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792881Role of antiangiogenic agents in first-line treatment for advanced NSCLC in the era of immunotherapypor Pang, Lan-Lan, Gan, Jia-Di, Huang, Yi-Hua, Liao, Jun, Zhuang, Wei-Tao, Ali, Wael-Abdullah-Sultan, Hong, Shao-Dong, Zhang, Li, Fang, Wen-Feng“…Outcomes included progression-free survival (PFS), overall survival (OS), objective response rate (ORR), and rate of grade 3–4 toxicity assessment. R-4.3.1 was utilized to perform the analysis. RESULTS: A total of 54 studies with a sample size of 25,046 were finally enrolled. …”
Publicado 2023
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792882“…We performed pairwise comparisons of correlation and slope values using Fischer’s r to z transformation and t-tests, respectively. …”
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792883por Dong, Chao, Luan, Fujuan, Tian, Wenyan, Duan, Kaipeng, Chen, Tao, Ren, Jiayu, Li, Weikang, Li, Dongbao, Zhi, Qiaoming, Zhou, Jin“…RESULTS: By analyzing lncRNA expression data by WGCNA, we found that blue module was highly correlated with GCPM (r = 0.44, p = 0.04) and six lncRNAs involved in this module (DNM3OS, lnc-MFAP2-53, lnc-PPIAL4C-4, lnc-RFNG-1, lnc-TRIM28-14 and lnc-YARS2-4) were identified. …”
Publicado 2023
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792884por Carbajo-García, María Cristina, Juarez-Barber, Elena, Segura-Benítez, Marina, Faus, Amparo, Trelis, Alexandra, Monleón, Javier, Carmona-Antoñanzas, Greta, Pellicer, Antonio, Flanagan, James M., Ferrero, Hortensia“…Differentially expressed genes (FDR < 0.01, log2FC > 1 or < − 1) were selected following DESeq2, edgeR, and limma analysis. Their differential methylation and functional enrichment (FDR < 0.05) were respectively analyzed with limma and ShinyGO. …”
Publicado 2023
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792885por Abdelwahed, Aya Elsayed, Abd-elkader, Mostafa Mahmod, Mahfouz, Amany, Abdelmawla, Mohammed Osama, Kabeel, Marwa, Elkot, Amr Gabr, Hamad, Mohamed Rabiea, Ibrahim, Rahma Abd Elfattah, Ghallab, Marwa M. I., Hamza, Nouran“…Descriptive, univariate, and multivariate regression analyses were applied using IBM SPSS v 26 and R v 4.0.0 software. RESULTS: A total of 8163 participants completed the questionnaire, and 518 participants were excluded from the analysis due to inconsistencies in their data. …”
Publicado 2023
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792886“…CD26(high) cells are enriched with Mucosal Associated Invariant T (MAIT) cells co-expressing CD161TVα7.2 and IL-18Rα. Also, CD26(high) cells have a rich chemokine receptor profile (e.g. …”
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792887por Kaefer, Keitiane, Pierrakos, Charalampos, Nguyen, Thomas, Velissaris, Dimitrios, Attou, Rachid, Devriendt, Jacques, Scolletta, Sabino, Taccone, Fabio Silvio“…A positive correlation was observed between changes in blood lactate and baseline P(va)CO(2)/C(av)O(2) (r = 0.35, p = 0.02). CONCLUSIONS: In critically ill patients with hyperlactatemia, P(va)CO(2)/C(av)O(2) before FB cannot be used to predict decreases in blood-lactate levels after FB. …”
Publicado 2023
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792888“…Furthermore, TCS, TCC, and PCMX showed good linear relationships with their corrected peak areas within a mass concentration range of 1-100 mg/L, and the correlation coefficients (r) were all greater than 0.99. Moreover, the limits of detection (LODs, S/N=3) and limits of quantification (LOQs, S/N=10) were determined to be 0.2 and 1 mg/L, respectively. …”
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792889por Han, Yi, Drobisch, Pascal, Krüger, Alexander, William, Doreen, Grützmann, Konrad, Böthig, Lukas, Polster, Heike, Seifert, Lena, Seifert, Adrian M., Distler, Marius, Pecqueux, Mathieu, Riediger, Carina, Plodeck, Verena, Nebelung, Heiner, Weber, Georg F., Pilarsky, Christian, Kahlert, Ulf, Hinz, Ulf, Roth, Susanne, Hackert, Thilo, Weitz, Jürgen, Wong, Fang Cheng, Kahlert, Christoph“…The results of ddPCR enabled an establishment of a novel prognostic EV mRNA signature consisting of PPP1R12A, SCN7A and SGCD for risk stratification of PDAC patients. …”
Publicado 2023
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792890por Mensah, Felix, Okyere, Joshua, Azure, Simon Agongo, Budu, Eugene, Ameyaw, Edward Kwabena, Seidu, Abdul-Aziz, Ahinkorah, Bright Opoku“…Second, summary measures (D), (PAR), (R), and (PAF) were also employed. A 95% uncertainty interval (UI) was constructed for point estimates to measure statistical significance. …”
Publicado 2023
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792891por Díaz-Regañón, David, García-Sancho, Mercedes, Villaescusa, Alejandra, Sainz, Ángel, Agulla, Beatriz, Reyes-Prieto, Mariana, Rodríguez-Bertos, Antonio, Rodríguez-Franco, Fernando“…Therefore, in this study, we aimed to characterize the intestinal bacterial microbiota in dogs with inflammatory bowel disease (IBD) (n = 34) by means of duodenal biopsies and fecal samples collected at the time of the diagnosis and to compare those to a group of healthy dogs (n = 12) using the 16S ribosomal RNA (16S rRNA) gene-targeted sequencing (Illumina MiSeq platform). …”
