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  1. 3781
    “…To gain more insight into porous microneedle technologies, the scientific and patent literature is reviewed, and we focus on the possibilities and constraints of porous microneedle technologies for dermal drug delivery. …”
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    Microneedle-based drug and vaccine delivery via nanoporous microneedle arrays
  2. 3782
    “…Traditional Chinese medicines (TCMs) have attracted extensive interest throughout the world due to their long history of health protection and disease control, and the internalization of TCM preparations or patented drugs has been considered a wind vane in the process of TCM modernization. …”
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    Discovery and Current Status of Evaluation System of Bioavailability and Related Pharmaceutical Technologies for Traditional Chinese Medicines—Flos Lonicerae Japonicae—Fructus Forsythiae Herb Couples as an Example
  3. 3783
    “…In this article, we review current classification and discuss important clinical considerations in these patients; highlighting cardiac arrhythmias and structural abnormalities, patent foramen ovale, paradoxical sources, and potentially under-recognized, vascular, inflammatory, autoimmune, and hematologic sources in relation to clinical practice.…”
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    Embolic Strokes of Unknown Source and Cryptogenic Stroke: Implications in Clinical Practice
  4. 3784
    “…Exorbitant price increases for critical off-patent medicines have received considerable media attention in recent months, leading to an investigation by the U.S. …”
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    Upstream solutions for price-gouging on critical generic medicines
  5. 3785
    “…Clinical features observed in this case are consistent with the consensus phenotype in ring chromosome 4. Patent ductus arteriosus and bilateral talipes equinovarus observed in this baby widen the phenotypic spectrum associated with ring chromosome 4.…”
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    Ring Chromosome 4 in a Child with Multiple Congenital Abnormalities: A Case Report and Review of the Literature
  6. 3786
    por Petrini, Carlo
    Publicado 2017
    “…The clinical applications of stem cells pose a multitude of problems, including safety, efficacy, information and consent, the right to unproven treatments, the “right to try”, costs, access, sustainability, scientific scrupulousness, patents and regulatory aspects, to name but a few. …”
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    Bioethics of Clinical Applications of Stem Cells
  7. 3787
    por Lind, Cora
    Publicado 2012
    “…The initial discovery of materials displaying NTE over a large temperature range, combined with elucidation of the mechanism behind this unusual property, was followed by predictions that these materials will find use in various applications through controlled thermal expansion composites. While some patents have been filed and devices built, a number of obstacles have prevented the widespread implementation of NTE materials to date. …”
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    Two Decades of Negative Thermal Expansion Research: Where Do We Stand?
  8. 3788
    “…During attempted angioplasty a balloon was retained within the patent portion of the target vessel. Two 3.0 mm drug eluting coronary stents were deployed across the length of the balloon with excellent luminal preservation. …”
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    Stent-Apposition Salvage of an Anterior Tibial Artery After Inadvertent Angioplasty Balloon Retention During CTO Revascularization
  9. 3789
    “…Repeated imaging at 3 and 12 months revealed a patent stent with complete resolution of symptoms.…”
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    A novel hybrid left renal vein transposition and endovascular stenting technique for the treatment of posterior nutcracker syndrome
  10. 3790
    “…Although computed tomography angiography showed patent splanchnic arteries, an impressive hyperperfusion state of liver and spleen was visualized. …”
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    Severe Abdominal Complaints after Technical Successful Endovascular Treatment of Chronic Splanchnic Ischemia
  11. 3791
    por Oloyede, O., Obajimi, G.O.
    Publicado 2017
    “…She had surgical resection of the vaginal septum and a vaginal stent was left in-situ to keep the vagina patent during the healing process. The procedure was uneventful and she was able to achieve menstrual flow following surgery. …”
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    A CASE REPORT OF PREMENARCHIAL TRANSVERSE VAGINAL SEPTUM AT THE UNIVERSITY COLLEGE HOSPITAL, IBADAN
  12. 3792
    “…At 12 months postoperatively, the graft remained patent with normal results of vascular laboratory studies. …”
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    Successful use of continuous vasodilator infusion to treat critical vasospasm threatening a distal bypass
  13. 3793
    “…Computed tomography at 12 months documented patent extra-anatomic aortic arch debranching and no evidence of endoleak.…”
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    Reverse extra-anatomic aortic arch debranching procedure allowing thoracic endovascular aortic repair of a chronic ascending aortic aneurysm
  14. 3794
    por Shi, Hai Yun, Ng, Siew Chien
    Publicado 2018
    “…New biologic agents targeting various pathological pathways of CD are blooming in recent years, and the high cost of biologics and expiration of patents for several biologic agents have driven the utility of biosimilars for CD treatment. …”
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    The state of the art on treatment of Crohn’s disease
  15. 3795
    “…Pterosin sesquiterpenes are also involved in many patented biomedical protocols. In this work we introduce a new and convenient approach to the synthesis in three steps and more than 80% yield of d(4)-pterosin B (d(4)-Ptb) and d(4)-bromopterosin (d(4)-BrPt), useful as internal standards in the quantification of ptaquiloside.…”
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    A New Facile Synthesis of D(4)-Pterosin B and D(4)-Bromopterosin, Deuterated Analogues of Ptaquiloside
  16. 3796
    “…Unfortunately, the majority of the information about the complex Ziziphora species is only available in Russian and Chinese language, therefore, we decided gather all available information on Kazakhstan Ziziphora, namely its content compounds, medicinal uses and published patents, to draw the attention of scientists to this very interesting plant with high medicinal potential.…”
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    Kazakh Ziziphora Species as Sources of Bioactive Substances
  17. 3797
    “…The patient denied ischemic symptoms postoperatively, and duplex ultrasound examination at a 10-month follow-up showed patent interposition graft.…”
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    Repair of a symptomatic true radial artery aneurysm at the anatomic snuff box with interposition great saphenous vein graft
  18. 3798
    “…PubChem released new web interfaces, such as PubChem Target View page, Sources page, Bioactivity dyad pages and Patent View page. PubChem also released a major update to PubChem Widgets and introduced a new programmatic access interface, called PUG-View. …”
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    PubChem 2019 update: improved access to chemical data
  19. 3799
    “…Case Description  This history describes a 45-year-old woman with history of multiple cardiac operations at young age with an abandoned defibrillator lead via a patent atrial septal defect. Lead extraction was performed with first described use of rotational dilating sheaths to reduce emboli risk, hoping to avoid a fourth surgical procedure with high risk. …”
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    Misplaced Ventricular Lead via an Atrial Septal Defect–Percutaneous Extraction
  20. 3800
    “…At 1-year follow-up, the patient is asymptomatic with a widely patent stent. This case highlights the role of endovascular therapy for patients presenting with MTS causing pelvic congestion syndrome.…”
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    May-Thurner syndrome presenting as pelvic congestion syndrome and vulvar varicosities in a nonpregnant adolescent
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