Clinical and pathological features associated with circulating tumor DNA content in real‐world patients with metastatic prostate cancer

por Antonarakis, Emmanuel S., Tierno, Marni, Fisher, Virginia, Tukachinsky, Hanna, Alexander, Sonja, Hamdani, Omar, Hiemenz, Matthew C., Huang, Richard S.P., Oxnard, Geoffrey R., Graf, Ryon P.
Publicado 2022

Complementary Roles for Tissue- and Blood-Based Comprehensive Genomic Profiling for Detection of Actionable Driver Alterations in Advanced NSCLC

por Schwartzberg, Lee S., Li, Gerald, Tolba, Khaled, Bourla, Ariel B., Schulze, Katja, Gadgil, Rujuta, Fine, Alexander, Lofgren, Katherine T., Graf, Ryon P., Oxnard, Geoffrey R., Daniel, Davey
Publicado 2022

Potential pathogenic germline variant reporting from tumor comprehensive genomic profiling complements classic approaches to germline testing

por Tung, Nadine, Dougherty, Kali Chatham, Gatof, Emily Stern, DeLeonardis, Kim, Hogan, Lauren, Tukachinsky, Hanna, Gornstein, Erica, Oxnard, Geoffrey R., McGregor, Kimberly, Keller, Rachel B.
Publicado 2023

Genomic Evolution in a Patient With Lung Adenocarcinoma With a Germline EGFR T790M Mutation

por Mäkinen, Netta, Zhou, Meng, Bemus, Meredith, Nevin, Julius, Nag, Anwesha, Chen, Ruthia, Colson, Yolonda L., Thorner, Aaron R., Oxnard, Geoffrey R., Meyerson, Matthew, Sholl, Lynette M.
Publicado 2021

Biology and Targetability of the Extended Spectrum of PIK3CA Mutations Detected in Breast Carcinoma

por Rugo, Hope S., Raskina, Kira, Schrock, Alexa B., Madison, Russell W., Graf, Ryon P., Sokol, Ethan S., Sivakumar, Smruthy, Lee, Jessica K., Fisher, Virginia, Oxnard, Geoffrey R., Tukachinsky, Hanna
Publicado 2023

Genomic landscape of 891 RET fusions detected across diverse solid tumor types

por Parimi, Vamsi, Tolba, Khaled, Danziger, Natalie, Kuang, Zheng, Sun, Daokun, Lin, Douglas I., Hiemenz, Matthew C., Schrock, Alexa B., Ross, Jeffrey S., Oxnard, Geoffrey R., Huang, Richard S. P.
Publicado 2023

ERBB2 Copy Number as a Quantitative Biomarker for Real-World Outcomes to Anti–Human Epidermal Growth Factor Receptor 2 Therapy in Advanced Gastroesophageal Adenocarcinoma

por Zhang, Liangliang, Hamdani, Omar, Gjoerup, Ole, Cho-Phan, Cheryl, Snider, Jeremy, Castellanos, Emily, Nimeiri, Halla, Frampton, Garrett, Venstrom, Jeffrey M., Oxnard, Geoffrey, Klempner, Samuel J., Schrock, Alexa B.
Publicado 2022

Durable responders in advanced NSCLC with elevated TMB and treated with 1L immune checkpoint inhibitor: a real-world outcomes analysis

por Huang, Richard S P, Carbone, David P, Li, Gerald, Schrock, Alexa, Graf, Ryon P, Zhang, Liangliang, Murugesan, Karthikeyan, Ross, Jeffrey S, Tolba, Khaled, Sands, Jacob, Oxnard, Geoffrey R, Spigel, David
Publicado 2023

Savolitinib ± Osimertinib in Japanese Patients with Advanced Solid Malignancies or EGFRm NSCLC: Ph1b TATTON Part C

por Yoh, Kiyotaka, Hirashima, Tomonori, Saka, Hideo, Kurata, Takayasu, Ohe, Yuichiro, Hida, Toyoaki, Mellemgaard, Anders, Verheijen, Remy B., Ou, Xiaoling, Ahmed, Ghada F., Hayama, Manabu, Sugibayashi, Ko, Oxnard, Geoffrey R.
Publicado 2021

Characterization of Non–Small-Cell Lung Cancers With MET Exon 14 Skipping Alterations Detected in Tissue or Liquid: Clinicogenomics and Real-World Treatment Patterns

por Lee, Jessica K., Madison, Russell, Classon, Anthony, Gjoerup, Ole, Rosenzweig, Mark, Frampton, Garrett M., Alexander, Brian M., Oxnard, Geoffrey R., Venstrom, Jeffrey M., Awad, Mark M., Schrock, Alexa B.
Publicado 2021

Prognostic value of plasma circulating tumor DNA fraction across four common cancer types: a real-world outcomes study()

por Reichert, Z. R., Morgan, T. M., Li, G., Castellanos, E., Snow, T., Dall’Olio, F. G., Madison, R. W., Fine, A. D., Oxnard, G. R., Graf, R. P., Stover, D. G.
Publicado 2023

