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5861por Yu, Su Jong, Yoon, Jung-Hwan, Kim, Won, Lee, Jeong Min, Lee, Yun Bin, Cho, Yuri, Lee, Dong Hyeon, Lee, Minjong, Yoo, Jeong-Ju, Cho, Eun Ju, Lee, Jeong-Hoon, Kim, Yoon Jun, Kim, Chung Yong“…Imaging studies showed patent portal veins at the end of the study period. …”
Publicado 2017
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5862“…RESULTS: All anastomotic sites were patent, without stenosis, occlusion, or dilatation. …”
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5863“…Biologic therapies have revolutionized treatment of a number of diseases. Patents and exclusivity for a number of biologics are expiring. …”
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5864“…METHODS: The present report summarizes data related to SANTAVAC™ development, including technical key points associated with optimal SANTAVAC™ production, a description of the composition required for preparing cancer vaccines with the highest predicted efficacy and safety, and a strategy for SANTAVAC™ large-scale implementation. Patents related to SANTAVAC™ and other universal cancer vaccines are also described. …”
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5865“…Many biologics, including rituximab, have lost exclusivity of composition-of-matter patent or will do so in the next few years, which is a concern for patients and physicians alike. …”
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5866por Yokoyama, Utako, Tonooka, Yuta, Koretake, Ryoma, Akimoto, Taisuke, Gonda, Yuki, Saito, Junichi, Umemura, Masanari, Fujita, Takayuki, Sakuma, Shinya, Arai, Fumihito, Kaneko, Makoto, Ishikawa, Yoshihiro“…The patch medial grafts were sutured at the rat aorta and found to be completely patent and endothelialized after 2.5 months, although tubular medial constructs implanted in rats as interpositional aortic grafts withstood arterial blood pressure only in early acute phase. …”
Publicado 2017
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5867por Saenger, Paul“…With the expiration of patent exclusivity for the first wave of rhGH products and other biopharmaceuticals, the opportunity emerged for the development of biosimilar medicines. …”
Publicado 2017
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5868“…Because of the high cost of biological drugs and their patent expiration, the market has opened to biosimilar agents, copy versions of the originators, which can lead to reduced health care expenditure and increase treatment access worldwide. …”
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5869“…The graft continues to function well 36 months post-transplant, with normal liver function tests and imaging revealing a patent hepaticojejunostomy. DISCUSSION: The potential associated vascular injuries should be identified during bench preparation whilst the management of biliary reconstruction at the time of transplant should follow the principles of biliary reconstruction in cases with biliary injuries, extending the hilar opening into the left duct. …”
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5870por Qin, Gordon, Lo, Jessica W., Marlow, Neil, Calvert, Sandy A., Greenough, Anne, Peacock, Janet L.“…Logistic regression, adjusted for sex, birthweight z-score, gestation, maternal smoking, oxygen dependency at 36 weeks, airleak, patent ductus arteriosus, pulmonary haemorrhage, major ultrasound abnormality, mode of ventilation and age at assessment, was undertaken. …”
Publicado 2017
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5871por Wang, Chengen, Yang, Min, Tong, Xiaoqiang, Wang, Jian, Guan, Haitao, Niu, Guochen, Yan, Ziguang, Zhang, Bihui, Zou, Yinghua“…METHODS: This was a retrospective review of medical records and imaging findings from patients with renal AMLs who attended our clinic and received SAE between January 2007 and January 2014. Only patents with complete medical records, preoperative computed tomography scans using typical imaging and follow-up data were included. …”
Publicado 2017
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5872“…Vessels were defined as patent or occluded. RESULTS: Out of 1 406 patients, incidence of vertebral basilar artery brain infarction and posterior cerebral artery brain infarction were significantly higher in patients with diabetes versus those without diabetes (35.5% versus 22.3% and 11.7% versus 6.8%, respectively). …”
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5873“…The bypass grafts were patent at 47.1±58.9 months in 7 patients who underwent follow-up imaging studies. …”
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5874“…BOSS is a resource of experimentally validated breast oncogenic siRNAs, collected from research articles and patents published yet. The present database contains information on 865 breast oncogenic siRNA entries. …”
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5875“…Anatomical and functional success was defined by a patent syringing and the absence of epiphora respectively. …”
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5876por Li, Minghui, Jiang, Chuan, Ye, Lincai, Wang, Shoubao, Zhang, Haibo, Liu, Jinfen, Hong, Haifa“…These findings indicate that NCX1 may play a role in maintaining patent DA not only by preventing DA functional closure through reducing cytosolic Ca(2+) level in DASMC but also by delaying the anatomical closure process. …”
Publicado 2017
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5877“…According to the new policy, off-patent brand-name drugs (original drugs) and generic drugs must be priced the same. …”
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5878por Wang, LiJuan, Li, Rui, Che, KeKe, Liu, ZhongHong, Xiang, ShiFeng, Li, MengYa, Yu, Yu“…We developed a novel lung-targeted DTX-loaded liposome (DTX-LP), an efficient drug delivery system, with a patented DBaumNC technology to overcome these deficiencies. …”
Publicado 2017
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5879por Wang, Hui, Guo, Liping, Shang, Hongcai, Ren, Ming, Wang, Xuemei, Wang, Dehui, Chen, Jianzong, Li, Shuanglei, Chen, Liming, Wang, Yue, Liu, Zhi, Zhai, Jingbo, Song, Yuzhen, Cao, Hongbo, Zhang, Junhua, Liu, Chunxiang, Sun, Xiao, Huo, Da, Mu, Wei, Zhang, Li, Zheng, Wenke, Yan, Xiaoyan, Yao, Chen“…This study observed the efficacy and safety of JinqiJiangtang tablets (JQJT tablets, a traditional Chinese patent medicine) for pre-diabetes. Four hundred patients with pre-diabetes at five centres were treated for 12months and followed for an additional 12months to investigate the preventative effects of JQJT tablets (Registration ID: ChiCTR-PRC-09000401). …”
Publicado 2017
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5880“…METHODS: Out of a series of 173 patients undergoing redo cardiac valve surgery, 24 patients were reoperative via the right anterolateral thoracotomy as the high-risk group on the basis of the proximity of the heart and great vessels to the sternum and the presence and location of patent bypass grafts. RESULTS: In all cases, sternotomy was avoided. …”
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