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  1. 105821
    “…He was diagnosed with psoriatic arthritis (PsA) at age 47 and plaque psoriasis at 20. He has no other past medical history. For PsA, he was initially treated with Methotrexate, but this was stopped due to nausea. …”
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    EP19 Renal sarcoidosis associated with certolizumab pegol treatment for psoriatic arthritis: a case report
  2. 105822
    “…CASE REPORT - CASE DESCRIPTION: A 54-year-old Middle Eastern woman presented to A&E with a one-week history of fever, cough, headache and ageusia. Her past medical history was significant for asthma, chronic headaches, gastro-oesophageal reflux syndrome and subarachnoid haemorrhage. …”
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    O03 A case of hyperinflammatory COVID-19 that responded to tocilizumab therapy
  3. 105823
    por Chen-Xu, Michael, Sykes, Mark
    Publicado 2020
    “…Her Sjögren’s syndrome was diagnosed after she presented with difficult sicca symptoms, fatigue and Raynaud’s phenomenon, and strongly positive ANA and anti-Ro antibodies (>240 u/mL). Past medical history was notable for microscopic colitis. …”
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    EP35 Cryoglobulinaemic vasculitis: an uncommon complication of Sjögren’s syndrome
  4. 105824
    “…METHODS: Hospitalized patients with oxygen saturation ≤94%, a positive SARS-CoV-2 PCR in the past 4 days and radiographic evidence of pneumonia were randomized 1:1 to receive 5d or 10d of intravenous RDV. …”
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    73. Geographical Disparities in Clinical Outcomes of Severe COVID-19 Patients Treated with Remdesivir
  5. 105825
    “…In the phase 2b trial, patients were aged 65–85 years, with asthma, type 2 diabetes, chronic obstructive pulmonary disease (COPD), congestive heart failure, were current smokers, or had an emergency room or hospitalisation for an RTI within the past 12 months. In the phase 3 trial, patients were aged at least 65 years, did not have COPD, and were not current smokers. …”
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    Targeting the biology of ageing with mTOR inhibitors to improve immune function in older adults: phase 2b and phase 3 randomised trials
  6. 105826
    “…HIV), diabetes mellitus, active pulmonary tuberculosis, past history of any chronic respiratory disease, motor neuron disease, multiple sclerosis, stroke, impaired cognition, atrial fibrillation, acute coronary syndrome, myocardial infarction, severe arrhythmia, concurrent serious hepatic disease or renal disease, pregnant or lactating women, patients on immunosuppressive medications, history of hypersensitivity to the trial drugs or their ingredients, depressive illness (before COVID-19), diagnosed psychotic illnesses, substance dependence or alcoholism will be excluded. …”
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    Safety and efficacy of Ayurvedic interventions and Yoga on long term effects of COVID-19: A structured summary of a study protocol for a randomized controlled trial
  7. 105827
    “…Patient # 3 A 22-yr-old lady with past H/O AML t(8;21) was admitted on April 27, 2014 with 3 day H/O cough, fever & SOB. …”
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    Report of Middle East Respiratory Syndrome Coronavirus (MERS-CoV) Infection in Four Patients with Hematological Malignancies Treated at King Fahad Medical City, Riyadh, Saudi Arabia
  8. 105828
