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5001“…In most cases, IAA is associated with an intracardiac malformation, such as ventricular septal defect, bicuspidaortic valve, and patent ductus arteriosus. We reported a 70-year-old man with isolated IAA diagnosed using computed tomography angiography (CTA) without previous intervention. …”
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5002por Zhang, Guijuan, Jiang, Xuefeng, Liu, Yusheng, Hao, Xiaoqian, Wang, Yurong, Yan, Xianxin, Yuan, Naijun, Ma, Yi, Ma, Min“…Ruyan Neixiao Cream (RYNXC), a patented Chinese herbal formula, was reported to have the effect of treating mammary precancerous disease. …”
Publicado 2019
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5003A Case of Hypotonia-Cystinuria Syndrome With Genito-Urinary Malformations and Extrarenal Involvementpor Taroni, Francesca, Capone, Valentina, Berrettini, Alfredo, De Marco, Erika Adalgisa, Manzoni, Gian Antonio, Montini, Giovanni“…We here describe a 2 years old child with HCS associated with other clinical features as congenital anomalies of kidney and urinary tract (primary obstructed megaureter, POM), cryptorchidism and cardiac involvement (patent foramen ovale with atrial septum aneurysm). …”
Publicado 2019
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5004por Kiakojuri, Keyvan, Armaki, Mojtaba Taghizadeh, Rajabnia, Ramazan, Pournajaf, Abazar, Karami, Mohsen, Khademian, Aynaz, Omran, Saeid Mahdavi“…And Aspergillus niger were the most common bacteria and fungi isolates respectively in Iranian patents. CONCLUSION: Fungal and bacterial specific cultures may be recommended, and anti-fungal drugs may be added, to treatment regimens in patients with otitis externa to reduce the clinical symptoms.…”
Publicado 2019
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5005“…Moreover, the current status of clinical trials applying ASCs and the patent landscape in the field of ASC research are presented. …”
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5006“…She remained normotensive with a patent aortic arch on echocardiography performed 10 months after treatment. …”
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5007“…Screening a custom library of 100 off-patent drugs for synergistic activity with pitavastatin identified prednisolone as the most prominent hit. …”
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5008por Yang, Seung-Ook, Nielsen, Gregory H., Wilding, Kristen M., Cooper, Merideth A., Wood, David W., Bundy, Bradley C.“…Tissue plasminogen activator (tPa) is the only FDA-approved drug to treat ischemic stroke with a wholesale price over $6000. tPa is now off patent although no biosimilar has been developed. …”
Publicado 2019
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5009por Eniu, Alexandru, Cherny, Nathan I, Bertram, Melanie, Thongprasert, Sumitra, Douillard, Jean-Yves, Bricalli, Gracemarie, Vyas, Malvika, Trapani, Dario“…In low- and middle-income countries, some barriers to the accessibility of anticancer medicines include the lack of government reimbursement, budget allocation for healthcare and quality-assured generic and biosimilar medicines, as well as shortages and patent rights. Throughout the article, the session presenters provide their views on strategies that can be considered to overcome these barriers.…”
Publicado 2019
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5010por Ye, Lianbao, Zhao, Tao, Du, Wenjun, Li, Anhu, Gao, Wei, Li, Jingrong, Wang, Ling, Chen, Weiqiang“…In this study, we designed aminopyridine-containing spiro [indoline-3,4′-piperidine] derivatives A1-A4 using Neratinib and spiro [indoline-3, 4′-piperidine]-2-one compound patented as lead structure, then replaced piperidine with cyclopropane to obtain B1-B7 and replaced indoline with benzmorpholine to get C1-C4 and D1-D2. …”
Publicado 2019
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5011por Kafle, Paritosh, Shrestha, Binav, Mandal, Amrendra, Sharma, Dikshya, Bhandari, Manjul, Amgai, Birendra, Khalid, Mazin, Sidhu, Jasdeep S, Solaimanzadeh, Isaac, Gayam, Vijay, Surana, Rahul, Dufresne, Alix“…Upon admission, cardiac catheterization revealed patent coronary arteries. Stark regional wall motion abnormalities were observed along with reduced ejection fraction. …”
Publicado 2019
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5012“…Transthoracic echocardiography revealed a small patent foramen ovale (PFO) and a circumferential mobile cystic mass in the right atrium, with the impression of a tumour or thrombus. …”
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5013por Moonens, Marc, Wyart, Eric, De Baere, Dieter, Hinderdael, Michaël, Ertveldt, Julien, Jardon, Zoé, Arroud, Galid, Guillaume, Patrick“…This paper addresses the influence on the fatigue life induced by the implementation of a capillary-based structural health monitoring methodology, patented under the name eSHM. It consists in integrating structurally small and pressurized capillaries into the component, so that when a fatigue crack breaches the capillary network, it results in a leak flow to the open atmosphere and loss of pressure in the galleries which is detected by a pressure sensor. …”
Publicado 2019
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5014por Corsini, Iuri, Ficial, Benjamim, Fiocchi, Stefano, Schena, Federico, Capolupo, Irma, Cerbo, Rosa Maria, Condò, Manuela, Doni, Daniela, La Placa, Simona, Porzio, Salvatore, Rossi, Katia, Salvadori, Sabrina, Savoia, Marilena“…All the respondents used NPE in neonates with patent ductus arteriosus and persistent pulmonary hypertension, 93% in neonates with hypotension or shock, 85% in neonates with perinatal asphyxia, 78% in suspicion of cardiac tamponade, and 73% for line positioning. …”
Publicado 2019
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5015“…CASE PRESENTATION: A 63-year-old man had a muscular ventricular septal defect complicated by mitral regurgitation and a 57-year-old man had patent ductus arteriosus complicated by aortic stenosis. …”
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5016por Grinnan, Daniel, Trankle, Cory, Andruska, Adam, Bloom, Bruce, Spiekerkoetter, Edda“…We furthermore discuss various data-driven as well as experimental approaches currently used to identify repurposed drug candidates and review challenges for the “repositioning community” with regards to funding and patent and regulatory considerations, and to illustrate opportunities for collaborative solutions for drug repositioning relevant to PAH.…”
Publicado 2019
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5017por Tang, Jia, Ma, Wei, Chen, Yangran, Jiang, Runze, Zeng, Qinlong, Tan, Jieliang, Jiang, Hongqing, Li, Qing, Zhang, Victor W., Wang, Jing, Tang, Hui, Luo, Liangping“…The twins showed clinical symptoms of facial weakness, hypotonia, arthrogryposis, strephenopodia, patent ductus arteriosus, and pulmonary arterial hypertension. …”
Publicado 2019
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5018“…Through a review of literature, manufacturer products, and patents, four principal cricothyrotomy devices currently in clinical use were identified. …”
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5019“…Management of persistent patent ductus arteriosus (PDA) continues to be a challenging issue. …”
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5020“…To better understand how science-based university spin-offs can be endowed for success, the pre-formation stage of 30 ventures co-founded over a 40 year period by a star-scientist-entrepreneur is analysed by matching his 363 co-invented US patents granted to 1476 co-authored publications and these 30 ventures. …”
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