“…In this review, we will focus on the synthesis, molecular-design strategies, and bioimaging applications of tetrazine-functionalized fluorogenic probes. Traditional Pinner reaction and “Pinner-like” reactions for tetrazine synthesis are discussed here, as well as metal-catalyzed C–C bond formations with convenient tetrazine intermediates and the fabrication of tetrazine-conjugated fluorophores. …”
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“…This article explores the experience of illness among physicians by applying an historical, narratological approach to three doctor’s narratives about personal cases of cardiac disease: Max Pinner’s from the 1940s, Robert Seaver’s from the 1980s, and John Mulligan’s from 2015. …”
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“…The efficiency of the crosslinking by electron beam irradiation was analyzed by Charlesby–Pinner parameter evaluation and crosslink density measurements. …”
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“…[Image: see text] Facile synthesis for Dabigatran etexilate mesylate (1), an anticoagulant drug, is reported using a novel synthon, n-hexyl-4-nitrophenyl carbonate (32), which substantially eliminates the formation of potential impurities 20–27, which were generated due to the use of n-hexyl chloroformate in previously reported methods. Pinner reaction to prepare a key and critical intermediate, amidine 8, was optimized using design of experiment software to establish critical process parameters to achieve 8 in 97% yield. …”
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“…Analyzing the behavior of the irradiation samples using the Charlesby–Pinner equation, it is observed that all the samples tend to crosslink by irradiation, the share of degradation reactions being low. …”
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“…Different amidine synthesis methodologies namely, lithium bis-trimethylsilylamide (LiN[Si(CH3)(3)](2)) and Pinner methods were used to prepare the diamidines. …”
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“…The greatest change in the surface free energy and the contact angles occurs at an irradiation dose of 20 kGy. The Charlesby–Pinner plots prove the tendency to crosslinking as the irradiation dose increases.…”
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“…We calculated global and local Moran’s I-statistics to identify spatial clustering of districts with high MM incidence. We used a Pinner model to estimate the impact of vaccination campaigns occurring between 2015 and 2017 and to evaluate the impact of 3 alternative district-level vaccination strategies, compared with that currently used. …”
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“…The curing assay and Charlesby–Pinner representation as well as the modifications that occurred in the FTIR carbonyl band at 1745 cm(−1) are appropriate proofs for the delay of oxidation in hybrid samples. …”
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“…CONCLUSIONS: Although popular pinners tended to post recipes with more seafood or poultry or vegetables and less meat, recipes with higher fat and sugar content were more user-engaging, with more photo or video shares and comments. …”
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