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1521por Lindmark, Krister, Boman, Kurt, Olofsson, Mona, Törnblom, Michael, Levine, Aaron, Castelo-Branco, Anna, Schlienger, Raymond, Bruce Wirta, Sara, Stålhammar, Jan, Wikström, Gerhard“…While 83.5% of patients underwent N-terminal pro-B-type natriuretic peptide testing, only 36.4% of patients had an echocardiogram at the time of diagnosis, although this increased overtime. …”
Publicado 2019
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1522por Kuh, Diana, Cooper, Rachel, Sattar, Naveed, Welsh, Paul, Hardy, Rebecca, Ben-Shlomo, Yoav“…We tested associations between logged and standardized measures of cystatin C, NT-proBNP (N-terminal pro-B-type natriuretic peptide), interleukin (IL)-6, and E-selectin at age 60 to 64 years with performance at age 69 years, adjusting for sex, height, and body mass index; then for performance at age 60 to 64 years. …”
Publicado 2019
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1523por Hijazi, Ziad, Verdecchia, Paolo, Oldgren, Jonas, Andersson, Ulrika, Reboldi, Gianpaolo, Di Pasquale, Giuseppe, Mazzotta, Giovanni, Angeli, Fabio, Eikelboom, John W., Ezekowitz, Michael D., Connolly, Stuart J., Yusuf, Salim, Wallentin, Lars“…NT‐proBNP (N‐terminal pro‐B‐type natriuretic peptide), cardiac troponin I and T, and growth differentiation factor‐15 were determined using high‐sensitivity (hs) assays. …”
Publicado 2019
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1524por Zelniker, Thomas A., Jarolim, Petr, Scirica, Benjamin M., Braunwald, Eugene, Park, Jeong‐Gun, Das, Saumya, Sabatine, Marc S., Morrow, David A.“…METHODS AND RESULTS: We measured baseline serum beta‐CTx, NT‐proBNP (N‐terminal pro‐B‐type natriuretic peptide), hsTnT (high‐sensitivity cardiac troponin T) and hsCRP (high‐sensitivity C‐reactive protein) (Roche Diagnostics) in a nested biomarker analysis (n=4094) from a study of patients with non–ST‐elevation acute coronary syndrome. …”
Publicado 2019
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1525por Özlek, Bülent, Özlek, Eda, Kahraman, Serkan, Tekinalp, Mehmet, Ağuş, Hicaz Zencirkıran, Çelik, Oğuzhan, Çil, Cem, Doğan, Volkan, Başaran, Özcan, Kaya, Bedri Caner, Rencüzoğulları, İbrahim, Ösken, Altuğ, Bekar, Lütfü, Çakır, Mustafa Ozan, Çelik, Yunus, Mert, Kadir Uğur, Sancar, Kadriye Memiç, Sevinç, Samet, Mert, Gurbet Özge, Biteker, Murat“…Women had higher N-terminal pro-B-type natriuretic peptide (691 pg/mL vs. 541 pg/mL, p=0.004), lower hemoglobin (12.7 g/dL vs. 13.8 g/dL, p<0.001), and serum ferritin (51 ng/mL vs. 64 ng/mL, p=0.001) levels, and they had worse diastolic function (E/e’=10 vs. 9, p<0.001). …”
Publicado 2019
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1526por Geenen, Laurie W, Baggen, Vivan J M, van den Bosch, Annemien E, Eindhoven, Jannet A, Cuypers, Judith A A E, Witsenburg, Maarten, Boersma, Eric, Roos-Hesselink, Jolien W“…After a median follow-up of 5.8 [IQR 5.1–6.2) years, 225 (38.5%) reached the primary endpoint. sST2 was significantly associated with the primary endpoint when adjusted for age, sex, creatinine and N terminal pro-B type brain natriuretic peptide (NT-proBNP) (HR per twofold higher sST2: 1.28, 95% CI 1.03 to 1.58, p=0.025). …”
Publicado 2019
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1527por Vanhaverbeke, Maarten, Vausort, Mélanie, Veltman, Denise, Zhang, Lu, Wu, Ming, Laenen, Griet, Gillijns, Hilde, Moreau, Yves, Bartunek, Jozef, Van De Werf, Frans, Devaux, Yvan, Janssens, Stefan, Sinnaeve, Peter R.“…QSOX1 had an incremental predictive value in a model consisting of clinical variables and cardiac biomarkers (including NT-proBNP [N-terminal pro-B-type natriuretic peptide]). In the porcine MI model, whole-blood levels of QSOX1 and PLBD1 related to neutrophil infiltration in the ischemic myocardium in an infarct size–independent manner. …”
Publicado 2019
