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  1. 793181
    “…The differentially expressed genes (DEGs) and miRNAs (DE miRNAs) were identified by R software. Gene Ontology (GO) enrichment and Kyoto Encyclopedia of genes and genomes (KEGG) pathway analysis were used to assess the potential molecular mechanisms of DEGs. …”
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    Identification of latent biomarkers in connection with progression and prognosis in oral cancer by comprehensive bioinformatics analysis
  2. 793182
    por Liu, Jun, Li, Dan-Dan, Dong, Wei, Liu, Yu-Qi, Wu, Yang, Tang, Da-Xuan, Zhang, Fu-Chun, Qiu, Meng, Hua, Qi, He, Jing-Yu, Li, Jun, Du, Bai, Du, Ting-Hai, Niu, Lin-Lin, Jiang, Xue-Jun, Cui, Bo, Chen, Jiang-Bin, Wang, Yang-Gan, Wang, Hai-Rong, Yu, Qin, He, Jing, Mao, Yi-Lin, Bin, Xiao-Fang, Deng, Yue, Tian, Yu-Dan, Han, Qing-Hua, Liu, Da-Jin, Duan, Li-Qin, Zhao, Ming-Jun, Zhang, Cui-Ying, Dai, Hai-Ying, Li, Ze-Hua, Xiao, Ying, Hu, You-Zhi, Huang, Xiao-Yu, Xing, Kun, Jiang, Xin, Liu, Chao-Feng, An, Jing, Li, Feng-Chun, Tao, Tao, Jiang, Jin-Fa, Yang, Ying, Dong, Yao-Rong, Zhang, Lei, Fu, Guang, Li, Ying, Huang, Shu-Wei, Dou, Li-Ping, Sun, Lan-Jun, Zhao, Ying-Qiang, Li, Jie, Xia, Yun, Liu, Jun, Liu, Fan, He, Wen-Jin, Li, Ying, Tan, Jian-Cong, Lin, Yang, Zhou, Ya-Bin, Yang, Jian-Fei, Ma, Guo-Qing, Chen, Hui-Jun, Liu, He-Ping, Liu, Zong-Wu, Liu, Jian-Xiong, Luo, Xiao-Jia, Bin, Xiao-Hong, Yu, Ya-Nan, Dang, Hai-Xia, Li, Bing, Teng, Fei, Qiao, Wang-Min, Zhu, Xiao-Long, Chen, Bing-Wei, Chen, Qi-Guang, Shen, Chun-Ti, Wang, Yong-Yan, Chen, Yun-Dai, Wang, Zhong
    Publicado 2021
    “…We assessed the modular flexibility of this ETM using the global topological D value based on Euclidean distance, which is correlated with phenotype alteration (r(2): 0.8204, P = 0.019) by linear regression. …”
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    Detection of an anti-angina therapeutic module in the effective population treated by a multi-target drug Danhong injection: a randomized trial
  3. 793183
    “…Median illness duration was 6 days (IQR 3–11) versus 3 days (2–7) in children testing negative, and was positively associated with age (Spearman's rank-order r(s) 0·19, p<0·0001). Median illness duration was longer for older children (7 days, IQR 3–12) than younger children (5 days, 2–9). 77 (4·4%) of 1734 children had illness duration of at least 28 days, more commonly in older than younger children (59 [5·1%] of 1146 older children vs 18 [3·1%] of 588 younger children; p=0·046). …”
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    Illness duration and symptom profile in symptomatic UK school-aged children tested for SARS-CoV-2
  4. 793184
    “…The determination coefficient (R(2)) was used to evaluate the goodness of fit of the model simulation. …”
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    Impact of interventions on the incidence of natural focal diseases during the outbreak of COVID-19 in Jiangsu Province, China
  5. 793185
    “…At the same time the transmural helix angle (HA) gradient was steeper in the chronic follow-up and a correlation between longitudinal strain and transmural HA gradient was detected (r = 0.59 with p < 0.05). Comparing non-gadolinium enhanced data T2 mapping showed the largest relative change between infarct and remote during the acute stage (+ 33 ± 4% day 6, with p = 0.013 T2 vs. …”
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    Cardiovascular magnetic resonance imaging of functional and microstructural changes of the heart in a longitudinal pig model of acute to chronic myocardial infarction
  6. 793186
    “…Plasma IPMS-WashU Aβ42/40 and IPMS-Shim Aβ42/40 showed highest coefficients for correlations with CSF Aβ42/40 (r range, 0.56-0.65). The BioFINDER results were replicated in the Alzheimer Disease Neuroimaging Initiative cohort (mean [SD] age, 72.4 [5.4] years; 43.4% women), where the IP-MS-WashU assay performed significantly better than the IP-MS-UGOT, IA-Elc, IA-N4PE, and IA-Quan assays but not the IP-MS-Shim assay. …”
