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  1. 5901
    “…Carbamazepine, allopurinol, and penicillins were the most common single offending drugs (17.5%, 9.6%, and 7.2%). Chinese patent medicines accounted for 5.4%. There were 76 (45.8%) patients receiving systemic steroid and intravenous immunoglobulin (IVIG) in combination therapy, especially for TEN (80.3%), and others were treated with systemic steroids alone. …”
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    The Epidemiology of Stevens-Johnson Syndrome and Toxic Epidermal Necrolysis in China
  2. 5902
    “…The most associated cardiac malformations with ocular findings were interatrial communication (77.4%), interventricular communication (51.6%), patent ductus arteriosus (35.4%), pulmonary artery stenosis (25.8%) and tetralogy of Fallot (22.5%). …”
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    Genetic Syndromes Associated with Congenital Cardiac Defects and Ophthalmologic Changes - Systematization for Diagnosis in the Clinical Practice
  3. 5903
    “…Cardiac catheterization disclosed patent coronary arteries and he was discharged. A year later he returned with similar angina-like chest pain. …”
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    Adrenocorticotropic Hormone Secreting Pheochromocytoma Underlying Glucocorticoid Induced Pheochromocytoma Crisis
  4. 5904
    “…In CG, TEAs remained patent for 1 month, but became partly occluded 1 week after catheter withdrawn. …”
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    The development of an extra-anatomic tissue-engineered artery with collateral arteries for therapeutic angiogenesis in ischemic hind limb
  5. 5905
    “…Color Doppler ultrasound may be applied to evaluate and differentiate the patent, stenosis and occlusion of carotid arteries in rabbits with different vascular grafts implanted. …”
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    Accurate and continuous ultrasonography evaluation of small diameter vascular prostheses in vivo
  6. 5906
    “…Expression of ZBTB16, the lineage-determining transcription factor of type I NKT cells, was correlated with a favorable patient prognosis in the METABRIC dataset, and BTLA levels were instrumental to further distinguish prognosis in patents with high ZBTB16 expression. Taken together, these data support a role of BTLA on type I NKT cells in limiting anti-tumor immunity.…”
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    Downregulation of BTLA on NKT Cells Promotes Tumor Immune Control in a Mouse Model of Mammary Carcinoma
  7. 5907
    “…RESULTS: CHM treatment principle and formulae based on pattern differentiation together with approved patent herbal medicines are the main treatments for POAG, and the diagnosis and treatment focusing on blood related patterns is the major domain. …”
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    Evidence-based practice guideline of Chinese herbal medicine for primary open-angle glaucoma (qingfeng -neizhang)
  8. 5908
    “…A preoperative coronary angiogram demonstrated widely patent left and right coronary arteries. In June 2017, the patient presented to the hospital with chest pain. …”
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    Delayed Development of Coronary Ostial Stenosis following Surgical Aortic Valve Replacement: A Case Report of Unusual Presentation
  9. 5909
    “…METHODS: We describe a hESC line developed through a patented technology that does not lead to immune reaction upon transplantation. …”
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    Human Embryonic Stem Cell Derived from Early Stage Fertilized Ovum: Non Immunogenic and Universal, Neuronal and Non-neuronal Cell Lines
  10. 5910
    “…This study investigates biofuel production from wheat straw hydrolysate, from which furfural was extracted using a patented method developed at the Latvian State Institute of Wood Chemistry. …”
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    Bioethanol and lipid production from the enzymatic hydrolysate of wheat straw after furfural extraction
  11. 5911
    “…Climate change is not only evident, but its implications on biodiversity are already patent. The scientific community has delved into the limitations and capabilities of species to face changes in climatic conditions through experimental studies and, primarily, Species Distribution Models (SDMs). …”
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    Assessment of the effect of climate changes in the Late Pleistocene and Holocene on niche conservatism of an arvicolid specialist
  12. 5912
    “…METHODS: A state-of-the-art review of peer-reviewed publications, patents, global health databases, and online resources was performed. …”
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    Medical device landscape for communicable and noncommunicable diseases in low-income countries
  13. 5913
    “…Model-based approaches confer benefits at all stages of the drug life-cycle, from identifying the first dose to be used in children, to clinical trial design, and optimising the dosing regimens of older, off-patent medications. To benefit patients, strategies to ensure that new PK, PD and trial data are incorporated into evidence-based dosing recommendations are needed. …”
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    Pharmacokinetic studies in children: recommendations for practice and research
  14. 5914
    “…An unprecedented number of clinical studies validating this patented nutrigenomic technology in re-balancing brain chemistry and optimizing dopamine sensitivity and function have been published. …”
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    “Dopamine homeostasis” requires balanced polypharmacy: Issue with destructive, powerful dopamine agents to combat America’s drug epidemic
  15. 5915
    “…This study suggests that performing surgical procedures in a NICU with air cleanliness class 7 is as safe as in an OR, as least in part, when performing patent ductus arteriosus ligation and exploratory laparotomy.…”
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    The beneficial effect of air cleanliness with ISO 14644-1 class 7 for surgical intervention in a neonatal intensive care unit: A 10-year experience
  16. 5916
    por Alphandéry, Edouard
    Publicado 2018
    “…Finally societal and economic aspects are described with a presentation of the orphan drug status that can accelerate the development of GBM therapies, patents protecting various GBM treatments, the different actors tackling GBM disease, the cost of GBM treatments, GBM market figures, and a financial analysis of the different companies involved in the development of GBM therapies.…”
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    Glioblastoma Treatments: An Account of Recent Industrial Developments
  17. 5917
    “…In our study, Qingfei Xieding was investigated as a novel Chinese traditional patent medicine against pulmonary fibrosis. A pulmonary fibrosis mouse model was constructed by injecting with bleomycin sulfate. …”
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    A Chinese Traditional Therapy for Bleomycin-Induced Pulmonary Fibrosis in Mice
  18. 5918
    “…Pathways to accessing DAAs include developing comprehensive viral hepatitis plans to facilitate price negotiations, voluntary and compulsory licenses, patent opposition, joint procurement, and personal importation schemes. …”
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    Pathways to ensure universal and affordable access to hepatitis C treatment
  19. 5919
    “…PURPOSE: Filgrastim, a recombinant human granulocyte-colony stimulating factor, is widely used to treat congenital and acquired neutropenia. Following patent expiration of the innovator filgrastim product, biosimilar filgrastim products have been approved in the EU and shown to be comparable with the innovator with respect to quality, safety and efficacy. …”
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    Quality Comparison of Biosimilar and Copy Filgrastim Products with the Innovator Product
  20. 5920
    “…Sangju Ganmao tablet (SGT), a well-known Chinese patent medicine used to treat cold symptoms, is made from eight herbal medicines. …”
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    Chemical Profiling and Comparison of Sangju Ganmao Tablet and Its Component Herbs Using Two-Dimensional Liquid Chromatography to Explore Compatibility Mechanism of Herbs
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