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105861por Teede, Helena J, Tay, Chau Thien, Laven, Joop, Dokras, Anuja, Moran, Lisa J, Piltonen, Terhi T, Costello, Michael F, Boivin, Jacky, Redman, Leanne M, Boyle, Jacqueline A, Norman, Robert J, Mousa, Aya, Joham, Anju E“…MAIN RESULTS AND THE ROLE OF CHANCE: The evidence in the assessment and management of PCOS has generally improved in the past five years, but remains of low to moderate quality. …”
Publicado 2023
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105862por Teede, Helena J, Tay, Chau Thien, Laven, Joop J E, Dokras, Anuja, Moran, Lisa J, Piltonen, Terhi T, Costello, Michael F, Boivin, Jacky, Redman, Leanne M, Boyle, Jacqueline A, Norman, Robert J, Mousa, Aya, Joham, Anju E“…MAIN RESULTS AND THE ROLE OF CHANCE: The evidence in the assessment and management of PCOS has generally improved in the past five years, but remains of low to moderate quality. …”
Publicado 2023
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105863“…INTRODUCTION: Despite much work over past decades, whether antigen-specific immune reactions occur in rheumatoid arthritis (RA) and to what extent such reactions are directed towards joint-specific autoantigens is still questionable. …”
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105864por Goldenberg, Larry“…The controversies surrounding testosterone replacement therapy (TRT) have been addressed in the past few years. Although the androgenic effects of TRT on normal and malignant prostate cells have been studied for over 70 years, little clinical prospective research exists on the physiological responses of prostate tissues to a wide range of serum testosterone levels. …”
Publicado 2014
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105865por Gilbody, Simon, Peckham, Emily, Bailey, Della, Arundel, Catherine, Heron, Paul, Crosland, Suzanne, Fairhurst, Caroline, Hewitt, Catherine, Li, Jinshuo, Parrott, Steve, Bradshaw, Tim, Horspool, Michelle, Hughes, Elizabeth, Hughes, Tom, Ker, Suzy, Leahy, Moira, McCloud, Tayla, Osborn, David, Reilly, Joe, Steare, Thomas, Ballantyne, Emma, Bidwell, Polly, Bonner, Sue, Brennan, Diane, Callen, Tracy, Carey, Alex, Colbeck, Charlotte, Coton, Debbie, Donaldson, Emma, Evans, Kimberley, Herlihy, Hannah, Khan, Wajid, Nyathi, Lizwi, Nyamadzawo, Elizabeth, Oldknow, Helen, Phiri, Peter, Rathod, Shanaya, Rea, Jamie, Romain-Hooper, Crystal-Bella, Smith, Kaye, Stribling, Alison, Vickers, Carinna“…The primary endpoint was smoking cessation at 12 months ascertained via carbon monoxide measurements below 10 parts per million and self-reported cessation for the past 7 days. Secondary endpoints were biologically verified smoking cessation at 6 months; number of cigarettes smoked per day, Fagerström Test for Nicotine Dependence (FTND) and Motivation to Quit (MTQ) questionnaire; general and mental health functioning determined via the Patient Health Questionnaire-9 (PHQ-9), the Generalised Anxiety Disorder-7 (GAD-7) questionnaire, and 12-Item Short Form Health Survey (SF-12); and body-mass index (BMI). …”
Publicado 2019
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105866“…He commenced 60mg prednisolone with good response and weaned according to BSR guidance. Past medical history included Barrett’s oesophagus. …”
