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  1. 4561
    “…This review summarizes the patents of miRNA- and siRNA-based new drugs, and also provides a snapshot about significant biopharmaceutical companies that are investing for the therapeutic development of miRNA and siRNA molecules. …”
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    Therapeutic miRNA and siRNA: Moving from Bench to Clinic as Next Generation Medicine
  2. 4562
    “…The information in THPdb has been compiled from 985 research publications, 70 patents and other resources like DrugBank. The current version of the database holds a total of 852 entries, providing comprehensive information on 239 US-FDA approved therapeutic peptides and proteins and their 380 drug variants. …”
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    THPdb: Database of FDA-approved peptide and protein therapeutics
  3. 4563
    “…The following invention - Graphene Enhanced Secondary Ion Mass Spectrometry - (pending European patent application no. EP 16461554.4) is related to a method of analysing a solid substrate by means of Secondary Ion Mass Spectrometry (SIMS). …”
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    Graphene Enhanced Secondary Ion Mass Spectrometry (GESIMS)
  4. 4564
    “…Subsequent angiogram revealed patent grafts and significant decline in the left ventricular systolic function as compared to his own ECHO a year ago. …”
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    An Unusual Case of Recurrent Hypersensitivity Reaction Associated with Kounis-Like Acute Coronary Syndrome
  5. 4565
    “…The model is trained on 50,000 experimental reaction examples from the United States patent literature, which span 10 broad reaction types that are commonly used by medicinal chemists. …”
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    Retrosynthetic Reaction Prediction Using Neural Sequence-to-Sequence Models
  6. 4566
    “…From basic concepts to the real-life applications, the relevant characteristics of magnetic biomaterials are patented which are briefly discussed. The potential therapeutic and diagnostic ability of MHAp-nanostructured materials make them an ideal platform for future nanomedicine. …”
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    Magnetic hydroxyapatite: a promising multifunctional platform for nanomedicine application
  7. 4567
    “…In addition, in order to obtain an insight into the latest innovations in the commercial sector, a survey was conducted on granted patents relating to T. cacao biotechnology.…”
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    Cacao biotechnology: current status and future prospects
  8. 4568
    “…The pre-discharge transesophageal echocardiography and conventional angiography showed a patent SVC. The patient was discharged and remained asymptomatic over a 6-month follow-up. …”
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    Successful Treatment of a Catheter-Induced Superior Vena Cava Syndrome through Catheter-Directed Thrombolysis: A Case Report
  9. 4569
    “…Patent expirations for several biological products have prompted the development of alternative versions, termed ‘biosimilars’, which have comparable quality, safety and efficacy to a licensed biological medicine (also referred to as the ‘reference’ medicine). …”
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    Development and 10-year history of a biosimilar: the example of Binocrit(®)
  10. 4570
    “…To achieve this, different methods were applied to the joint information of two sets of markers (one complete and another excluding loci in patent linkage disequilibrium). This strategy allowed the detection and exclusion of markers that biased the estimation of the average population inbreeding coefficient (Wright’s fixation index F(IS)), which value was eventually estimated as around 1% using any of the methods we applied. …”
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    Inbreeding estimates in human populations: Applying new approaches to an admixed Brazilian isolate
  11. 4571
    por Kuusela, Pekka J.
    Publicado 2018
    “…The interventricular vessel is a slit between the fibers of the muscle feasible to be patent by relaxing and widening of the helical heart at the right atrial filling phase at the end of the diastole. …”
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    Interventricular Vessel of the Heart
  12. 4572
    “…The patient underwent repeat emergent coronary angiography, which showed patent stents and findings consistent with takotsubo cardiomyopathy.…”
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    Takotsubo Cardiomyopathy Mimicking Stent Thrombosis After Percutaneous Coronary Intervention
  13. 4573
    “…Following conservative management, EGD demonstrated scarring around the ulcerated region and a patent esophagus. CONCLUSIONS: This case report serves to remind physicians of the potential complications that may arise with the use of EVBL treatment for bleeding esophageal varices and to consider the use of a loop cutter, to grasp and remove the esophageal band to improve patient recovery.…”
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    A Rare Case of Complete Esophageal Obstruction Following Esophageal Variceal Band Ligation (EVBL) for Esophageal Varices Performed by Esophagogastroduodenoscopy (EGD)
  14. 4574
    “…A plethora of protein nanoparticles applications via different routes of administration are explored and reported by eminent researchers which are highlighted in the present review along with the patents granted for protein nanoparticles as drug delivery carriers.…”
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    Protein Based Nanostructures for Drug Delivery
  15. 4575
    “…Based on these results, a technology named Somartex(®) for “Self Operating MARine Trapping Extractor” was patented and built to transfer the concept from closed aquarium systems to open marine ecosystems.…”
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    Innovative Approach to Sustainable Marine Invertebrate Chemistry and a Scale-Up Technology for Open Marine Ecosystems
  16. 4576
    “…Our patient's hypoxemia improved with inhaled nitric oxide as an adjunct to mechanical ventilation without requiring extracorporeal membrane oxygenation, and eventually a percutaneous closure with a 30 mm CardioSeal patent foramen ovale closure device was accomplished. …”
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    Inhaled nitric oxide mitigates need for extracorporeal membrane oxygenation in a patient with refractory acute hypoxemic respiratory failure due to cardiac and pulmonary shunts
  17. 4577
    “…However, this pathway is not always patent due to the extensive stenosis or occlusion of the origin of CA. …”
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    Pancreaticoduodenal arcades as salvage route for transarterial embolization of life-threatening hepatic hemorrhage in patients with severe celiac axis stenosis: Case series
  18. 4578
    “…Research teams and companies are currently in dispute over patents for these CRISPR-Cas systems as numerous powerful applications are concurrently under development. …”
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    CRISPR-Cas systems: ushering in the new genome editing era
  19. 4579
    “…This is because a fixed reference point is unattainable due to ground vibrations during train passage. In this paper, a patented signal processing technique for evaluation of pseudo-deflection is presented to recover dynamic deflection of a railroad sleeper using a coupled measurement of acceleration and strain at the concrete sleeper. …”
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    Dynamic Deflection of a Railroad Sleeper from the Coupled Measurements of Acceleration and Strain
  20. 4580
    “…Patient 2 had VCD and a patent ductus arteriosis who necessitated surgical closure. …”
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    Co-existence of vocal cord dysfunction with pulmonary conditions other than asthma: A case series
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