“…OBJECTIVE: This study aimed to validate the Korean version of a short screening tool for psychosis as the first stage in finding undiagnosed psychosis in the community. …”
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“…Although previous studies suggested a link between the level of proinflammatory cytokines and abnormalities in brain structure in patients with schizophrenia, there is no in-vivo study investigating whether microglial activation is also linked to morphological brain alterations previously reported in individuals with psychosis and psychosis risk. METHODS: In order to address the current gap in the literature, we investigated microglial activation and structural brain abnormalities in key brain regions affected in psychosis (i.e. hippocampus and dorsolateral prefrontal cortex) of a large group of participants (N = 90) including 35 individuals at clinical high risk (CHR) for psychosis, 27 first-episode psychosis (mostly antipsychotic naïve) patients, and 28 healthy volunteers. …”
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“…BACKGROUND: Infections have long been linked to psychosis and categorised within “secondary” psychoses. …”
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“…Psychosis has no fully described tissue pathology, as vet, but is still identified and assessed symptomatically. …”
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“…Biological traits that are predictive of the later development of psychosis have not yet been identified. The complex, multidetermined nature of schizophrenia and other psychoses makes it unlikely that any single biomarker will be both sensitive and specific enough to unambiguously identify individuals who will later become psychotic. …”
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“…Methamphetamine (METH) is a frequent drug of abuse in U.S. populations and commonly associated with psychosis. This may be a factor in frequent criminal justice referrals and lengthy treatment required by METH users. …”
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“…The indication for strategies of intervention differs from the early to the late prodromal stage, depending on proximity to psychosis. For psychotherapy versus pharmacotherapy, the first evidence of effectiveness has been provided. …”
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“…Cannabis is a known risk factor for schizophrenia, although the exact neurobiological process through which the effects on psychosis occur is not well-understood. In this review, we attempt to develop and discuss a possible pathway for the development of psychosis. …”
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“…In addition, studies suggest that psychosis and mental illness-related experiences can be extremely traumatic. …”
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“…It’s major metabolite (diethyldithiocarbamate) is an inhibitor of dopamine-betahydroxylase, an enzyme that catalyzes the metabolism of dopamine to norepinephrine resulting in psychosis. We recommend that disulfiram should be used at the lowest effective dose, possibly 250 mg daily and caution should be taken while prescribing disulfiram for patients with personal and familial antecedents of psychosis.…”
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“…To the best of our knowledge, psychosis from arachnoid cysts has not been reported in the recent literature. …”
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