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105867por Chen, Jacqueline, Park, Kaitlyn, Uhm, Sun Young, Spinrad, Amelia, Uniya, Apurva, Pire-Smerkanich, Nancy, Pacifici, Eunjoo“…Likewise, older adults and geriatrics have been excluded in CTs arbitrarily or to avoid adverse events associated with drug-drug interactions and comorbidities. Over the past few decades, the FDA has worked to address this issue and increase diversity and transparency in CTs. …”
Publicado 2019
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105868por Olson, John M., Evans, Cory J., Ngo, Kathy T., Kim, Hee Jong, Nguyen, Joseph Duy, Gurley, Kayla G. H., Ta, Truc, Patel, Vijay, Han, Lisa, Truong-N, Khoa T., Liang, Letty, Chu, Maggie K., Lam, Hiu, Ahn, Hannah G., Banerjee, Abhik Kumar, Choi, In Young, Kelley, Ross G., Moridzadeh, Naseem, Khan, Awais M., Khan, Omair, Lee, Szuyao, Johnson, Elizabeth B., Tigranyan, Annie, Wang, Jay, Gandhi, Anand D., Padhiar, Manish M., Calvopina, Joseph Hargan, Sumra, Kirandeep, Ou, Kristy, Wu, Jessie C., Dickan, Joseph N., Ahmadi, Sabrena M., Allen, Donald N., Mai, Van Thanh, Ansari, Saif, Yeh, George, Yoon, Earl, Gon, Kimberly, Yu, John Y., He, Johnny, Zaretsky, Jesse M., Lee, Noemi E., Kuoy, Edward, Patananan, Alexander N., Sitz, Daniel, Tran, PhuongThao, Do, Minh-Tu, Akhave, Samira J., Alvarez, Silverio D., Asem, Bobby, Asem, Neda, Azarian, Nicole A., Babaesfahani, Arezou, Bahrami, Ahmad, Bhamra, Manjeet, Bhargava, Ragini, Bhatia, Rakesh, Bhatia, Subir, Bumacod, Nicholas, Caine, Jonathan J., Caldwell, Thomas A., Calica, Nicole A., Calonico, Elise M., Chan, Carman, Chan, Helen H.-L., Chang, Albert, Chang, Chiaen, Chang, Daniel, Chang, Jennifer S., Charania, Nauman, Chen, Jasmine Y., Chen, Kevin, Chen, Lu, Chen, Yuyu, Cheung, Derek J., Cheung, Jesse J., Chew, Jessica J., Chew, Nicole B., Chien, Cheng-An Tony, Chin, Alana M., Chin, Chee Jia, Cho, Youngho, Chou, Man Ting, Chow, Ke-Huan K., Chu, Carolyn, Chu, Derrick M., Chu, Virginia, Chuang, Katherine, Chugh, Arunit Singh, Cubberly, Mark R., Daniel, Michael Guillermo, Datta, Sangita, Dhaliwal, Raj, Dinh, Jenny, Dixit, Dhaval, Dowling, Emmylou, Feng, Melinda, From, Christopher M., Furukawa, Daisuke, Gaddipati, Himaja, Gevorgyan, Lilit, Ghaznavi, Zunera, Ghosh, Tulika, Gill, Jaskaran, Groves, David J., Gurara, Kalkidan K., Haghighi, Ali R., Havard, Alexandra L., Heyrani, Nasser, Hioe, Tanya, Hong, Kirim, Houman, Justin J., Howland, Molly, Hsia, Elaine L., Hsueh, Justin, Hu, Stacy, Huang, Andrew J., Huynh, Jasmine C., Huynh, Jenny, Iwuchukwu, Chris, Jang, Michael J., Jiang, An An, Kahlon, Simran, Kao, Pei-Yun, Kaur, Manpreet, Keehn, Matthew G., Kim, Elizabeth J., Kim, Hannah, Kim, Michelle J., Kim, Shawn J., Kitich, Aleksandar, Kornberg, Ross A., Kouzelos, Nicholas G., Kuon, Jane, Lau, Bryan, Lau, Roger K., Law, Rona, Le, Huy D., Le, Rachael, Lee, Carrou, Lee, Christina, Lee, Grace E., Lee, Kenny, Lee, Michelle J., Lee, Regina V., Lee, Sean H. K., Lee, Sung Kyu, Lee, Sung-Ling D., Lee, Yong Jun, Leong, Megan J., Li, David M., Li, Hao, Liang, Xingfu, Lin, Eric, Lin, Michelle M., Lin, Peter, Lin, Tiffany, Lu, Stacey, Luong, Serena S., Ma, Jessica S., Ma, Li, Maghen, Justin N., Mallam, Sravya, Mann, Shivtaj, Melehani, Jason H., Miller, Ryan C., Mittal, Nitish, Moazez, Carmel M., Moon, Susie, Moridzadeh, Rameen, Ngo, Kaley, Nguyen, Hanh