    por van der Pluijm, Rob W, Tripura, Rupam, Hoglund, Richard M, Pyae Phyo, Aung, Lek, Dysoley, ul Islam, Akhter, Anvikar, Anupkumar R, Satpathi, Parthasarathi, Satpathi, Sanghamitra, Behera, Prativa Kumari, Tripura, Amar, Baidya, Subrata, Onyamboko, Marie, Chau, Nguyen Hoang, Sovann, Yok, Suon, Seila, Sreng, Sokunthea, Mao, Sivanna, Oun, Savuth, Yen, Sovannary, Amaratunga, Chanaki, Chutasmit, Kitipumi, Saelow, Chalermpon, Runcharern, Ratchadaporn, Kaewmok, Weerayuth, Hoa, Nhu Thi, Thanh, Ngo Viet, Hanboonkunupakarn, Borimas, Callery, James J, Mohanty, Akshaya Kumar, Heaton, James, Thant, Myo, Gantait, Kripasindhu, Ghosh, Tarapada, Amato, Roberto, Pearson, Richard D, Jacob, Christopher G, Gonçalves, Sónia, Mukaka, Mavuto, Waithira, Naomi, Woodrow, Charles J, Grobusch, Martin P, van Vugt, Michele, Fairhurst, Rick M, Cheah, Phaik Yeong, Peto, Thomas J, von Seidlein, Lorenz, Dhorda, Mehul, Maude, Richard J, Winterberg, Markus, Thuy-Nhien, Nguyen Thanh, Kwiatkowski, Dominic P, Imwong, Mallika, Jittamala, Podjanee, Lin, Khin, Hlaing, Tin Maung, Chotivanich, Kesinee, Huy, Rekol, Fanello, Caterina, Ashley, Elizabeth, Mayxay, Mayfong, Newton, Paul N, Hien, Tran Tinh, Valecha, Neena, Smithuis, Frank, Pukrittayakamee, Sasithon, Faiz, Abul, Miotto, Olivo, Tarning, Joel, Day, Nicholas P J, White, Nicholas J, Dondorp, Arjen M
    Publicado 2020
    “…Eligible patients were aged 2–65 years, with acute, uncomplicated P falciparum malaria alone or mixed with non-falciparum species, and a temperature of 37·5°C or higher, or a history of fever in the past 24 h. Patients were randomly assigned (1:1) to one of two treatments using block randomisation, depending on their location: in Thailand, Cambodia, Vietnam, and Myanmar patients were assigned to either dihydroartemisinin–piperaquine or dihydroartemisinin–piperaquine plus mefloquine; at three sites in Cambodia they were assigned to either artesunate–mefloquine or dihydroartemisinin–piperaquine plus mefloquine; and in Laos, Myanmar, Bangladesh, India, and the Democratic Republic of the Congo they were assigned to either artemether–lumefantrine or artemether–lumefantrine plus amodiaquine. …”
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    Triple artemisinin-based combination therapies versus artemisinin-based combination therapies for uncomplicated Plasmodium falciparum malaria: a multicentre, open-label, randomised clinical trial
  9. 105829
    “…Patients with documented significant liver disease/dysfunction (AST/ALT > 240), myopathy and rhabdomyolysis (CPK > 5x normal), allergy or intolerance to statins, allergy or intolerance to aspirin, patients taking medications with significant interaction with statins, prior statin use (within 30 days), prior aspirin use (within 30 days), history of active GI bleeding in past three months, coagulopathy, thrombocytopenia (platelet count < 100000/ dl), pregnancy, active breastfeeding, patient unable to take oral or nasogastric medications, patients in altered mental status, shock, acute renal failure, acute coronary syndrome, sepsis and ARDS at presentation will be excluded. …”
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    A randomized open-label trial to evaluate the efficacy and safety of triple therapy with aspirin, atorvastatin, and nicorandil in hospitalised patients with SARS Cov-2 infection: A structured summary of a study protocol for a randomized controlled trial
  10. 105830
