Mostrando 461 - 480 Resultados de 1,808 Para Buscar '"Pro B"', tiempo de consulta: 0.24s Limitar resultados
  1. 461
    “…The relevance of B-type NP (BNP) and N-terminal pro-B-type NP (NT-proBNP) for diagnosis and risk stratification has been extensively demonstrated, and these biomarkers are emerging tools for population screening and as guides to the start of treatment in subclinical HF. …”
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    Biomarkers of HFpEF: Natriuretic Peptides, High-Sensitivity Troponins and Beyond
  2. 462
    “…Tachycardia and atrial fibrillation were identified, with elevated D-dimer, N-terminal pro-B-type natriuretic peptide, creatine kinase, and C-reactive protein levels. …”
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    Evaluation of coronavirus-2019-related arterial thrombosis in noncontrast spectral computed tomography with electron density imaging
  3. 463
    por Nagel, Stefan
    Publicado 2023
    “…Classification of TALE homeobox gene expression patterns for the hematopoietic compartment, termed TALE-code, has revealed exclusive IRX1 activity in pro-B-cells and megakaryocyte erythroid progenitors (MEPs), highlighting its specific contribution to developmental processes at these early stages of hematopoietic lineage differentiation. …”
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    The Role of IRX Homeobox Genes in Hematopoietic Progenitors and Leukemia
  4. 464
    “…Compared with non‐selected outpatients, inpatients were older (71 ± 12 vs. 68 ± 12 years, P = 0.02), had more frequent Functional Class III–IV (58 [58.0%] vs. 129 [30.3%], P < 0.001), had higher levels of N‐terminal pro‐B type natriuretic peptide (4044 [1630–8680] vs. 2182 [1134–4172]; P < 0.001), and were receiving angiotensin‐converting enzyme inhibitors/angiotensin receptor blockers target dose less frequently (55 [55.0%] vs. 335 [78.5%]; P < 0.001). …”
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    Safety of sacubitril/valsartan initiated during hospitalization: data from a non‐selected cohort
  5. 465
    “…DESIGN, SETTING, AND PARTICIPANTS: This intention-to-treat feasibility trial randomized patients with acute myocardial infarction undergoing early revascularization and with N-terminal–pro-B-type natriuretic peptide concentration more than 300 pg/mL to RIM or SC across 3 hospitals in Singapore from July 8, 2015, to March 29, 2019. …”
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    Remote Postdischarge Treatment of Patients With Acute Myocardial Infarction by Allied Health Care Practitioners vs Standard Care: The IMMACULATE Randomized Clinical Trial
  6. 466
    “…Empagliflozin reduced LV end-diastolic volume index by 8.2 (95% CI, –13.7 to –2.6) mL/m(2) (P=0.0042) and reduced N-terminal pro-B-type natriuretic peptide by 28% (2%–47%), P=0.038. …”
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    Effect of Empagliflozin on Left Ventricular Volumes in Patients With Type 2 Diabetes, or Prediabetes, and Heart Failure With Reduced Ejection Fraction (SUGAR-DM-HF)
  7. 467
    “…Elevated levels of myoglobin, troponin, creatine kinase-MB, plasma interleukin-6, lactate dehydrogenase (LDH), and N-terminal pro-b-type natriuretic peptide (NT-proBNP) have been found in COVID-19-associated myocardial injuries. …”
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    COVID-19 and Cardiovascular Diseases: A Literature Review From Pathogenesis to Diagnosis
  8. 468
    “…For prognostic purposes, it is necessary to monitor sRV size and function, the tricuspid valve regurgitation, the functional class, the occurrence of syncope, the QRS duration, N-terminal pro B-type natriuretic peptide levels, and the development of arrhythmias. …”
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    Overview of Long-Term Outcome in Adults with Systemic Right Ventricle and Transposition of the Great Arteries: A Review
  9. 469
    “…The review covers the clinical applications of novel biomarkers, such as high-sensitivity troponin, galectin-3, source of tumorigenicity 2, B-type natriuretic peptide and N-terminal pro-B-type natriuretic peptide, growth differentiation factor 15, myeloperoxidase, fatty acid-binding protein, C-reactive protein, lipoprotein-associated phospholipase A2, microRNAs, circulating endothelial cells, and ischemia-modified albumin. …”
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    Novel Biomarkers and the Multiple-Marker Approach in Early Detection, Prognosis, and Risk Stratification of Cardiac Diseases: A Narrative Review
  10. 470
    “…Deletion of CRD1 and CRD2 arrested B cell development at an uncommitted pro-B cell stage. Most Pax5-regulated genes required CRD1 or both CRD1 and CRD2 for their activation or repression as these domains induced or eliminated open chromatin at Pax5-activated or Pax5-repressed genes, respectively. …”
