Mostrando 1 - 20 Resultados de 4,339 Para Buscar '"Prion"', tiempo de consulta: 0.21s Limitar resultados
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    por Harbi, Djamel, Harrison, Paul M
    Publicado 2014
    “…The universe of prion and prion-like phenomena has expanded significantly in the past several years. …”
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    “…Similarly, we find that infectious proteins (prions) are severely restricted by an array of host systems, acting independently to prevent infection, generation, propagation and the ill effects of yeast prions. …”
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    “…Prions are units of propagation of an altered state of a protein or proteins; prions can propagate from organism to organism, through cooption of other protein copies. …”
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    “…Prions are unique elements in biology, being able to transmit biological information from one organism to another in the absence of nucleic acids. …”
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    “…These results provide proof of principle that recombinant hamster prion proteins can effectively and safely inhibit prion disease in mice, and suggest that hamster or other non-human prion proteins may be a viable treatment for prion diseases in humans.…”
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    por Verma, Ashok
    Publicado 2016
    “…Prion diseases or transmissible spongiform encephalopathies are fatal neurodegenerative diseases characterized by the aggregation and deposition of the misfolded prion protein in the brain. α-synuclein (α-syn)-associated multiple system atrophy has been recently shown to be caused by a bona fide α-syn prion strain. …”
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    por Song, Zhiqi, Zhao, Deming, Yang, Lifeng
    Publicado 2013
    “…Transmissible spongiform encephalopathy or prion disease is triggered by the conversion from cellular prion protein to pathogenic prion protein. …”
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    “…Last decade witnessed an enormous progress in generating authentic infectious prions or PrP(Sc) in vitro using recombinant prion protein (rPrP). …”
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    por Su, Ting-Yi, Harrison, Paul M.
    Publicado 2019
    “…Here, we have analysed the conservation of sequence and of prion-like composition for prion-forming proteins and for other prion-like proteins from S. cerevisiae, across three evolutionary levels. …”
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    “…BACKGROUND: Prions are transmissible, propagating alternative states of proteins, and are usually made from the fibrillar, beta-sheet-rich assemblies termed amyloid. …”
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    “…In most human sporadic prion diseases the phenotype is consistently associated with specific pairings of the genotype at codon 129 of the prion protein gene and conformational properties of the scrapie PrP (PrP(Sc)) grossly identified types 1 and 2. …”
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    por Mora Forsbach, Rodolfo
    Publicado 2001
    Tesis Libro
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