Mostrando 1 - 20 Resultados de 1,200 Para Buscar '"Pirna"', tiempo de consulta: 0.18s Limitar resultados
  1. 1
    “…Piwi-interacting RNAs (piRNAs) originate from genomic regions dubbed piRNA clusters. …”
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    To be or not to be a piRNA: genomic origin and processing of piRNAs
  2. 2
    “…On the other hand, with the same treatment we could not detect significant changes in levels or subcellular distribution (nuage localization) of piRNA precursor transcripts. This shows that Cbp80 plays an important role in the production and localization of the protein components of the piRNA pathway and it seems to be less important for the production and export of the piRNA precursor transcripts.…”
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    Cbp80 is needed for the expression of piRNA components and piRNAs
  3. 3
    “…P-element induced wimpy testis-interacting RNAs (piRNAs) are essential for testicular development and spermatogenesis in mammals. …”
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    Identification of piRNAs and piRNA clusters in the testes of the Mongolian horse
  4. 4
    “…In Drosophila, the genomic regions that give rise to piRNAs, the so-called piRNA clusters, are transcribed to generate long precursor molecules that are processed into mature piRNAs. …”
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    Transgenerationally inherited piRNAs trigger piRNA biogenesis by changing the chromatin of piRNA clusters and inducing precursor processing
  5. 5
    por Sun, Yu H., Lee, Brent, Li, Xin Zhiguo
    Publicado 2021
    “…PIWI-interacting RNAs (piRNAs), small noncoding RNAs 24–35 nucleotides long, are essential for animal fertility. …”
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    The birth of piRNAs: how mammalian piRNAs are produced, originated, and evolved
  6. 6
    “…In the reproductive tissues of a large range of organisms, they are repressed by a subclass of small interfering RNAs called piRNAs (PIWI interacting RNAs). In Drosophila melanogaster, piRNAs are produced both in the ovarian germline cells and in their surrounding somatic cells. …”
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    Distinct features of the piRNA pathway in somatic and germ cells: from piRNA cluster transcription to piRNA processing and amplification
  7. 7
    por Zhang, Yi, Wang, Xianhui, Kang, Le
    Publicado 2011
    “…Motivation: Identifying piwi-interacting RNAs (piRNAs) of non-model organisms is a difficult and unsolved problem because piRNAs lack conservative secondary structure motifs and sequence homology in different species. …”
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    A k-mer scheme to predict piRNAs and characterize locust piRNAs
  8. 8
    por Rosenkranz, David
    Publicado 2016
    “…A substantial fraction of piRNAs originates from genomic loci termed piRNA clusters and sequences encoded in these piRNA clusters determine putative targets for the Piwi/piRNA system. …”
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    piRNA cluster database: a web resource for piRNA producing loci
  9. 9
    “…PIWI-interacting RNAs (piRNAs) are a class of small non-coding RNAs essential for fertility. …”
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    Ribosomes guide pachytene piRNA formation on long intergenic piRNA precursors
  10. 10
    “…A vast proportion of piRNAs is produced from discrete genomic loci, termed piRNA clusters, which are generally embedded in heterochromatic regions. …”
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    The Cutoff protein regulates piRNA cluster expression and piRNA production in the Drosophila germline
  11. 11
    por Izumi, Natsuko, Tomari, Yukihide
    Publicado 2014
    “…The PIWI-interacting RNA (piRNA) pathway protects animal germline cells from transposable elements and other genomic invaders. …”
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    Diversity of the piRNA pathway for nonself silencing: worm-specific piRNA biogenesis factors
  12. 12
    por Kawase, Masaki, Ichiyanagi, Kenji
    Publicado 2022
    “…In mammals, germ cells produce a class of small regulatory RNAs called PIWI-interacting RNAs or piRNAs, which are 25–32 nucleotides in length. The profile of testicular piRNAs changes during development. …”
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    The Expression Dynamics of piRNAs Derived From Male Germline piRNA Clusters and Retrotransposons
  13. 13
    “…Piwi-interacting RNAs (piRNAs) ensure transposable element silencing in Drosophila, thereby preserving genome integrity across generations. …”
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    Profiles of piRNA abundances at emerging or established piRNA loci are determined by local DNA sequences
  14. 14
    “…Pachytene piRNAs are the most abundant piRNAs in mammalian adult testes. …”
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    TDRD5 binds piRNA precursors and selectively enhances pachytene piRNA processing in mice
  15. 15
    “…In Drosophila ovarian somatic cells, PIWI-interacting small RNAs (piRNAs) against transposable elements are mainly produced from the ∼180-kb flamenco (flam) locus. flam transcripts are gathered into foci, located close to the nuclear envelope, and processed into piRNAs in the cytoplasmic Yb bodies. …”
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    Yb body assembly on the flamenco piRNA precursor transcripts reduces genic piRNA production
  16. 16
    “…Piwi-interacting RNAs (piRNAs) have been indicated to serve important roles in spermatogenesis. …”
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    Seminal plasma piRNA array analysis and identification of possible biomarker piRNAs for the diagnosis of asthenozoospermia
  17. 17
    “…Historically, piRNAs have been shown to be indispensable in germline integrity and stem cell development. …”
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    piRNAs as Modulators of Disease Pathogenesis
  18. 18
    “…Piwi–piRNA (Piwi-interacting RNA) ribonucleoproteins (piRNPs) enforce retrotransposon silencing, a function critical for preserving the genome integrity of germ cells. …”
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    The RNA helicase MOV10L1 binds piRNA precursors to initiate piRNA processing
  19. 19
    “…The sheer number of piRNA cluster (piC) loci in animal genomes and infrequent piRNA sequence conservation also present challenges in determining which piC loci are most important for development. …”
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    Conserved piRNA Expression from a Distinct Set of piRNA Cluster Loci in Eutherian Mammals
  20. 20
    “…The bulk of pachytene piRNAs is produced from large genomic loci, named piRNA clusters. …”
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    Primate piRNA Cluster Evolution Suggests Limited Relevance of Pseudogenes in piRNA-Mediated Gene Regulation
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