Mostrando 201 - 220 Resultados de 1,200 Para Buscar '"Pirna"', tiempo de consulta: 0.16s Limitar resultados
  1. 201
    “…These RNAs are expressed in the gonad, which we hypothesize to trigger production of piRNAs for control of transposable elements (TEs). …”
    Enlace del recurso
    Enlace del recurso
    Enlace del recurso
    Online Artículo Texto
    siRNAs and piRNAs collaborate for transposon control in the two-spotted spider mite
  2. 202
    “…The piRNA pathway is a surveillance system that guarantees oogenesis and adult fertility in a range of animal species. …”
    Enlace del recurso
    Enlace del recurso
    Enlace del recurso
    Online Artículo Texto
    Transcriptomic and functional analyses of the piRNA pathway in the Chagas disease vector Rhodnius prolixus
  3. 203
    “…In Caenorhabditis elegans, most piRNA precursors are transcribed from two genomic clusters that contain thousands of individual piRNA transcription units. …”
    Enlace del recurso
    Enlace del recurso
    Enlace del recurso
    Online Artículo Texto
    The USTC co-opts an ancient machinery to drive piRNA transcription in C. elegans
  4. 204
    “…PIWI-interacting RNAs (piRNAs) are small non-coding RNAs that partner with PIWI proteins to protect germline tissues from destabilizing transposon activity. …”
    Enlace del recurso
    Enlace del recurso
    Enlace del recurso
    Online Artículo Texto
    piRNA-8041 is downregulated in human glioblastoma and suppresses tumor growth in vitro and in vivo
  5. 205
    “…The piRNA pathway is an adaptive mechanism that maintains genome stability by repression of selfish genomic elements. …”
    Enlace del recurso
    Enlace del recurso
    Enlace del recurso
    Online Artículo Texto
    piRNA silencing contributes to interspecies hybrid sterility and reproductive isolation in Drosophila melanogaster
  6. 206
    “…The Piwi-interacting RNA (piRNA) pathway is a small RNA-based immune system that silences mobile genetic elements in animal germlines. piRNA biogenesis requires a specialized machinery that converts long single-stranded precursors into small RNAs of ∼25-nucleotides in length. …”
    Enlace del recurso
    Enlace del recurso
    Enlace del recurso
    Online Artículo Texto
    Daedalus and Gasz recruit Armitage to mitochondria, bringing piRNA precursors to the biogenesis machinery
  7. 207
    por Mendel, Mateusz, Pillai, Ramesh S.
    Publicado 2019
    “…Their findings reveal the sequence of events leading from its role at the site of transcription to delivery of the cargo to cytoplasmic piRNA biogenesis sites.…”
    Enlace del recurso
    Enlace del recurso
    Enlace del recurso
    Online Artículo Texto
    Nxf3: a middleman with the right connections for unspliced piRNA precursor export
  8. 208
    por Hirakata, Shigeki, Siomi, Mikiko C.