    “…OBJECTIVES: Over the past decade, there have been advances in arthroscopic-assisted approaches for coracoclavicular (CC) reconstruction with less surgical morbidity and enhanced visualization while also allowing for the treatment of concomitant glenohumeral pathology. …”
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    Arthroscopic-Assisted Coracoclavicular Ligament Reconstruction: Clinical Outcomes and Return to Activity at Mean Six-Year Follow-up
  11. 105831
    por Chan, Antoni, Sacks, Sarah
    Publicado 2021
    “…She had radiographic axSpA (ankylosing spondylitis) for 6 years and was HLA-B27 positive. Her past medical history included hypertension which was treated with amlodipine and ramipril. …”
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    O27 Recurrent severe uveitis treated with secukinumab following anti-TNF induced cutaneous vasculitis in a patient with axial spondyloarthritis
  12. 105832
    “…Medical history includes systemic hypertension, hypothyroidism and hyperlipidaemia, no past ocular history. Eye examination was normal except decompensated fourth nerve paresis. …”
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    O31 Giant cell arteritis - a rare ocular presentation
  13. 105833
    “…Bivariate analysis shows that gender (female, P=0.04), past stroke/transient ischemic attack (P=0.04), deep venous thrombosis (P=0.02), abnormal kidney function (P=0.01) associate with PCS. …”
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    289. Post COVID Syndrome Cohort Characterization
  14. 105834
    “…Porter:  ASH: Membership on an entity's Board of Directors or advisory committees; Incyte: Membership on an entity's Board of Directors or advisory committees; DeCart: Membership on an entity's Board of Directors or advisory committees; Genentech: Current equity holder in publicly-traded company, Ended employment in the past 24 months; American Society for Transplantation and Cellular Therapy: Honoraria; Kite/Gilead: Membership on an entity's Board of Directors or advisory committees; Janssen: Membership on an entity's Board of Directors or advisory committees; National Marrow Donor Program: Membership on an entity's Board of Directors or advisory committees; Novartis: Membership on an entity's Board of Directors or advisory committees, Patents & Royalties, Research Funding; Tmunity: Patents & Royalties; Wiley and Sons Publishing: Honoraria. …”
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    Incidence and Predictors of Sars-Cov-2 Antibody Responses Following COVID-19 Vaccination in Allogeneic Stem Cell Transplant Recipients
  15. 105835
    “…Her rheumatoid arthritis was quiescent on methotrexate and etanercept. Past medical history consisted of asthma, hiatus hernia, subtalar arthrodesis and granuloma annulare. …”
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    O04 Orbital lymphoma in a 72-year-old lady with rheumatoid arthritis: an argument for rituximab
  16. 105836
    “…Abbreviations: ACAT: acetyl-CoA acetyltransferase; ACAC/ACC: acetyl-CoA carboxylase; AKT: AKT serine/threonine kinase; ATG: autophagy related; AUP1: AUP1 lipid droplet regulating VLDL assembly factor; BECN1/Vps30/Atg6: beclin 1; BSCL2/seipin: BSCL2 lipid droplet biogenesis associated, seipin; CMA: chaperone-mediated autophagy; CREB1/CREB: cAMP responsive element binding protein 1; CXCR3: C-X-C motif chemokine receptor 3; DAGs: diacylglycerols; DAMPs: danger/damage-associated molecular patterns; DEN: diethylnitrosamine; DGAT: diacylglycerol O-acyltransferase; DNL: de novo lipogenesis; EHBP1/NACSIN (EH domain binding protein 1); EHD2/PAST2: EH domain containing 2; CoA: coenzyme