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  1. 793081
    “…Stock Owner; Self; Regeneron Pharmaceuticals. R. SinhaRoy: Employee; Self; Regeneron Pharmaceuticals. …”
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    FRI069 Treatment With Mibavademab, A Novel Leptin Receptor Agonist, Is Associated With Improvement In Weight And Associated Comorbidities In Congenital Leptin Deficiency
  2. 793082
    “…Rocha: None. E. Melson: None. R.J. Veen: None. L. Abdi: None. T. McDonnell: None. …”
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    OR20-01 Machine Learning-based Steroid Metabolome Analysis In Women With Polycystic Ovary Syndrome Reveals Three Distinct Androgen Excess Subtypes With Different Metabolic Risk Profiles.
  3. 793083
    “…Disclosure: H. Elenius: None. R. McGlotten: None. A.M. Gharib: None. L.K. Nieman: None. …”
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    THU538 Use Of Multiple Functional And Structural Imaging Modalities Improves Detection Of Ectopic ACTH Tumors
  4. 793084
    “…Guery: None. C. Lasnon: None. R. Ciappuccini: None. M. Sali dauda: None. B. Legrand: None. …”
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    FRI689 First-line F18-choline PET/CT Versus Tc99m-sestaMIBI SPECT/CT In The Surgical Management Of Primary Hyperparathyroidism: The Multicentre APACH2 Phase III Trial
  5. 793085
    “…To explore this possibility, we studied the maternal thyroid function tests (TFT) TSH, FT3, and FT4 throughout the pregnancies from 8 women harboring the R243Q THRB mutation (AfMo) during a total of 10 pregnancies: 6 carrying AfFe and 4 NlFe fetuses. …”
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    OR14-03 The Thyroid Hormone Receptor Beta Genotype Of The Fetus Influences The Maternal Thyroid Function During Pregnancy
  6. 793086
    “…Laycock: None. Y. Lee: None. R. Senanayake: None. J. MacFarlane: None. E. Ng: None. …”
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    THU594 Outcome Data From Fabulas: A Feasibility Study Of Radiofrequency Endoscopic Ablation, With Ultrasound Guidance, As A Non-surgical, Adrenal Sparing Treatment For Aldosterone Producing Adenomas
  7. 793087
    “…Disclosure: S. Maraka: None. R. Owen: None. N.M. Singh Ospina: None. M. Knox: None. …”
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    THU664 Discontinuation Of Low-dose Levothyroxine Therapy For Patients With Subclinical Hypothyroidism Is Feasible: A Pilot, Randomized, Double-blind, Placebo-controlled Trial
  8. 793088
    “…AZP-3601 is a novel 36-amino-acid peptide designed to activate the R(0) conformation of the PTH 1 receptor which produces a prolonged calcemic response despite a short half-life. …”
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    SAT237 AZP-3601, A Novel PTH 1 Receptor Agonist, Induces Rapid Reduction And Normalization Of Urinary Calcium In Chronic Hypoparathyroid Patients
  9. 793089
    “…Stock Owner; Self; Eli Lilly & Company. R. Mody: Employee; Self; Eli Lilly & Company. Stock Owner; Self; Eli Lilly & Company. …”
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    FRI639 Effect Of Early Initiation Of GLP-1 RAs On Weight Reduction Among People With Type 2 Diabetes
  10. 793090
    “…Stock Owner; Self; Novo Nordisk. R.J. Kildemoes: Employee; Self; Novo Nordisk. Stock Owner; Self; Novo Nordisk. …”
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    THU073 Somapacitan Administered Subcutaneously At 5 mg/1.5 mL Or 10 mg/1.5 mL Strengths Yields Clinically Similar PK And IGF-I Profiles In Healthy Participants
  11. 793091
    “…We found a new GV in TP53 (G105D) in a patient who was later found to have a sister with ACC and, for the first time, 3 GVs in ARMC5 (P731R). Patients with ARMC5 GVs had large cortisol-secreting tumors and one case displayed pathologic features of ACC and combined macronodular cortical disease. …”
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    THU616 Analysis Of Germline Mutations In Patients With Sporadic Adrenocortical Carcinoma
  12. 793092
    “…Other; Self; Abbott Diabetes Care. R. Buzzetti: Consulting Fee; Self; Sanofi, Novo Nordisk, Eli Lilly & Company. …”
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    THU296 Effect Of Tirzepatide In GADA-positive Individuals With T2D: A Post Hoc Analysis Of The SURPASS 2-5 Trials
  13. 793093
    “…Funding: CONICET, ANPCYT, Sidus Arg, F. R Barón, F. Williams. Presentation: Saturday, June 17, 2023…”
