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6481por Biglia, Nicoletta, Sgandurra, Paola, Bounous, Valentina Elisabetta, Maggiorotto, Furio, Piva, Eleonora, Pivetta, Emanuele, Ponzone, Riccardo, Pasini, Barbara“…OBJECTIVES: To compare clinical–pathological characteristics and outcome between sporadic ovarian cancer and ovarian cancer in patents with hereditary breast and ovarian cancer syndrome (HBOC). …”
Publicado 2016
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6482por Baikoussis, Nikolaos G., Argiriou, Orestis, Argiriou, Michalis, Psevdi, Aikaterini, Kratimenos, Theodoros, Dedeilias, Panagiotis“…At 5-year follow-up, an aneurysm of the thyreocervical trunk was found while the stent-graft of the aorta was well-tolerated without endoleak and the carotid-subclavian graft was patent. The aneurysm was asymptomatic but considering the risk of spontaneous rupture of an aneurysm of this size, elective surgery was indicated. …”
Publicado 2016
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6483“…CONTEXT: Successful arterial cannulation requires wide and patent arterial lumen. A recent study has shown that success rate of radial arterial cannulation at first attempt is more at 45° angle of wrist extension in both young and elderly patients. …”
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6484“…A 10-year-old female child was diagnosed as IE with a patent ductus arteriosis (PDA) and a vegetation on the left side of pulmonary artery trunk (10 × 5 mm(2)). …”
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6485por Tan, Hui-Li, Chan, Kok-Gan, Pusparajah, Priyia, Saokaew, Surasak, Duangjai, Acharaporn, Lee, Learn-Han, Goh, Bey-Hing“…The currently utilized applications of icariin and its derivatives in cancer treatment are explored with reference to existing patents. Based on the data compiled, icariin and its derivatives are shown to be compounds with tremendous potential for the development of new anti-cancer drugs.…”
Publicado 2016
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6486por Qu, Yanji, Liu, Xiaoqing, Zhuang, Jian, Chen, Guanchun, Mai, Jinzhuang, Guo, Xiaoling, Ou, Yanqiu, Chen, Jimei, Gong, Wei, Gao, Xiangmin, Wu, Yong, Nie, Zhiqiang“…The increase in incidence occurred mainly for single lesion and the most common subtypes (e.g., ventricular or atrial septal defect, patent ductus arteriosus). There were no increases found for multiple lesions or more complex subtypes. …”
Publicado 2016
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6487por Hinojosa, Carlos A., Lizola, Rene, Anaya-Ayala, Javier E., Torres-Machorro, Adriana, Laparra-Escareno, Hugo“…At three months she remains symptoms-free and her bypass is patent. DISCUSSION/CONCLUSION: This case illustrates the clinical presentation of TA affecting both carotid arteries; open revascularization via carotid subclavian bypass grafting was successfully performed with minimal morbidity, complete resolution of symptoms and improvement of the patient’s quality of life. …”
Publicado 2016
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6488por Kors, Jan A, Clematide, Simon, Akhondi, Saber A, van Mulligen, Erik M, Rebholz-Schuhmann, Dietrich“…Materials and methods We selected text units from different parallel corpora (Medline abstract titles, drug labels, biomedical patent claims) in English, French, German, Spanish, and Dutch. …”
Publicado 2015
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6489“…In general, access to finance and the firms’ location are significant factors that are associated with graphene product introductions. We also find that patents and scientific publications are not statistically significant predictors of product development in our sample of graphene enterprises. …”
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6490“…Brand name tacrolimus (Prograf(®)) came off patent in April 2008. However, published evidence supporting therapeutic equivalence of generic formulations of tacrolimus in solid organ transplantation is lacking. …”
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6491“…Twenty-five of them were infants and children (6 days to 11 years of age), one was a teenager (14-years of age), and another was a 33-year-old man [mean ± standard deviation (SD): 5.80 ± 3.90 years]. Thirteen patents were males (mean ± SD: 6.587077 ± 5.02 years) and 14 were females (mean ± SD: 5.0726 ± 2.81 years). …”
