“…This multibillion-dollar market with expiring patents is the main driver for the development of biosimilar mAbs. …”
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“…BACKGROUND: From a therapeutic viewpoint, it is important to differentiate the underlying causes of embolism in patients with cryptogenic stroke, such as aortic arch atheroma, patent foramen ovale, and paroxysmal atrial fibrillation. …”
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“…Surgical closure of patent foramen ovale was not performed due to the age of our patient, surgical difficulties, and failure to obtain informed consent. …”
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“…We also highlight the impact of patents and exclusivities on review of HIV drugs under tFDA and illustrate the concepts using a new HIV drug as an example.…”
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“…Pfizer’s patent was found invalid in 2015, a ruling subject to ongoing appeals. …”
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“…Methods: At first, an exhaustive survey of literature and various patents available related to chitinases were carried out. …”
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“…In 2 other patients with patent ICT and MCA, MT was not initially performed, but was eventually performed because of REND due to thrombus migration, and both were discharged with an mRS score of 5. …”
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“…Although cats did not become patent, A. vasorum infections were clinically relevant. …”
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“…RESULTS: Our results show that introducing the product patent system in 1987 significantly increased the number of Korean patent applications. …”
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“…The aim of this study was to evaluate the relationship between aortic growth rate and false lumen flow dynamics and biomechanics in patients with chronic, patent AD. METHODS: Patients with a chronic AD with patent false lumen in the descending aorta and no genetic connective tissue disorder underwent an imaging follow-up including a contrast-enhanced 4D flow cardiovascular magnetic resonance (CMR) protocol and two consecutive computed tomography angiograms (CTA) acquired at least 1 year apart. …”
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“…It starts with the conditions that generate the need and then the concept of a new instrument and goes through the process of designing it and protecting it with a patent; it then proceeds through the development of a working prototype and a final refined product. …”
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“…A two wavelengths setup was developed to improve the detection threshold of an injected dye: the Patent Blue V dye. The method used consists in modulating each laser diode at a given frequency. …”
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“…The most important themes studied are patents, industrial designs and trade marks. The latest relevant piece of legislation concerning the subject matters was passed in March 2008. …”
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“…Spontaneous TMJ herniation into the EAC can be caused by a congenital bony defect known as patent Huschke's foramen, which is a very rare condition. …”
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“…Cardiac magnetic resonance imaging was valuable in characterizing the nature of the atrial mass and patent foramen ovale, helping guide the surgical approach.…”
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“…A 13-week-old baby was referred with dextrocardia, situs inversus, transposition of the great arteries, intact ventricular septum, patent foramen ovale, right aortic arch with severe preductal aortic coarctation and large patent ductus arteriosus. …”
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“…This has led to significant research activity both by academia and industry from the 1990s, accelerating research in many fields and leading to the filing of numerous patents. However, while ILs have received great interest in the patent literature, only a limited number of processes are known to have been commercialised. …”
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“…If the left ventricle (LV) is adequate to sustain systemic cardiac output without a patent duct, arch obstruction is relieved surgically and duct is divided. …”
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“…The main result achieved is a practical solution—the reactor’s scheme, classified due to a patent procedure in the Polish Patent Office.…”
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“…Based on different scenarios resulting from the aforementioned factors, four equilibrium states are observed in the system, namely {no government regulation, technology secrecy, substitution}, {no government regulation, technology secrecy, imitation}, {no government regulation, patent application, imitation}, and {government regulation, patent application, imitation}. …”
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