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  1. 441
    “…Sulfonylurea did not change both plasma t-PA and PAI-1 antigen levels. In conclusion, diabetic patients have high t-PA and PAI-1 antigen levels. …”
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    Plasma t-PA and PAI-1 Antigen Concentrations in Non-Insulin Dependent Diabetic Patients: Effects of Treatment Modality on Fibrinolysis
  2. 442
    “…METHODS: The aim of the current study was to explore the association between the variants in PAI-2 gene and CAD and its prognoses. The three variants (rs8093048, rs9946657, rs9320032) of the PAI-2 gene were detected in 407 patients with CAD and 518 control subjects. …”
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    Variant of PAI-2 gene is associated with coronary artery disease and recurrent coronary event risk in Chinese Han population
  3. 443
    “…The activation of potential PAI-1/LRP1 axis with purified PAI-1 promoted increased phosphorylation of STAT3 and subsequently exocytosis in MCs. …”
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    Glioma-derived plasminogen activator inhibitor-1 (PAI-1) regulates the recruitment of LRP1 positive mast cells
  4. 444
    “…Thrombin treatment induces the t-PA and PAI-1 release from HUVE cell line, and FA treatment was found to antagonize the thrombin induced t-PA and PAI-1 release. …”
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    Effect of Fagonia arabica on thrombin induced release of t-PA and complex of PAI-1 tPA in cultured HUVE cells
  5. 445
    “…BACKGROUND: Plasminogen activator inhibitor-1 (PAI-1) is induced in airways by virus and may mediate asthmatic airway remodeling. …”
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    Association of a PAI-1 Gene Polymorphism and Early Life Infections with Asthma Risk, Exacerbations, and Reduced Lung Function
  6. 446
    por Chen, Hsi-Chung, Chou, Pesus
    Publicado 2017
    “…A total of 2,294 participants over the age of 65 in the Shih-Pai Sleep Study were followed-up for an average of 3 years. …”
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    Predictors of Change in Self-Reported Sleep Duration in Community-Dwelling Older Adults: The Shih-Pai Sleep Study, Taiwan
  7. 447
    “…We have studied the dynamic preludes to conformational change in the serpin plasminogen activator inhibitor 1 (PAI-1). We report the first multi-microsecond atomistic molecular dynamics simulations of PAI-1 and compare the data with experimental hydrogen/deuterium-exchange data (HDXMS). …”
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    Conformational preludes to the latency transition in PAI-1 as determined by atomistic computer simulations and hydrogen/deuterium-exchange mass spectrometry
  8. 448
    “…In the present study, plasticity region genes (jhp0940, jhp0945 and jhp0947) and and cagE gene of cag PAI were assessed independently and in combination for their ability to predict clinical consequences. …”
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    Role of Plasticity Region Genes and cagE gene of cagPAI of Helicobacter pylori in Development of Gastrointestinal (GI) Diseases
  9. 449
    “…SDS-PAGE analysis showed that formation of the PAI-1/uPA complex was inhibited by loureirin B, and the inhibitory effect of loureirin B on PAI-1 was also confirmed by clot lysis assay. …”
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    Bioactivity-Guided Fractionation of the Traditional Chinese Medicine Resina Draconis Reveals Loureirin B as a PAI-1 Inhibitor
  10. 450
    “…Thus, overall, high expressions of MMP-2, RB and/or PAI-1 in bladder tumors were markers of poor prognosis. …”
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    Association of MMP-2, RB and PAI-1 with decreased recurrence-free survival and overall survival in bladder cancer patients
  11. 451
    “…We have generated a human induced pluripotent stem cell (iPSC) line under feeder-free culture conditions using the urine derived cells (UCs) collected from subjects heterozygous for a novel Plasminogen Activator Inhibitor-1 (PAI-1) mutation. The Sendai Virus (SeV) vector encoding pluripotent Yamanaka transcription factors was used at a low multiplicity of infection to reprogram the PAI-1 UCs.…”
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    Generation of human iPSCs from urine derived cells of patient with a novel heterozygous PAI-1 mutation
  12. 452
    “…Functional assays showed that PAI‐1 and CCL5 overexpression promoted cell proliferation and migration in breast cancer cells, while inhibition of PAI‐1 and CCL5 decreased cell proliferation and migration in saracatinib‐resistant cells. …”
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    PAI‐1 induces Src inhibitor resistance via CCL5 in HER2‐positive breast cancer cells
  13. 453
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    Sou homem e pai sim! (Re)construindo a identidade masculina a partir da participação no parto
  14. 454
    “…To investigate cellular PAI‐1 expression and its correlation with α‐SMA expression of CAFs, 34 patients’ paraffin‐embedded lung adenocarcinoma tissue sections were immunohistochemically stained for PAI‐1 and α‐SMA. …”
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    Inhibition of PAI‐1 limits chemotherapy resistance in lung cancer through suppressing myofibroblast characteristics of cancer‐associated fibroblasts
  15. 455
    “…Plasminogen activator inhibitor 1 (PAI-1) is a member of the serpin family of proteases that inhibits tissue-type plasminogen activator and urokinase. …”
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    OR22-6 Reversal Of Diet Induced Metabolic Syndrome In Mice With An Orally Active Small Molecule Inhibitor Of PAI-1
  16. 456
    “…BACKGROUND: To conduct a comprehensive performance evaluation of a fully automated analyzer for measuring thrombomodulin (TM), thrombin‐antithrombin complex (TAT), plasmin‐α2‐antiplasmin complex (PAP), and t‐PA: PAI‐1 complex (tPAI‐C). METHODS: According to the Clinical and Laboratory Standards Institute (CLSI) EP05‐A2, EP06‐A specifications, TM, TAT, PAP, and tPAI‐C were analyzed to evaluate intraassay variability and interassay variability, linear range, carryover rate, reference range, sample stability, and interferences. …”
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    Performance evaluation of thrombomodulin, thrombin‐antithrombin complex, plasmin‐α2‐antiplasmin complex, and t‐PA: PAI‐1 complex
  17. 457
    “…METHODS: Twenty‐one carers of people with Parkinson's disease from a Primary Care practice in Spain were recruited and completed the PAIS‐Carers, the SF‐36 Health Survey, the Brief COPE Inventory and an assessment form. …”
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    A pilot study on the Spanish version of the Psychosocial Adjustment to Illness Scale (PAIS‐SR) with carers of people with Parkinson's disease
  18. 458
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    Impacto de la identificación de pacientes en un programa de cuidados paliativos del País Vasco
  19. 459
    “…Here we aimed to investigate the role of plasminogen activator inhibitor‐1 (PAI‐1), an effective inhibitor of t‐PA, and its major polymorphism (PAI‐1 4G/5G) in therapy outcome. …”
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    PAI‐1 5G/5G genotype is an independent risk of intracranial hemorrhage in post‐lysis stroke patients
  20. 460
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    Estratificación de la población en el País Vasco: resultados en el primer año de implantación()
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