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6492“…RESULTS: The authors describe new trial data for heart failure (including eplerenone, finerenone, patiromer, sacubitril/valsartan, the beta 3 agonist mirabegron, sitagliptin, empagliflozin, alginate-hydrogel LV epicardial implant), anticoagulation (idarucizumab and andexanet alfa reversal agents, adherence programmes, practice in ablation), transcatheter aortic valve replacement (long-term data, valve-in-valve use, the TriGuard embolic deflecting device), patent foramen ovale closure, cardiovascular prevention (PCSK9 inhibitors, hypertension treatment) and antiplatelets strategies (extended duration therapy with clopidogrel or ticagrelor). …”
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6493por Xie, Jiajun, Juan, Yu-Hsiang, Wang, Qiushi, Chen, Jimei, Zhuang, Jian, Xie, Zhaofeng, Liang, Changhong, Zhu, Yulei, Yu, Zhuliang, Li, Jinglei, Saboo, Sachin S., Liu, Hui“…Most patients (40/47, 85%) had associated cardiovascular anomalies, of which ventricular septal defects (22/47, 47%), atrial septal defects (20/47, 43%), patent ductus arteriosus (16/47, 34%), persistent left superior vena cava (14/47, 30%), and abnormal branching of the right pulmonary artery (ABRPA) (14/47, 30%) were most commonly identified. …”
Publicado 2017
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6494por Kocic, Gordana, Veljkovic, Andrej, Kocic, Hristina, Colic, Miodrag, Mihajlovic, Dusan, Tomovic, Katarina, Stojanovic, Svetlana, Smelcerovic, Andrija“…The aim of this study was the evaluation of 15 days dietary regimen of depurinized (DP) milk (obtained using our patented technological procedures) or 1.5% fat UHT milk instead of standard chow diet, on rat thymus and bone marrow MyD88/Akt/p38, NF-κB, caspase-1 and endonuclease pathways, in relation to peripheral blood cell composition. …”
Publicado 2017
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6495por Sojka, Bartlomiej, Liskova, Aurelia, Kuricova, Miroslava, Banski, Mateusz, Misiewicz, Jan, Dusinska, Maria, Horvathova, Mira, Ilavska, Silvia, Szabova, Michaela, Rollerova, Eva, Podhorodecki, Artur, Tulinska, Jana“…The surface functionalization of <10-nm NPs was performed according to our variation of patent pending ligand exchange method that resulted in meso-2,3-dimercaptosuccinic acid (DMSA) molecules on their surface. …”
Publicado 2017
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6496por Takahashi, Kazuhiro, Prashar, Rohini, Putchakayala, Krishna G, Kane, William J, Denny, Jason E, Kim, Dean Y, Malinzak, Lauren E“…Doppler ultrasound demonstrated an extensive peri-allograft hypoechoic area and abnormal waveforms with absent arterial diastolic flow and a patent renal vein. Despite surgical decompression, the allograft failed to respond appropriately due to the delay in surgical intervention. …”
Publicado 2017
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6497por Fan, Chengming, Yang, Yifeng, Xiong, Lian, Yin, Ni, Wu, Qin, Tang, Mi, Yang, Jinfu“…Follow-up echocardiography 2–10 years after the procedure showed that the reconstructed right ventricular outflow tract (RVOT) and pulmonary artery were patent, showing no evidence of flow obstruction. Only mild regurgitation of the bovine jugular vein valve was observed. …”
Publicado 2017
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6498“…Professor Maree Smith and her group from the University of Queensland (Australia) patented the drug and many related derivatives and other compounds with high affinity for the AT2R for the indication neuropathic pain in 2004, an example of drug repositioning. …”
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6499por Simbulan-Rosenthal, Cynthia M., Dakshanamurthy, Sivanesan, Gaur, Anirudh, Chen, You-Shin, Fang, Hong-Bin, Abdussamad, Maryam, Zhou, Hengbo, Zapas, John, Calvert, Valerie, Petricoin, Emanuel F., Atkins, Michael B., Byers, Stephen W., Rosenthal, Dean S.“…These data suggest that MBZ, a well-tolerated off-patent approved drug, should be considered as a therapeutic option in combination with trametinib, for patients with NRAS(Q61mut) or other non-V600E BRAF mutant melanomas.…”
Publicado 2017
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6500“…Three mechanisms underlying the appearance of arterial bubbles should be considered: patent foramen ovale, intrapulmonary arteriovenous anastomoses, and the evolution of bubbles in the distal arteries with preference for the spinal cord. …”
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