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1741por Nemec Svete, Alenka, Verk, Barbara, Čebulj-Kadunc, Nina, Salobir, Janez, Rezar, Vida, Domanjko Petrič, Aleksandra“…Associations between the disease severity marker N-terminal pro-B-type natriuretic peptide (NT-proBNP) and markers of inflammation and oxidative stress were also determined. …”
Publicado 2021
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1742por van den Bosch, Eva, Bossers, Sjoerd S. M., Kamphuis, Vivian P., Boersma, Eric, Roos‐Hesselink, Jolien W., Breur, Johannes M. P. J., Ten Harkel, Arend D. J., Kapusta, Livia, Bartelds, Beatrijs, Roest, Arno A. W., Kuipers, Irene M., Blom, Nico A., Koopman, Laurens P., Helbing, Willem A.“…Several biomarkers including NT‐proBNP (N‐terminal pro‐B‐type natriuretic peptide), GDF‐15 (growth differentiation factor 15), Gal‐3 (galectin‐3), ST2 (suppression of tumorigenicity 2), DLK‐1 (protein delta homolog 1), FABP‐4 (fatty acid‐binding protein 4), IGFBP‐1 (insulin‐like growth factor‐binding protein 1), IGFBP‐7, MMP‐2 (matrix metalloproteinase 2), and vWF (von Willebrand factor) were assessed in blood at 9.6 (7.1–12.1) years after Fontan completion. …”
Publicado 2021
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1743por Seoudy, Hatim, Al‐Kassou, Baravan, Shamekhi, Jasmin, Sugiura, Atsushi, Frank, Johanne, Saad, Mohammed, Bramlage, Peter, Seoudy, Anna Katharina, Puehler, Thomas, Lutter, Georg, Schulte, Dominik M., Laudes, Matthias, Nickenig, Georg, Frey, Norbert, Sinning, Jan‐Malte, Frank, Derk“…Other independent risk factors included albumin level < median of 4.0 g/dL, high‐sensitive troponin T in the highest quartile (> 45.0 pg/mL), N‐terminal pro‐B‐type natriuretic peptide in the highest quartile (> 3595 pg/mL), grade III–IV tricuspid regurgitation, pulmonary arterial hypertension, life‐threatening bleeding, AKIN Stage 3 and disabling stroke. …”
Publicado 2021
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1744por Marcks, Nick, Aimo, Alberto, Januzzi, James L., Vergaro, Giuseppe, Clerico, Aldo, Latini, Roberto, Meessen, Jennifer, Anand, Inder S., Cohn, Jay N., Gravning, Jørgen, Ueland, Thor, Bayes-Genis, Antoni, Lupón, Josep, de Boer, Rudolf A., Yoshihisa, Akiomi, Takeishi, Yasuchika, Egstrup, Michael, Gustafsson, Ida, Gaggin, Hanna K., Eggers, Kai M., Huber, Kurt, Tentzeris, Ioannis, Ripoli, Andrea, Passino, Claudio, Sanders-van Wijk, Sandra, Emdin, Michele, Brunner-La Rocca, Hans-Peter“…After including medications and N-terminal pro-B-type natriuretic peptide and high-sensitivity cardiac troponin concentrations into the model, the prognostic impact of BMI was largely absent even in the elderly group with co-morbidity. …”
Publicado 2021
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1745por Meng, Jian-Biao, Hu, Ma-Hong, Zhang, Ming, Hu, Gong-Pai, Zhang, Wei, Hu, Shen-Jiang“…Both increased whole blood Cu and Cu/Zn ratio and reduced Zn were associated with lower LVEF (all p<0.001) and higher amino-terminal pro-B-type natriuretic peptide (NT-proBNP) (Cu, p=0.002; Zn, p<0.001; Cu/Zn ratio, p<0.001) and had predictive values for SILVSD (Cu, AUC=0.666, p=0.005; Zn, AUC=0.625, p=0.039; Cu/Zn ratio, AUC=0.674, p=0.029). …”
Publicado 2021
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1746por Yap, Jin Yan, Moens, Leen, Lin, Ming-Wei, Kane, Alisa, Kelleher, Anthony, Toong, Catherine, Wu, Kathy H.C., Sewell, William A., Phan, Tri Giang, Hollway, Georgina E., Enthoven, Karen, Gray, Paul E., Casas-Martin, Jose, Wouters, Carine, De Somer, Lien, Hershfield, Michael, Bucciol, Giorgia, Delafontaine, Selket, Ma, Cindy S., Tangye, Stuart G., Meyts, Isabelle“…We confirmed a defect in terminal B cell differentiation in DADA2 and reveal a block in B cell development in the bone marrow at the pro-B to pre-B cell stage. We also show impaired differentiation of CD4(+) and CD8(+) memory T cells, accelerated exhaustion/senescence, and impaired survival and granzyme production by ADA2 deficient CD8(+) T cells. …”
