Mostrando 401 - 420 Resultados de 1,200 Para Buscar '"Pirna"', tiempo de consulta: 0.23s Limitar resultados
  1. 401
    “…Piwi-interacting RNAs (piRNAs) are important for genome regulation across metazoans, but their biogenesis evolves rapidly. …”
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    Comparative Epigenomics Reveals that RNA Polymerase II Pausing and Chromatin Domain Organization Control Nematode piRNA Biogenesis
  2. 402
    “…In the metazoan germline, their mobilization is limited by a class of small RNAs called PIWI-interacting RNAs (piRNAs) produced by dedicated genomic loci called piRNA clusters. …”
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    Trapping a somatic endogenous retrovirus into a germline piRNA cluster immunizes the germline against further invasion
  3. 403
    “…BACKGROUND: PIWI-interacting RNAs (piRNAs) are the effectors of transposable element silencing in the reproductive apparatus. …”
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    flam piRNA precursors channel from the nucleus to the cytoplasm in a temporally regulated manner along Drosophila oogenesis
  4. 404
    “…Piwi‐interacting RNAs (piRNAs) are thought to be germline‐specific and to be involved in maintaining genome stability during development. …”
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    piRNA‐63076 contributes to pulmonary arterial smooth muscle cell proliferation through acyl‐CoA dehydrogenase
  5. 405
    “…What marks pachytene piRNA clusters to produce piRNAs, and what confines their expression to the germline? …”
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    Long first exons and epigenetic marks distinguish conserved pachytene piRNA clusters from other mammalian genes
  6. 406
    “…Piwi-interacting RNAs (piRNAs) play essential roles in silencing repetitive elements to promote fertility in metazoans. …”
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    SNPC-1.3 is a sex-specific transcription factor that drives male piRNA expression in C. elegans
  7. 407
    “…PIWI‐interacting RNAs (piRNAs) are genome‐encoded small RNAs that regulate germ cell development and maintain germline integrity in many animals. …”
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    The RNA polymerase II subunit RPB‐9 recruits the integrator complex to terminate Caenorhabditis elegans piRNA transcription
  8. 408
    “…In this study, differentially expressed (DE) PIWI-interacting RNAs (piRNAs) of fresh and frozen-thawed sperm with different freeze tolerance capacity from giant panda and boar were evaluated. …”
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    Comparative Analysis of piRNA Profiles Helps to Elucidate Cryoinjury Between Giant Panda and Boar Sperm During Cryopreservation
  9. 409
    “…Recent evidence highlights piRNAs to regulate genes via a miRNA‐like mechanism. …”
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    Candidate l‐methionine target piRNA regulatory networks analysis response to cocaine‐conditioned place preference in mice
  10. 410
    “…However, there is no systematic understanding of the piRNA binding patterns and how piRNA targets genes. …”
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    Identifying piRNA targets on mRNAs in C. elegans using a deep multi-head attention network
  11. 411
    “…Silencing of transposable elements (TEs) by Piwi-interacting RNAs (piRNAs) is crucial for maintaining germline genome integrity and fertility in animals. …”
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    The Tudor Domain-Containing Protein, Kotsubu (CG9925), Localizes to the Nuage and Functions in piRNA Biogenesis in D. melanogaster
  12. 412
    “…We explored candidate genes with nucleotide repeats to predict associations with miRNAs and piRNAs. The parameters of miRNAs and piRNA binding sites with mRNAs of human genes having nucleotide repeats were determined using the MirTarget program. …”
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    Bioinformatics Analysis of the Interaction of miRNAs and piRNAs with Human mRNA Genes Having di- and Trinucleotide Repeats
  13. 413
    “…We did not detect FKBP6 as part of the SC in normal human spermatocytes, but small RNA sequencing revealed that loss of FKBP6 severely impacted piRNA levels, supporting a role for FKBP6 in piRNA biogenesis in humans. …”
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    The piRNA-pathway factor FKBP6 is essential for spermatogenesis but dispensable for control of meiotic LINE-1 expression in humans
  14. 414
    “…The piRNA pathway is a conserved germline-specific small RNA pathway that ensures genomic integrity and continued fertility. …”
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    The Upstream Sequence Transcription Complex Dictates Nucleosome Positioning and Promoter Accessibility at piRNA Genes in the C. elegans Germ Line
  15. 415
    “…Recent studies showed that small interfering RNAs (siRNAs) and Piwi-interacting RNA (piRNA) in mammalian germ cells play important roles in retrotransposon silencing and gametogenesis. …”
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    Small RNA class transition from siRNA/piRNA to miRNA during pre-implantation mouse development
  16. 416
    “…Piwi-interacting RNAs (piRNAs) are known to regulate transposon activity in germ cells of several animal models that propagate sexually. …”
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    Expansion of Genes Encoding piRNA-Associated Argonaute Proteins in the Pea Aphid: Diversification of Expression Profiles in Different Plastic Morphs
  17. 417
    “…The chromosomal density of hypermethylated LINE-1 elements had a significant positive correlation with the chromosomal density of piRNA genes (r = 0.41, P = 0.05). Genome windows of 1-16 Mb containing piRNA clusters had significantly more hypermethylated LINE-1 elements than windows not containing piRNA clusters. …”
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    The distribution of a germline methylation marker suggests a regional mechanism of LINE-1 silencing by the piRNA-PIWI system
  18. 418
    “…PIWI-interacting RNAs (piRNAs) provide defence against transposable element (TE) expansion in the germ line of metazoans. piRNAs are processed from the transcripts encoded by specialized heterochromatic clusters enriched in damaged copies of transposons. …”
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    De novo piRNA cluster formation in the Drosophila germ line triggered by transgenes containing a transcribed transposon fragment
  19. 419
    por Sagy, Or, Shamir, Ron, Rechavi, Oded
    Publicado 2014
    “…These results might help understanding why most piRNAs in C. elegans are physically clustered on particular loci on chromosome IV. …”
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    Examination of exhaustive cloning attempts reveals that C. elegans piRNAs, transposons, and repeat sequences are efficiently cloned in yeast, but not in bacteria
  20. 420
    “…Unusually, many TEs and the 3’UTR of some endogenous genes produce an abundant peak of 29-nt small RNAs with piRNA-like characteristics. Moreover, both sense and antisense piRNAs from TEs in both Anopheles gambiae and Drosophila melanogaster reveal novel features of piRNA sequence bias. …”
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    The germline of the malaria mosquito produces abundant miRNAs, endo-siRNAs, piRNAs and 29-nt small RNAs
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