“…Mechanistically, LRIG2 has the ability to physically interact with PDGFRβ, promoting the total expression and the activation of PDGFRβ, and enhancing its downstream signaling pathways of Akt and signal transducer and activator of transcription 3 and the effectors of key regulators of cell cycle progression, resulting in increased GBM cell proliferation. …”
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“…From the 15 significantly associated SNPs, 146 genes containing or physically close to these loci were identified as putative reniform nematode resistance candidate genes. …”
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“…BACKGROUND: Physicians and physicists are expected to contribute to patient safety and quality improvement (QI) in Radiation Oncology (RO), but prior studies suggest that training for this may be inadequate. RO and medical physics (MP) program directors (PDs) were surveyed to better understand the current patient safety/QI training in their residency programs. …”
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“…The meta-analysis revealed significant associations with heavy physically demanding work (odds ratio [OR] 2.03, 95% confidence interval [CI] 1.48–2.79), bending or twisting of the trunk (OR 2.43, 95% CI 1.67–3.55), and lifting and carrying in combination with bending or twisting of the trunk (OR 2.84, 95% CI 2.18–3.69). …”
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“…Named Proximity-Sequencing (Pro-Seq), the method merges multiple copies of each template into a single sequencing read by physically linking the molecular copies so they seed a single sequencing cluster. …”
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“…RESULTS: Both male and female workers in physically demanding occupations were more likely to report poor health. …”
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“…Besides, bile acids may withstand the gastrointestinal impediments and aid in the transporter-mediated absorption of physically complexed or chemically conjugated drug molecules. …”
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“…The truck driver sample was less physically active and had lower HDL cholesterol along with greater levels of smoking, BMI, and metabolic syndrome diagnosis. …”
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“…Studies are now needed in which choices are made between physically-present foods. ELECTRONIC SUPPLEMENTARY MATERIAL: The online version of this article (10.1186/s12889-018-6112-3) contains supplementary material, which is available to authorized users.…”
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“…In the proposed method, we classify each A-line, a datum element that better captures physics and pathophysiology than a voxel, as a fibrous layer followed by calcification (fibrocalcific), a fibrous layer followed by a lipidous deposit (fibrolipidic), or other. …”
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“…These findings demonstrate that exposition of healthy humans to the physically challenging extreme environment of Antarctica (i) has a distinct modulating effect on stress responses. …”
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“…Software calculation is based on a physics model of the image acquisition process and incorporates the effect of masking in DM based on accumulated dense tissue areas. …”
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“…Further studies showed that TRIB2 physically interacted with AP4 and inhibited p21 expression through enhancing transcription activities of AP4. …”
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“…At the same time ab initio calculations have added value compared to force fields, as they provide a physically more sound description of the adsorption mechanism and in some cases clearly improve correspondence with experiment.…”
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“…In C. albicans, Mfg1 also interacts physically with Flo8 and Mss11 and is critical for filamentation in response to diverse cues, but the mechanisms through which it regulates morphogenesis remained elusive. …”
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“…Innovations in laser technology and advances in various other spheres of applied physics have been capitalized upon to evolve the next generation OT systems. …”
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“…To assess whether a battery of performance markers, both individually and as group, would be sensitive to fatigue, a within group random cross-over design compared multiple variables during seated control and fatigue (repeated sprint cycling) conditions. Thirty-two physically active participants completed a neuromuscular fatigue questionnaire, Stroop task, postural sway, squat jump, countermovement jump, isometric mid-thigh pull and 10 s maximal sprint cycle (Sprint(max)) before and after each condition (15 min, 1 h, 24 h and 48 h). …”
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“…RESULTS: We identified 313 cases, majority of which were female, reported poor overall health, physically inactivity and experienced respiratory symptoms within the previous year. …”
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“…A player must learn how to physically reproduce a target pitch, but before that, the player must learn what correct intonation is. …”
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“…Improved RGD‐alginate hydrogel was physically characterised and assessed for cell viability to serve as a generic 3D culture system for human pluripotent stem cells (hPSCs) and neuronal cells. …”
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