Publicado 2021
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1747por Petersen, Elina Larissa, Goßling, Alina, Adam, Gerhard, Aepfelbacher, Martin, Behrendt, Christian-Alexander, Cavus, Ersin, Cheng, Bastian, Fischer, Nicole, Gallinat, Jürgen, Kühn, Simone, Gerloff, Christian, Koch-Gromus, Uwe, Härter, Martin, Hanning, Uta, Huber, Tobias B., Kluge, Stefan, Knobloch, Johannes K., Kuta, Piotr, Schmidt-Lauber, Christian, Lütgehetmann, Marc, Magnussen, Christina, Mayer, Carola, Muellerleile, Kai, Münch, Julia, Nägele, Felix Leonard, Petersen, Marvin, Renné, Thomas, Riedl, Katharina Alina, Rimmele, David Leander, Schäfer, Ines, Schulz, Holger, Tahir, Enver, Waschki, Benjamin, Wenzel, Jan-Per, Zeller, Tanja, Ziegler, Andreas, Thomalla, Götz, Twerenbold, Raphael, Blankenberg, Stefan“…Cardiac assessment revealed slightly lower measures of left (regression coefficient for left ventricular ejection fraction on transthoracic echocardiography −0.93, adjusted P = 0.015) and right ventricular function and higher concentrations of cardiac biomarkers (factor 1.14 for high-sensitivity troponin, 1.41 for N-terminal pro-B-type natriuretic peptide, adjusted P ≤ 0.01) in post-SARS-CoV-2 patients compared with matched controls, but no significant differences in cardiac magnetic resonance imaging findings. …”
Publicado 2022
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1748Cardiac dysfunction in Multisystem Inflammatory Syndrome in Children: An Italian single-center studypor Mannarino, Savina, Raso, Irene, Garbin, Massimo, Ghidoni, Elena, Corti, Carla, Goletto, Sara, Nespoli, Luisa, Santacesaria, Sara, Zoia, Elena, Camporesi, Anna, Izzo, Francesca, Dilillo, Dario, Fiori, Laura, D’Auria, Enza, Silvestri, Annalisa De, Dolci, Alberto, Calcaterra, Valeria, Zuccotti, Gianvincenzo“…Significant differences were noted among clinical presentations (shock, diarrhea, intensive care unit admission), laboratory markers (leucocytes, neutrophils, and protein C-reactive), and cardiac markers (troponin T and N-terminal pro B-type Natriuretic Peptide) between the groups, with higher compromission in Group A. …”
Publicado 2022
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1749por Mazza, Alberto, Townsend, Danyelle M., Torin, Gioia, Schiavon, Laura, Camerotto, Alessandro, Rigatelli, Gianluca, Cuppini, Stefano, Minuz, Pietro, Rubello, Domenico“…The clinic blood pressure (BP), N-terminal pro-B-type natriuretic peptide (NT-proBNP), estimated glomerular filtration rate (eGFR), blood glucose and glycated hemoglobin (HbA1c), uric acid (UA), left ventricular ejection fraction (LVEF) and NYHA class were evaluated at a mean follow-up of 12 months. …”
Publicado 2020
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1750por Hamatani, Yasuhiro, Iguchi, Moritake, Ikeyama, Yurika, Kunugida, Atsuko, Ogawa, Megumi, Yasuda, Natsushige, Fujimoto, Kana, Ichihara, Hidenori, Sakai, Misaki, Kinoshita, Tae, Nakashima, Yasuyo, Akao, Masaharu“…Of 294 patients (mean age: 77.5 ± 12.0 years, male: 168 patients, New York Heart Association class IV: 96 patients, mean left ventricular ejection fraction [LVEF]: 44%, and median N‐terminal pro B‐type natriuretic peptide [NT‐proBNP] level: 4418 ng/L), the median (IQR) total IPOS score on admission was 19 (12, 27) and they were widely distributed (minimum: 0 – maximum: 52). …”
Publicado 2022
