“…A recent discovery in PLOS Biology shows that chaperone Hsp42 plays a crucial role in resolubilizing the proteome during dormancy breaking, although a role of trehalose cannot be excluded.…”
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“…Why do adult mammalian central nervous system axons not regenerate, when peripheral axons do? Two studies in PLOS Biology point to the role of 2 related ribosomal S6 kinase family members in the differences in regeneration capacity between central and peripheral axons.…”
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“…A new study in this issue of PLOS Biology reveals recent evolutionary losses of key piRNA biogenesis factors in flies, highlighting adaptability by rapid shift to alternative piRNA biogenesis strategies.…”
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“…Our current understanding of early human development is limited. A study in PLOS Biology found a previously undefined group of cells that diverges from the main lineages and undergo apoptosis through the activity of young transposable elements.…”
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“…Here, we discuss the implications of a 2010 PLOS Biology paper that shed light on the functional importance of PINK1 in the mitophagy cascade.…”
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“…Microglia play a dual role in stroke depending on their pro-inflammatory and anti-inflammatory polarization. A study in PLOS Biology identifies a new mechanism, through which the transcription factor NR4A1 negatively regulates TNF expression in microglia.…”
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“…In 2018, PLOS Biology announced CellProfiler 3.0, which has become one of the most used pieces of image analysis software in biology. …”
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“…Pioneering work in plants, published in PLOS Biology almost 20 years ago, established a framework to understand how multiple RNA interference pathways can regulate the genome in parallel.…”
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“…Several dietary components disrupt the control of energy balance. A new study in PLOS Biology shows that, in mice, maternal consumption of emulsifiers induces a rewiring of the hypothalamic feeding circuits and causes neuropsychological impairment in the offspring.…”
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“…According to a new study in this issue of PLOS Biology, the virulence of a zoonotic virus in humans depends on its reservoir host. …”
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“…Theory predicts that temperature fluctuations should reduce performance near an organism’s thermal optimum. A new study in PLOS Biology found fluctuations increased parasite transmission instead, highlighting questions about how climate change will impact infectious diseases.…”
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“…The mechanistic underpinnings of breast cancer recurrence following periods of dormancy are largely undetermined. A new study in PLOS Biology reveals that docetaxel-induced injury of tumour stromal cells stimulates the release of cytokines that support dormancy escape of breast cancer cells.…”
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“…A new study published in PLOS Biology finds that the SCO responds to glucose by secreting signaling molecules into the cerebrospinal fluid (CSF), thereby decreasing the local ependyma-driven CSF movement.…”
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“…A study published in PLOS Biology finds a different pattern—60 SNPs spread across the genome differentiate a Penstemon species pair.…”
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“…A 2008 article in PLOS Biology reported a senescence-associated secretory phenotype that can promote inflammation and cancer, eventually enabling the development of senolytic drugs.…”
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“…A new evolutionary model of mate choice copying, published in PLOS Biology, aims to reconcile mismatches between theory and data by proposing that juvenile females mistakenly imprint on male phenotypes that were not in fact preferred by the female they copied.…”
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“…A recent study in PLOS Biology assesses changes in the use of data analysis techniques over time to determine which skills young scientists might need.…”
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“…What is their source, and why are they so abundant? A new study in PLOS Biology supports a classic model of transposon origins.…”
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“…A study in this issue of PLOS Biology revealed that Aβ from the liver can promote brain pathology, supporting that peripheral Aβ can contribute to neurodegeneration.…”
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“…Memory performance is crucial across the human life, from early education to age-related decline. A new study in PLOS Biology found that verbal learning can be enhanced by applying repetitive transcranial magnetic stimulation (rTMS) over the left prefrontal cortex.…”
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