Clinical outcomes of fractional flow reserve by computed tomographic angiography-guided diagnostic strategies vs. usual care in patients with suspected coronary artery disease: the...

por Douglas, Pamela S., Pontone, Gianluca, Hlatky, Mark A., Patel, Manesh R., Norgaard, Bjarne L., Byrne, Robert A., Curzen, Nick, Purcell, Ian, Gutberlet, Matthias, Rioufol, Gilles, Hink, Ulrich, Schuchlenz, Herwig Walter, Feuchtner, Gudrun, Gilard, Martine, Andreini, Daniele, Jensen, Jesper M., Hadamitzky, Martin, Chiswell, Karen, Cyr, Derek, Wilk, Alan, Wang, Furong, Rogers, Campbell, De Bruyne, Bernard
Publicado 2015

Genome to Phenome: Improving Animal Health, Production, and Well-Being – A New USDA Blueprint for Animal Genome Research 2018–2027

por Rexroad, Caird, Vallet, Jeffrey, Matukumalli, Lakshmi Kumar, Reecy, James, Bickhart, Derek, Blackburn, Harvey, Boggess, Mark, Cheng, Hans, Clutter, Archie, Cockett, Noelle, Ernst, Catherine, Fulton, Janet E., Liu, John, Lunney, Joan, Neibergs, Holly, Purcell, Catherine, Smith, Timothy P. L., Sonstegard, Tad, Taylor, Jerry, Telugu, Bhanu, Eenennaam, Alison Van, Tassell, Curtis P. Van, Wells, Kevin
Publicado 2019

Namodenoson in Advanced Hepatocellular Carcinoma and Child–Pugh B Cirrhosis: Randomized Placebo-Controlled Clinical Trial

por Stemmer, Salomon M., Manojlovic, Nebojsa S., Marinca, Mihai Vasile, Petrov, Petar, Cherciu, Nelly, Ganea, Doina, Ciuleanu, Tudor Eliade, Pusca, Ioana Adriana, Beg, Muhammad Shaalan, Purcell, William T., Croitoru, Adina-Emilia, Ilieva, Rumyana Nedyalkova, Natošević, Sladjana, Nita, Amedeia Lavinir, Kalev, Dimitar Nikolaev, Harpaz, Zivit, Farbstein, Motti, Silverman, Michael H., Bristol, David, Itzhak, Inbal, Fishman, Pnina
Publicado 2021

Impact of Radiation Dose on Postoperative Complications in Esophageal and Gastroesophageal Junction Cancers

por Kastelowitz, Noah, Marsh, Megan D., McCarter, Martin, Meguid, Robert A., Bhardwaj, Narine Wandrey, Mitchell, John D., Weyant, Michael J., Scott, Christopher, Schefter, Tracey, Stumpf, Priscilla, Leong, Stephen, Messersmith, Wells, Lieu, Christopher, Leal, Alexis D., Davis, S. Lindsey, Purcell, William T., Kane, Madeleine, Wani, Sachin, Shah, Raj, Hammad, Hazem, Edmundowicz, Steven, Goodman, Karyn A.
Publicado 2021

Longitudinal dynamics of clonal hematopoiesis identifies gene-specific fitness effects

por Robertson, Neil A., Latorre-Crespo, Eric, Terradas-Terradas, Maria, Lemos-Portela, Jorge, Purcell, Alison C., Livesey, Benjamin J., Hillary, Robert F., Murphy, Lee, Fawkes, Angie, MacGillivray, Louise, Copland, Mhairi, Marioni, Riccardo E., Marsh, Joseph A., Harris, Sarah E., Cox, Simon R., Deary, Ian J., Schumacher, Linus J., Kirschner, Kristina, Chandra, Tamir
Publicado 2022

The Genetic Structure of the Swedish Population

por Humphreys, Keith, Grankvist, Alexander, Leu, Monica, Hall, Per, Liu, Jianjun, Ripatti, Samuli, Rehnström, Karola, Groop, Leif, Klareskog, Lars, Ding, Bo, Grönberg, Henrik, Xu, Jianfeng, Pedersen, Nancy L., Lichtenstein, Paul, Mattingsdal, Morten, Andreassen, Ole A., O'Dushlaine, Colm, Purcell, Shaun M., Sklar, Pamela, Sullivan, Patrick F., Hultman, Christina M., Palmgren, Juni, Magnusson, Patrik K. E.
Publicado 2011

Partitioning heritability by functional annotation using genome-wide association summary statistics

por Finucane, Hilary K., Bulik-Sullivan, Brendan, Gusev, Alexander, Trynka, Gosia, Reshef, Yakir, Loh, Po-Ru, Anttila, Verneri, Xu, Han, Zang, Chongzhi, Farh, Kyle, Ripke, Stephan, Day, Felix R., Consortium, ReproGen, Purcell, Shaun, Stahl, Eli, Lindstrom, Sara, Perry, John R. B., Okada, Yukinori, Raychaudhuri, Soumya, Daly, Mark, Patterson, Nick, Neale, Benjamin M., Price, Alkes L.
Publicado 2015