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    Head-to-Head Comparison of 8 Plasma Amyloid-β 42/40 Assays in Alzheimer Disease
  7. 793187
    “…There was a strongly correlated (r = 0.74) increase in f(max99) (10.5 ± 2.2, range: 7.1–16.4 Hz) with increasing heart rate. …”
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    Quantitative assessment of velocity and flow using compressed SENSE in children and young adults with adequate acquired temporal resolution
  8. 793188
    “…Detection of peaks was done using HOMER (v2.6); differential expressed genes were identified using moderated t-test (limma R-package) and functionally annotated with g:Profiler. …”
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    ASB2 is a direct target of FLI1 that sustains NF-κB pathway activation in germinal center-derived diffuse large B-cell lymphoma
  9. 793189
    “…D.A.L. is a UK National Institute for Health Research Senior Investigator (NF-SI-0611-10196) and is supported by the US National Institutes of Health (R01 DK10324) and a European Research Council Advanced Grant (DevelopObese; 669545). …”
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    Body mass index and subfertility: multivariable regression and Mendelian randomization analyses in the Norwegian Mother, Father and Child Cohort Study
  10. 793190
    “…All analysis were done using R Statistical 3.5.0. RESULTS: MDR-TB was more identified among patients who lived in rural areas (51.3%), in patients’ residence (69.2%) and among those with a household size of six or more family members (59.5%). …”
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    Key factors influencing multidrug-resistant tuberculosis in patients under anti-tuberculosis treatment in two centres in Burundi: a mixed effect modelling study
  11. 793191
    “…Les données démographiques, cliniques et thérapeutiques, les comorbidités, de ces jeunes patients ainsi que des données sur l’infection par le SARS-CoV-2, l’issue et l’impact sur l’activité de la maladie inflammatoire (RMD) ont été documentés par un questionnaire SARS-CoV-2 spécifique mis en œuvre par la FAI2R. RÉSULTATS: D’avril 2020 à juin 2021, des données ont été recueillies auprès de 95 patients âgés de 13,1 ± 4,4 ans, de prédominance féminine (62,1 %), atteints de RMD : une arthrite juvénile idiopathique 44 (46,3 %), maladie auto-inflammatoire 6 (6,3 %), vascularite 1(1,1 %) et maladie systémique auto-immune 37 (39 %), avec un diagnostic hautement suspecté/confirmé de COVID-19. 33 patients (34,7 %) ont reçu des DMARDS, 35 (36,84 %) des bioDMARD,10 (10,6 %) des glucocorticoïdes systémiques et 11(11,7 %) des AINS. …”
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    Caractéristiques cliniques de la Covid-19 chez les enfants et adolescents atteints de maladies rhumatismales et inflammatoires : données de la cohorte française RMD COVID-19 de 95 patients
  12. 793192
    “…Because cephalexin has a similar R1 side chain to aminopenicillins, five patients with an aminopenicillin allergy who received cephalexin were evaluated separately; none had an allergic reaction (Table 1, Table 2, Figure 2). …”
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    143. Use of First-Generation Cephalosporins in Patients with Serious Penicillin Allergies
  13. 793193
    “…Lindholm, MD, American Board of Internal Medicine (Individual(s) Involved: Self): Member of Auxiliary R&D Infectious Disease Item-Writer Task Force. …”
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    34. Long-term clinical outcomes following SARS-CoV-2 infection include persistent symptoms and cardiovascular disease beyond 3 months post-infection
  14. 793194
    por Grose, Andrew, McLeod, Rima
    Publicado 2021
    “…World Health Organization A.S.S.U.R.E.D. criteria [Image: see text] These are criteria for ideal screening or diagnostic tests, as described in a September 2017 paper in the Bulletin of the World Health Organization. …”
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    724. LDBIO Toxoplasma Test in the United States and Beyond: Review of the Device’s Performance on U.S. Samples and its Ability to Avoid False Positives
