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  1. 7761
    “…The 5 leading ACHD diagnoses were ventricular septal defect, secundum atrial septal defect, patent ductus arteriosus, pulmonary stenosis, and tetralogy of Fallot. …”
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    Adult Congenital Heart Disease in a Nationwide Population 2000–2014: Epidemiological Trends, Arrhythmia, and Standardized Mortality Ratio
  2. 7762
    “…Thirty-two of the patients who achieved full lysis and were followed up remained patent at follow-up. At 12 months seven patients had symptoms of post-thrombotic syndrome. …”
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    Results of catheter-directed thrombolysis for acute ilio-femoral deep venous thrombosis – A retrospective cohort study
  3. 7763
    “…For renal dysplasia and maternal infections, increasing trends may be explained by increased screening, and deceases in patent ductus arteriosus at term and increases in craniosynostosis, by improved follow up period after birth and improved diagnosis. …”
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    Trends in congenital anomalies in Europe from 1980 to 2012
  4. 7764
    por Shi, Rui, Zhao, Lei, Qi, Yun
    Publicado 2018
    “…CONCLUSION: Oral administration of fenofibrate was suggestively associated with thicker RNFL in superior quadrant of the right eye of patents with early DR.…”
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    The effect of fenofibrate on early retinal nerve fiber layer loss in type 2 diabetic patients: a case-control study
  5. 7765
    “…RESULTS: Sixteen patients were included (M:F 3:1). 15/16 patents (93%) had autonomic dysfunction on COMPASS 31 questionnaire. …”
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    The Spectrum of Autonomic Dysfunction in Myasthenic Crisis
  6. 7766
    “…Focusing mainly in the main regulatory and patent law issues, we will argue that (a) general moratoriums and blank prohibitions do a disservice to science and innovation; (b) it is crucial to carefully consider a complex body of international and European fundamental rights norms applicable to gene editing; (c) these require further developments grounded in consistent and coherent implementation and interpretation; (d) legal development should follow a critical contextual approach capable of integrating interdisciplinary contributions and broad multilevel societal dialog.…”
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    Cutting edges and weaving threads in the gene editing (Я)evolution: reconciling scientific progress with legal, ethical, and social concerns
  7. 7767
    “…Similar results were also obtained in patients who underwent laparoscopic TME (OR: 2.11, 95% CI: 1.15–3.89, P = 0.016). CONCLUSIONS: Male patents were found to have an increased risk for AL following TME with a primary anastomosis. …”
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    Male gender is associated with an increased risk of anastomotic leak in rectal cancer patients after total mesorectal excision
  8. 7768
    “…One reason for failure of the repair is persistent FL perfusion from distal entry tears. This creates a patent FL channel which can be associated with FL growth. …”
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    Validated Computational Model to Compute Re-apposition Pressures for Treating Type-B Aortic Dissections
  9. 7769
    “…Tongguan capsule (TGC), a patented Chinese medicine, has been shown to be cardioprotective in both humans and animals following ischemic injury, although its precise mechanism remains unclear. …”
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    Tongguan Capsule Mitigates Post-myocardial Infarction Remodeling by Promoting Autophagy and Inhibiting Apoptosis: Role of Sirt1
  10. 7770
    “…Despite the clinical benefits associated with use of biologics in psoriasis, many patients are not treated with biologic therapy, and access to treatment may be limited for various reasons, such as high treatment costs. Patents for many biologics have expired or will soon expire, and biosimilar versions of these agents are available or in development. …”
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    Biosimilar Drugs for Psoriasis: Principles, Present, and Near Future
  11. 7771
    “…The SNPscan(™) genotyping assay, a patented technology, was used to test the genotyping of miRNA-146a rs2910164 C>G polymorphism. …”
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    miRNA-146a rs2910164 C>G polymorphism increased the risk of esophagogastric junction adenocarcinoma: a case–control study involving 2,740 participants
  12. 7772
    “…RESULTS: The findings of the present study in both districts indicate that nitroxynil, oxyclozanide, closantel and triclabendazole are effective against patent F. gigantica infection, as the calculated FECR% for each trematocide was 100% by day 14 post-treatment. …”
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    Evaluating the effectiveness of trematocides against Fasciola gigantica and amphistomes infections in cattle, using faecal egg count reduction tests in Iringa Rural and Arumeru Districts, Tanzania
  13. 7773
    “…The ratings at months 12, 24, and 36 were used to allocate patents to either “persisting pain” or “non-persisting pain” groups. …”
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    Machine-learning-derived classifier predicts absence of persistent pain after breast cancer surgery with high accuracy
  14. 7774
    por Lexchin, Joel
    Publicado 2018
    “…DATA SOURCES: Therapeutic Products Directorate, Biologics and Genetic Therapies Directorate, Notice of Compliance database, Notice of Compliance with conditions web site, Patented Medicine Prices Review Board, La revue Prescrire, WHO Anatomical Therapeutic Chemical classification system. …”
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    Health Canada’s use of expedited review pathways and therapeutic innovation, 1995–2016: cross-sectional analysis
  15. 7775
    “…We excluded patients with isolated patent ductus arteriosus or pulmonary hypertension (n = 45) and compared outcomes of patients with hemodynamically relevant CHD (n = 38) and those without CHD (n = 91). …”
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    Congenital Heart Disease Increases Mortality in Neonates With Necrotizing Enterocolitis
  16. 7776
    “…However, the recent expiration of its patent has allowed the entry of the first Infliximab biosimilar into the European and Spanish markets. …”
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    Loss of efficacy and safety of the switch from infliximab original to infliximab biosimilar (CT-P13) in patients with inflammatory bowel disease
  17. 7777
    “…BACKGROUND: Misdiagnosis of autoimmune pancreatitis (AIP) as pancreatic cancer (PDAC) or vice versa can cause dismal patents’ outcomes. Changes in IgG glycosylation are associated with cancers and autoimmune diseases. …”
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    High accuracy differentiating autoimmune pancreatitis from pancreatic ductal adenocarcinoma by immunoglobulin G glycosylation
  18. 7778
    “…With prevalence of 41% among the human population and the prevalence of 18.4% patent infection among the snail intermediate hosts, urogenital schistosomiasis is still a public health problem in the study area and falls within the WHO classification of endemic area. …”
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    Transmission Dynamics of Urogenital Schistosomiasis in the Rural Community of Ebonyi State, South Eastern Nigeria
  19. 7779
    “…BACKGROUND: Creating a patent airway by cricothyrotomy is the ultimate maneuver to allow oxygenation (and ventilation) of the patient. …”
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    Prehospital cricothyrotomies in a helicopter emergency medical service: analysis of 19,382 dispatches
  20. 7780
    “…Tricuspid valve replacement, mitral valve repair, and a closure of the patent foramen ovale (PFO) were conducted. Two months later, hemicolectomy and liver segment resection were performed. …”
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    Carcinoid heart disease involving the left heart: a case report and biomarker analysis
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