DIXDC1 contributes to psychiatric susceptibility by regulating dendritic spine and glutamatergic synapse density via GSK3 and Wnt/β-catenin signaling

por Martin, Pierre-Marie, Stanley, Robert E., Ross, Adam P., Freitas, Andiara E., Moyer, Caitlin E., Brumback, Audrey C., Iafrati, Jillian, Stapornwongkul, Kristina S., Dominguez, Sky, Kivimäe, Saul, Mulligan, Kimberly A., Pirooznia, Mehdi, McCombie, W. Richard, Potash, James B., Zandi, Peter P., Purcell, Shaun M., Sanders, Stephan J., Zuo, Yi, Sohal, Vikaas S., Cheyette, Benjamin N.R.
Publicado 2016

SARS-CoV-2 mRNA vaccine induced higher antibody affinity and IgG titers against variants of concern in post-partum vs non-post-partum women

por Lee, Youri, Grubbs, Gabrielle, Ramelli, Sabrina C., Levine, Andrea R., Bathula, Allison, Saharia, Kapil, Purcell, Madeleine, Singireddy, Shreya, Dugan, Colleen L., Kirchoff, Lindsey, Lankford, Allison, Cipriano, Sarah, Curto, Ryan A., Wu, Jocelyn, Raja, Katherine, Kelley, Emily, Herr, Daniel, Vannella, Kevin M., Ravichandran, Supriya, Tang, Juanjie, Harris, Anthony, Sajadi, Mohammad, Chertow, Daniel S., Grazioli, Alison, Khurana, Surender
Publicado 2022

Impact of stereopure chimeric backbone chemistries on the potency and durability of gene silencing by RNA interference

por Liu, Wei, Iwamoto, Naoki, Marappan, Subramanian, Luu, Khoa, Tripathi, Snehlata, Purcell-Estabrook, Erin, Shelke, Juili Dilip, Shah, Himali, Lamattina, Anthony, Pan, Qianli, Schrand, Brett, Favaloro, Frank, Bedekar, Mugdha, Chatterjee, Arindom, Desai, Jigar, Kawamoto, Tomomi, Lu, Genliang, Metterville, Jake, Samaraweera, Milinda, Prakasha, Priyanka Shiva, Yang, Hailin, Yin, Yuan, Yu, Hui, Giangrande, Paloma H, Byrne, Michael, Kandasamy, Pachamuthu, Vargeese, Chandra
Publicado 2023

SARS-CoV-2 mouse adaptation selects virulence mutations that cause TNF-driven age-dependent severe disease with human correlates

por Bader, Stefanie M., Cooney, James P., Sheerin, Dylan, Taiaroa, George, Harty, Leigh, Davidson, Kathryn C., Mackiewicz, Liana, Dayton, Merle, Wilcox, Stephen, Whitehead, Lachlan, Rogers, Kelly L., Georgy, Smitha Rose, Coussens, Anna K., Grimley, Samantha L., Corbin, Vincent, Pitt, Miranda, Coin, Lachlan, Pickering, Raelene, Thomas, Merlin, Allison, Cody C., McAuley, Julie, Purcell, Damian F. J., Doerflinger, Marcel, Pellegrini, Marc
Publicado 2023

Integrated Bayesian analysis of rare exonic variants to identify risk genes for schizophrenia and neurodevelopmental disorders

por Nguyen, Hoang T., Bryois, Julien, Kim, April, Dobbyn, Amanda, Huckins, Laura M., Munoz-Manchado, Ana B., Ruderfer, Douglas M., Genovese, Giulio, Fromer, Menachem, Xu, Xinyi, Pinto, Dalila, Linnarsson, Sten, Verhage, Matthijs, Smit, August B., Hjerling-Leffler, Jens, Buxbaum, Joseph D., Hultman, Christina, Sklar, Pamela, Purcell, Shaun M., Lage, Kasper, He, Xin, Sullivan, Patrick F., Stahl, Eli A.
Publicado 2017

Effects of a patient-derived de novo coding alteration of CACNA1I in mice connect a schizophrenia risk gene with sleep spindle deficits

por Ghoshal, Ayan, Uygun, David S., Yang, Lingling, McNally, James M., Lopez-Huerta, Violeta G., Arias-Garcia, Mario A., Baez-Nieto, David, Allen, Andrew, Fitzgerald, Megan, Choi, Soonwook, Zhang, Qiangge, Hope, Jen M., Yan, Karena, Mao, Xiaohong, Nicholson, Thomas B., Imaizumi, Kazuo, Fu, Zhanyan, Feng, Guoping, Brown, Ritchie E., Strecker, Robert E., Purcell, Shaun M., Pan, Jen Q.
Publicado 2020

Comparative analysis of the AIB1 interactome in breast cancer reveals MTA2 as a repressive partner which silences E-Cadherin to promote EMT and associates with a pro-metastatic phe...