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1751por McKechnie, Douglas G. J., Patel, Meera, Papacosta, A. Olia, Lennon, Lucy T., Ellins, Elizabeth A., Halcox, Julian P. J., Ramsay, Sheena E., Whincup, Peter H., Wannamethee, S. Goya“…Multinominal logistic regression was performed to examine the associations between frailty status (robust/pre-frail/frail) and, separately, C-reactive protein (CRP), interleukin-6 (IL-6), tissue plasminogen activator (tPA), D-dimer, von Willebrand factor (vWF), high-sensitivity cardiac troponin-T (hs-cTnT), N-terminal pro B-type natriuretic peptide (NT-proBNP) (all natural log-transformed), and, in men without CVD, carotid intima-media thickness (CIMT), carotid-femoral pulse wave velocity (cfPWV), carotid distensibility coefficient (DC), and ankle-brachial pressure index (ABPI), adjusted for age, renal function, BMI, social class, smoking, polypharmacy, cognition, multimorbidity and systolic blood pressure. …”
Publicado 2022
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1752por Vinck, T. A. M., Deneer, R., Verstappen, CCAG, Kok, WE, Salah, K., Scharnhorst, V., Otterspoor, LC“…DESIGN: Quantitative, prospective, single centre, cohort study. METHODS: N-Terminal pro–B-type natriuretic peptide (NT-proBNP) levels were measured on admission and discharge, and were used together with clinical and laboratory parameters to calculate the ELAN-HF score. …”
Publicado 2022
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1753por Vergaro, Giuseppe, Gentile, Francesco, Aimo, Alberto, Januzzi, James L., Richards, A. Mark, Lam, Carolyn S.P., de Boer, Rudolf A., Meems, Laura M.G., Latini, Roberto, Staszewsky, Lidia, Anand, Inder S., Cohn, Jay N., Ueland, Thor, Gullestad, Lars, Aukrust, Pål, Brunner‐La Rocca, Hans‐Peter, Bayes‐Genis, Antoni, Lupón, Josep, Yoshihisa, Akiomi, Takeishi, Yasuchika, Egstrup, Michael, Gustafsson, Ida, Gaggin, Hanna K., Eggers, Kai M., Huber, Kurt, Gamble, Greg D., Ling, Lieng H., Leong, Kui Toh Gerard, Yeo, Poh Shuah Daniel, Ong, Hean Yee, Jaufeerally, Fazlur, Ng, Tze P., Troughton, Richard, Doughty, Robert N., Devlin, Gerry, Lund, Mayanna, Giannoni, Alberto, Passino, Claudio, Emdin, Michele“…AIMS: To define plasma concentrations, determinants, and optimal prognostic cut‐offs of soluble suppression of tumorigenesis‐2 (sST2), high‐sensitivity cardiac troponin T (hs‐cTnT), and N‐terminal pro‐B‐type natriuretic peptide (NT‐proBNP) in women and men with chronic heart failure (HF). …”
Publicado 2022
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1754“…Logistic analysis showed that the death group had higher serum creatinine (127.32 ± 47.82 vs. 82.61 ± 27.80 μmol/L, respectively; P = 0.0238) and N-terminal pro-B-type natriuretic peptide (NT-proBNP) [8,654.00 pg/mL (6,197.00–11,949.00 pg/mL) vs. 4,268.96 pg/mL (1,800.00–7,894.00 pg/mL), respectively; P = 0.0134] levels than the survival group. …”
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1755por Costa, Fabiana Lourenço, Reis, Nayrana Soares do Carmo, Reis, Fabricio Moreira, de Oliveira, Rogério Carvalho, Zanati Bazan, Silméia Garcia, Canedo da Silva, Maryanne Zilli, Martin, Luis Cuadrado, Barretti, Pasqual“…The control group has a significant increase in the tumor necrosis factor alpha median concentration from baseline to six [11.9 (6.0–24.1) vs. 44.7 (9.4–70.6) pg/ml] and 9 months [11.9 (6.0–24.1) vs. 39.4 (27.9–62.6) pg/ml], and in the N-terminal fragment of pro-B-type natriuretic peptide median [239 (171.5–360.5) vs. 356 (219–1,555) pg/ml]. …”
Publicado 2022
