“…Wakefulness electroencephalography showed a normal background and some bilateral spike-wave discharges that did not explain the psychosis features. A comparative genomic hybridization array (180 K, Agilent, Santa Clara, CA, USA) revealed an 867-kb 16p13.3 duplication, interpreted as a variant of unknown significance confirmed by a quantitative PCR that also showed its maternal inheritance. …”
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“…Four hundred twelve cases of first-episode psychosis patients were chosen for comparison with clinical data from paper-based patient files. …”
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“…These regions had altered morphological relationships primarily with frontal lobe regions, and their network-level alterations were associated with positive symptoms of psychosis. Nonpsychotic relatives showed lower nodal centrality metrics in the prefrontal cortex and subcortical regions, and higher nodal centrality metrics in the left cingulate cortex and left thalamus. …”
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“…BACKGROUND: Emotion dysregulation has emerged as a transdiagnostic factor that potentially exacerbates the risk of early-onset, maintenance, and relapse of psychosis. Mindfulness is described as the awareness that emerges from paying attention to the present moment without judgment. …”
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“…A small number of case studies had supported a causal relationship between heavy khat use and psychosis or psychotic symptoms. There have been suicidal attempts and homicidal acts in those who used excess and prolonged use of khat. …”
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“…Severe adverse events (SAEs) were recorded in 118 (25%) patients; mostly hearing impairments (70%) and psychosis (11%). Overall, 184 (39%) patients had ‘unfavourable’ treatment outcomes [125 (26%) were deaths, 39 (8%) were lost to follow-up, 4 (<1%) were failures and 16 (3%) not evaluated]. …”
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“…Having another severe mental health diagnosis (e.g., bipolar disorder, psychosis). 5. Unwilling to have legal guardian sign the informed consent or participate in this study. …”
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“…METHODS AND ANALYSIS: Structured Individualised inTervention And Recovery (SITAR) is a two-arm pragmatic randomised controlled trial, focusing on patients aged 18–60 years with a hospital stay of 12–120 months and a primary diagnosis of psychosis. It tests the effectiveness of structural and process reform with and without an individually tailored recovery plan on patient outcomes of disability (primary outcome WHO Disability Assessment Scale), symptom severity, social and occupational functioning and quality of life. …”
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“…BACKGROUND: The prevalence of childhood psychopathology fluctuates across the lifespan, yet studies often adopt linear growth curve models (LGM) of estimation that assumes constant linear growth and do not account for the comorbidity between internalizing and externalizing behaviors in predicting later psychosis. This study tests whether internalizing and externalizing behaviors in early childhood (4–9 years) and adolescence (11–16 years) are best modelled by a two-part parallel piecewise growth model (2-PGM) or a single LGM (4–16 years) and whether specific developmental periods better predict psychotic-like experiences (PLEs) in adulthood (18 years). …”
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“…METHODS: Patients who met DSM-V schizophrenia diagnostic criteria from Dokuz Eylül University School of Medicine, Schizophrenia and Psychosis Outpatient Clinic were included into the study. …”
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“…It is considered a genetic biological model for psychosis vulnerability: 25–28% of 22q11DS adults is affected by a psychotic disorder. …”
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“…GluN2A and GluN2B are the main cortical NMDAR subunits, but genetic models provided evidence that psychosis-like effects of NMDAR antagonists are mediated by GluN2C/GluN2D subunits. …”
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“…Interventions to reduce tobacco smoking in patients with psychosis may therefore improve life expectancy in this group.…”
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“…The aim of this retrospective study is to understand the clinical characteristics of the patients with psychotic disorders to whom any LAI was prescribed at discharge from hospital METHODS: We screened the files of 400 inpatients with psychosis spectrum disorders who were treated in inpatient units of Istanbul Faculty of Medicine, Department of Psychiatry between 01.01.2014-01.016.2019. …”
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“…RESULTS: The longest hospitalizations were significantly related to the diagnosis of “schizophrenia and other psychosis” (Pearson Chi(2)=17.24; p=0.045), the presence of moderate and severe aggressiveness (Pearson chi(2)=29; p=0.000), compulsory treatment (Pearson Chi(2)=8.05; p=0.005), parenteral or other route administration of psycho-pharmacotherapy (Pearson Chi(2)=12.91; p=0.007), poli-therapy (Pearson Chi(2)=6.40; p=0.041), complex psychiatric activities (Pearson Chi(2)=12.26; p=0.002) and rehabilitative programs (Pearson Chi(2)=37.05; p=0.000) during the hospitalization and at discharge (Pearson Chi(2)=29.89; p=0.000). …”
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“…The HR for psychiatric disorders, in females, was 0.39 (95%CI 0.18 to 0.82); in particular, the HR for psychosis was 0.15 (95% CI 0.05 to 0.51). The HR for acute respiratory diseases in females was 0.44 (95% CI 0.21 to 0.95). …”
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“…After admission, he further developed visual hallucinations, psychosis, and consciousness deterioration. Brain magnetic resonance imaging and infection and tumor surveillances were negative. 18F-fluorodeoxyglucose positron emission tomography of brain revealed frontal and occipital hypometabolism and anterior cingulate gyrus and mesial temporal hypermetabolism. …”
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“…The most common psychiatric co-morbidities registered among the cases during the first year before the diagnosis of sexual abuse were stress, suicide attempt, and psychosis. Neuroleptics, sleeping pills, antidepressants, and tranquilizers were more frequently dispensed in cases than in controls. …”
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“…Exposure to MMI was defined using recorded clinical events for: depression, anxiety, psychosis, eating disorder, personality disorder and alcohol and substance misuse disorders. …”
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“…BACKGROUND: Global 12-month psychosis prevalence is estimated at roughly 0.4%, although prevalence of antipsychotic use in the U.S. is estimated at roughly 1.7%. …”
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