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Mostrando 141 - 160 Resultados de 244 Para Buscar '"Pro A"', tiempo de consulta: 0.73s Limitar resultados
  1. 141
    “…The steady-state kinetic and deubiquitination activity assays indicated that MERS-CoV PL(pro) exhibits potent deubiquitination activity but lower proteolytic activity, compared with SARS-CoV PL(pro). A natural mutation, Leu105, is the major reason for this difference. …”
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    Structural and functional characterization of MERS coronavirus papain-like protease
  2. 142
    “…URS episode duration and severity were also not influenced by PRO. A significant time × group interaction effect was observed for plasma CMV antibody titres in CMV seropositive participants (p < 0.01) with antibody titre falling in the PRO group but remaining unchanged in the PLA group over time. …”
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    Effects of Lactobacillus casei Shirota ingestion on common cold infection and herpes virus antibodies in endurance athletes: a placebo-controlled, randomized trial
  3. 143
    “…Energy and nutrient intakes were estimated using Nutritionist Pro. A novel recipe-based frequency count coded protein sources as meat (chicken, beef, pork, and mutton), fish, eggs, dairy, and plants (cereals, pulses, tubers). …”
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    Socio-Cultural and Economic Drivers of Plant and Animal Protein Consumption in Malaysia: The SCRiPT Study
  4. 144
    “…One of them showed that folic acid inhibits the furin protease which the virus needs in order to enter its host cell, while the other one explained that folic acid inactivates protease 3CL(pro), a protein that the virus needs to replicate. …”
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    The Folate Concentration and/or Folic Acid Metabolites in Plasma as Factor for COVID-19 Infection
  5. 145
    “…Testing combinations of beneficial substitutions resulted in the identification of HexaPro, a variant with six beneficial proline substitutions exhibiting ~10-fold higher expression than its parental construct and the ability to withstand heat stress, storage at room temperature, and three freeze-thaw cycles. …”
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    Structure-based design of prefusion-stabilized SARS-CoV-2 spikes
  6. 146
    “…When compared with the results of the freezing point depression method used by the OsmoPro, a percentage of the measured urine osmolality by the UF‐5000 was outside the allowable limit.…”
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    Evaluation of conductivity‐based osmolality measurement in urine using the Sysmex UF5000
  7. 147
    “…Moreover, our study demonstrated that the two hit compounds are dual inhibitors targeting the SARS-CoV-2 3-chymotrypsin-like protease (3CL(pro)) in addition to PL(pro). A mechanism of action study using enzyme kinetics further characterized the two compounds as irreversible inhibitors against both 3CL(pro) and PL(pro). …”
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    Online Artículo Texto
    Ginkgolic acid and anacardic acid are specific covalent inhibitors of SARS-CoV-2 cysteine proteases
  8. 148
    “…This study aimed to determine the value of GPSkin Pro, a new handheld device determining both SCH and TEWL, to measure skin barrier impairment and to monitor barrier function in rosacea in daily practice. …”
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    Value of GPSkin for the measurement of skin barrier impairment and for monitoring of rosacea treatment in daily practice
  9. 149
    “…Of the two fragments secreted by P. copri, one abolished the stimulatory effect of E. coli RNA derived from the 3′-UTR of ProA mRNA, while the other inhibited bacterial growth only in the double-stranded state with complementary RNA. …”
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    Suppression of Escherichia coli Growth Dynamics via RNAs Secreted by Competing Bacteria
  10. 150
    “…Recently, main protease (M(pro)), a potential drug target from SARS-CoV-2 has been successfully crystallised. …”
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    Computational assessment of select antiviral phytochemicals as potential SARS-Cov-2 main protease inhibitors: molecular dynamics guided ensemble docking and extended molecular dynamics
  11. 151
    “…Microbiota composition was analyzed with IS-pro, a 16S-23S based bacterial profiling technique. …”
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    Microbiota composition and mucosal immunity in patients with asymptomatic diverticulosis and controls
  12. 152
    “…One possible solution to the present problem is to develop drugs that can inhibit SARS-CoV-2 main protease (M(pro)), a coronavirus protein that been considered as one among many drug targets. …”
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    Identification of lactoferrin-derived peptides as potential inhibitors against the main protease of SARS-CoV-2
  13. 153
    “…One of the most attractive coronaviral drug targets is the main protease (M(pro)). A promising M(pro) inhibitor of clinical relevance is the peptidomimetic nirmatrelvir (PF-07321332). …”
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    Main protease mutants of SARS-CoV-2 variants remain susceptible to nirmatrelvir
  14. 154
    “…PRO intake was further categorized into plant and animal PRO. A multivariate multiple linear regression (MLR) was performed to assess the association between PRO intake and sleep quality. …”
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    Association Between Dietary Protein Intake and Sleep Quality in Middle-Aged and Older Adults in Singapore
  15. 155
    “…For prompt and effective development of antivirals for SARS-CoV-2, the pathogen of COVID-19, drug repurposing has been broadly conducted by targeting the main protease (M(Pro)), a key enzyme responsible for the replication of virus inside the host. …”
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    Repurposing Halicin as a potent covalent inhibitor for the SARS-CoV-2 main protease
  16. 156
    “…In this context, therapies against protease M(pro), a conserved viral target, would be essential to contain the spread of the virus and reduce mortality. …”
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    In silico evidence of antiviral activity against SARS-CoV-2 main protease of oligosaccharides from Porphyridium sp.
  17. 157
    “…The main objective was to evaluate distance, intermediate, and near vision in patients who have undergone cataract extraction with bilateral implantation of a new trifocal diffractive intraocular lens (IOL), along with patient-reported outcomes (PRO). A total of 50 eyes from 25 patients after Asqelio(TM) Trifocal IOL (AST Products, Inc., Billerica MA, USA) implantation were assessed in this study. …”
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    Visual Performance, Satisfaction, and Spectacle Independence after Implantation of a New Hydrophobic Trifocal Intraocular Lens
  18. 158
    “…SARS-CoV-2 3C-like protease (3CL(pro)), a potential therapeutic target for COVID-19, consists of a chymotrypsin fold and a C-terminal α-helical domain (domain III), the latter of which mediates dimerization required for catalytic activation. …”
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    Functional dynamics of SARS-CoV-2 3C-like protease as a member of clan PA
  19. 159
    “…IAnimal (https://ianimal.pro/), a cross-species, multi-omics knowledgebase, was developed to improve the utilization of massive public data and simplify the integration of multi-omics information to mine the genetic mechanisms of objective traits. …”
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    IAnimal: a cross-species omics knowledgebase for animals
  20. 160
    “…This study outlines the functional and nutritional properties of EverPro, a brewer’s spent grain protein, in comparison to commercial plant protein isolates, indicating the potential for the inclusion of new, sustainable plant-based protein sources in human nutrition, in particular dairy alternative applications.…”
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    Functional Properties of Brewer’s Spent Grain Protein Isolate: The Missing Piece in the Plant Protein Portfolio
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