H., Nguyen, Kambria, Nguyen, Thien H., Nieh, Angela W., Niu, Isabella, Oh, Seo-Kyung, Ong, Jessica R., Oyama, Randi K., Park, Joseph, Park, Yaelim A., Passmore, Kimberly A., Patel, Ami, Patel, Amy A., Patel, Dhruv, Patel, Tirth, Peterson, Katherine E., Pham, An Huynh, Pham, Steven V., Phuphanich, Melissa E., Poria, Neil D., Pourzia, Alexandra, Ragland, Victoria, Ranat, Riki D., Rice, Cameron M., Roh, David, Rojhani, Solomon, Sadri, Lili, Saguros, Agafe, Saifee, Zainab, Sandhu, Manjot, Scruggs, Brooke, Scully, Lisa M., Shih, Vanessa, Shin, Brian A., Sholklapper, Tamir, Singh, Harnek, Singh, Sumedha, Snyder, Sondra L., Sobotka, Katelyn F., Song, Sae Ho, Sukumar, Siddharth, Sullivan, Halley C., Sy, Mark, Tan, Hande, Taylor, Sara K., Thaker, Shivani K., Thakore, Tulsi, Tong, Gregory E., Tran, Jacinda N., Tran, Jonathan, Tran, Tuan D., Tran, Vivi, Trang, Cindy L., Trinh, Hung G., Trinh, Peter, Tseng, Han-Ching H., Uotani, Ted T., Uraizee, Akram V., Vu, Kent K. T., Vu, Kevin K. T., Wadhwani, Komal, Walia, Paluk K., Wang, Rebecca S., Wang, Shuo, Wang, Stephanie J., Wiredja, Danica D., Wong, Andrew L., Wu, Daniel, Xue, Xi, Yanez, Griselda, Yang, Yung-Hsuan, Ye, Zhong, Yee, Victor W., Yeh, Cynthia, Zhao, Yue, Zheng, Xin, Ziegenbalg, Anke, Alkali, Jon, Azizkhanian, Ida, Bhakta, Akash, Berry, Luke, Castillo, Ryen, Darwish, Sonja, Dickinson, Holly, Dutta, Ritika, Ghosh, Rahul Kumar, Guerin, Riley, Hofman, Jonathan, Iwamoto, Garrick, Kang, Sarah, Kim, Andrew, Kim, Brian, Kim, Hanwool, Kim, Kristine, Kim, Suji, Ko, Julie, Koenig, Michael, LaRiviere, Alejandro, Lee, Clifton, Lee, Jiwon, Lung, Brandon, Mittelman, Max, Murata, Mark, Park, Yujin, Rothberg, Daniel, Sprung-Keyser, Ben, Thaker, Kunal, Yip, Vivian, Picard, Paul, Diep, Francie, Villarasa, Nikki, Hartenstein, Volker, Shapiro, Casey, Levis-Fitzgerald, Marc, Jaworski, Leslie, Loppato, David, Clark, Ira E., Banerjee, Utpal“…The GAL4 Technique for Real-time and Clonal Expression (G-TRACE) system allows for rapid, fluorescent protein-based visualization of both current and past GAL4 expression patterns and is therefore amenable to genome-wide expression-based lineage screens. …”
Publicado 2019
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105869por McManus, I. C., Harborne, Andrew Christopher, Horsfall, Hugo Layard, Joseph, Tobin, Smith, Daniel T., Marshall-Andon, Tess, Samuels, Ryan, Kearsley, Joshua William, Abbas, Nadine, Baig, Hassan, Beecham, Joseph, Benons, Natasha, Caird, Charlie, Clark, Ryan, Cope, Thomas, Coultas, James, Debenham, Luke, Douglas, Sarah, Eldridge, Jack, Hughes-Gooding, Thomas, Jakubowska, Agnieszka, Jones, Oliver, Lancaster, Eve, MacMillan, Calum, McAllister, Ross, Merzougui, Wassim, Phillips, Ben, Phillips, Simon, Risk, Omar, Sage, Adam, Sooltangos, Aisha, Spencer, Robert, Tajbakhsh, Roxanne, Adesalu, Oluseyi, Aganin, Ivan, Ahmed, Ammar, Aiken, Katherine, Akeredolu, Alimatu-Sadia, Alam, Ibrahim, Ali, Aamna, Anderson, Richard, Ang, Jia Jun, Anis, Fady Sameh, Aojula, Sonam, Arthur, Catherine, Ashby, Alena, Ashraf, Ahmed, Aspinall, Emma, Awad, Mark, Yahaya, Abdul-Muiz Azri, Badhrinarayanan, Shreya, Bandyopadhyay, Soham, Barnes, Sam, Bassey-Duke, Daisy, Boreham, Charlotte, Braine, Rebecca, Brandreth, Joseph, Carrington, Zoe, Cashin, Zoe, Chatterjee, Shaunak, Chawla, Mehar, Chean, Chung