Mostrando 481 - 500 Resultados de 1,200 Para Buscar '"Pirna"', tiempo de consulta: 0.50s Limitar resultados
  1. 481
    “…Additionally, we analyzed the data sets for piRNAs, lncRNAs, circRNAs, and sno/mt-RNAs. We validated the in silico data using human HCC samples with NanoString miRNA global expression. …”
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    Non-coding RNAs in Various Stages of Liver Disease Leading to Hepatocellular Carcinoma: Differential Expression of miRNAs, piRNAs, lncRNAs, circRNAs, and sno/mt-RNAs
  2. 482
    “…Motivation: PIWI-interacting RNAs (piRNAs), 23–36 nt small silencing RNAs, repress transposon expression in the metazoan germ line, thereby protecting the genome. …”
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    piPipes: a set of pipelines for piRNA and transposon analysis via small RNA-seq, RNA-seq, degradome- and CAGE-seq, ChIP-seq and genomic DNA sequencing
  3. 483
    “…ABSTRACT: Maelstrom (MAEL) plays a crucial role in a recently-discovered piRNA pathway; however its specific function remains unknown. …”
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    Functional insight into Maelstrom in the germline piRNA pathway: a unique domain homologous to the DnaQ-H 3'–5' exonuclease, its lineage-specific expansion/loss and evolutionarily active site switch
  4. 484
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    The Role of Nucleases Cleaving TLR3, TLR7/8 and TLR9 Ligands, Dicer RNase and miRNA/piRNA Proteins in Functional Adaptation to the Immune Escape and Xenophagy of Prostate Cancer Tissue
  5. 485
    “…First, by sequencing EV derived miRNAs and piRNAs we found that EVs contain RNAs able to influence UCB-CD34+ cell fate. …”
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    MiRNAs and piRNAs from bone marrow mesenchymal stem cell extracellular vesicles induce cell survival and inhibit cell differentiation of cord blood hematopoietic stem cells: a new insight in transplantation
  6. 486
    “…Transgenic piRNA clusters are not established in piRNA pathway mutants. …”
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    Epigenetic Requirements for Triggering Heterochromatinization and Piwi-Interacting RNA Production from Transgenes in the Drosophila Germline
  7. 487
    “…But the precise mechanism of piRNA in CC is still unknown. In our study, we found that piRNA-17458 was overexpressed in CC tissues and cells. piRNA-17458 mimic and inhibitor promoted and suppressed proliferation, migration and invasion ability of CC cells, respectively. …”
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    PIWI-interacting RNA-17458 is oncogenic and a potential therapeutic target in cervical cancer
  8. 488
    “…The pcDNA vector containing piRNA-31106 (pcDNA-piRNA-31106) and a short hairpin (sh)RNA containing piRNA-31106 (shRNA-piRNA-31106) were used to interfere with piRNA-31106 expression in breast cancer cells. …”
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    In vitro study of piwi interaction RNA-31106 promoting breast carcinogenesis by regulating METTL3-mediated m6A RNA methylation
  9. 489
    “…PIWI interacting RNAs (piRNAs) have emerged as important gene regulators in recent times. …”
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    piRNAQuest V.2: an updated resource for searching through the piRNAome of multiple species
  10. 490
    “…PIWI-interacting RNAs (piRNAs) are germline-specific small non-coding RNAs that form piRNA-induced silencing complexes (piRISCs) by associating with PIWI proteins, a subclade of the Argonaute proteins predominantly expressed in the germline. piRISCs protect the integrity of the germline genome from invasive transposable DNA elements by silencing them. …”
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    Gender-Specific Hierarchy in Nuage Localization of PIWI-Interacting RNA Factors in Drosophila
  11. 491
    “…Bombyx mori BmN4 cells are culturable germ cells that equip the piRNA pathway. Because of the scarcity of piRNA-expressing culturable cells, BmN4 cells are being utilized for the analyses of piRNA biogenesis. …”
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    Increasing cell density globally enhances the biogenesis of Piwi-interacting RNAs in Bombyx mori germ cells
  12. 492
    “…The piRNA pathway protects germline genomes from selfish genetic elements (e.g. transposons) through their transcript cleavage in the cytoplasm and/or their transcriptional silencing in the nucleus. …”
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    A kinesin Klp10A mediates cell cycle-dependent shuttling of Piwi between nucleus and nuage
  13. 493
    “…These piRNAs launch a cycle of TE and piRNA cluster transcript cleavages resulting in the amplification of piRNA and TE silencing. …”
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    Euchromatic Transposon Insertions Trigger Production of Novel Pi- and Endo-siRNAs at the Target Sites in the Drosophila Germline
  14. 494
    “…Our results revealed that female-specific piRNA precursors, which we named Fem, are transcribed from the sex-determining region of the W chromosome at the early embryonic stage and are processed into a single mature piRNA (Fem piRNA). …”
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    Guardian small RNAs and sex determination
  15. 495
    “…An abundance of piRNAs was detected in both skin and oral mucosal epithelium during wound healing. …”
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    Site-Specific Expression Pattern of PIWI-Interacting RNA in Skin and Oral Mucosal Wound Healing
  16. 496
    por Scarpa, Almorò, Kofler, Robert
    Publicado 2023
    “…According to the prevailing view, the trap model, the activity of invading transposable elements (TEs) is greatly reduced when a TE copy jumps into a piRNA cluster, which triggers the emergence of piRNAs that silence the TE. …”
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    The impact of paramutations on the invasion dynamics of transposable elements
  17. 497
    por Li, Yinuo, Zhang, Yue, Liu, Mingxi
    Publicado 2021
    “…The PIWI-interacting RNA (piRNA) pathway mainly consists of evolutionarily conserved protein factors. …”
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    Knockout Gene-Based Evidence for PIWI-Interacting RNA Pathway in Mammals
  18. 498
    “…PIWI proteins and their associated piRNAs protect germ cells from the activity of mobile genetic elements. …”
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    RNF17 blocks promiscuous activity of PIWI proteins in mouse testes
  19. 499
    “…The mouse PIWI-interacting RNA (piRNA) pathway produces a class of 26–30-nucleotide (nt) small RNAs and is essential for spermatogenesis and retrotransposon repression. …”
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    Roles of MIWI, MILI and PLD6 in small RNA regulation in mouse growing oocytes
  20. 500
    “…PIWI-interacting RNAs (piRNAs) are an emerging class of non-coding RNAs involved in tumorigenesis. …”
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    Systematic evaluation of the effects of genetic variants on PIWI-interacting RNA expression across 33 cancer types
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