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541por Pimkhaokham, Atiphan, Jiaranuchart, Sirimanas, Kaboosaya, Boosana, Arunjaroensuk, Sirida, Subbalekha, Keskanya, Mattheos, NikosEnlace del recurso
Publicado 2022
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542por Quaranta, Alessandro, D'Isidoro, Orlando, Piattelli, Adriano, Hui, Wang Lai, Perrotti, VittoriaEnlace del recurso
Publicado 2022
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543por Breugelmans, J. Gabrielle, Makanga, Michael M., Cardoso, Ana Lúcia V., Mathewson, Sophie B., Sheridan-Jones, Bethan R., Gurney, Karen A., Mgone, Charles S.“…Both regions contributed more to the global research output in malaria (43.4% and 22.2%, respectively). The overall number of PRD papers from sub-Saharan Africa increased markedly (>47%) since 2003, particularly for HIV/AIDS (102%) and tuberculosis (TB) (81%), and principally involving Southern and East Africa. …”
Publicado 2015
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544por Patel, Anamika, Horton, John R., Wilson, Geoffrey G., Zhang, Xing, Cheng, Xiaodong“…The multidomain zinc finger (ZnF) protein PRDM9 (PRD1–BF1–RIZ1 homologous domain-containing 9) is thought to influence the locations of recombination hot spots during meiosis by sequence-specific DNA binding and trimethylation of histone H3 Lys4. …”
Publicado 2016
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545por Enders, Felicitas Bellutti, Bader-Meunier, Brigitte, Baildam, Eileen, Constantin, Tamas, Dolezalova, Pavla, Feldman, Brian M, Lahdenne, Pekka, Magnusson, Bo, Nistala, Kiran, Ozen, Seza, Pilkington, Clarissa, Ravelli, Angelo, Russo, Ricardo, Uziel, Yosef, van Brussel, Marco, van der Net, Janjaap, Vastert, Sebastiaan, Wedderburn, Lucy R, Wulffraat, Nicolaas, McCann, Liza J, van Royen-Kerkhof, Annet“…CONCLUSIONS: The SHARE initiative aims to identify best practices for treatment of patients suffering from PRD. Within this remit, recommendations for the diagnosis and treatment of JDM have been formulated by an evidence-informed consensus process to produce a standard of care for patients with JDM throughout Europe.…”
Publicado 2017
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546por Capilla-Perez, Laia, Solier, Victor, Portemer, Virginie, Chambon, Aurelie, Hurel, Aurelie, Guillebaux, Alexia, Vezon, Daniel, Cromer, Laurence, Grelon, Mathilde, Mercier, Raphael“…Of these, 21 lines had an obvious candidate causal mutation, namely a STOP or splicing site mutation in a gene previously shown to play a role in meiosis (ATM, MLH3, MLH1, MER3, HEI10, FLIP, ASY4, FLIP, PRD2, REC8, FANCL, and PSS1). Interestingly, this was the first time that six of these genes were identified in a forward screen in Arabidopsis (MLH3, MLH1, SGO1, PSS1, FANCL, and ASY4). …”
Publicado 2018
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547por Seear, Paul J., France, Martin G., Gregory, Catherine L., Heavens, Darren, Schmickl, Roswitha, Yant, Levi, Higgins, James D.“…Individual plants were genotyped by high-throughput sequencing of the eight meiosis genes (ASY1, ASY3, PDS5b, PRD3, REC8, SMC3, ZYP1a/b) implicated in synaptonemal complex formation and phenotyped by assessing meiotic metaphase I chromosome configurations. …”
Publicado 2020
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548por Mäki-Heikkilä, Rikhard, Karjalainen, Jussi, Parkkari, Jari, Valtonen, Maarit, Lehtimäki, Lauri“…Future research should investigate how the intensity of training, airway infections and their treatment affect the development of asthma among skiers. PRD REGISTRATION NUMBER: CRD42017070940. ELECTRONIC SUPPLEMENTARY MATERIAL: The online version of this article (10.1007/s40279-020-01334-4) contains supplementary material, which is available to authorized users.…”
Publicado 2020
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549por Rojas Flores, Georgina“…The reflections that the reader will find in this book published by UNAM-Gernika refer to the period 2000-2015, when in the Mexican capital a hegemony of local delegational governments from the Party of the Democratic Revolution (PRD) still prevailed.Keywords: Local democracy, Quality of democracy, Mexico City, Social policy and delegations Démocratie locale à la Ville de México : l’expérience des organes des délégations municipalesResuméFrancisco Reveles Vázquez (coord.) (2018) réunit une diversité de perspectives spécialisées dans des thèmes politiques et sociaux sur les apports des gouvernements des délégations municipales de la Ville de Mexico sur la démocratie locale à la recherche de l’égalité sociale dans ses territoires. …”
Publicado 2021