Shen, Clements, Chris, Clough, Richard, Coulthurst, Jessica, Curry, Liam, Daniels, Vinnie Christine, Davies, Simon, Davis, Rebecca, De Waal, Hanelie, Desai, Nasreen, Douglas, Hannah, Druce, James, Ejamike, Lady-Namera, Esere, Meron, Eyre, Alex, Fazmin, Ibrahim Talal, Fitzgerald-Smith, Sophia, Ford, Verity, Freeston, Sarah, Garnett, Katherine, General, Whitney, Gilbert, Helen, Gowie, Zein, Grafton-Clarke, Ciaran, Gudka, Keshni, Gumber, Leher, Gupta, Rishi, Harlow, Chris, Harrington, Amy, Heaney, Adele, Ho, Wing Hang Serene, Holloway, Lucy, Hood, Christina, Houghton, Eleanor, Houshangi, Saba, Howard, Emma, Human, Benjamin, Hunter, Harriet, Hussain, Ifrah, Hussain, Sami, Jackson-Taylor, Richard Thomas, Jacob-Ramsdale, Bronwen, Janjuha, Ryan, Jawad, Saleh, Jelani, Muzzamil, Johnston, David, Jones, Mike, Kalidindi, Sadhana, Kalsi, Savraj, Kalyanasundaram, Asanish, Kane, Anna, Kaur, Sahaj, Al-Othman, Othman Khaled, Khan, Qaisar, Khullar, Sajan, Kirkland, Priscilla, Lawrence-Smith, Hannah, Leeson, Charlotte, Lenaerts, Julius Elisabeth Richard, Long, Kerry, Lubbock, Simon, Burrell, Jamie Mac Donald, Maguire, Rachel, Mahendran, Praveen, Majeed, Saad, Malhotra, Prabhjot Singh, Mandagere, Vinay, Mantelakis, Angelos, McGovern, Sophie, Mosuro, Anjola, Moxley, Adam, Mustoe, Sophie, Myers, Sam, Nadeem, Kiran, Nasseri, Reza, Newman, Tom, Nzewi, Richard, Ogborne, Rosalie, Omatseye, Joyce, Paddock, Sophie, Parkin, James, Patel, Mohit, Pawar, Sohini, Pearce, Stuart, Penrice, Samuel, Purdy, Julian, Ramjan, Raisa, Randhawa, Ratan, Rasul, Usman, Raymond-Taggert, Elliot, Razey, Rebecca, Razzaghi, Carmel, Reel, Eimear, Revell, Elliot John, Rigbye, Joanna, Rotimi, Oloruntobi, Said, Abdelrahman, Sanders, Emma, Sangal, Pranoy, Grandal, Nora Sangvik, Shah, Aadam, Shah, Rahul Atul, Shotton, Oliver, Sims, Daniel, Smart, Katie, Smith, Martha Amy, Smith, Nick, Sopian, Aninditya Salma, South, Matthew, Speller, Jessica, Syer, Tom J., Ta, Ngan Hong, Tadross, Daniel, Thompson, Benjamin, Trevett, Jess, Tyler, Matthew, Ullah, Roshan, Utukuri, Mrudula, Vadera, Shree, Van Den Tooren, Harriet, Venturini, Sara, Vijayakumar, Aradhya, Vine, Melanie, Wellbelove, Zoe, Wittner, Liora, Yong, Geoffrey Hong Kiat, Ziyada, Farris, Devine, Oliver Patrick“…Data include institutional history (e.g. rate of production of hospital and GP specialists in the past), curricular influences (e.g. PBL schools, spend per student, staff-student ratio), selection measures (e.g. entry grades), teaching and assessment (e.g. traditional vs PBL, specialty teaching, self-regulated learning), student satisfaction, Foundation selection scores, Foundation satisfaction, postgraduate examination performance and fitness to practise (postgraduate progression, GMC sanctions). …”
Publicado 2020
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105870por Gorman, Ellen, Shankar-Hari, Manu, Hopkins, Phil, Tunnicliffe, William S., Perkins, Gavin D., Silversides, Jonathan, McGuigan, Peter, Jackson, Colette, Boyle, Roisin, McFerran, Jamie, McDowell, Cliona, Campbell, Christina, McFarland, Margaret, Smythe, Jon, Thompson, Jacqui, Williams, Barry, Curley, Gerard, Laffey, John G., Clarke, Mike, O’Kane, Cecilia, McAuley, Daniel F.