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1756por Jackson, Alice M., Rørth, Rasmus, Liu, Jiankang, Kristensen, Søren Lund, Anand, Inder S., Claggett, Brian L., Cleland, John G.F., Chopra, Vijay K., Desai, Akshay S., Ge, Junbo, Gong, Jianjian, Lam, Carolyn S.P., Lefkowitz, Martin P., Maggioni, Aldo P., Martinez, Felipe, Packer, Milton, Pfeffer, Marc A., Pieske, Burkert, Redfield, Margaret M., Rizkala, Adel R., Rouleau, Jean L., Seferović, Petar M., Tromp, Jasper, Van Veldhuisen, Dirk J., Yilmaz, Mehmet B., Zannad, Faiez, Zile, Michael R., Køber, Lars, Petrie, Mark C., Jhund, Pardeep S., Solomon, Scott D., McMurray, John J.V.“…METHODS AND RESULTS: Patients aged ≥50 years with left ventricular ejection fraction ≥45%, structural heart disease and elevated N‐terminal pro‐B‐type natriuretic peptide (NT‐proBNP) were eligible. …”
Publicado 2022
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1757por Moysidis, Dimitrios V., Daios, Stylianos, Anastasiou, Vasileios, Liatsos, Alexandros C., Papazoglou, Andreas S., Karagiannidis, Efstratios, Kamperidis, Vasileios, Makedou, Kali, Thisiadou, Aikaterini, Karalazou, Paraskevi, Papadakis, Marios, Savopoulos, Christos, Ziakas, Antonios, Giannakoulas, George, Vassilikos, Vassilios, Giannopoulos, Georgios“…Complete demographic and comprehensive clinical data will be recorded, Venous blood samples will be collected before coronary angiography and the following parameters will be measured: total blood count, standard biochemistry parameters, coagulation tests, hormone levels, glycosylated hemoglobin, N- terminal pro-B-type natriuretic peptide and high-sensitivity troponin T levels- as well as serum levels of novel atherosclerosis indicators and pro-inflammatory biomarkers. …”
Publicado 2023
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1758por Li, Ziyi, Liu, Mengnan, Chen, Mingtai, Luo, Gang, Wu, Jiao, Mazhar, Maryam, Yang, Fang, Zheng, Yu, Wu, Hao, Wu, Qibiao, Yang, Sijin“…The clinical efficacy rate (CER), left ventricular ejection fraction (LVEF), left ventricular end-diastolic dimension (LVEDD), left ventricular end-systolic diameter (LVESD), brain natriuretic peptide (BNP), N-terminal pro-B type natriuretic peptide (NT-proBNP) and hypersensitive C-reactive protein (hs-CRP) were included as outcome indicators. …”
Publicado 2023
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1759por Zampino, Serena, Sheikh, Farooq H., Vaishnav, Joban, Judge, Daniel, Pan, Baohan, Daniel, Amrita, Brown, Emily, Ebenezer, Gigi, Polydefkis, Michael“…The neurologic (examination, EMG, and skin biopsy), cardiac (echo), and laboratory assessments (pro b-type natriuretic peptide [proBNP] and reversible neuropathy screens) are described. …”
Publicado 2023
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1760por Hundertmark, Moritz J., Adler, Amanda, Antoniades, Charalambos, Coleman, Ruth, Griffin, Julian L., Holman, Rury R., Lamlum, Hanan, Lee, Jisoo, Massey, Daniel, Miller, Jack J.J.J., Milton, Joanne E., Monga, Shveta, Mózes, Ferenc E., Nazeer, Areesha, Raman, Betty, Rider, Oliver, Rodgers, Christopher T., Valkovič, Ladislav, Wicks, Eleanor, Mahmod, Masliza, Neubauer, Stefan“…METHODS: EMPA-VISION (Assessment of Cardiac Energy Metabolism, Function and Physiology in Patients With Heart Failure Taking Empagliflozin) is a prospective, randomized, double-blind, placebo-controlled, mechanistic trial that enrolled 72 symptomatic patients with chronic HF with reduced ejection fraction (HFrEF; n=36; left ventricular ejection fraction ≤40%; New York Heart Association class ≥II; NT-proBNP [N-terminal pro-B-type natriuretic peptide] ≥125 pg/mL) and HF with preserved ejection fraction (HFpEF; n=36; left ventricular ejection fraction ≥50%; New York Heart Association class ≥II; NT-proBNP ≥125 pg/mL). …”
Publicado 2023
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