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161por Zhu, Weiwen, Yang, Yi, Jiang, Jiyong, Zhu, Qingtang, Qi, Jian, Qin, Bengang, Fan, Jingyuan, Fu, Ming, Li, Ping“…This study was conducted to evaluate the effectiveness of the FLIR ONE PRO, a thermal imaging camera for smartphones, combined with handheld Doppler (HHD) in the localization of perforator arteries and to assess the efficacy of the FLIR ONE PRO in distinguishing perforators of the descending branch of the lateral circumflex femoral artery (LCFA) from other perforators of the anterolateral thigh perforator (ALTP) flap. …”
Publicado 2023
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162por Wen, Yongqi, Qu, Jinyue, Zhang, Honglin, Yang, Yi, Huang, Rui, Deng, Jili, Zhang, Jiayu, Xiao, Yanping, Li, Jiali, Zhang, Meixin, Wang, Guoping, Zhai, Lifeng“…A papain-like cysteine protease (Pro), a UDP-glucose/sterol glucosyltransferase (UGT), an RNA-dependent RNA polyprotein (RdRp), and a helicase (Hel) were detected in the polyprotein of BdHV1/SXD111. …”
Publicado 2023
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163por Bigham, John M, Rice, Thomas M, Pande, Swati, Lee, Junhak, Park, Shin Hyoung, Gutierrez, Nicolas, Ragland, David R“…Intersection and address geocoding was performed using ArcGIS, StreetMap Pro 2003 digital street network, and Google Earth Pro. A total of 142,007 fatal and severe injury collisions were identified in SWITRS. …”
Publicado 2009
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164por Hou, Yunlong, Sun, Yan, Shan, Hongli, Li, Xuelian, Zhang, Mingyu, Zhou, Xin, Xing, Shu, Sun, Hui, Chu, Wenfeng, Qiao, Guofen, Lu, Yanjie“…RESULTS: Isoproterenol (ISO, a β-adrenoceptor activator) and propranolol (PRO, a β-adrenoceptor inhibitor) induced differential miRNA expression profiles. …”
Publicado 2012
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165por Walsh, Meghaan P., Duncan, Brynn, Larabee, Shannon, Krauss, Aviva, Davis, Jessica P. E., Cui, Yongzhi, Kim, Su Young, Guimond, Martin, Bachovchin, William, Fry, Terry J.“…We investigated the mechanism by which Val-boroPro, a boronic dipeptide that inhibits post-proline cleaving enzymes, mediates tumor regression and tested whether this agent could serve as a novel immune adjuvant to dendritic cell vaccines in two different murine syngeneic murine tumors. …”
Publicado 2013
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166por Reinstadler, Sebastian Johannes, Feistritzer, Hans-Josef, Klug, Gert, Mayr, Agnes, Huybrechts, Luc, Hammerer-Lercher, Angelika, Mair, Johannes, Franz, Wolfgang-Michael, Metzler, Bernhard“…N-terminal pro–B-type natriuretic peptide (NT-proBNP), mid-regional pro–A-type natriuretic peptide (MR-proANP), and mid-regional proadrenomedullin (MR-proADM) levels were measured by established assays. …”
Publicado 2015
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167por de Meij, Tim G. J., de Groot, Evelien F. J., Eck, Anat, Budding, Andries E., Kneepkens, C. M. Frank, Benninga, Marc A., van Bodegraven, Adriaan A., Savelkoul, Paul H. M.“…STUDY DESIGN: Fecal samples from 76 children diagnosed with functional constipation according to the Rome III criteria (median age 8.0 years; range 4.2–17.8) were analyzed by IS-pro, a PCR-based microbiota profiling method. Outcome was compared with intestinal microbiota profiles of 61 healthy children (median 8.6 years; range 4.1–17.9). …”
Publicado 2016
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168“…Lp(a)-HLP associated with progressive CVD has been approved as indication for regular LA in Germany since 2008. The Pro(a)LiFe-study investigated with a prospective multicenter design the long-term preventive effect of LA on incidence rates of cardiovascular events prospectively over a period of 5 years in 170 consecutive patients who commenced regular LA. …”
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169por Schettler, V. J. J., Neumann, C. L., Peter, C., Zimmermann, T., Julius, U., Roeseler, E., Heigl, F., Grützmacher, P., Blume, H., Vogt, A.“…All patients treated by LA showed a median LDL-C reduction rate of 67.5%, and a median Lp (a) reduction rate of 71.1%. Analog to the Pro(a)LiFe pattern, patient data were analyzed to the incidence rate of coronary events (MACE) 1 and 2 years before the beginning of LA treatment (y-2 and y‑1) and prospectively two years on LA treatment (y + 1 and y + 2). …”
Publicado 2017
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170por Lankelma, Jacqueline M., Birnie, Emma, Weehuizen, Tassili A. F., Scicluna, Brendon P., Belzer, Clara, Houtkooper, Riekelt H., Roelofs, Joris J. T. H., de Vos, Alex F., van der Poll, Tom, Budding, Andries E., Wiersinga, W. Joost“…Fecal bacterial composition was analyzed by means of IS-pro, a 16S-23S interspacer region-based profiling method. …”