A; CCL/chemokines: chemokine ligands; CCl(4:) carbon tetrachloride; ER: endoplasmic reticulum; ESCRT: endosomal sorting complexes required for transport; FA: fatty acid; FFAs: free fatty acids; FFC: high saturated fats, fructose and cholesterol; FGF21: fibroblast growth factor 21; FITM/FIT: fat storage inducing transmembrane protein; FLD: fatty liver diseases; FOXO: forkhead box O; GABARAP: GABA type A receptor-associated protein; GPAT: glycerol-3-phosphate acyltransferase; HCC: hepatocellular carcinoma; HDAC6: histone deacetylase 6; HECT: homologous to E6-AP C-terminus; HFCD: high fat, choline deficient; HFD: high-fat diet; HSCs: hepatic stellate cells; HSPA8/HSC70: heat shock protein family A (Hsp70) member 8; ITCH/AIP4: itchy E3 ubiquitin protein ligase; KCs: Kupffer cells; LAMP2A: lysosomal associated membrane protein 2A; LDs: lipid droplets; LDL: low density lipoprotein; LEP/OB: leptin; LEPR/OBR: leptin receptor; LIPA/LAL: lipase A, lysosomal acid type; LIPE/HSL: lipase E, hormone sensitive type; LIR: LC3-interacting region; LPS: lipopolysaccharide; LSECs: liver sinusoidal endothelial cells; MAGs: monoacylglycerols; MAPK: mitogen-activated protein kinase; MAP3K5/ASK1: mitogen-activated protein kinase kinase kinase 5; MAP1LC3/LC3: microtubule associated protein 1 light chain 3; MCD: methionine-choline deficient; MGLL/MGL: monoglyceride lipase; MLXIPL/ChREBP: MLX interacting protein like; MTORC1: mechanistic target of rapamycin kinase complex 1; NAFLD: nonalcoholic fatty liver disease; NAS: NAFLD activity score; NASH: nonalcoholic steatohepatitis; NPC: NPC intracellular cholesterol transporter; NR1H3/LXRα: nuclear receptor subfamily 1 group H member 3; NR1H4/FXR: nuclear receptor subfamily 1 group H member 4; PDGF: platelet derived growth factor; PIK3C3/VPS34: phosphatidylinositol 3-kinase catalytic subunit type 3; PLIN: perilipin; PNPLA: patatin like phospholipase domain containing; PNPLA2/ATGL: patatin like phospholipase domain containing 2; PNPLA3/adiponutrin: patatin like phospholipase domain containing 3; PPAR: peroxisome proliferator activated receptor; PPARA/PPARα: peroxisome proliferator activated receptor alpha; PPARD/PPARδ: peroxisome proliferator activated receptor delta; PPARG/PPARγ: peroxisome proliferator activated receptor gamma; PPARGC1A/PGC1α: PPARG coactivator 1 alpha; PRKAA/AMPK: protein kinase AMP-activated catalytic subunit; PtdIns3K: class III phosphatidylinositol 3-kinase; PtdIns3P: phosphatidylinositol-3-phosphate; PTEN: phosphatase and tensin homolog; ROS: reactive oxygen species; SE: sterol esters; SIRT1: sirtuin 1; SPART/SPG20: spartin; SQSTM1/p62: sequestosome 1; SREBF1/SREBP1c: sterol regulatory element binding transcription factor 1; TAGs: triacylglycerols; TFE3: transcription factor binding to IGHM enhancer 3; TFEB: transcription factor EB; TGFB1/TGFβ: transforming growth factor beta 1; Ub: ubiquitin; UBE2G2/UBC7: ubiquitin conjugating enzyme E2 G2; ULK1/Atg1: unc-51 like autophagy activating kinase 1; USF1: upstream transcription factor 1; VLDL: very-low density lipoprotein; VPS: vacuolar protein sorting; WIPI: WD-repeat domain, phosphoinositide interacting; WDR: WD repeat domain…”
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    The ménage à trois of autophagy, lipid droplets and liver disease
  17. 105837
