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1001por Schwall, Christian P, Loman, Torkel E, Martins, Bruno M C, Cortijo, Sandra, Villava, Casandra, Kusmartsev, Vassili, Livesey, Toby, Saez, Teresa, Locke, James C W“…Iteration between model and experiment reveals that this tunability can be explained by the autoregulatory feedback structure of the sigV operon. As predicted by the model, genetic perturbations to the operon also modulate the response variability. …”
Publicado 2021
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1002por Damle, Madhura S., Singh, Aarshi N., Peters, Stephen C., Szalai, Veronika A., Fisher, Oriana S.“…The Gram-positive bacterium Bacillus subtilis maintains appropriate copper homeostasis in part through the ycn operon. The ycn operon comprises genes encoding three proteins: the putative copper importer YcnJ, the copper-dependent transcriptional repressor YcnK, and the uncharacterized Domain of Unknown Function 1775 (DUF1775) containing YcnI. …”
Publicado 2021
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1003por Nakamya, Mary F., Ayoola, Moses B., Shack, Leslie A., Swiatlo, Edwin, Nanduri, Bindu“…Our results also show that the potABCD operon protects pneumococci against hydrogen peroxide and nitrosative stress. …”
Publicado 2021
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1004por Burgess, Sara A., Palevich, Faith P., Gardner, Amanda, Mills, John, Brightwell, Gale, Palevich, Nikola“…All the genomes analysed contained at least one gerX operon. Seven different gerX operon configuration types were identified across genomes from C. estertheticum , C. tagluense and C. gasigenes . …”
Publicado 2022
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1005por Morales-Laverde, Liliana, Echeverz, Maite, Trobos, Margarita, Solano, Cristina, Lasa, Iñigo“…Moreover, polymorphisms in these IGRs did not significantly affect transcription of the icaADBC operon under in vitro laboratory conditions. In contrast, an SNP within the icaR coding region, resulting in a V176E change in the transcriptional repressor IcaR, led to a significant increase in icaADBC operon transcription and PIA/PNAG production and a reduction in S. aureus virulence in a Galleria mellonella infection model. …”
Publicado 2022
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1006por Rozner, Marlena, Nukarinen, Ella, Wolfinger, Michael T., Amman, Fabian, Weckwerth, Wolfram, Bläsi, Udo, Sonnleitner, Elisabeth“…A model for indirect regulation of the mexGHI-opmD operon by Hfq is presented.…”
Publicado 2022
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1007por Frantsuzova, Ekaterina, Delegan, Yanina, Bogun, Alexander, Sokolova, Diyana, Nazina, Tamara“…This paper presents a comparative bioinformatic analysis of complete genomes of strain 6-1 and dibenzothiophene-degrading Gordonia strains 1D and 135 that do not have the dsz operon. The assumption is made about the participation in this process of the region containing the sfnB gene. …”
Publicado 2022
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1008por Larson, James, Tokmina-Lukaszewska, Monika, Fausset, Hunter, Spurzem, Scott, Cox, Savannah, Cooper, Gwendolyn, Copié, Valérie, Bothner, Brian“…In E. coli, the proteins encoded by the arsRBC operon are the major arsenic detoxification mechanism. …”
Publicado 2023
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1009por Elankumuran, Paarthiphan, Browning, Glenn F., Marenda, Marc S., Kidsley, Amanda, Osman, Marwan, Haenni, Marisa, Johnson, James R., Trott, Darren J., Reid, Cameron J., Djordjevic, Steven P.“…We show that multiple acquisitions of the pdu propanediol utilization operon have occurred in clusters dominated by isolates of canine source, possibly linked to diet, whereas loss of the pdu operon and acquisition of K antigen virulence genes characterize human-restricted lineages.…”
Publicado 2023
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1010por Siddaramappa, Shivakumara, Challacombe, Jean F, Petersen, Jeannine M, Pillai, Segaran, Kuske, Cheryl R“…Strain ATCC 25017 contained an operon putatively involved in lactose metabolism that was absent in strain TX07-7308, F. novicida strain U112, and F. tularensis strain Schu S4. …”
Publicado 2012
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1011por Bruckbauer, Steven T, Kvitko, Brian H, Karkhoff-Schweizer, RoxAnn R, Schweizer, Herbert P“…Sequencing of the lux-chromosomal DNA junctions on the plasmid reveals transposon insertion sites within genes or operons. The plasmid is also a mini-Tn7-lux delivery vector that can be used to introduce the promoter-lux operon fusion into other derivatives of the bacterium of interest in an isogenic fashion. …”