  15. 793195
    “…Results from recent multicenter clinical trials evaluating this approach demonstrate prolonged survival and increased complete surgical resection rates (R0). Currently, tumor response to neoadjuvant therapy is monitored using computed tomography (CT) following the RECIST 1.1 criteria. …”
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    Overview and Future Perspectives on Tumor-Targeted Positron Emission Tomography and Fluorescence Imaging of Pancreatic Cancer in the Era of Neoadjuvant Therapy
  16. 793196
    por Santos García, Diego, de Deus Fonticoba, Teresa, Cores, Carlos, Muñoz, Guillermo, Paz González, Jose M., Martínez Miró, Cristina, Suárez, Ester, Jesús, Silvia, Aguilar, Miquel, Pastor, Pau, Planellas, Lluis, Cosgaya, Marina, García Caldentey, Juan, Caballol, Nuria, Legarda, Inés, Hernández Vara, Jorge, Cabo, Iria, López Manzanares, Luis, González Aramburu, Isabel, Ávila Rivera, María A., Catalán, Maria J., Nogueira, Víctor, Puente, Víctor, Ruíz de Arcos, María, Borrué, Carmen, Solano Vila, Berta, Álvarez Sauco, María, Vela, Lydia, Escalante, Sonia, Cubo, Esther, Carrillo Padilla, Francisco, Martínez Castrillo, Juan C., Sánchez Alonso, Pilar, Alonso Losada, Maria G., López Ariztegui, Nuria, Gastón, Itziar, Clavero, Pedro, Kulisevsky, Jaime, Blázquez Estrada, Marta, Seijo, Manuel, Rúiz Martínez, Javier, Valero, Caridad, Kurtis, Mónica, de Fábregues, Oriol, González Ardura, Jessica, Ordás, Carlos, López Díaz, Luis M., McAfee, Darrian, Martinez-Martin, Pablo, Mir, Pablo
    Publicado 2021
    “…To be younger (OR = 0.896; 95% CI 0.829–0.968; p = 0.006), to be a female (OR = 4.181; 95% CI 1.422–12.290; p = 0.009), and to have a greater increase in BDI-II (Beck Depression Inventory-II) (OR = 1.139; 95% CI 1.053–1.231; p = 0.001) and NMSS (Non-Motor Symptoms Scale) (OR = 1.052; 95% CI 1.027–1.113; p < 0.0001) total scores from V0 to V2 were associated with clinically significant HRQoL impairment at the 2-year follow-up (Hosmer–Lemeshow test, p = 0.665; R (2) = 0.655). An increase in ≥5 and ≥10 points of BDI-II and NMSS total score at V2 multiplied the probability of presenting clinically significant HRQoL impairment by 5 (OR = 5.453; 95% CI 1.663–17.876; p = 0.005) and 8 (OR = 8.217; 95% CI, 2.975–22.696; p = 0.002), respectively. …”
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    Predictors of clinically significant quality of life impairment in Parkinson’s disease
  17. 793197
    “…Confirmed by Spearman’s rank correlation analysis, neurodevelopmental outcomes were significantly predicted by the 1st aEEG Burdjalov score (r = 0.603, P = 0.001). An abnormal 1st Burdjalov score has predictive value for neurodevelopmental delay with high specificity (84.62%) and positive predictive value (80.00%). …”
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    Early aEEG can predict neurodevelopmental outcomes at 12 to 18 month of age in VLBWI with necrotizing enterocolitis: a cohort study
  18. 793198
    “…Lindholm, MD, American Board of Internal Medicine (Individual(s) Involved: Self): Member of Auxiliary R&D Infectious Disease Item-Writer Task Force. …”
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    337. SARS-CoV-2 Viral Load Does Not Predict Incident Venous Thromboembolism in COVID-19
  19. 793199
    “…À 3 mois (n = 48), la DLCO était négativement corrélée à la valeur du KL-6 initial (r = −0,47, p = 0,001), ce qui n’était pas le cas de la CVF, de la VEMS et du score mMRC. …”
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    Valeur pronostique du KL-6 initial (Krebs von den Lungen 6) au cours de la pneumopathie à SARS-CoV-2
  20. 793200
    “…The receptor-binding domain of the ApoE then combines with low-density lipoprotein receptor (LDLr) and LDLr-related protein 1 receptor (LRP1r) expressed in the blood–brain barrier and glioma, effectively mediating brain-targeted delivery. …”
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    Novel brain-targeted nanomicelles for anti-glioma therapy mediated by the ApoE-enriched protein corona in vivo
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