    por Bethlehem, R. A. I., Seidlitz, J., White, S. R., Vogel, J. W., Anderson, K. M., Adamson, C., Adler, S., Alexopoulos, G. S., Anagnostou, E., Areces-Gonzalez, A., Astle, D. E., Auyeung, B., Ayub, M., Bae, J., Ball, G., Baron-Cohen, S., Beare, R., Bedford, S. A., Benegal, V., Beyer, F., Blangero, J., Blesa Cábez, M., Boardman, J. P., Borzage, M., Bosch-Bayard, J. F., Bourke, N., Calhoun, V. D., Chakravarty, M. M., Chen, C., Chertavian, C., Chetelat, G., Chong, Y. S., Cole, J. H., Corvin, A., Costantino, M., Courchesne, E., Crivello, F., Cropley, V. L., Crosbie, J., Crossley, N., Delarue, M., Delorme, R., Desrivieres, S., Devenyi, G. A., Di Biase, M. A., Dolan, R., Donald, K. A., Donohoe, G., Dunlop, K., Edwards, A. D., Elison, J. T., Ellis, C. T., Elman, J. A., Eyler, L., Fair, D. A., Feczko, E., Fletcher, P. C., Fonagy, P., Franz, C. E., Galan-Garcia, L., Gholipour, A., Giedd, J., Gilmore, J. H., Glahn, D. C., Goodyer, I. M., Grant, P. E., Groenewold, N. A., Gunning, F. M., Gur, R. E., Gur, R. C., Hammill, C. F., Hansson, O., Hedden, T., Heinz, A., Henson, R. N., Heuer, K., Hoare, J., Holla, B., Holmes, A. J., Holt, R., Huang, H., Im, K., Ipser, J., Jack, C. R., Jackowski, A. P., Jia, T., Johnson, K. A., Jones, P. B., Jones, D. T., Kahn, R. S., Karlsson, H., Karlsson, L., Kawashima, R., Kelley, E. A., Kern, S., Kim, K. W., Kitzbichler, M. G., Kremen, W. S., Lalonde, F., Landeau, B., Lee, S., Lerch, J., Lewis, J. D., Li, J., Liao, W., Liston, C., Lombardo, M. V., Lv, J., Lynch, C., Mallard, T. T., Marcelis, M., Markello, R. D., Mathias, S. R., Mazoyer, B., McGuire, P., Meaney, M. J., Mechelli, A., Medic, N., Misic, B., Morgan, S. E., Mothersill, D., Nigg, J., Ong, M. Q. W., Ortinau, C., Ossenkoppele, R., Ouyang, M., Palaniyappan, L., Paly, L., Pan, P. M., Pantelis, C., Park, M. M., Paus, T., Pausova, Z., Paz-Linares, D., Pichet Binette, A., Pierce, K., Qian, X., Qiu, J., Qiu, A., Raznahan, A., Rittman, T., Rodrigue, A., Rollins, C. K., Romero-Garcia, R., Ronan, L., Rosenberg, M. D., Rowitch, D. H., Salum, G. A., Satterthwaite, T. D., Schaare, H. L., Schachar, R. J., Schultz, A. P., Schumann, G., Schöll, M., Sharp, D., Shinohara, R. T., Skoog, I., Smyser, C. D., Sperling, R. A., Stein, D. J., Stolicyn, A., Suckling, J., Sullivan, G., Taki, Y., Thyreau, B., Toro, R., Traut, N., Tsvetanov, K. A., Turk-Browne, N. B., Tuulari, J. J., Tzourio, C., Vachon-Presseau, É., Valdes-Sosa, M. J., Valdes-Sosa, P. A., Valk, S. L., van Amelsvoort, T., Vandekar, S. N., Vasung, L., Victoria, L. W., Villeneuve, S., Villringer, A., Vértes, P. E., Wagstyl, K., Wang, Y. S., Warfield, S. K., Warrier, V., Westman, E., Westwater, M. L., Whalley, H. C., Witte, A. V., Yang, N., Yeo, B., Yun, H., Zalesky, A., Zar, H. J., Zettergren, A., Zhou, J. H., Ziauddeen, H., Zugman, A., Zuo, X. N., Bullmore, E. T., Alexander-Bloch, A. F.
    Publicado 2022
    “…Over the past few decades, neuroimaging has become a ubiquitous tool in basic research and clinical studies of the human brain. …”
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    Brain charts for the human lifespan
  18. 105838
    “…We collected data on current and past pregnancy complications, their medical history and whether they or anyone in their household had symptoms or been diagnosed with SARS-CoV-2 infection during each trimester of their pregnancy. …”
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    SARS-CoV-2 infection in the first trimester and the risk of early miscarriage: a UK population-based prospective cohort study of 3041 pregnancies conceived during the pandemic
  19. 105839
    “…C.B.L. reports speakers’ fee from Ferring in the past, and his department receives research grants from Ferring, Merck and Guerbet. …”
