bo, Qin, Cheng, Li, Ze-Ru, Wang, Wei-Bin“…Further, we conducted Gene ontology (GO) analysis, Gene set enrichment analysis (GSEA), single sample gene set enrichment analysis (ssGSEA) and estimate analysis to explore the association between PLAAT4 and biological function and immune infiltration. …”
Publicado 2022
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19449“…The network of target protein-protein interactions (PPI) was constructed using the STRING database, while gene ontology (GO) functional terms and the Kyoto Encyclopaedia of Genes and Genomes (KEGG) pathways associated with potential targets were analyzed using a program in R language (version 4.2.0). …”
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19450por Huang, Xing, Feng, Yipeng, Ma, Dawei, Ding, Hanlin, Dong, Gaochao, Chen, Yan, Huang, Xiaochen, Zhang, Jingyuan, Xu, Xinyu, Chen, Chen“…The results indicated that gene expression changed dramatically, specifically at the intraductal papillary-mucinous adenoma (IPMA) stage. Gene ontology (GO), Kyoto Encyclopedia of Genes and Genomes (KEGG), and Kyoto Encyclopedia of Genes and Genomes (GSEA) pathway analyses showed that glycoprotein-related, cell cycle, and P53 pathways displayed the most significant changes during progression. …”
Publicado 2022
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19451por Qin, Si, Zhang, Lan-Yue, Zhang, Hao-Bin, Shi, Si-Man, Zhou, Xin, Lu, Zhen-Yu, Duan, Yi-Xue, Huang, Wen-Bin, Wen, Ju“…In addition, as bioinformatics analysis methods, Gene Ontology (GO) analysis and Kyoto Encyclopedia of Genes and Genomes (KEGG) pathway analysis were used in our research as supplementary means to network pharmacology. …”
Publicado 2022
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19452por Li, Yufeng, Tang, Haizhou, Huang, Zhenwen, Qin, Huaxing, Cen, Qin, Meng, Fei, Huang, Liang, Lin, Lifang, Pu, Jian, Yang, Di“…For the common DEGs, the top 30 significant results of Gene Ontology (GO) and Kyoto Encyclopedia of Genes and Genomes (KEGG) pathways enrichment analyses were presented. …”
Publicado 2022
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19453por Xiong, Yongqin, Lin, Jiaji, Bian, Xiangbing, Lu, Haoxuan, Zhou, Jiayou, Zhang, Dekang, Pan, Longsheng, Lou, Xin“…It was correlated with an expression map of a weighted combination genes enriched for mitochondria relevant ontology terms. This study demonstrates that the therapeutic effects of MRgFUS thalamotomy on ET are associated with modulating a distinct ET-related network which may be driven by mitochondria relevant neurobiological mechanism. …”
Publicado 2022
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19454por Saffery, Nik Syazana Izyan, Genasan, Krishnamurithy, Chan, Chee Ken, Ayob, Khairul Anwar, Teo, Seow Hui, Al-Fayyadh, Mohamed Zubair Mohamed, Othman, Iekhsan, Abidin, Syafiq Asnawi Zainal, Raman, Murali Malliga, Raghavendran, Hanumantha Rao Balaji, Kamarul, Tunku“…The STRING protein network analysis indicated distinctive links between proteins and gene ontology (GO) and revealed proteins associated with leukocyte-mediated immunity in OAS as compared to TBC. …”
Publicado 2022
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19455por Cao, Jun-Feng, Xingyu Yang, Li Xiong, Wu, Mei, Chen, Shengyan, Xu, Hengxiang, Gong, Yunli, Zhang, Lixin, Zhang, Qilan, Zhang, Xiao“…Results: The protein interaction network screened out the core protein targets (such as: NLRP3, TNF, IL1B) of gouty arthritis. Gene ontology (GO) and Kyoto Encyclopedia of Genes and Genomes (KEGG) analysis revealed that gouty arthritis mainly played a vital role by the signaling pathways of inflammation and immune response. …”
Publicado 2022
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19456por Du, YiKuan, He, LuLu, Ye, XinNi, Chen, ShuZhen, Li, GuanHao, Yu, YuanWei, Ye, ErBai, Huang, YiXing, Zhou, YuQi, Zhang, WeiChui, Yang, Chun“…Eight hub genes including interleukin-6 (IL-6), interleukin-10 (IL-10), Toll-like receptor 4 (TLR4), signal transduction and transcriptional activation factor 3 (STAT3), C-X-C motif chemokine 10 (CXCL10), interleukin-17A (IL-17A), prostaglandin peroxide synthesis-2 (PTGS2), signal transistors, and transcriptional activation factor 6 (STAT6) were identified by gene ontology (GO), Kyoto Encyclopedia of Genes (KEGG), and PPI network analysis. …”
Publicado 2022
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19457por Dai, Yu-yang, Gao, Yi-ping, Chen, Lin-xin, Liu, Jin-song, Zeng, Cheng, Zhou, Jian-dong, Wu, Hong-lin“…In addition, the potential functions of lncRNAs in the novel signature were explored through Gene Ontology (GO) and Kyoto Encyclopedia of Genes and Genomes (KEGG) analyses and gene set enrichment analysis (GSEA). …”
Publicado 2022
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19458por Peng, YunZhen, Wu, GuoJing, Qiu, Xin, Luo, Yue, Zou, YiShu, Wei, XueYan, Li, Aimin“…The Wilcoxon method was used to detect differentially expressed genes, and prognostic relevant lncRNAs were obtained by univariate Cox regression analysis. Gene Ontology and Kyoto Encyclopedia of Genes and Genomes analysis were utilized to perform functional enrichment analysis. …”
Publicado 2022
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19459por Zhu, Yue-Qian, Zhou, Nai-Hui, Xu, Ya-Wen, Liu, Ke, Li, Wei, Shi, Li-Yan, Hu, Yin-Xi, Xie, Yu-Feng, Lan, Jing, Yu, Zheng-Yuan“…The Kyoto Encyclopedia of Genes and Genomes (KEGG) pathway analysis revealed that the mutated genes were mainly concentrated in micro ribonucleic acids in cancer and the calcium signaling pathway. The Gene Ontology (GO) analysis showed that mutant genes were mainly concentrated in binding cells, cell parts, and cellular processes. …”
Publicado 2022
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19460por Song, Xiangjun, Chen, Zhe, Li, Ziqi, Wang, Xiaoru, Hou, Manman, Shao, Ying, Tu, Jian, Qi, Kezong“…A total of 195 differentially expressed proteins (DEPs) were detected in the overexpression group (upregulated, n = 144, downregulated, n = 51). Gene Ontology (GO) and Kyoto Encyclopedia of Genes and Genomes (KEGG) analyses were performed to predict the biological functions and pathways of differentially expressed proteins. …”
Publicado 2022
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