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    SAT035 Oligonucleotide IMT504 Markedly Improves Metabolic Sindrome And Type 2 Diabetes In High-Fat Diet Fed Mice
  14. 793094
    “…A 90-minute low dose infusion of native GLP-1 (7-36 amide,1 pmol/kg/min) in individuals with overweight and obesity (n=19) did not alter plasma NEPa, which suggests that the attenuating effects on NEPa with GLP-1R agonism is not acute. In conclusion, our data support that plasma NEPa is increased in T2D and NAFLD independent of obesity but may be normalized by bariatric surgery, and that chronic treatment with GLP-1 reduces NEPa. …”
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    SAT032 Circulating Neprilysin Activity Is Increased In Type 2 Diabetes And Fatty Liver Disease, And Reduces Following Bariatric Surgery And Liraglutide Therapy
  15. 793095
    “…At the end of the trial, blood samples were obtained from the fish to evaluate some plasma biochemicals, including aspartate aminotransaminase (AST), alanine aminotransferase (ALT), creatinine (CRE), alkaline phosphatase (ALP), and lactate dehydrogenase (LDH), antioxidant biomarkers, including total antioxidant capacity (TAOC), total superoxide dismutase (TSOD), reduced glutathione (rGSH), and catalase (CAT), stress indicators, including heterophil to lymphocyte (H/L) ratio, cortisol (COR), malondialdehyde (MDA), and myeloperoxidase (MPO), and immunological reactions, including peripheral blood leukocyte proliferation (PBLP), phagocytosis activity (PHG), lysozyme activity (LYS), alternative complement hemolytic action (ACH50), and total immunoglobulin concentration (TIG). …”
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    Dietary propolis complementation relieves the physiological and growth deterioration induced by Flavobacterium columnare infection in juveniles of common carp (Cyprinus carpio)
  16. 793096
    “…When PaO(2) fell below 60 mmHg with VM, respiratory effort increased proportionally (p < 0.01, r = 0.81). CONCLUSIONS: In early COVID-19 pneumonia, Helmet-CPAP increases respiratory effort without altering dynamic stress, while the effects upon static and total stress are variable, requiring individual assessment. …”
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    Effects of CPAP and FiO(2) on respiratory effort and lung stress in early COVID-19 pneumonia: a randomized, crossover study
  17. 793097
    “…Notably, subgroup analysis of our study also found that PFS was significantly better in patients with G719X, L861Q, S768I, G719X+L861Q, and G719X+S768I in Xuanwei than classical mutation ones, including 19-Del and L858R (median 22.7 vs. 12.0 months, HR=0.523, P=0.010), while PFS was inferior in patients with rare mutations of EGFR in non-Xuanwei than the classical mutation ones (median 5.10 vs. 11.10 months, HR=1.760, P=0.015). …”
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    Survival analysis of patients with advanced non-small cell lung cancer receiving EGFR-TKI treatment of Yunnan in southwestern China: a real-world study
  18. 793098
    “…Under optimal conditions, the method showed good linearity (r(2)>0.99). The limits of quantification (S/N≥5) were in the range of 0.003-0.005 μg/mL and 3-5 μg/mL for monoamine and amino acid NTs, respectively, with RSDs of less than 20%. …”
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    磺酸功能化共价有机骨架固相微萃取纤维的制备及其在小鼠脑部神经递质分析中的应用
  19. 793099
    “…Data were collected by a researcher-made checklist, the Spielberger’s State-Trait Anxiety Inventory (STAI), the Pain Visual Assessment Scale (VAS), and the Hollins Martin’s Birth Satisfaction Scale-Revised (BSS-R). Data were analyzed by SPSS-22 statistical software using Kruskal Wallis, Chi-Square, ANOVA and Fisher’s exact tests. …”
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    Comparison of maternal outcomes in caring by Doula, trained lay companion and routine midwifery care
  20. 793100
    “…However, the causal relationship between the expression level of IL-17 or IL-17 receptor (IL-17R) and RA remained unknown. In this study, two-sample Mendelian randomization (MR) was used to investigate the causal relationship between IL-17 and RA. …”
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    Genetic association between interleukin-17 and susceptibility to rheumatoid arthritis
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