Publicado 2023
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792892por Planche, Vincent, Bouteloup, Vincent, Pellegrin, Isabelle, Mangin, Jean-Francois, Dubois, Bruno, Ousset, Pierre-Jean, Pasquier, Florence, Blanc, Frederic, Paquet, Claire, Hanon, Olivier, Bennys, Karim, Ceccaldi, Mathieu, Annweiler, Cédric, Krolak-Salmon, Pierre, Godefroy, Olivier, Wallon, David, Sauvee, Mathilde, Boutoleau-Bretonnière, Claire, Bourdel-Marchasson, Isabelle, Jalenques, Isabelle, Chene, Genevieve, Dufouil, Carole“…All blood biomarkers but total tau were mildly correlated with their equivalence in the CSF (r = 0.33 to 0.46, p < 0.0001) and were associated with amyloid-PET status (p < 0.0001). …”
Publicado 2023
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792893“…There was no correlation with age, abstinence days, semen volume, or percentage of normal-form sperm (r = 0.16, 0.05, 0.04, -0.18, p > 0.05). Compared with IVF-I group, the sperm concentration and PR were decreased in IVF-III group. …”
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792894por Valibouze, Caroline, Speca, Silvia, Dubuquoy, Caroline, Mourey, Florian, M'Ba, Lena, Schneider, Lucil, Titecat, Marie, Foligné, Benoît, Genin, Michaël, Neut, Christel, Zerbib, Philippe, Desreumaux, Pierre“…The levels of adherent LF82 were correlated with anastomotic macroscopic scores in TgB27 rats (r = 0.49, P = 0.006), with a higher risk of POR in animals having high levels of luminal LF82 (71.4% vs 25%, P = 0.02). …”
Publicado 2023
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792895“…All children completed the EQ-5D-Y-3L IA, Moods and Feelings Questionnaire (MFQ), Faces Pain Scale-Revised (FPS-R) and a functional independence measure (WeeFIM) was completed by the researcher. …”
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792896por Zhao, Chunchun, Zhou, Xinxin, Xue, Chuizhao, Lun, Xinchang, Li, Wenyu, Liu, Xiaobo, Wu, Haixia, Song, Xiuping, Wang, Jun, Liu, Qiyong, Meng, Fengxia“…ArcGIS 10.6 software was used to make interpolation and extract meteorological data of collection sites and to conduct spatial autocorrelation analysis. R 4.1.2 software was used to conduct a chi-square test for kdr mutations and dengue area and to analyze the correlation between meteorological factors and kdr mutations. …”
Publicado 2023
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792897por Dedeilia, Aikaterini, Papapanou, Michail, Papadopoulos, Andreas N., Karela, Nina-Rafailia, Androutsou, Anastasia, Mitsopoulou, Dimitra, Nikolakea, Melina, Konstantinidis, Christos, Papageorgakopoulou, Manthia, Sideris, Michail, Johnson, Elizabeth O., Fitzpatrick, Siobhan, Cometto, Giorgio, Campbell, Jim, Sotiropoulos, Marinos G.“…We assessed risk of bias (Newcastle–Ottawa scale for observational studies, RοB2 for randomized controlled trials [RCT]) and rated evidence certainty using GRADE. …”
Publicado 2023
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792898por Chiusole, Benedetta, Tortorelli, Ilaria, Galiano, Antonella, Murtas, Fabio, Ahcene-Djaballah, Selma, Tierno, Giuseppina, Bergo, Eleonora, Banzato, Alberto, Gatti, Maura, Di Maggio, Antonio, Sergi, Giuseppe, Rastrelli, Marco, Sbaraglia, Marta, Zagonel, Vittorina, Brunello, Antonella“…Statistical analysis was performed with R version 3.4.3 Results: Out of 101 pts, with a median age of 77 years, 76 received chemotherapy (75.3%), which was anthracycline-based for 46 pts (60.5%). …”
Publicado 2023
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792899por Hwang, Soyoon, Kwon, Ki Tae, Lee, So Hee, Kim, Shin-Woo, Chang, Hyun-Ha, Kim, Yoonjung, Bae, Sohyun, Cheong, Hae Suk, Park, Se Yoon, Kim, Bongyoung, Lee, Shinwon, Park, Jiho, Heo, Sang Taek, Oh, Won Sup, Kim, Yeonjae, Park, Kyung-Hwa, Kang, Chang Kyung, Oh, NamHee, Lim, Su Jin, Yun, Seongcheol, Son, Ji Woong, Ryoo, Hyun Wook, Chung, Un Sun, Lee, Ju-Yeon, Park, Hye Yoon, Shin, Ji-Yeon, Bae, Sang-geun, Lee, Ji-yeon“…Data were collected using a structured questionnaire and analyzed using the R version 4.1.1 software program. OLBI results indicate clinically exhaustion in 84.5% (1204/1425) and clinically disengagement in 91.1% (1298/1425), and 77.3% (1102/1425) met the score criteria for both the exhaustion and disengagement subscales for burnout. …”
Publicado 2023
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792900por Zhuxiao, Ren, Fang, Xu, Wei, Wei, Shumei, Yang, Jianlan, Wang, Qiuping, Li, Jingjun, Pei, Chuan, Nie, Yongsheng, Li, Zhichun, Feng, Jie, Yang“…FUNDING: This work was supported by 10.13039/501100012166National Key R&D Program of China (2021YFC2701700), 10.13039/501100001809National Natural Science Foundation of China (82101817, 82171714, 8187060625), 10.13039/501100004000Guangzhou science and technology program (202102080104).…”
Publicado 2023
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