por Varešlija, Damir, Ward, Elspeth, Purcell, Siobhan P., Cosgrove, Nicola S., Cocchiglia, Sinéad, O’Halloran, Philip J., Charmsaz, Sara, Bane, Fiona T., Brett, Francesca M., Farrell, Michael, Cryan, Jane, Beausang, Alan, Hudson, Lance, Turnbul, Arran K., Dixon, J. Michael, Hill, Arnold D. K., Priedigkeit, Nolan, Oesterreich, Steffi, Lee, Adrian V., Sims, Andrew H., Redmond, Aisling M., Carroll, Jason S., Young, Leonie S.
Publicado 2021

Simultaneous evaluation of antibodies that inhibit SARS-CoV-2 variants via multiplex assay

por Lopez, Ester, Haycroft, Ebene R., Adair, Amy, Mordant, Francesca L., O’Neill, Matthew T., Pymm, Phillip, Redmond, Samuel J., Lee, Wen Shi, Gherardin, Nicholas A., Wheatley, Adam K., Juno, Jennifer A., Selva, Kevin J., Davis, Samantha K., Grimley, Samantha L., Harty, Leigh, Purcell, Damian F.J., Subbarao, Kanta, Godfrey, Dale I., Kent, Stephen J., Tham, Wai-Hong, Chung, Amy W.
Publicado 2021

Post-COVID-19 assessment in a specialist clinical service: a 12-month, single-centre, prospective study in 1325 individuals

por Heightman, Melissa, Prashar, Jai, Hillman, Toby E, Marks, Michael, Livingston, Rebecca, Ridsdale, Heidi A, Roy, Kay, Bell, Robert, Zandi, Michael, McNamara, Patricia, Chauhan, Alisha, Denneny, Emma, Astin, Ronan, Purcell, Helen, Attree, Emily, Hishmeh, Lyth, Prescott, Gordon, Evans, Rebecca, Mehta, Puja, Brennan, Ewen, Brown, Jeremy S, Porter, Joanna, Logan, Sarah, Wall, Emma, Dehbi, Hakim-Moulay, Cone, Stephen, Banerjee, Amitava
Publicado 2021

Non-rapid eye movement sleep and wake neurophysiology in schizophrenia

por Kozhemiako, Nataliia, Wang, Jun, Jiang, Chenguang, Wang, Lei A, Gai, Guanchen, Zou, Kai, Wang, Zhe, Yu, Xiaoman, Zhou, Lin, Li, Shen, Guo, Zhenglin, Law, Robert, Coleman, James, Mylonas, Dimitrios, Shen, Lu, Wang, Guoqiang, Tan, Shuping, Qin, Shengying, Huang, Hailiang, Murphy, Michael, Stickgold, Robert, Manoach, Dara, Zhou, Zhenhe, Zhu, Wei, Hal, Mei-Hua, Purcell, Shaun M, Pan, Jen Q
Publicado 2022

Antibody therapy reverses biological signatures of COVID-19 progression

por Maher, M. Cyrus, Soriaga, Leah B., Gupta, Anil, Chen, Yi-Pei, di Iulio, Julia, Ledoux, Sarah, Smithey, Megan J., Cathcart, Andrea L., McKusick, Kathleen, Sun, David, Aldinger, Melissa, Alexander, Elizabeth, Purcell, Lisa, Ding, Xiao, Peppercorn, Amanda, Austin, Daren, Mogalian, Erik, Yeh, Wendy W., Shapiro, Adrienne E., Corti, Davide, Virgin, Herbert W., Pang, Phillip S., Telenti, Amalio
Publicado 2022

VIP152 is a selective CDK9 inhibitor with pre-clinical in vitro and in vivo efficacy in chronic lymphocytic leukemia

por Sher, Steven, Whipp, Ethan, Walker, Janek, Zhang, Pu, Beaver, Larry, Williams, Katie, Orwick, Shelley, Ravikrishnan, Janani, Walker, Brandi, Perry, Elizabeth, Gregory, Charles, Purcell, Matthew, Pan, Alexander, Yan, Pearlly, Alinari, Lapo, Johnson, Amy J., Frigault, Melanie M., Greer, Joy M., Hamdy, Ahmed, Izumi, Raquel, Mo, Xiaokui, Sampath, Deepa, Woyach, Jennifer, Blachly, James, Byrd, John C., Lapalombella, Rosa
Publicado 2022

433. Thromboinflammation in COVID-19 and association with death in patients on ECMO

por Platt, Andrew, Callier, Viviane, Hu, Zonghui, Warner, Seth, Stein, Syndey R, Anders, Megan, Ricotta, Emily, Stantliff, Trevor M, Wu, Jocelyn, Hays, Nicole, Raja, Katherine, Curto, Ryan, Purcell, Madeleine, Ramelli, Sabrina, Ramos-Benitez, Marcos J, Lach, Izabella, Dickey, James, Strich, Jeffrey R, Vannella, Kevin M, Gibbons, Miranda, Tabatabai, Ali, Saharia, Kapil K, Madathil, Ronson, Rabin, Joseph, Grazioli, Alison, Follmann, Dean, Chertow, Daniel S
Publicado 2023