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550por Recinella, Lucia, De Filippis, Barbara, Libero, Maria Loreta, Ammazzalorso, Alessandra, Chiavaroli, Annalisa, Orlando, Giustino, Ferrante, Claudio, Giampietro, Letizia, Veschi, Serena, Cama, Alessandro, Mannino, Federica, Gasparo, Irene, Bitto, Alessandra, Amoroso, Rosa, Brunetti, Luigi, Leone, Sheila“…Compared to the control, 1a stimulated uncoupling protein 1 (UCP1), PR-(PRD1-BF1-RIZ1 homologous) domain containing 16 (PRDM16), deiodinase type II (DIO2), and PPARα and PPARγ gene expression, in 3T3-L1 cells. …”
Publicado 2023
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551“…This adaptation resulted in the exapted evolution of resistance against a plasmid-dependent bacteriophage PRD1. Further, previous studies have suggested that mutations in this region completely abolish the plasmid’s ability to conjugate; however, our study shows it is not essential for conjugation but rather affects the host-specific conjugation efficiency. …”
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552“…RESULTS: An average transformation frequency and Bt-Cry protein content of 16.93 ± 2.10 and 0.0020–0.0128% of total soluble protein (TSP) was obtained with pRD400 vector (Trcry1Ac) while, a much lower value of 9.30 ± 2.041 and 0.0001 ― 0.0026% of TSP was observed with pNBRI-1 vector (Flcry1Ac), respectively. …”
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553“…We also use these data to compare expression specificity between evolutionarily-based gene classes, revealing that ANTP, PRD, LIM and POU homeobox gene classes have highest tissue specificity while HNF, TALE, CUT and CERS are most widely expressed. …”
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554por Yang, Chaohua, Yu, Baoqing, Ma, Fenfen, Lu, Huiping, Huang, Jianmin, You, Qinghua, Yu, Bin, Qiao, Jianlan, Feng, Jianjun“…RESULTS: The behavioral test results and onset latency of the SEPs indicated that there were significant differences between priority rostral decompression (PRD) and priority caudal decompression (PCD) in the 50-μl compression group at 6 weeks post-injury; however, there were no significant differences between the two procedures in the 40-μl group at the same time point. …”
Publicado 2017
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555por Kodo, Kazuki, Sugimoto, Satoru, Nakajima, Hisakazu, Mori, Jun, Itoh, Ikuyo, Fukuhara, Shota, Shigehara, Keiichi, Nishikawa, Taichiro, Kosaka, Kitaro, Hosoi, Hajime“…EPO significantly upregulated the PRD1-BF1-RIZ1 homologous domain containing 16 (PRDM16), a transcriptional factor with a crucial role in brown adipocyte differentiation. …”
Publicado 2017
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556por Wang, Yinyu, Mao, Yiting, Zhao, Yiran, Yi, Xianfu, Ding, Guolian, Yu, Chuanjin, Sheng, Jianzhong, Liu, Xinmei, Meng, Yicong, Huang, Hefeng“…BACKGROUND: Maternal protein restriction diet (PRD) increases the risk of metabolic dysfunction in adulthood, the mechanisms during the early life of offspring are still poorly understood. …”
Publicado 2021
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558por Verrest, Luka, Wilthagen, Erica A., Beijnen, Jos H., Huitema, Alwin D. R., Dorlo, Thomas P. C.“…METHODS: A systematic review was performed on the effects of malnourishment on the pharmacokinetics of drugs to treat PRDs, including HIV, tuberculosis, malaria, and neglected tropical diseases. RESULTS: In 21/29 PRD drugs included in this review, pharmacokinetics were affected by malnutrition. …”
Publicado 2021
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559por Liu, Qian, Lin, Jing, Wen, Li, Wang, Shaozhou, Zhou, Peng, Mei, Li, Shang, Shuyong“…In addition, the arbitrary BLUs used to characterize DPI affinity values were measured via an indirect approach, which may not very reliable and may involve strong noise, thus leading to a considerable bias in the modeling. The R ( prd ) (2) = 0.7 can be considered as the upper limit of external generalization ability of the pQSAR methodology working on large-scale DPI affinity data.…”
Publicado 2022
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560por Dong, Liang, Liu, Xinning, Wu, Bo, Li, Chengwei, Wei, Xiaomin, Wumaier, Gulinuer, Zhang, Xiujuan, Wang, Jing, Xia, Jingwen, Zhang, Yuanyuan, Yiminniyaze, Ruzetuoheti, Zhu, Ning, Li, Jing, Zhou, Daibing, Zhang, Youzhi, Li, Shuanghui, Lv, Junzhu, Li, Shengqing“…Although it also binds to Max, Mxi1-0, unlike other Mxi1 isoforms, cannot antagonize the oncoprotein c-Myc because of its unique proline rich domain (PRD). While Mxi1-0 was reported to promote cell proliferation via largely uncharacterized mechanisms, it is unknown whether and how it plays a role in the pathogenesis of HPH. …”
Publicado 2022
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