Publicado 2017
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171por Gottlieb, Alice B., Kirby, Brian, Ryan, Caitriona, Naegeli, April N., Burge, Russel, Potts Bleakman, Alison, Anatchkova, Milena D., Yosipovitch, Gil“…Participants identified and confirmed relevant symptoms and evaluated the utility of the draft PRO. A new PRO was developed: the Genital Psoriasis Symptoms Scale (GPSS). …”
Publicado 2017
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172por White, Richard C., Gunderson, Felizza F., Tyson, Jessica Y., Richardson, Katherine H., Portlock, Theo J., Garnett, James A., Cianciotto, Nicholas P.“…These data revealed, for the first time, the importance of LapA in any sort of infection; thus, we purified LapA and defined its crystal structure, activation by another T2S-dependent protease (ProA), and broad substrate specificity. When the amoebal infection medium was supplemented with amino acids, the defect of the lapA plaC mutant was reversed, implying that LapA generates amino acids for nutrition. …”
Publicado 2018
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173“…OBJECTIVES: To explore that if mid-regional sequence of pro-A-type natriuretic peptide (MR-proANP) may have a good value of diagnosis in heart failure with preserved ejection fraction (HFpEF) compared with N-terminal pro-B-type natriuretic peptide (NT-proBNP). …”
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174“…Instead, the two progressive cleavage products of proNGF were produced, proA-NGF and proB-NGF, with proB-NGF being the predominant NGF-derived peptide and the only peptide secreted by mutant p.R121W cells. …”
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175por Panaro, Brandon L., Coppage, Andrew L., Beaudry, Jacqueline L., Varin, Elodie M., Kaur, Kirandeep, Lai, Jack H., Wu, Wengen, Liu, Yuxin, Bachovchin, William W., Drucker, Daniel J.“…We also assessed the FAP-dependence of CPD60 and talabostat (Val-boroPro), a chemical inhibitor reportedly targeting both FAP and dipeptidyl peptidase-4 RESULTS: CPD60 robustly inhibited plasma FAP activity with no effect on DPP-4 activity. …”
Publicado 2018
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176“…For MDM2 SNP309, the pooled odds ratio (OR) from 15 independent studies with a total of 4038 cases and 5491 controls suggested a significant association for the variant with HCC risk [allele model, G vs T: pooled OR = 1.48, 95% confidence interval (95% CI) = 1.26–1.73; pooled OR = 1.53, 95% CI = 1.26–1.81, for G/T vs T/T; pooled OR = 2.04, 95% CI = 1.54–2.71 for G/G vs T/T]. For p53 Arg72Pro, a total of 21 studies with 7285 cases and 9710 controls suggested that the variant was also associated with HCC risk under common genetic model (allele Pro vs Arg, pooled OR = 1.13, 95% CI = 1.02–1.25; Pro/Pro vs Arg/Arg, pooled OR = 1.32, 95% CI =1.06–1.64). …”
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177por Pandey, Saurabh Prakash, Singh, Amar Pal, Srivastava, Shruti, Chandrashekar, Krishnappa, Sane, Aniruddha P.“…The expression of insecticidal proteins under constitutive promoters in transgenic plants is fraught with problems like developmental abnormalities, yield drag, expression in unwanted tissues, and seasonal changes in expression. RbPCD1pro, a rapid, early acting wound‐inducible promoter from rose that is activated within 5 min of wounding, was isolated and characterized. …”
Publicado 2019
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178por Bachour, Yara, Poort, Linda, Verweij, Stephan P., van Selms, Gijs, Winters, Hay A. H., Ritt, Marco J. P. F., Niessen, Frank B., Budding, Andries E.“…All specimens were analysed by IS-pro, a 16S–23S interspace region-based PCR assay. …”
Publicado 2019
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179por Redweik, Graham A. J., Daniels, Karrie, Severin, Andrew J., Lyte, Mark, Mellata, Melha“…White Leghorn chicks were either non-treated (CON) or orally given probiotics (PRO), a recombinant attenuated Salmonella vaccine (RASV; VAX), or both (P+V). …”
Publicado 2020
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180por Konno, Sho, Thanigaimalai, Pillaiyar, Yamamoto, Takehito, Nakada, Kiyohiko, Kakiuchi, Rie, Takayama, Kentaro, Yamazaki, Yuri, Yakushiji, Fumika, Akaji, Kenichi, Kiso, Yoshiaki, Kawasaki, Yuko, Chen, Shen-En, Freire, Ernesto, Hayashi, Yoshio“…We describe here the design, synthesis and biological evaluation of a series of molecules toward the development of novel peptidomimetic inhibitors of SARS-CoV 3CL(pro). A docking study involving binding between the initial lead compound 1 and the SARS-CoV 3CL(pro) motivated the replacement of a thiazole with a benzothiazole unit as a warhead moiety at the P1′ site. …”
Publicado 2013
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