    Publicado 2019
    “…PIWI-interacting RNAs (piRNAs) are small non-coding RNAs that repress transposons in animal germlines. …”
    Enlace del recurso
    Enlace del recurso
    Enlace del recurso
    Online Artículo Texto
    Assembly and Function of Gonad-Specific Non-Membranous Organelles in Drosophila piRNA Biogenesis
  9. 209
    “…In the fetal mouse testis, PIWI Interacting RNAs (piRNAs) guide PIWI proteins to silence transposons, but after birth, most post-pubertal pachytene piRNAs map to the genome uniquely and are thought to regulate genes required for male fertility. …”
    Enlace del recurso
    Enlace del recurso
    Enlace del recurso
    Online Artículo Texto
    Evolutionarily Conserved Pachytene piRNA Loci are Highly Divergent among Modern Humans
  10. 210
    por Kofler, Robert
    Publicado 2020
    “…piRNA clusters are thought to repress transposable element (TE) activity in mammals and invertebrates. …”
    Enlace del recurso
    Enlace del recurso
    Enlace del recurso
    Online Artículo Texto
    piRNA Clusters Need a Minimum Size to Control Transposable Element Invasions
  11. 211
    “…PIWI-interacting RNAs (piRNAs) associate with PIWI proteins, form effector complexes and maintain genome integrity and function in the regulation of gene expression by epigenetic modifications. …”
    Enlace del recurso
    Enlace del recurso
    Enlace del recurso
    Online Artículo Texto
    PIWIL-2 and piRNAs are regularly expressed in epithelia of the skin and their expression is related to differentiation
  12. 212
    por Wang, Chen, Lin, Haifan
    Publicado 2021
    “…PIWI proteins, a subfamily of PAZ/PIWI Domain family RNA-binding proteins, are best known for their function in silencing transposons and germline development by partnering with small noncoding RNAs called PIWI-interacting RNAs (piRNAs). However, recent studies have revealed multifaceted roles of the PIWI-piRNA pathway in regulating the expression of other major classes of RNAs in germ cells. …”
    Enlace del recurso
    Enlace del recurso
    Enlace del recurso
    Online Artículo Texto
    Roles of piRNAs in transposon and pseudogene regulation of germline mRNAs and lncRNAs
  13. 213
    “…SIMPLE SUMMARY: Although ovarian cancer (OC) is one of the most lethal gynecological cancers, its development and progression remain poorly understood. The piRNA pathway is important for transposon defense and genome stability. piRNA maturation and function involve a number of genes known as the piRNA pathway genes. …”
    Enlace del recurso
    Enlace del recurso
    Enlace del recurso
    Online Artículo Texto
    A Comprehensive Molecular and Clinical Analysis of the piRNA Pathway Genes in Ovarian Cancer
  14. 214
    “…piRNAs are small non-coding RNAs required to maintain genome integrity and preserve RNA homeostasis during male gametogenesis. …”
    Enlace del recurso
    Enlace del recurso
    Enlace del recurso
    Online Artículo Texto
    Sperm acrosome overgrowth and infertility in mice lacking chromosome 18 pachytene piRNA
  15. 215
    “…By systematically screening piRNA profiles in sperms of normozoospermic men and asthenozoospermia patients, we found that piRNAs were parallelly reduced during infertility. …”
    Enlace del recurso
    Enlace del recurso
    Enlace del recurso
    Online Artículo Texto
    Decreased piRNAs in Infertile Semen Are Related to Downregulation of Sperm MitoPLD Expression
  16. 216
    “…C. elegans piRNAs (21U RNAs) are transcribed individually from minigenes as precursors that require 5′ and 3′ processing. …”
    Enlace del recurso
    Enlace del recurso
    Enlace del recurso
    Online Artículo Texto
    Structural basis of PETISCO complex assembly during piRNA biogenesis in C. elegans
  17. 217
    “…PIWI‐interacting RNAs (piRNAs) are germline‐specific small RNAs that form effector complexes with PIWI proteins (Piwi–piRNA complexes) and play critical roles for preserving genomic integrity by repressing transposable elements (TEs). …”
    Enlace del recurso
    Enlace del recurso
    Enlace del recurso
    Online Artículo Texto
    Piwi–piRNA complexes induce stepwise changes in nuclear architecture at target loci
  18. 218
    “…In most species, the majority of piRNAs are produced from distinct large genomic loci, called piRNA clusters. …”
    Enlace del recurso
    Enlace del recurso
    Enlace del recurso
    Online Artículo Texto
    Large Drosophila germline piRNA clusters are evolutionarily labile and dispensable for transposon regulation
  19. 219
    “…PIWI-interacting RNAs (piRNAs) and their partnering PIWI proteins defend the animal germline against transposable elements and play a crucial role in fertility. …”
    Enlace del recurso
    Enlace del recurso
    Enlace del recurso
    Online Artículo Texto
    piRNAclusterDB 2.0: update and expansion of the piRNA cluster database
  20. 220
    “…In addition, this article discusses the potential clinical usefulness of piRNAs as biomarkers and therapeutic targets in GI cancers. …”
    Enlace del recurso
    Enlace del recurso
    Enlace del recurso
    Online Artículo Texto
    The Emerging Role of PIWI-Interacting RNAs (piRNAs) in Gastrointestinal Cancers: An Updated Perspective
Herramientas de búsqueda: RSS