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    Can hysterosalpingo-foam sonography replace hysterosalpingography as first-choice tubal patency test? A randomized non-inferiority trial
  20. 105840
    por Haagsma, Juanita A., Charalampous, Periklis, Ariani, Filippo, Gallay, Anne, Moesgaard Iburg, Kim, Nena, Evangelia, Ngwa, Che Henry, Rommel, Alexander, Zelviene, Ausra, Abegaz, Kedir Hussein, Al Hamad, Hanadi, Albano, Luciana, Liliana Andrei, Catalina, Andrei, Tudorel, Antonazzo, Ippazio Cosimo, Aremu, Olatunde, Arumugam, Ashokan, Atreya, Alok, Aujayeb, Avinash, Ayuso-Mateos, Jose Luis, Engelbert Bain, Luchuo, Banach, Maciej, Winfried Bärnighausen, Till, Barone-Adesi, Francesco, Beghi, Massimiliano, Bennett, Derrick A., Bhagavathula, Akshaya S., Carvalho, Félix, Castelpietra, Giulio, Caterina, Ledda, Chandan, Joht Singh, Couto, Rosa A. S., Cruz-Martins, Natália, Damiani, Giovanni, Dastiridou, Anna, Demetriades, Andreas K., Dias-da-Silva, Diana, Francis Fagbamigbe, Adeniyi, Fereshtehnejad, Seyed-Mohammad, Fernandes, Eduarda, Ferrara, Pietro, Fischer, Florian, Fra.Paleo, Urbano, Ghirini, Silvia, Glasbey, James C., Glavan, Ionela-Roxana, Gomes, Nelson G. M., Grivna, Michal, Harlianto, Netanja I., Haro, Josep Maria, Hasan, M. Tasdik, Hostiuc, Sorin, Iavicoli, Ivo, Ilic, Milena D., Ilic, Irena M., Jakovljevic, Mihajlo, Jonas, Jost B., Jerzy Jozwiak, Jacek, Jürisson, Mikk, Kauppila, Joonas H., Kayode, Gbenga A., Khan, Moien A. B., Kisa, Adnan, Kisa, Sezer, Koyanagi, Ai, Kumar, Manasi, Kurmi, Om P., La-Vecchia, Carlo, Lamnisos, Demetris, Lasrado, Savita, Lauriola, Paolo, Linn, Shai, Loureiro, Joana A., Lunevicius, Raimundas, Madureira-Carvalho, Aurea, Mechili, Enkeleint A., Majeed, Azeem, Menezes, Ritesh G., Mentis, Alexios-Fotios A., Meretoja, Atte, Mestrovic, Tomislav, Miazgowski, Tomasz, Miazgowski, Bartosz, Mirica, Andreea, Molokhia, Mariam, Mohammed, Shafiu, Monasta, Lorenzo, Mulita, Francesk, David Naimzada, Mukhammad, Negoi, Ionut, Neupane, Subas, Oancea, Bogdan, Orru, Hans, Otoiu, Adrian, Otstavnov, Nikita, Otstavnov, Stanislav S., Padron-Monedero, Alicia, Panda-Jonas, Songhomitra, Pardhan, Shahina, Patel, Jay, Pedersini, Paolo, Pinheiro, Marina, Rakovac, Ivo, Rao, Chythra R., Rawaf, Salman, Rawaf, David Laith, Rodrigues, Violet, Ronfani, Luca, Sagoe, Dominic, Sanmarchi, Francesco, Santric-Milicevic, Milena M., Sathian, Brijesh, Sheikh, Aziz, Shiri, Rahman, Shivalli, Siddharudha, Dora Sigfusdottir, Inga, Sigurvinsdottir, Rannveig, Yurievich Skryabin, Valentin, Aleksandrovna Skryabina, Anna, Smarandache, Catalin-Gabriel, Socea, Bogdan, Sousa, Raúl A. R. C., Steiropoulos, Paschalis, Tabarés-Seisdedos, Rafael, Roberto Tovani-Palone, Marcos, Tozija, Fimka, Van de Velde, Sarah, Juhani Vasankari, Tommi, Veroux, Massimiliano, Violante, Francesco S., Vlassov, Vasiliy, Wang, Yanzhong, Yadollahpour, Ali, Yaya, Sanni, Sergeevich Zastrozhin, Mikhail, Zastrozhina, Anasthasia, Polinder, Suzanne, Majdan, Marek
    Publicado 2022
    “…CONCLUSIONS: Injury mortality and DALY rates were highest in Eastern Europe and lowest in Western Europe, although differences in injury DALY rates declined rapidly, particularly in the past decade. The injury DALY rate ratio of highest- and lowest-ranking country declined from 2005 onwards, indicating declining inequalities in injuries between European countries.…”
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    The burden of injury in Central, Eastern, and Western European sub-region: a systematic analysis from the Global Burden of Disease 2019 Study
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