“…Patients will be excluded for the following reasons: more than 72 hours from the onset of ARDS; age < 16 years; patient known to be pregnant; major trauma in previous 5 days; presence of any active malignancy (other than non-melanoma skin cancer); WHO Class III or IV pulmonary hypertension; venous thromboembolism currently receiving anti-coagulation or within the past 3 months; patient receiving extracorporeal life support; severe chronic liver disease (Child-Pugh > 12); Do Not Attempt Resuscitation order in place; treatment withdrawal imminent within 24 hours; prisoners; declined consent; non-English speaking patients or those who do not adequately understand verbal or written information unless an interpreter is available; previously enrolled in the REALIST trial. …”
Publicado 2020
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105871por Dinnes, Jacqueline, Deeks, Jonathan J, Adriano, Ada, Berhane, Sarah, Davenport, Clare, Dittrich, Sabine, Emperador, Devy, Takwoingi, Yemisi, Cunningham, Jane, Beese, Sophie, Dretzke, Janine, Ferrante di Ruffano, Lavinia, Harris, Isobel M, Price, Malcolm J, Taylor-Phillips, Sian, Hooft, Lotty, Leeflang, Mariska MG, Spijker, René, Van den Bruel, Ann“…Several diagnostic strategies are available to identify or rule out current infection, identify people in need of care escalation, or to test for past infection and immune response. Point‐of‐care antigen and molecular tests to detect current SARS‐CoV‐2 infection have the potential to allow earlier detection and isolation of confirmed cases compared to laboratory‐based diagnostic methods, with the aim of reducing household and community transmission. …”
Publicado 2020
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105872por Loke, (Justin) Ching Ting, Gaskell, Charlotte, Fox, Sonia, Fletcher, Rachel, Thomas, Catherine, Hopkins, Louise, Kumari, Anita, Boucher, Rebecca H., Nunnick, Jane, Knapper, Steve, Toth, Arpad, Byrne, Jennifer, O'Nions, Jenny, Khan, Anjum, Zhao, Rui, Pillai, Arvind, Tholouli, Eleni, Dungarwalla, Moez, Randall, Katie, Dillon, Richard, Murray, Duncan, Culligan, Dominic, McMullin, Mary Frances, Chan, Yuen Ling Tracey, Drew, Victoria, Murthy, Vidhya, Krishnamurthy, Pramila, Neelakantan, Pratap, Rider, Tom, Wandroo, Farooq A, Rafferty, Mark, Huang, Ya-Wen, Moore, Sally, Mehta, Priyanka, Partridge, David G, Craddock, Charles, Lowe, David, Stanworth, Simon J.“…Knapper: Pfizer: Consultancy, Speakers Bureau; Astellas: Ended employment in the past 24 months, Speakers Bureau; Jazz: Consultancy, Speakers Bureau; Novartis: Consultancy, Research Funding, Speakers Bureau. …”
Publicado 2021
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105873por Neparidze, Natalia, Wang, Rong, Zeidan, Amer M., Podoltsev, Nikolai, Shallis, Rory M., Ma, Xiaomei, Davidoff, Amy J., Huntington, Scott F.“…Shallis: Curis: Divested equity in a private or publicly-traded company in the past 24 months. Ma: Celgene/Bristol Myers Squibb: Consultancy, Research Funding. …”
Publicado 2021
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105874por Hood, Anna M, Hildenbrand, Aimee K, Rebitski, Joanna, Stallworth, Jasmine, Johnson, Yolanda, Gomes, Stacey, Whitacre, Catharine, Mara, Constance A, Shook, Lisa M, Quinn, Charles T., Raphael, Jean L., Yates, Amber M, Badawy, Sherif M., Thompson, Alexis A., Smith-Whitley, Kim, Hartung, Helge, King, Allison A., Creary, Susan E, Bhasin, Neha, Reader, Steven K, Meier, Emily R., Tubman, Venee N., Crosby, Lori E.“…Eligible children are 0 to 5 years, candidates for HU, and their caregiver has not decided about HU in the past 3 months. The trial is being conducted at 9 sites in the United States and uses a unidirectional crossover design. …”
