“…With the expiration of patent protection for several biologics looming, the production of highly similar therapeutic agents has begun to emerge on the pharmaceutical market. …”
Enlace del recurso
Enlace del recurso
Enlace del recurso

“…ISHI is a Chinese traditional patent medicine used for its anti-inflammatory and hemostatic effects. …”
Enlace del recurso
Enlace del recurso
Enlace del recurso

“…While age‐related insulin resistance and hyperinsulinemia are usually considered to be secondary to changes in muscle, the liver also plays a key role in whole‐body insulin handling and its role in age‐related changes in insulin homeostasis is largely unknown. Here, we show that patent pores called ‘fenestrations’ are essential for insulin transfer across the liver sinusoidal endothelium and that age‐related loss of fenestrations causes an impaired insulin clearance and hyperinsulinemia, induces hepatic insulin resistance, impairs hepatic insulin signaling, and deranges glucose homeostasis. …”
Enlace del recurso
Enlace del recurso
Enlace del recurso

“…CT angiogram of the abdomen and pelvis showed complete situs inversus and an otherwise normal appearance of the bilateral kidneys with patent bilateral single renal arteries and longer renal vein in the right kidney. …”
Enlace del recurso
Enlace del recurso
Enlace del recurso

“…Danning tablet (DNT, a Chinese patent medicine preparation) has been clinically used to treat human liver and gallbladder diseases for more than 20 years in China. …”
Enlace del recurso
Enlace del recurso
Enlace del recurso

“…The number of publications doubles approximately every 5–6 years while a doubling of publication volume every 11 years is observed for the CAplus database (14 years if patents are excluded). Calculations of the structure and energy of compounds dominate the DFT literature.…”
Enlace del recurso
Enlace del recurso
Enlace del recurso

“…We believe that biosurfactants are going to have a significant role in many future applications in the oil industries and in this review therefore, we highlight recent important relevant applications, patents disclosures and potential future applications for biosurfactants in petroleum and related industries.…”
Enlace del recurso
Enlace del recurso
Enlace del recurso

“…Introduction. A patent urachus is a rare congenital or acquired pathology, which can lead to complications later in life. …”
Enlace del recurso
Enlace del recurso
Enlace del recurso

“…Occlusion of the vessel was presumably due to embolism from a patent foramen ovale. Thrombolysis was performed, with incomplete symptom remission, cognitive impairment, and persistence of speech disorders. …”
Enlace del recurso
Enlace del recurso
Enlace del recurso

“…On the contrary, traditional Chinese medicine (TCM) with long history of use involves various treatment methods, including Chinese herbal medicines (CHMs) or bioactive ingredients, Chinese patent medicines, acupuncture, Qigong, and Tai Chi Chuan. …”
Enlace del recurso
Enlace del recurso
Enlace del recurso

“…In the 6 of 20 patients, early re-thrombosis were detected. Patent AVF with primary and secondary patency rates at 6 and 12 months was 55%-40%. …”
Enlace del recurso
Enlace del recurso
Enlace del recurso

“…However, the rising prevalence of IBD worldwide and the ever-increasing burden of biologic pharmaceuticals in the health care industry is alarming for insurance companies, clinicians, and patients. The impending patent expiry and the relatively high costs of biologics, particularly anti-TNF agents, have paved the way for biosimilar development for IBD. …”
Enlace del recurso
Enlace del recurso
Enlace del recurso

“…While China is ascending at a great speed to a leading position worldwide in terms of Research and Development investment, scientific publications and patents, the innovation capabilities in the pharmaceutical sector remain weak. …”
Enlace del recurso
Enlace del recurso
Enlace del recurso

“…Transesophageal echocardiography showed a patent foramen ovale (PFO). Furthermore, the patient displayed hypotension as well as prerenal acute kidney injury with elevated levels of creatinine and reduced renal clearance, indicating a hypovolemic shock. …”
Enlace del recurso
Enlace del recurso
Enlace del recurso

“…Despite the fact that the immediate and 6 month follow up cerebral angiography confirmed a patent bypass, the patient still developed a posterior cerebral artery territory stroke. …”
Enlace del recurso
Enlace del recurso
Enlace del recurso

“…Breastfeeding rate was similar in intrathecal group in compare with other patents (P value = 0.518). While, the infants’ weight at the end of second month was lower in spinal opioid group (P value = 0.036). …”
Enlace del recurso
Enlace del recurso

“…Recent advances in secondary stroke prevention include new evidence in hypertension, nutrition, anticoagulation, antiplatelet therapy, intracranial stenosis, percutaneous closure of patent foramen ovale, and lipid-lowering therapy. …”
Enlace del recurso
Enlace del recurso
Enlace del recurso

“…Despite the publication of three patents on the topic, until now no bacteriophage-based product is commercially available. …”
Enlace del recurso
Enlace del recurso
Enlace del recurso

“…Naoxintong capsule (NXTC) was a famous patent medicine of Traditional Chinese Medicine (TCM) to treat cerebrovascular diseases in China. …”
Enlace del recurso
Enlace del recurso
Enlace del recurso

“…In order to keep this exposed venous end patent, we applied heparin-soaked gauze dressing to the wound. …”
Enlace del recurso
Enlace del recurso
Enlace del recurso