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1528por Nordin, Sabrina, Kozor, Rebecca, Vijapurapu, Ravi, Augusto, João B., Knott, Kristopher D., Captur, Gabriella, Treibel, Thomas A., Ramaswami, Uma, Tchan, Michel, Geberhiwot, Tarekegn, Steeds, Richard P., Hughes, Derralynn A., Moon, James C.“…Cardiovascular magnetic resonance (left ventricular mass index, T1, T2, global longitudinal strain, and late gadolinium enhancement) and biomarkers (high-sensitive troponin-T and NT-proBNP [N-terminal Pro-B-type natriuretic peptide]) at baseline (pre-ERT) and 12 months were performed. …”
Publicado 2019
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1529por Núñez, Julio, Miñana, Gema, Cardells, Ingrid, Palau, Patricia, Llàcer, Pau, Fácila, Lorenzo, Almenar, Luis, López‐Lereu, Maria P., Monmeneu, Jose V., Amiguet, Martina, González, Jessika, Serrano, Alicia, Montagud, Vicente, López‐Vilella, Raquel, Valero, Ernesto, García‐Blas, Sergio, Bodí, Vicent, de la Espriella‐Juan, Rafael, Lupón, Josep, Navarro, Jorge, Górriz, José Luis, Sanchis, Juan, Chorro, Francisco J., Comín‐Colet, Josep, Bayés‐Genís, Antoni“…Median age was 73 (65–78) years, with N‐terminal pro‐B‐type natriuretic peptide, ferritin, and transferrin saturation medians of 1690 pg/mL (1010–2828), 63 ng/mL (22–114), and 15.7% (11.0–19.2), respectively. …”
Publicado 2020
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1530por Yang, Shengwen, Liu, Zhimin, Hu, Yiran, Jing, Ran, Gu, Min, Niu, Hongxia, Ding, Ligang, Xing, Anlu, Zhang, Shu, Hua, Wei“…RESULTS: In a multivariate analysis, the predictors of all-cause death were left atrial diameter [Hazard ratio (HR): 1.056, 95% confidence interval (CI): 1.020–1.093, P = 0.002]; non-left bundle branch block [HR: 1.793, 95% CI: 1.131–2.844, P = 0.013]; high sensitivity C-reactive protein [HR: 1.081, 95% CI: 1.029–1.134 P = 0.002]; and N-terminal pro-B-type natriuretic peptide [HR: 1.018, 95% CI: 1.007–1.030, P = 0.002]; and New York Heart Association class IV [HR: 1.018, 95% CI: 1.007–1.030, P = 0.002]. …”
Publicado 2020
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1531por Hinrichs, Lena, Mrotzek, Simone Maria, Mincu, Raluca-Ileana, Pohl, Julia, Röll, Alina, Michel, Lars, Mahabadi, Amir Abbas, Al-Rashid, Fadi, Totzeck, Matthias, Rassaf, Tienush“…METHODS: This retrospective study was performed to evaluate the diagnostic value of cardiac troponin I (cTnI) and N-terminal pro-B-type natriuretic peptide (NT-proBNP) for monitoring cancer therapy-induced cardiomyopathy. …”
Publicado 2020
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1532por Kaushik, Shubhi, Aydin, Scott I., Derespina, Kim R., Bansal, Prerna B., Kowalsky, Shanna, Trachtman, Rebecca, Gillen, Jennifer K., Perez, Michelle M., Soshnick, Sara H., Conway, Edward E., Bercow, Asher, Seiden, Howard S., Pass, Robert H., Ushay, Henry M., Ofori-Amanfo, George, Medar, Shivanand S.“…C-reactive protein, procalcitonin, d-dimer, and pro-B-type natriuretic peptide levels were elevated in all patients. …”
Publicado 2020
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1533por Karhu, S. Tuuli, Kinnunen, Sini M., Tölli, Marja, Välimäki, Mika J., Szabó, Zoltán, Talman, Virpi, Ruskoaho, Heikki“…Interestingly, the compound 3i-1000 attenuated doxorubicin-induced increase in pro-B-type natriuretic peptide (proBNP) expression and caspase-3/7 activation in hiPSC-CMs. …”
Publicado 2020
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1534por Vaes, Bert, Indestege, Paulien, Serneels, Tinne, Hegendörfer, Eralda, van Peet, Petra G, Poortvliet, Rosalinde K E, Wallemacq, Pierre, Gussekloo, Jacobijn, Degryse, Jan“…In participants without a history of CVD, adding N-terminal pro-B-type natriuretic peptide (NT-pro-BNP) improved the prediction (NRI 0.56 (95% CI 0.16 to 0.99) and relative IDI 4.01 (95% CI 2.19 to 6.28)). …”
Publicado 2020
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1535por van den Heuvel, F. M. A., Vos, J. L., Koop, Y., van Dijk, A. P. J., Duijnhouwer, A. L., de Mast, Q., van de Veerdonk, F. L., Bosch, F., Kok, B., Netea, M. G., Hoogerwerf, J., Hoefsloot, W., Tjwa, E. T. T. L., de Korte, C. L., van Kimmenade, R. R. J., Nijveldt, R.“…Laboratory assessment included high-sensitivity Troponin T and N‑terminal pro-B-type natriuretic peptide (NT-proBNP). Echocardiographic evaluation focused on left and right ventricular systolic function and global longitudinal strain (GLS). …”