Publicado 2021
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105875“…Traditional criminal justice strategies for combating this issue have evolved over time but have frequently demonstrated limited success. Within the past few decades, multiagency programs to address repeat family abuse have gained popularity. …”
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105876por Yang, Guang, Zhou, Siyuan, He, Haoqiang, Shen, Zinuo, Liu, Yongmei, Hu, Jun, Wang, Jie“…Multi-omics studies have revealed the biological characteristics of APOE transgenic mice, bronchopulmonary dysplasia, and plant tolerant to heavy metals (Singh et al., 2016; Lal et al., 2018; Mohler et al., 2020). Over the past few years, many academic achievements related to CHD-PBS syndrome have been accrued in the single-omic area. …”
Publicado 2022
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105877por Coward, S, Benchimol, E I, Bernstein, C, Avina-Zubieta, J A, Bitton, A, Hracs, L, Jones, J, Kuenzig, E, Lu, L, Murthy, S K, Nugent, Z, Otley, A R, Panaccione, R, Pena-Sanchez, J -N, Singh, H, Targownik, L E, Windsor, J W, Kaplan, G“…The advent of biologics over the past twenty years may have influenced the rates of hospitalization for IBD. …”
Publicado 2023
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105878por Coward, S, Benchimol, E I, Bernstein, C, Avina-Zubieta, J A, Bitton, A, Hracs, L, Jones, J, Kuenzig, E, Lu, L, Murthy, S K, Nugent, Z, Otley, A R, Panaccione, R, Pena-Sanchez, J -N, Singh, H, Targownik, L E, Windsor, J W, Kaplan, G“…By understanding historical epidemiological trends, we can forecast incidence and prevalence into the future to inform healthcare systems in Canada of the rising burden of IBD to society. PURPOSE: To analyze past epidemiological trends in order to forecast the overall incidence and prevalence of IBD, Crohn’s disease (CD), and ulcerative colitis (UC) and stratified by age (<18, 18-64, 65+). …”
Publicado 2023
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105879por Sharma, Meenakshi“…In this new state of matter, the constituent partons, namely quarks and gluons, are freed from nucleons in which they are normally confined by the strong force. Over the past two decades a panoply of measurements made in heavy ion collisions at the two highest energy Colliders : Relativistic Heavy Ion Collider (RHIC) and the Large Hadron Collider (LHC), combined with theoretical advances from calculations made in variety of frameworks, have led to a broad and deep knowledge of the properties of hot QCD matter. …”
Publicado 2023
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105880“…The authors of this manuscript have decided to approach "the Paulescu case" from its double aspect, scientific and sociopolitical, to analyze the circumstances surrounding the discovery of the antidiabetic hormone, and Paulescu's alleged antisemitic past in the historical context of the Romanian nation in the interwar period. …”
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