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    Essential role of the Pax5 C-terminal domain in controlling B cell commitment and development
  11. 471
    “…This process involves several sequential, complex events, starting with pre- and pro-B cells, which rearrange the heavy and light chain genes responsible for producing clonally diverse immunoglobulin (Ig) molecules. …”
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    Isolation and Analysis of B-cell Progenitors from Bone Marrow by Flow Cytometry
  12. 472
    “…At diagnosis, N−terminal pro−B−type natriuretic peptide (NT−pro−BNP) levels were significantly higher, but the time−course of NT−pro−BNP levels during treatment was significantly more favorable in individuals with pulmonary arterial hypertension (PH Group 1) who did versus did not have hypocapnia (p = 0.026 and p = 0.017, respectively). …”
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    Significance of Hypocapnia in the Risk Assessment of Patients with Pulmonary Hypertension
  13. 473
    “…This replacement, denoted EμR, substantially increases the accessibility of both V(κ) and J(κ) loci to V(D)J recombinase in pro–B cells and induces Igk rearrangement in these cells. …”
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    Critical roles of the immunoglobulin intronic enhancers in maintaining the sequential rearrangement of IgH and Igk loci
  14. 474
    “…The essential role of Igβ for human B cell development was further demonstrated by immunofluorescence analysis of the patient's bone marrow, which showed a complete block of B cell development at the pro-B to preB transition. These results indicate that mutations in Igβ can cause agammaglobulinemia in man.…”
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    Mutations of the Igβ gene cause agammaglobulinemia in man
  15. 475
    Publicado 1995
    “…In mice bearing targeted disruptions of either the RAG-1 or RAG-2 genes, T and B lymphocyte development is arrested at the CD4-8- double negative (DN) thymocyte or B220+/CD43+ pro-B cell stage. Development of CD4+CD8+ double positive (DP) thymocytes is restored by expression of a functionally rearranged TCR beta transgene, suggesting that TCR beta expression is critical for this developmental transition. …”
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    Development of CD4+CD8+ thymocytes in RAG-deficient mice through a T cell receptor beta chain-independent pathway
  16. 476
    “…Whereas DH–JH rearrangement is normally initiated and completed at the pro-B cell stage, in μ-tg mice it continues beyond this stage and occurs most frequently at the small (late) pre-B stage. …”
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    Extended Duration of DH–JH Rearrangement in Immunoglobulin Heavy Chain Transgenic Mice: Implications for Regulation of Allelic Exclusion
  17. 477
    “…Conversely, the bone marrow (BM) had reduced immature B cell numbers, but normal numbers of pro-B cells. vcam-1–deficient mice also had reduced mature IgD(+) B and T cells in BM and a greatly reduced capacity to support short-term migration of transferred B cells, CD4(+) T cells, CD8(+) T cells, and preactivated CD4(+) T cells to the BM. …”
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    Conditional Vascular Cell Adhesion Molecule 1 Deletion in Mice: Impaired Lymphocyte Migration to Bone Marrow
  18. 478
    “…Strikingly, when the Igα ITAM mutation was combined with a truncation of Igβ, B cell development was completely blocked at the pro-B cell stage, indicating a crucial role of ITAM phosphorylation in B cell development.…”
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    Interference with Immunoglobulin (Ig)α Immunoreceptor Tyrosine–Based Activation Motif (Itam) Phosphorylation Modulates or Blocks B Cell Development, Depending on the Availability of an Igβ Cytoplasmic Tail
  19. 479
    por Lin, Qun, Dong, Chen, Cooper, Max D.
    Publicado 1998
    “…The bone marrow progenitor population of CD43(+)B220(+)HSA(−) cells was unaffected, but development of the CD19(+) pro–B cells and their B lineage progeny was severely impaired. …”
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    Impairment of  T and B Cell Development by Treatment with a Type I Interferon
  20. 480
    “…Other investigators found that higher N-terminal pro B-type natriuretic peptide (NT-proBNP) levels may be useful markers for post-traumatic cardiac impairment. …”
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    Year in review 2008: Critical Care - trauma
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