Evaluation of tissue- and plasma-derived tumor mutational burden (TMB) and genomic alterations of interest in CheckMate 848, a study of nivolumab combined with ipilimumab and nivol...

por He, Jie, Kalinava, Natallia, Doshi, Parul, Pavlick, Dean C, Albacker, Lee A, Ebot, Ericka M, Tukachinsky, Hanna, Pratt, James, Fusaro, Gina, Oxnard, Geoffrey R, Green, George, Fabrizio, David, Baden, Jonathan
Publicado 2023

The Pan-Tumor Landscape of Targetable Kinase Fusions in Circulating Tumor DNA

por Lee, Jessica K., Hazar-Rethinam, Mehlika, Decker, Brennan, Gjoerup, Ole, Madison, Russell W., Lieber, Daniel S., Chung, Jon H., Schrock, Alexa B., Creeden, James, Venstrom, Jeffrey, Alexander, Brian, Oxnard, Geoffrey R.
Publicado 2022

Unique Spectrum of Activating BRAF Alterations in Prostate Cancer

por Chehrazi-Raffle, Alex, Tukachinsky, Hanna, Toye, Eamon, Sivakumar, Smruthy, Schrock, Alexa B., Bergom, Hannah E., Ebrahimi, Hedyeh, Pal, Sumanta, Dorff, Tanya, Agarwal, Neeraj, Mahal, Brandon A., Oxnard, Geoffrey R., Hwang, Justin, Antonarakis, Emmanuel S.
Publicado 2023

Tumor Mutational Burden in Real-World Patients With Pancreatic Cancer: Genomic Alterations and Predictive Value for Immune Checkpoint Inhibitor Effectiveness

por Quintanilha, Julia C.F., Storandt, Michael H., Graf, Ryon P., Li, Gerald, Keller, Rachel, Lin, Douglas I., Ross, Jeffrey S., Huang, Richard S.P., Schrock, Alexa B., Oxnard, Geoffrey R., Chakrabarti, Sakti, Mahipal, Amit
Publicado 2023

Comparative Effectiveness of Immune Checkpoint Inhibitors vs Chemotherapy in Patients With Metastatic Colorectal Cancer With Measures of Microsatellite Instability, Mismatch Repair...

por Quintanilha, Julia C. F., Graf, Ryon P., Fisher, Virginia A., Oxnard, Geoffrey R., Ellis, Haley, Panarelli, Nicole, Lin, Douglas I., Li, Gerald, Huang, Richard S. P., Ross, Jeffrey S., Myer, Parvathi A., Klempner, Samuel J.
Publicado 2023

Homologous Recombination Deficiency Landscape of Breast Cancers and Real-World Effectiveness of Poly ADP-Ribose Polymerase Inhibitors in Patients With Somatic BRCA1/2, Germline PAL...

por Batalini, Felipe, Madison, Russell W., Sokol, Ethan S., Jin, Dexter X., Chen, Kuei-Ting, Decker, Brennan, Pavlick, Dean C., Frampton, Garrett M., Wulf, Gerburg M., Garber, Judy E., Oxnard, Geoffrey, Schrock, Alexa B., Tung, Nadine M.
Publicado 2023

Mindfulness Training for Primary Care for Portuguese-Speaking Immigrants: A Pilot Study

por Trombka, Marcelo, Creedon, Timothy B., Demarzo, Marcelo, Cuoco, Letícia T., Smith, Lydia, Oxnard, Alexandra C., Rozembaque, Alana T., Hirayama, Marcio S., Moreno, Natalia B., Comeau, Alexandra, Gawande, Richa, Griswold, Todd, Cook, Benjamin L., Rocha, Neusa S., Schuman-Olivier, Zev
Publicado 2021

Brief Report: Safety and Antitumor Activity of Alectinib Plus Atezolizumab From a Phase 1b Study in Advanced ALK-Positive NSCLC

por Kim, Dong-Wan, Gadgeel, Shirish, Gettinger, Scott N., Riely, Gregory J., Oxnard, Geoffrey R., Mekhail, Tarek, Schmid, Peter, Dowlati, Afshin, Heist, Rebecca S., Wozniak, Antoinette J., Singh, Jatinder, Cha, Edward, Spahn, Jessica, Ou, Sai-Hong Ignatius
Publicado 2022

The Genomics of Young Lung Cancer: Comprehensive Tissue Genomic Analysis in Patients Under 40 With Lung Cancer

por Gitlitz, Barbara J., Novello, Silvia, Vavalà, Tiziana, Bittoni, Marisa, Sable-Hunt, Alicia, Pavlick, Dean, Hsu, Robert, Park, S. Lani, Chen, Ruthia, Cooke, Matthew, Moore, Amy, Schrock, Alexa B., Schiller, Joan H., Addario, Bonnie J., Oxnard, Geoffrey R.
Publicado 2021