Publicado 2020
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1536por Garg, Pankaj, Wood, Steven, Swift, Andrew J., Fent, Graham, Lewis, Nigel, Rogers, Dominic, Rothman, Alexander, Charalampopoulos, Athanasios, Al‐Mohammad, Abdallah“…The aim of this study was to investigate the clinical predictors of all‐cause mortality in patients with suspected HF, a raised N‐terminal pro‐b‐type natriuretic peptide (NTproBNP) and who do not meet the diagnostic criteria of any type of HF by echocardiography. …”
Publicado 2020
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1537por Qin, Juan-Juan, Cheng, Xu, Zhou, Feng, Lei, Fang, Akolkar, Gauri, Cai, Jingjing, Zhang, Xiao-Jing, Blet, Alice, Xie, Jing, Zhang, Peng, Liu, Ye-Mao, Huang, Zizhen, Zhao, Ling-Ping, Lin, Lijin, Xia, Meng, Chen, Ming-Ming, Song, Xiaohui, Bai, Liangjie, Chen, Ze, Zhang, Xingyuan, Xiang, Da, Chen, Jing, Xu, Qingbo, Ma, Xinliang, Touyz, Rhian M., Gao, Chen, Wang, Haitao, Liu, Liming, Mao, Weiming, Luo, Pengcheng, Yan, Youqin, Ye, Ping, Chen, Manhua, Chen, Guohua, Zhu, Lihua, She, Zhi-Gang, Huang, Xiaodong, Yuan, Yufeng, Zhang, Bing-Hong, Wang, Yibin, Liu, Peter P., Li, Hongliang“…In the mixed-effects Cox model, after adjusting for age, sex, and comorbidities, the adjusted hazard ratio of 28-day mortality for hs-cTnI (high-sensitivity cardiac troponin I) was 7.12 ([95% CI, 4.60–11.03] P<0.001), (NT-pro)BNP (N-terminal pro-B-type natriuretic peptide or brain natriuretic peptide) was 5.11 ([95% CI, 3.50–7.47] P<0.001), CK (creatine phosphokinase)-MB was 4.86 ([95% CI, 3.33–7.09] P<0.001), MYO (myoglobin) was 4.50 ([95% CI, 3.18–6.36] P<0.001), and CK was 3.56 ([95% CI, 2.53–5.02] P<0.001). …”
Publicado 2020
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1538“…PATIENTS AND METHODS: We measured plasma ghrelin and pro B-type natriuretic peptide (NT-proBNP) levels upon emergency admission in 241 prospectively recruited elderly AHF patients (61.0% men). …”
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1539por Ueland, Thor, Heggelund, Lars, Lind, Andreas, Holten, Aleksander R., Tonby, Kristian, Michelsen, Annika E., Jenum, Synne, Jørgensen, Marthe J., Barratt-Due, Andreas, Skeie, Linda G., Nordøy, Ingvild, Aanensen Fraz, Mai Sasaki, Quist-Paulsen E, Else, Pischke, Søren E., Johal, Simreen K., Hesstvedt, Liv, Bogen, Mette, Fevang, Børre, Halvorsen, Bente, Müller, Fredrik, Bekken, Gry Kloumann, Mollnes, Tom E., Dudman, Susanne, Aukrust, Pål, Dyrhol-Riise, Anne M., Holter, Jan C.“…RESULTS: Our major findings were as follows: (1) severe clinical outcome (ICU treatment) was associated with high plasma levels of sTIM-3 and myeloperoxidase, suggesting activated and potentially exhausted T cells and activated neutrophils, respectively; (2) in contrast, sCD14 and sCD163 showed no association with need for ICU treatment; and (3) levels of sCD25, sTIM-3, and myeloperoxidase were inversely correlated with degree of respiratory failure, as assessed by the ratio of Pao(2) to fraction of inspired oxygen, and were positively correlated with the cardiac marker N-terminal pro-B–type natriuretic peptide. CONCLUSION: Our findings suggest that neutrophil activation and, in particular, activated T cells may play an important role in the pathogenesis of COVID-19 infection, suggesting that T-cell–targeted treatment options and downregulation of neutrophil activation could be of importance in this disorder.…”
Publicado 2021
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1540por Su, Yang, Ma, Mengqiu, Zhang, Hengbin, Pan, Xin, Zhang, Xianling, Zhang, Fenglei, Lv, Yangbo, Yan, Chunxi“…The hyponatremia group had lower blood pressure and serum hemoglobin, higher N-terminal pro B-type natriuretic peptide (NT-proBNP) and D-dimer, more patients with a history of atrial fibrillation and a higher proportion of spironolactone and loop diuretic use. …”
Publicado 2020
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