Mostrando 141 - 160 Resultados de 4,339 Para Buscar '"Prion"', tiempo de consulta: 0.58s Limitar resultados
  1. 141
    “…BACKGROUND: Contagious prion diseases – scrapie of sheep and chronic wasting disease of several species in the deer family – give rise to epidemics that seem capable of compromising host population viability. …”
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  2. 142
    por Chiesa, Roberto, Harris, David A
    Publicado 2009
    “…The prion protein is infamous for its role in devastating neurological diseases, but its normal, physiological function has remained mysterious. …”
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  3. 143
    “…Eleven (1.8%) of 597 patients underwent ophthalmic surgery within 1 month before the onset of prion disease or after the onset. All ophthalmologists reused surgical instruments that had been incompletely sterilized to eliminate infectious prion protein. …”
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  4. 144
  5. 145
    “…Prions arise when the cellular prion protein (PrP(C)) undergoes a self-propagating conformational change; the resulting infectious conformer is designated PrP(Sc). …”
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  6. 146
    por Imran, Muhammad, Mahmood, Saqib
    Publicado 2011
    “…Prion diseases are transmissible neurodegenerative conditions affecting human and a wide range of animal species. …”
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  7. 147
    por Imran, Muhammad, Mahmood, Saqib
    Publicado 2011
    “…Prion diseases are transmissible, progressive and invariably fatal neurodegenerative conditions associated with misfolding and aggregation of a host-encoded cellular prion protein, PrP(C). …”
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  8. 148
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  10. 150
    “…In fungi, prions are not pathogenic but rather act as epigenetic regulators of cell physiology, providing a powerful model for studying the mechanism of prion replication. …”
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  11. 151
    “…In contrast, Tg mice expressing OvPrP with valine (V) at 136 (OvPrP-V136) infected with the same prions developed disease rapidly, and the converted prion was comprised of an unstable (U), diffusely distributed conformer. …”
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  12. 152
    por Hofmann, Julia, Vorberg, Ina
    Publicado 2013
    “…Prions are self-templating protein aggregates that were originally identified as the causative agent of prion diseases in mammals, but have since been discovered in other kingdoms. …”
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  13. 153
    por Telling, Glenn C
    Publicado 2004
    “…Studies of mammalian prion diseases such as bovine spongiform encephalopathy have suggested that different strains consist of prion proteins with different conformations. …”
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  14. 154
    “…The deletion of the cellular form of the prion protein (PrP(C)) in mouse, goat, and cattle has no drastic phenotypic consequence. …”
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  15. 155
  16. 156
    “…Bovine spongiform encephalopathy (BSE) is a prion disease that is invariably fatal in cattle and has been implicated as a significant human health risk. …”
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  17. 157
    por Hammarström, Per, Nyström, Sofie
    Publicado 2015
    “…Mammalian prions are composed of misfolded aggregated prion protein (PrP) with amyloid-like features. …”
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  18. 158
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  20. 160
    “…Transmissible spongiform encephathalopathies or prion diseases are a group of neurological disorders characterized by neuronal loss, spongiform degeneration, and activation of astrocytes or microglia. …”
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