Publicado 2015
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1012por Irla, Marta, Neshat, Armin, Brautaset, Trygve, Rückert, Christian, Kalinowski, Jörn, Wendisch, Volker F“…The analysis of the operon structures revealed that almost half of the genes are transcribed monocistronically (940), whereas 1,164 genes are organized in 381 operons. …”
Publicado 2015
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1013“…RESULTS: In the genome of S. tsukubaensis we have identified two ccr homologues; ccr1 is located in the putative ethylmalonyl-CoA (emc) operon and allR is located on the left fringe of the FK506 cluster. …”
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1014por Périchon, Bruno, Szili, Noémi, du Merle, Laurence, Rosinski-Chupin, Isabelle, Gominet, Myriam, Bellais, Samuel, Poyart, Claire, Trieu-Cuot, Patrick, Dramsi, Shaynoor“…We showed that the hairpin sequence located between antigen B and PI-2b operons is a transcriptional terminator. In A909, increased expression of PI-2b probably results from read-through transcription from antigen B operon. …”
Publicado 2017
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1015por Ormsby, Michael J., Logan, Michael, Johnson, Síle A., McIntosh, Anne, Fallata, Ghaith, Papadopoulou, Rodanthi, Papachristou, Eleftheria, Hold, Georgina L., Hansen, Richard, Ijaz, Umer Z., Russell, Richard K., Gerasimidis, Konstantinos, Wall, Daniel M.“…Finally, qRT-PCR indicated that expression of the E. coli eut operon was increased in children with active CD compared to healthy controls (fold change increase: >4.72; P < .02). …”
Publicado 2019
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1016por Schaffert, Lena, Schneiker-Bekel, Susanne, Dymek, Saskia, Droste, Julian, Persicke, Marcus, Busche, Tobias, Brandt, David, Pühler, Alfred, Kalinowski, Jörn“…Transcription of the aml operon is significantly repressed in the wild type when growing on glucose and repression is absent in an ΔamlR deletion mutant. …”
Publicado 2019
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1017por Crosby, Francy L., Munderloh, Ulrike G., Nelson, Curtis M., Herron, Michael J., Lundgren, Anna M., Xiao, Yu-Ping, Allred, David R., Barbet, Anthony F.“…Analysis of an A. phagocytophilum mutant carrying the Himar1 transposon within the virB6-4 gene demonstrated that the insertion not only disrupted its expression but also exerted a polar effect on the sodB-virB operon. Moreover, the altered expression of genes within this operon was associated with the attenuated in vitro growth of A. phagocytophilum in human and tick cells, indicating the importance of these genes in the physiology of this obligate intracellular bacterium in such different environments. …”
Publicado 2020
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1018por Rodionova, Irina A., Gao, Ye, Monk, Jonathan, Hefner, Ying, Wong, Nicholas, Szubin, Richard, Lim, Hyun Gyu, Rodionov, Dmitry A., Zhang, Zhongge, Saier, Milton H., Palsson, Bernhard O.“…CitR is a repressor of the ybdNM operon and is implicated in the regulation of citrate lyase genes (citCDEFG); (2) YgfI (tentatively re-named DhfA) activates the dhaKLM operon that encodes the phosphotransferase system, DhfA is involved in formate, glycerol and dihydroxyacetone utilization; (3) YiaU (tentatively re-named LpsR) regulates the yiaT gene encoding an outer membrane protein, and waaPSBOJYZU operon is also important in determining cell density at the stationary phase and resistance to oxacillin microaerobically; (4) YneJ, re-named here as PtrR, directly regulates the expression of the succinate-semialdehyde dehydrogenase, Sad (also known as YneI), and is a predicted regulator of fnrS (a small RNA molecule). …”
Publicado 2022
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1019“…Except for the glnRA and nif operon, the other 15 genes/operons are newly identified targets of GlnR. …”
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1020“…Further, the upregulation of three different esterases (estG2, estG3 and estG5), a phthalic acid (PA)-metabolizing pht operon and a protocatechuic acid (PCA)-metabolizing pca operon were revealed based on de novo whole genome sequence information and substrate-induced protein profiling by LC-ESI-MS/MS analysis followed by differential gene expression by real-time PCR. …”
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